CamptodactylyNCT07786701
Treatment of Camptodactyly With Radial Longitudinal Flap Versus Full-Thickness Skin Graft
A study testing Radial Longitudinal Flap and Full-Thickness Skin Graft in people with Camptodactyly, run by Associação de Assistência a Criança Deficiente at 1 site in Brazil.
Trial summary
The goal of this randomized clinical trial is to compare two surgical techniques used for skin coverage after surgical correction of camptodactyly, a condition in which one or more fingers remain bent and cannot be fully straightened. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Camptodactyly
- What is being tested?
- Radial Longitudinal Flap and Full-Thickness Skin Graft
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 42 participants
- Where
- 1 siteBrazil
- Study dates
- 2 Sep 2026to 1 Sep 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Who may be able to join
- Diagnosis of camptodactyly.
- Flexion contracture of the proximal interphalangeal joint ≥30°.
- Indication for surgical treatment.
- Written informed consent from adult participants or from parents/legal guardians for minors.
- Assent from minor participants, when applicable.
Who cannot join
- Associated syndromes that may interfere with isolated assessment of camptodactyly (e.g., arthrogryposis).
- Previous surgery on the affected finger.
- Irreversible fixed joint stiffness.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Treatment of Camptodactyly With Radial Longitudinal Flap Versus Full-Thickness Skin Graft: A Randomized, Parallel, Superiority Clinical Trial
The goal of this randomized clinical trial is to compare two surgical techniques used for skin coverage after surgical correction of camptodactyly, a condition in which one or more fingers remain bent and cannot be fully straightened. The study will include children and adolescents with camptodactyly who have a proximal interphalangeal joint flexion contracture of 30 degrees or more and an indication for surgical treatment.
The main question the study aims to answer is:
Read more
- Does a radial longitudinal flap provide better gain and maintenance of finger extension six months after surgery compared with a full-thickness skin graft?
The study will also evaluate:
- Movement of the affected finger;
- Recurrence of the deformity;
- Surgical complications;
- Hand function;
- Patient and/or parent or caregiver satisfaction;
- Adherence to rehabilitation and nighttime splint use;
- Overall surgical outcome.
Researchers will compare radial longitudinal flap and full-thickness skin graft to determine whether the radial longitudinal flap provides better maintenance of finger correction.
Participants will:
- Undergo the surgical treatment indicated for camptodactyly, with skin coverage using either a radial longitudinal flap or a full-thickness skin graft, according to randomization;
- Be evaluated before surgery and at 2, 4, 8, and 12 weeks and 6 months after surgery;
- Have movement of the affected finger assessed using standardized goniometry;
- Follow the postoperative rehabilitation protocol, including occupational therapy and nighttime extension splint use;
- Complete assessments of hand function and satisfaction at the scheduled evaluation periods.
- Approximately 42 eligible fingers will be randomized, with 21 fingers allocated to each treatment group. If a participant has more than one eligible finger, each eligible finger may be randomized independently.
Read the detailed description
Camptodactyly is a congenital hand deformity characterized by flexion contracture of the proximal interphalangeal (PIP) joint, resulting in an inability to fully extend the affected finger. The condition may involve one or more fingers and may be unilateral or bilateral. Although conservative treatment is preferred in many cases, surgical treatment may be indicated in patients with persistent, moderate, or severe deformity and functional limitation.
Surgical correction generally involves release of contracted structures responsible for the deformity. Following release, a skin defect may remain on the volar aspect of the finger and requires appropriate soft tissue coverage. Full-thickness skin grafting is a commonly used technique; however, secondary scar contraction may contribute to loss of correction or recurrence of the deformity. A radial longitudinal flap provides local tissue coverage and may offer advantages related to tissue elasticity, vascularity, and resistance to secondary contracture.
This study is a prospective, randomized, parallel-group, superiority clinical trial designed to compare radial longitudinal flap coverage with full-thickness skin graft coverage following surgical correction of camptodactyly.
Eligible fingers will be randomly allocated in a 1:1 ratio to one of two treatment groups. Randomization will be performed using a computer-generated sequence with block randomization. Allocation will be concealed using sequentially numbered, opaque, sealed envelopes. Randomization will occur at the level of the eligible finger rather than at the participant level.
When a participant has more than one eligible finger, each eligible finger may be randomized independently. Therefore, a single participant may contribute more than one randomized finger and may potentially receive different treatment techniques for different eligible fingers. The potential correlation between fingers belonging to the same participant will be considered during statistical analysis.
All participants will undergo the surgical treatment indicated for their camptodactyly according to the standardized study protocol. After release of the contracted structures, participants will receive skin coverage according to their randomized treatment allocation.
In the experimental group, the skin defect will be covered using a radial longitudinal flap. In the comparator group, the skin defect will be covered using a full-thickness skin graft obtained from an appropriate donor site according to the surgical protocol.
Postoperative care will follow a standardized rehabilitation protocol. Participants will receive appropriate immobilization and occupational therapy, including exercises directed at maintaining and improving finger range of motion. Nighttime extension splint use will also be prescribed according to the postoperative protocol.
Clinical assessments will be performed before surgery and during postoperative follow-up at 2 weeks, 4 weeks, 8 weeks, 12 weeks, and 6 months. Finger range of motion will be assessed using standardized goniometry. The main objective is to determine whether the radial longitudinal flap provides greater maintenance of PIP joint extension at 6 months compared with full-thickness skin grafting.
Postoperative assessments will be performed by an occupational therapist who will be blinded to treatment allocation. To maintain blinding, the operated finger and donor area will be covered with a self-adherent elastic bandage before assessment, preventing the evaluator from identifying the type of skin coverage used.
In addition to range of motion, the study will evaluate recurrence of the deformity, postoperative complications, hand function, patient and/or parent or caregiver satisfaction, adherence to occupational therapy, nighttime splint use, and overall surgical outcome according to the clinical classification proposed by Siegert et al.
Participants who discontinue follow-up, withdraw consent, or do not complete all scheduled assessments will not be considered excluded from the study after enrollment. They will be recorded as losses to follow-up or study discontinuations, including the reason whenever available. Data collected before discontinuation will be retained and analyzed according to the statistical analysis plan and applicable ethical requirements.
The study is intended to determine whether radial longitudinal flap coverage provides superior maintenance of surgical correction compared with full-thickness skin grafting. The findings may contribute to improving the surgical management of children and adolescents with camptodactyly and help inform the choice of soft tissue coverage following surgical release.
- Conditions
- Camptodactyly
- Being tested
- Radial Longitudinal Flap, Full-Thickness Skin Graft
- Keywords
- Camptodactyly, Hand Surgery, Radial Longitudinal Flap, Full-Thickness Skin Graft, Randomized Clinical Trial, Congenital Hand Deformity
- Medical subject headings
- Hand Deformities, Congenital
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Radial Longitudinal FlapProcedure or surgery
Surgical coverage of the skin defect created after standardized release of the contracted structures in patients with camptodactyly, using a radial longitudinal flap raised from the radial aspect of the affected finger and transposed to cover the resulting volar defect.
Full-Thickness Skin GraftProcedure or surgery
Surgical coverage of the skin defect created after standardized release of the contracted structures in patients with camptodactyly, using a full-thickness skin graft. The graft will be harvested from the wrist flexion crease or hypothenar region according to the standardized surgical protocol.
| Study group | Role | What they receive |
|---|---|---|
| Radial Longitudinal Flap | Experimental | Participants randomized to this arm will undergo surgical correction of camptodactyly with standardized stepwise release of the contracted structures. After adequate release and correction of the proximal interphalangeal joint contracture, the resulting skin defect will be covered using a radial longitudinal flap to provide local soft-tissue coverage of the volar aspect of the affected finger. Postoperative immobilization and rehabilitation will be performed according to the standardized study protocol, including occupational therapy and nighttime extension splint use. Participants will undergo clinical assessments before surgery and at 2, 4, 8, and 12 weeks and 6 months after surgery. Receives: Procedure: Radial Longitudinal Flap |
| Full-Thickness Skin Graft | Active comparator | Participants randomized to this arm will undergo surgical correction of camptodactyly with standardized stepwise release of the contracted structures. After adequate release and correction of the proximal interphalangeal joint contracture, the resulting skin defect will be covered using a full-thickness skin graft. The graft will be harvested from the wrist flexion crease or hypothenar region, according to the standardized surgical protocol. Postoperative immobilization and rehabilitation will be performed according to the standardized study protocol, including occupational therapy and nighttime extension splint use. Participants will undergo clinical assessments before surgery and at 2, 4, 8, and 12 weeks and 6 months after surgery. Receives: Procedure: Full-Thickness Skin Graft |
What is being measured
The primary outcome is the main question the study is designed to answer.
Maintenance of proximal interphalangeal joint extension
The primary outcome will be the gain and maintenance of proximal interphalangeal joint extension, measured by goniometry in degrees.
Measured: From baseline (preoperative assessment) to 6 months after surgery
Secondary outcomes (8)
Active and Passive Range of Motion of the Proximal Interphalangeal Joint
Active and passive range of motion of the proximal interphalangeal joint will be measured by goniometry in degrees at each postoperative assessment.
Measured: Baseline, 2, 4, 8, and 12 weeks, and 6 months after surger
Recurrence of Camptodactyly
Recurrence will be defined as a loss of more than 20 degrees of the extension achieved immediately after surgery, measured by goniometry during follow-up.
Measured: 2, 4, 8, and 12 weeks, and 6 months after surgery
Postoperative Complications
Postoperative complications will include partial or total flap or graft necrosis, wound dehiscence, infection requiring antibiotic treatment, residual pain, and joint stiffness. Partial necrosis will be defined as loss of viability involving less than 50% of the flap or graft area, and total necrosis as loss involving more than 50%. Joint stiffness will be defined as a loss of more than 20 degrees of range of motion compared with the immediate postoperative assessment.
Measured: From surgery through 6 months after surgery
Upper Extremity Function
Upper extremity function will be assessed using the Quick Disabilities of the Arm, Shoulder and Hand (Quick-DASH) questionnaire. The questionnaire will be administered preoperatively and at 6 months after surgery, when appropriate according to the participant's age and ability to complete the instrument.
Measured: Baseline and 6 months after surgery
Patient or Caregiver Satisfaction
Patient or caregiver satisfaction with the postoperative result will be assessed using a visual analog scale ranging from 0 (completely dissatisfied) to 10 (completely satisfied).
Measured: 6 months after surgery
Adherence to Nighttime Extension Splint Use
Adherence to prescribed nighttime extension splint use will be assessed by patient or caregiver self-report. Adequate adherence will be defined as use of the splint on at least 80% of the prescribed nights.
Measured: From initiation of rehabilitation until 6 months after surgery
Adherence to Rehabilitation Protocol
Adherence to the rehabilitation protocol will be assessed according to attendance at scheduled occupational therapy sessions. Adequate adherence will be defined as attendance at least 75% of the prescribed therapy sessions.
Measured: From initiation of rehabilitation until 6 months after surgery
Surgical Outcome According to the Siegert Classification
Surgical outcomes will be classified according to the Siegert et al. classification as excellent, good, fair, or poor, based on correction of extension, gain in extension, loss of flexion, and overall range of motion.
Measured: 6 months after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Aug 2026
- Study start2 Sep 2026
- Primary completion1 Sep 2028 (estimated)
- Study completion1 Sep 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for CamptodactylyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 42 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Associação de Assistência a Criança Deficiente
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Renato Tadeu Sassmannshausen Moretto, Associação de Assistência a Criança Deficiente
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07786701
- Sponsor's protocol ID
- 314.2026
- Other IDs
- CAAE: 99290226.2.0000.0085
- Status last verified
- Sep 2026
- First submitted
- 13 Aug 2026
- Last updated
- 3 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared publicly. Given the pediatric population and the small sample size, even de-identified individual-level data may present a risk of participant re-identification.
Publications
Wall LB, Ezaki M, Goldfarb CA. Camptodactyly Treatment for the Lesser Digits. J Hand Surg Am. 2018 Sep;43(9):874.e1-874.e4. doi: 10.1016/j.jhsa.2018.03.023. Epub 2018 Apr 22.
PubMed 29691077Morimoto Y, Sogabe Y, Kawabata A, Takamatsu K. Digital artery perforator flap transfer for volar soft tissue defect due to dissociation from joint contracture in camptodactyly. JPRAS Open. 2020 Nov 30;27:48-52. doi: 10.1016/j.jpra.2020.11.009. eCollection 2021 Mar.
PubMed 33319010Liao W, Wang L, Tang Y, Jiang L, Guo R, Zhuang H, Tang K, Zheng P. Modified radial tongue-shaped flap following stepwise surgical release for Benson type I camptodactyly of the 5th digit. Sci Rep. 2023 Mar 9;13(1):3927. doi: 10.1038/s41598-023-31138-1.
PubMed 36894622Evans BT, Waters PM, Bae DS. Early Results of Surgical Management of Camptodactyly. J Pediatr Orthop. 2017 Jul/Aug;37(5):e317-e320. doi: 10.1097/BPO.0000000000000967.
PubMed 28277466Yannascoli SM, Goldfarb CA. Treating Congenital Proximal Interphalangeal Joint Contracture. Hand Clin. 2018 May;34(2):237-249. doi: 10.1016/j.hcl.2017.12.013.
PubMed 29625643
Study at a glance
From the registry record, last updated by the sponsor on 3 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Treatment of Camptodactyly With Radial Longitudinal Flap Versus Full-Thickness Skin Graft: A Randomized, Parallel, Superiority Clinical Trial
- ClinicalTrials.gov ID
- NCT07786701
- Acronym / sponsor ID
- 314.2026
- Conditions
- Camptodactyly
- Keywords
- Camptodactyly, Hand Surgery, Radial Longitudinal Flap, Full-Thickness Skin Graft, Randomized Clinical Trial, Congenital Hand Deformity
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 42 participants (estimated)
- Lead sponsor
- Associação de Assistência a Criança DeficienteUniversity, hospital or other
- Study start
- 2 Sep 2026 (actual)
- Primary completion
- 1 Sep 2028 (estimated)
- Study completion
- 1 Sep 2028 (estimated)
- First posted
- 26 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this randomized clinical trial is to compare two surgical techniques used for skin coverage after surgical correction of camptodactyly, a condition in which one or more fingers remain bent and cannot be fully straightened. The study will include children and adolescents with camptodactyly who have a proximal interphalangeal joint flexion contracture of 30 degrees or more and an indication for surgical treatment.
The main question the study aims to answer is:
- Does a radial longitudinal flap provide better gain and maintenance of finger extension six months after surgery compared with a full-thickness skin graft?
The study will also evaluate:
- Movement of the affected finger;
- Recurrence of the deformity;
- Surgical complications;
- Hand function;
- Patient and/or parent or caregiver satisfaction;
- Adherence to rehabilitation and nighttime splint use;
- Overall surgical outcome.
Researchers will compare radial longitudinal flap and full-thickness skin graft to determine whether the radial longitudinal flap provides better maintenance of finger correction.
Participants will:
- Undergo the surgical treatment indicated for camptodactyly, with skin coverage using either a radial longitudinal flap or a full-thickness skin graft, according to randomization;
- Be evaluated before surgery and at 2, 4, 8, and 12 weeks and 6 months after surgery;
- Have movement of the affected finger assessed using standardized goniometry;
- Follow the postoperative rehabilitation protocol, including occupational therapy and nighttime extension splint use;
- Complete assessments of hand function and satisfaction at the scheduled evaluation periods.
- Approximately 42 eligible fingers will be randomized, with 21 fingers allocated to each treatment group. If a participant has more than one eligible finger, each eligible finger may be randomized independently.
Detailed description
Camptodactyly is a congenital hand deformity characterized by flexion contracture of the proximal interphalangeal (PIP) joint, resulting in an inability to fully extend the affected finger. The condition may involve one or more fingers and may be unilateral or bilateral. Although conservative treatment is preferred in many cases, surgical treatment may be indicated in patients with persistent, moderate, or severe deformity and functional limitation.
Surgical correction generally involves release of contracted structures responsible for the deformity. Following release, a skin defect may remain on the volar aspect of the finger and requires appropriate soft tissue coverage. Full-thickness skin grafting is a commonly used technique; however, secondary scar contraction may contribute to loss of correction or recurrence of the deformity. A radial longitudinal flap provides local tissue coverage and may offer advantages related to tissue elasticity, vascularity, and resistance to secondary contracture.
This study is a prospective, randomized, parallel-group, superiority clinical trial designed to compare radial longitudinal flap coverage with full-thickness skin graft coverage following surgical correction of camptodactyly.
Eligible fingers will be randomly allocated in a 1:1 ratio to one of two treatment groups. Randomization will be performed using a computer-generated sequence with block randomization. Allocation will be concealed using sequentially numbered, opaque, sealed envelopes. Randomization will occur at the level of the eligible finger rather than at the participant level.
When a participant has more than one eligible finger, each eligible finger may be randomized independently. Therefore, a single participant may contribute more than one randomized finger and may potentially receive different treatment techniques for different eligible fingers. The potential correlation between fingers belonging to the same participant will be considered during statistical analysis.
All participants will undergo the surgical treatment indicated for their camptodactyly according to the standardized study protocol. After release of the contracted structures, participants will receive skin coverage according to their randomized treatment allocation.
In the experimental group, the skin defect will be covered using a radial longitudinal flap. In the comparator group, the skin defect will be covered using a full-thickness skin graft obtained from an appropriate donor site according to the surgical protocol.
Postoperative care will follow a standardized rehabilitation protocol. Participants will receive appropriate immobilization and occupational therapy, including exercises directed at maintaining and improving finger range of motion. Nighttime extension splint use will also be prescribed according to the postoperative protocol.
Clinical assessments will be performed before surgery and during postoperative follow-up at 2 weeks, 4 weeks, 8 weeks, 12 weeks, and 6 months. Finger range of motion will be assessed using standardized goniometry. The main objective is to determine whether the radial longitudinal flap provides greater maintenance of PIP joint extension at 6 months compared with full-thickness skin grafting.
Postoperative assessments will be performed by an occupational therapist who will be blinded to treatment allocation. To maintain blinding, the operated finger and donor area will be covered with a self-adherent elastic bandage before assessment, preventing the evaluator from identifying the type of skin coverage used.
In addition to range of motion, the study will evaluate recurrence of the deformity, postoperative complications, hand function, patient and/or parent or caregiver satisfaction, adherence to occupational therapy, nighttime splint use, and overall surgical outcome according to the clinical classification proposed by Siegert et al.
Participants who discontinue follow-up, withdraw consent, or do not complete all scheduled assessments will not be considered excluded from the study after enrollment. They will be recorded as losses to follow-up or study discontinuations, including the reason whenever available. Data collected before discontinuation will be retained and analyzed according to the statistical analysis plan and applicable ethical requirements.
The study is intended to determine whether radial longitudinal flap coverage provides superior maintenance of surgical correction compared with full-thickness skin grafting. The findings may contribute to improving the surgical management of children and adolescents with camptodactyly and help inform the choice of soft tissue coverage following surgical release.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Radial Longitudinal Flap | Experimental | Procedure: Radial Longitudinal FlapParticipants randomized to this arm will undergo surgical correction of camptodactyly with standardized stepwise release of the contracted structures. After adequate release and correction of the proximal interphalangeal joint contracture, the resulting skin defect will be covered using a radial longitudinal flap to provide local soft-tissue coverage of the volar aspect of the affected finger. Postoperative immobilization and rehabilitation will be performed according to the standardized study protocol, including occupational therapy and nighttime extension splint use. Participants will undergo clinical assessments before surgery and at 2, 4, 8, and 12 weeks and 6 months after surgery. |
| Full-Thickness Skin Graft | Active comparator | Procedure: Full-Thickness Skin GraftParticipants randomized to this arm will undergo surgical correction of camptodactyly with standardized stepwise release of the contracted structures. After adequate release and correction of the proximal interphalangeal joint contracture, the resulting skin defect will be covered using a full-thickness skin graft. The graft will be harvested from the wrist flexion crease or hypothenar region, according to the standardized surgical protocol. Postoperative immobilization and rehabilitation will be performed according to the standardized study protocol, including occupational therapy and nighttime extension splint use. Participants will undergo clinical assessments before surgery and at 2, 4, 8, and 12 weeks and 6 months after surgery. |
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (5 listed)
- Diagnosis of camptodactyly.
- Flexion contracture of the proximal interphalangeal joint ≥30°.
- Indication for surgical treatment.
- Written informed consent from adult participants or from parents/legal guardians for minors.
- Assent from minor participants, when applicable.
Key exclusion criteria (3 listed)
- Associated syndromes that may interfere with isolated assessment of camptodactyly (e.g., arthrogryposis).
- Previous surgery on the affected finger.
- Irreversible fixed joint stiffness.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Radial Longitudinal FlapSurgical coverage of the skin defect created after standardized release of the contracted structures in patients with camptodactyly, using a radial longitudinal flap raised from the radial aspect of the affected finger and transposed to cover the resulting volar defect. | Procedure or surgery | Radial Longitudinal Flap |
| Full-Thickness Skin GraftSurgical coverage of the skin defect created after standardized release of the contracted structures in patients with camptodactyly, using a full-thickness skin graft. The graft will be harvested from the wrist flexion crease or hypothenar region according to the standardized surgical protocol. | Procedure or surgery | Full-Thickness Skin Graft |
Primary outcome
Maintenance of proximal interphalangeal joint extension
Time frame: From baseline (preoperative assessment) to 6 months after surgery
The primary outcome will be the gain and maintenance of proximal interphalangeal joint extension, measured by goniometry in degrees.
8 secondary outcomes
Active and Passive Range of Motion of the Proximal Interphalangeal Joint
Time frame: Baseline, 2, 4, 8, and 12 weeks, and 6 months after surger
Recurrence of Camptodactyly
Time frame: 2, 4, 8, and 12 weeks, and 6 months after surgery
Postoperative Complications
Time frame: From surgery through 6 months after surgery
Upper Extremity Function
Time frame: Baseline and 6 months after surgery
Patient or Caregiver Satisfaction
Time frame: 6 months after surgery
Adherence to Nighttime Extension Splint Use
Time frame: From initiation of rehabilitation until 6 months after surgery
Adherence to Rehabilitation Protocol
Time frame: From initiation of rehabilitation until 6 months after surgery
Surgical Outcome According to the Siegert Classification
Time frame: 6 months after surgery
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Sep 2026.
- Background: PubMed 29691077Wall LB, Ezaki M, Goldfarb CA. Camptodactyly Treatment for the Lesser Digits. J Hand Surg Am. 2018 Sep;43(9):874.e1-874.e4. doi: 10.1016/j.jhsa.2018.03.023. Epub 2018 Apr 22.
- Background: PubMed 33319010Morimoto Y, Sogabe Y, Kawabata A, Takamatsu K. Digital artery perforator flap transfer for volar soft tissue defect due to dissociation from joint contracture in camptodactyly. JPRAS Open. 2020 Nov 30;27:48-52. doi: 10.1016/j.jpra.2020.11.009. eCollection 2021 Mar.
- Background: PubMed 36894622Liao W, Wang L, Tang Y, Jiang L, Guo R, Zhuang H, Tang K, Zheng P. Modified radial tongue-shaped flap following stepwise surgical release for Benson type I camptodactyly of the 5th digit. Sci Rep. 2023 Mar 9;13(1):3927. doi: 10.1038/s41598-023-31138-1.
- Background: PubMed 28277466Evans BT, Waters PM, Bae DS. Early Results of Surgical Management of Camptodactyly. J Pediatr Orthop. 2017 Jul/Aug;37(5):e317-e320. doi: 10.1097/BPO.0000000000000967.
- Background: PubMed 29625643Yannascoli SM, Goldfarb CA. Treating Congenital Proximal Interphalangeal Joint Contracture. Hand Clin. 2018 May;34(2):237-249. doi: 10.1016/j.hcl.2017.12.013.
- Look for "camptodactilia" in the field "Título da Pesquisa:" and "moretto" in the "Pesquisador Principal:" filed. This will show the registry of this study.Link provided by the sponsor.
- Individual participant dataSharing planned: No. Individual participant data will not be shared publicly. Given the pediatric population and the small sample size, even de-identified individual-level data may present a risk of participant re-identification.
Related trials for Camptodactyly
RecruitingObservational study
CACP: Study on Camptodactyly - Arthropathy - Coxa Vara - Pericarditis (CACP) Syndrome
Camptodactyly, Arthropathy
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Radial Longitudinal Flap and Full-Thickness Skin Graft in people with Camptodactyly, run by Associação de Assistência a Criança Deficiente at 1 site in Brazil.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 3 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Brazil. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Renato TS Moretto, Hand Surgeon (5511964214000, rmoretto@uol.com.br), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Maintenance of proximal interphalangeal joint extension (time frame: From baseline (preoperative assessment) to 6 months after surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07786701, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Sep 2026.