Large Angle ExotropiaNCT07784842
True Muscle Transplantation Surgery Versus Augmented Semi Hang Back Recession in Large Angle Exotropia: Evaluation of Efficacy and Lateral Gaze Incomitance
A study testing True Muscle Transplantation Surgery and Augmented Semi hang back Recession in people with Large Angle Exotropia, run by Hassnaa Mohamed Abdelhameed Ahmed at 1 site in Egypt.
Trial summary
This a randomized clinical trial comparing True muscle transplantation surgery versus Augmented Semi hang back recession for treatment of large angle exotropia Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Large Angle Exotropia
- What is being tested?
- True Muscle Transplantation Surgery and Augmented Semi hang back Recession
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Mar 2026to Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Who may be able to join
- Patients with large angle exotropia more than 50 prism diopters.
- No previous squint surgery.
Who cannot join
- Patients with severe ocular surface diseases as ocular cicatricial pemphigoid and severe dry eye.
- Severe systemic illness that prevents general anesthesia
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Minya University Hospital - Ophthalmology Department
Minya, Minya Governorate, 61111
About this study
This a randomized clinical trial comparing True muscle transplantation surgery versus Augmented Semi hang back recession for treatment of large angle exotropia
Read the detailed description
large angle exotropia is a challenging to treat surgically .40 patients will be randomized into 2 groups and followed for 6 months to assess alignment and success rate
- Conditions
- Large Angle Exotropia
- Being tested
- True Muscle Transplantation Surgery, Augmented Semi hang back Recession
- Keywords
- exotropia,strabismus,muscle transplantation,augmented recession
- Medical subject headings
- Exotropia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
True Muscle Transplantation SurgeryProcedure or surgery
true Muscle Transplantation surgery for treatment of large angle Exotropia
Augmented Semi hang back RecessionProcedure or surgery
Augmented Semi hang back Recession for treatment of large angle Exotropia
| Study group | Role | What they receive |
|---|---|---|
| True Muscle Transplantation Surgery | Experimental | Patients in this group will undergo True Muscle Transplantation Surgery For treatment of large angle exotropia Receives: Procedure: True Muscle Transplantation Surgery |
| Augmented Semi hang back Recession | Experimental | Patients in this group will undergo Augmented Semi hang back Recession for treatment of large angle exotropia Receives: Procedure: Augmented Semi hang back Recession |
What is being measured
The primary outcome is the main question the study is designed to answer.
Surgical success rate at 6 months
Proportion of patients with ocular alignment within 10 prism diopters of orthotropia measured by prism and alternate cover test
Measured: 6 months post-surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Aug 2026
- Study start1 Mar 2026
- Primary completionOct 2026 (estimated)
- Study completionJan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Large Angle ExotropiaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Patients will be randomly assigned to 1 of 2 surgical intervention arms
- Masking
- None (open label)
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Hassnaa Mohamed Abdelhameed Ahmed
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Hassnaa Mohamed Abdelhameed Ahmed, Minia University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07784842
- Sponsor's protocol ID
- MiniaU-Oph- 2026-EXOT-01
- Status last verified
- Aug 2026
- First submitted
- 20 Aug 2026
- Last updated
- 25 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- True Muscle Transplantation Surgery Versus Augmented Semi Hang Back Recession in Large Angle Exotropia: Evaluation of Efficacy and Lateral Gaze Incomitance
- ClinicalTrials.gov ID
- NCT07784842
- Acronym / sponsor ID
- MiniaU-Oph- 2026-EXOT-01
- Conditions
- Large Angle Exotropia
- Keywords
- exotropia,strabismus,muscle transplantation,augmented recession
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Hassnaa Mohamed Abdelhameed AhmedUniversity, hospital or other
- Study start
- 1 Mar 2026 (actual)
- Primary completion
- Oct 2026 (estimated)
- Study completion
- Jan 2027 (estimated)
- First posted
- 25 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This a randomized clinical trial comparing True muscle transplantation surgery versus Augmented Semi hang back recession for treatment of large angle exotropia
Detailed description
large angle exotropia is a challenging to treat surgically .40 patients will be randomized into 2 groups and followed for 6 months to assess alignment and success rate
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Patients will be randomly assigned to 1 of 2 surgical intervention arms
| Arm | Type | Receives |
|---|---|---|
| True Muscle Transplantation Surgery | Experimental | Procedure: True Muscle Transplantation SurgeryPatients in this group will undergo True Muscle Transplantation Surgery For treatment of large angle exotropia |
| Augmented Semi hang back Recession | Experimental | Procedure: Augmented Semi hang back RecessionPatients in this group will undergo Augmented Semi hang back Recession for treatment of large angle exotropia |
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (2 listed)
- Patients with large angle exotropia more than 50 prism diopters.
- No previous squint surgery.
Key exclusion criteria (2 listed)
- Patients with severe ocular surface diseases as ocular cicatricial pemphigoid and severe dry eye.
- Severe systemic illness that prevents general anesthesia
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| True Muscle Transplantation Surgerytrue Muscle Transplantation surgery for treatment of large angle Exotropia | Procedure or surgery | True Muscle Transplantation Surgery |
| Augmented Semi hang back RecessionAugmented Semi hang back Recession for treatment of large angle Exotropia | Procedure or surgery | Augmented Semi hang back Recession |
Primary outcome
Surgical success rate at 6 months
Time frame: 6 months post-surgery
Proportion of patients with ocular alignment within 10 prism diopters of orthotropia measured by prism and alternate cover test
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Aug 2026.
Related trials for Large Angle Exotropia
Recruiting
Comparative Study of Muscle Transplantation Versus Y Splitting Recession Technique in Treatment of Large Angle Exotropia
Exotropia
Not yet recruiting
A Comparative Study Between Three Surgical Techniques in Large Angle Exotropia
Exotropia Equal or More Than 50 Prism Diopter
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing True Muscle Transplantation Surgery and Augmented Semi hang back Recession in people with Large Angle Exotropia, run by Hassnaa Mohamed Abdelhameed Ahmed at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 25 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Hassnaa Mohamed Abdelhameed, Assistant lecturer (+201158861290, hasnaa.abdelhamid@mu.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Surgical success rate at 6 months (time frame: 6 months post-surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Aug 2026.