Dental Plaque AccumulationINDISNCT07784803
In Situ Evaluation of Plaque Accumulation on Innovative Nanostructured Metal Implant Surfaces
A study testing Maxillary tray in people with Dental Plaque Accumulation, run by Malmö University.
Trial summary
Participants will get a customized maxillary tray carrying 2 pairs of metal disks with a nanostructured surface. They will wear the trays continuously for 72 hours except when eating, drinking or brushing their teeth. Plaque accumulation on the discs will be subsequently quantified. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Dental Plaque Accumulation
- What is being tested?
- Maxillary tray
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 20 participants
- Where
- No sites listed yet
- Study dates
- 31 Aug 2026to 31 Aug 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Periodontally healthy
Who cannot join
- Periodontitis patient
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Participants will get a customized maxillary tray carrying 2 pairs of metal disks with a nanostructured surface. They will wear the trays continuously for 72 hours except when eating, drinking or brushing their teeth. Plaque accumulation on the discs will be subsequently quantified.
- Conditions
- Dental Plaque Accumulation
- Being tested
- Maxillary tray
- Keywords
- Dental plaque, Nano-structured, Dental implant, Surface modification
- Medical subject headings
- Dental Plaque
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Maxillary trayDevice
Maxillary tray with 4 metal disks with various surface modifications
| Study group | Role | What they receive |
|---|---|---|
| Study Arm | Experimental | Study participants wearing the tray Receives: Device: Maxillary tray |
What is being measured
The primary outcome is the main question the study is designed to answer.
Dental Plaque Accumulation
Amount of dental plaque accumulation will be assessed in the laboratory
Measured: 72 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Aug 2026
- Study start31 Aug 2026 (estimated)
- Primary completion15 Jun 2027 (estimated)
- Study completion31 Aug 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Dental Plaque AccumulationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 20 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Malmö University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Andreas Stavropoulos, Malmö University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07784803
- Sponsor's protocol ID
- 2024-02157
- Acronym
- INDIS
- Status last verified
- Aug 2026
- First submitted
- 20 Aug 2026
- Last updated
- 25 Aug 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- In Situ Evaluation of Plaque Accumulation on Innovative Nanostructured Metal Implant Surfaces
- ClinicalTrials.gov ID
- NCT07784803
- Acronym / sponsor ID
- INDIS / 2024-02157
- Conditions
- Dental Plaque Accumulation
- Keywords
- Dental plaque, Nano-structured, Dental implant, Surface modification
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 20 participants (estimated)
- Lead sponsor
- Malmö UniversityUniversity, hospital or other
- Study start
- 31 Aug 2026 (estimated)
- Primary completion
- 15 Jun 2027 (estimated)
- Study completion
- 31 Aug 2027 (estimated)
- First posted
- 25 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Participants will get a customized maxillary tray carrying 2 pairs of metal disks with a nanostructured surface. They will wear the trays continuously for 72 hours except when eating, drinking or brushing their teeth. Plaque accumulation on the discs will be subsequently quantified.
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Study Arm | Experimental | Device: Maxillary trayStudy participants wearing the tray |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Periodontally healthy
Key exclusion criteria (1 listed)
- Periodontitis patient
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Maxillary trayMaxillary tray with 4 metal disks with various surface modifications | Device | Study Arm |
Primary outcome
Dental Plaque Accumulation
Time frame: 72 hours
Amount of dental plaque accumulation will be assessed in the laboratory
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Aug 2026.
- Individual participant dataSharing planned: No
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Probiotic-Based Versus Ethyl Lauroyl Arginate-Containing Mouthwashes on Streptococcus Mutans Counts, Dental Plaque Accumulation, and Salivary pH in a Group of Egyptian School Children
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Comparing the Antiplaque Effects of Novel Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Maxillary tray in people with Dental Plaque Accumulation, run by Malmö University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 25 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Andreas Stavropoulos Professor, PhD, odont dr (+46 40 6658066, andreas.stavropoulos@mau.se), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Dental Plaque Accumulation (time frame: 72 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Aug 2026.