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Myofascial Pain SyndromeNCT07770308

Comparison of the Efficacy of Kinesio Taping and TENS Therapy in Patients With Cervical Myofascial Pain Syndrome

A study testing home-based exercises, TENS and kinesiology taping in people with Myofascial Pain Syndrome, run by Bakirkoy Dr. Sadi Konuk Research and Training Hospital at 1 site in Turkey (Türkiye).

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

Cervical MPS is a condition of pain, weakness and loss of function caused by trigger points located in the tense bands in the muscles in the neck and upper back. Pharmacological and non-pharmacological treatments are used in the treatment of MPS. Read more about this study

Who is it for?
Ages 18 to 65 years
Conditions the study is for
Myofascial Pain Syndrome
What is being tested?
home-based exercises, TENS and kinesiology taping
Type of treatment
Medical device
Could I receive a placebo?
No, everyone receives an active treatment
How many people
45 participants
Where
1 siteTurkey (Türkiye)
Study dates
1 Dec 2023to 15 Apr 2024
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 65 years
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Being between the ages of 18-65 and diagnosed with cervical MAS according to the major and minor diagnostic criteria defined by Travel and Simons.

Who cannot join

  • Those diagnosed with myofascial syndrome and receiving medical treatment and physical therapy
  • Those diagnosed with myofascial syndrome and taking an exercise program
  • Those diagnosed with fibromyalgia syndrome
  • Skin disease and edema in the area to be applied
  • Kinesiology tape allergy
  • Neurological diseases (Epilepsy, stroke, upper motor neuron lesions)
Show all 12Show fewer
  • People using pacemakers
  • Hypertension and diabetes that cannot be controlled with medication
  • Any fracture pathology involving the upper extremity and cervical region,
  • Other cervical pathologies that may cause neck pain other than MAS
  • Pregnancy
  • Cognitive dysfunction and poor cooperation

Trial locations and contacts

1 site in 1 country.

Turkey (Türkiye)1 site
  • Bakırkoy Dr. Sadi Konuk Hospital

    Istanbul, Bakırköy, 34147

Other trials in Turkey (Türkiye)

About this study

Official title: Comparison of the Efficacy of Kinesio Taping and TENS Therapy Using Ultrasound Elastography in Patients With Cervical Myofascial Pain Syndrome: Randomized Controlled Trial

Cervical MPS is a condition of pain, weakness and loss of function caused by trigger points located in the tense bands in the muscles in the neck and upper back. Pharmacological and non-pharmacological treatments are used in the treatment of MPS. Although different treatment methods are used for MPS today, there is no proven treatment method to be superior to others. This study aimed to compare the effectiveness of exercise therapy, kinesiology taping and TENS therapy on pain, muscle strength and functional status in patients with cervical myofascial pain syndrome.

Read the detailed description

Myofascial pain syndrome (MPS) is a non-inflammatory musculoskeletal disease characterized by the presence of hyperirritable palpable trigger points accompanied by pain and muscle stiffness. Main signs and symptoms of MPS; pain, spasm, decrease in joint range of motion, difficulty in daily living activities and deterioration in quality of life. Pharmacological and non-pharmacological treatments are used in the treatment of MPS. Among non-pharmacological treatments, postural and mechanical modifications, exercises, stress reduction, electrotherapy methods, regional cold and hot application, local anesthetic injections, kinesiological taping, acupuncture and dry needling can be preferred. This study aimed to compare the effectiveness of exercise therapy, kinesiology taping and TENS therapy on pain, muscle strength and functional status in patients with cervical myofascial pain syndrome.

Being tested
home-based exercises, TENS, kinesiology taping
Keywords
myofascial pain syndrome, TENS therapy, kinesiology taping, exercise
Medical subject headings
Myofascial Pain Syndromes, Motor Activity

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • home-based exercisesOther

    Exercise therapy is one of the most commonly used conservative treatment methods in the cervical MAS treatment protocol. Patients in the first group will be given trunk stabilization training, scapular adductor muscle strengthening, cervical posterior tilt, and stretching exercises for neck rotators, scalene muscles, levator scapula muscle, upper trapezius muscle, posterior cervical and suboccipital muscles. Among these exercises, it will be said that the strengthening exercises should be done in 2 sets of 30 repetitions a day, and the stretching exercises should be done in 2 sets of 10 repetitions. These exercises will be given as a home program and you will be asked to practice them every day for 4 weeks.

  • TENSDevice

    TENS is an electric current applied with superficial electrodes placed on the skin and used to relieve pain. Conventional (Traditional) TENS is the most commonly used type. It affects the transmission of pain on the gate control theory by affecting the thick, myelinated, afferent A alpha and beta fibers. The effect of conventional TENS begins in 30 minutes and disappears within approximately 2 hours after treatment is stopped. TENS will be applied to the patients in the second group with a Bio-Stim brand VH-1000 model TENS device in the form of symmetrical, biphasic quadrilateral pulses for 100 msec. Frequency is 60 Hertz (Hz), intensity will be adjusted according to the patient's perception of paresthesia. The negative electrode will be placed on the active trigger point on the upper trapezius muscle and the positive electrode on the acromial tendon. The total duration of the application will be 20 minutes and 1 session will be applied every day for two weeks, a total of 10 sessions.

  • kinesiology tapingDevice

    Kinesiology taping has a wide range of indications, especially in the musculoskeletal system. It is used to protect against tissue damage in the musculoskeletal system and to treat existing injuries, injuries, pain and dysfunctions. Patients who receive kinesiology taping treatment will receive treatment six times in total for three weeks, with 3-day intervals. After the patient is allowed to sit comfortably on the chair, taping will be performed between the acromioclavicular joint and the C7 spinous process using the upper trapezius inhibition technique. In addition, a small kinesiological taping test will be applied to the patient's volar forearm as a rapid allergy screening test to prevent any dermatological allergic reaction.

Study groups in NCT07770308
Study groupRoleWhat they receive
Group One (Group of Exercise)Active comparatorPatients in the first group will be given trunk stabilization training, scapular adductor muscle strengthening, cervical posterior tilt, and stretching exercises for neck rotators, scalene muscles, levator scapula muscle, upper trapezius muscle, posterior cervical and suboccipital muscles. Among these exercises, it will be said that the strengthening exercises should be done in 2 sets of 30 repetitions a day, and the stretching exercises should be done in 2 sets of 10 repetitions. These exercises will be given as a home program and you will be asked to practice them every day for 4 weeks.
Receives: Other: home-based exercises
Group Two ( Group of TENS Therapy and Exercise)Active comparatorTENS is an electric current applied with superficial electrodes placed on the skin and used to relieve pain. It is also used in the treatment of cervical MAS. It can be applied together with other treatment methods. It has a pain relieving effect. The total duration of the application will be 20 minutes and 1 session will be applied every day for two weeks, a total of 10 sessions. In addition to this treatment, patients will also be given exercise therapy.
Receives: Other: home-based exercises; Device: TENS
Group Three (Group of Kinesiology Taping and Exercise)Active comparatorKinesiology taping is one of the treatment methods used in various musculoskeletal system diseases. It does not restrict daily activities. It supports the person's movement and ensures that muscle functions return to normal. Kinesiology tape is made of 100% cotton and has an elastic structure that can extend up to 30-40% of its length. The tape is water resistant and can stay on the skin for about 1 week. In this study, kinesiology taping will be applied twice a week for three weeks. In addition to this treatment, patients will also be given exercise therapy.
Receives: Other: home-based exercises; Device: kinesiology taping

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. VAS (Visual Analogue Scale)

    Pain intensity was assessed using the Visual Analog Scale. Participants rated their pain separately at rest and during activity on a 10-cm horizontal line ranging from 0 to 10, where 0 represents "no pain" and 10 represents "the worst imaginable pain." Higher scores indicate greater pain intensity and therefore a worse outcome.

    Measured: Baseline, immediately after treatment, and 4 weeks after treatment completion

  2. Ultrasound Elastography

    The last step of the high development rate in ultrasonography technology is ultrasound elastography (UE). UE is a technological advance that can directly measure the mechanical properties of tissue, including muscle stiffness. Elasticity; It is the ability of a tissue to be deformed by an external force and to return to its previous shape and size when this force is removed.

    Measured: Baseline, immediately after treatment, and 4 weeks after treatment completion

Secondary outcomes (2)
  1. Range of Motion (ROM)

    Cervical ROM, flexion, extension, right rotation, left rotation, right lateral flexion, left lateral flexion measurements during active movement will be measured with a goniometer device and recorded in degrees.

    Measured: Baseline, immediately after treatment, and 4 weeks after treatment completion

  2. Neck Disability Index (NDI)

    Neck Disability Index is a scale consisting of 10 questions and used to evaluate how and to what extent neck pain affects the patient's daily life activities. Scale; It includes pain severity, self-care, lifting, reading, headache, concentration, driving, sleep and social activity parameters. Patients were asked to mark the one that was most suitable for them among the 6 options given for each parameter. Each topic is scored from 0 (no disability) to 5 (complete disability). The total score ranges from 0 (no disability) to 50 (total disability). After the total score is obtained, the value calculated according to the formulation is finalized as % deficiency. As the score increases, disability increases, and as the score decreases, disability decreases.

    Measured: Baseline, immediately after treatment, and 4 weeks after treatment completion

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted18 Aug 2026
  2. Study start1 Dec 2023
  3. Primary completion15 Mar 2024
  4. Study completion15 Apr 2024

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Investigator
Enrolment
45 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07770308
Sponsor's protocol ID
2022/369
Status last verified
Aug 2026
First submitted
8 Aug 2026
Last updated
18 Aug 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No: Results of the study will be written as a manuscript. In Turkey, we do not have a system sharing data to other researchers.

Publications

  • Hong CZ. Treatment of myofascial pain syndrome. Curr Pain Headache Rep. 2006 Oct;10(5):345-9. doi: 10.1007/s11916-006-0058-3.

    PubMed 16945250
  • De Meulemeester KE, Castelein B, Coppieters I, Barbe T, Cools A, Cagnie B. Comparing Trigger Point Dry Needling and Manual Pressure Technique for the Management of Myofascial Neck/Shoulder Pain: A Randomized Clinical Trial. J Manipulative Physiol Ther. 2017 Jan;40(1):11-20. doi: 10.1016/j.jmpt.2016.10.008.

    PubMed 28017188
  • Borg-Stein J, Iaccarino MA. Myofascial pain syndrome treatments. Phys Med Rehabil Clin N Am. 2014 May;25(2):357-74. doi: 10.1016/j.pmr.2014.01.012. Epub 2014 Mar 17.

    PubMed 24787338
  • Ziaeifar M, Arab AM, Mosallanezhad Z, Nourbakhsh MR. Dry needling versus trigger point compression of the upper trapezius: a randomized clinical trial with two-week and three-month follow-up. J Man Manip Ther. 2019 Jul;27(3):152-161. doi: 10.1080/10669817.2018.1530421. Epub 2018 Oct 15.

    PubMed 30935341
  • Saxena A, Chansoria M, Tomar G, Kumar A. Myofascial pain syndrome: an overview. J Pain Palliat Care Pharmacother. 2015 Mar;29(1):16-21. doi: 10.3109/15360288.2014.997853. Epub 2015 Jan 5.

    PubMed 25558924
  • Borg-Stein J, Simons DG. Focused review: myofascial pain. Arch Phys Med Rehabil. 2002 Mar;83(3 Suppl 1):S40-7, S48-9. doi: 10.1053/apmr.2002.32155.

    PubMed 11973695
  • Ardic F, Sarhus M, Topuz O. Comparison of two different techniques of electrotherapy on myofascial pain. J Back Musculoskelet Rehabil. 2002 Jan 1;16(1):11-6. doi: 10.3233/bmr-2002-16103.

    PubMed 22387359
  • Graff-Radford SB, Reeves JL, Baker RL, Chiu D. Effects of transcutaneous electrical nerve stimulation on myofascial pain and trigger point sensitivity. Pain. 1989 Apr;37(1):1-5. doi: 10.1016/0304-3959(89)90146-2.

    PubMed 2786179
  • Kalron A, Bar-Sela S. A systematic review of the effectiveness of Kinesio Taping--fact or fashion? Eur J Phys Rehabil Med. 2013 Oct;49(5):699-709. Epub 2013 Apr 5.

    PubMed 23558699
  • Paoloni M, Bernetti A, Fratocchi G, Mangone M, Parrinello L, Del Pilar Cooper M, Sesto L, Di Sante L, Santilli V. Kinesio Taping applied to lumbar muscles influences clinical and electromyographic characteristics in chronic low back pain patients. Eur J Phys Rehabil Med. 2011 Jun;47(2):237-44. Epub 2011 Mar 24.

    PubMed 21430611
  • Kaya E, Zinnuroglu M, Tugcu I. Kinesio taping compared to physical therapy modalities for the treatment of shoulder impingement syndrome. Clin Rheumatol. 2011 Feb;30(2):201-7. doi: 10.1007/s10067-010-1475-6. Epub 2010 Apr 30.

    PubMed 20443039
  • Gennisson JL, Deffieux T, Fink M, Tanter M. Ultrasound elastography: principles and techniques. Diagn Interv Imaging. 2013 May;94(5):487-95. doi: 10.1016/j.diii.2013.01.022. Epub 2013 Apr 22.

    PubMed 23619292
  • Domenichini R, Pialat JB, Podda A, Aubry S. Ultrasound elastography in tendon pathology: state of the art. Skeletal Radiol. 2017 Dec;46(12):1643-1655. doi: 10.1007/s00256-017-2726-2. Epub 2017 Aug 1.

    PubMed 28765991
  • Vernon H. The Neck Disability Index: state-of-the-art, 1991-2008. J Manipulative Physiol Ther. 2008 Sep;31(7):491-502. doi: 10.1016/j.jmpt.2008.08.006.

    PubMed 18803999

Questions about this trial

What is this clinical trial studying?

A study testing home-based exercises, TENS and kinesiology taping in people with Myofascial Pain Syndrome, run by Bakirkoy Dr. Sadi Konuk Research and Training Hospital at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 18 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

VAS (Visual Analogue Scale) (time frame: Baseline, immediately after treatment, and 4 weeks after treatment completion). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07770308, which also lists 14 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Aug 2026; AzTrials last refreshed its copy on 8 Nov 2026.

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