Medicinal Chemistry Teaching ReformNCT07767734
Comparison of the BOPPPS Model and Traditional Instructional Method in Medicinal Chemistry Education
A study testing BOPPPS six-stage teaching intervention and Conventional lecture-based teaching intervention in people with Medicinal Chemistry Teaching Reform and BOPPPS Teaching Model, run by Jiangsu Medical College at 1 site in China.
Trial summary
This study aims to compare the teaching effect of the BOPPPS teaching model and the traditional lecture-based teaching method in Medicinal Chemistry courses for pharmacy students. Two groups of students receiving different teaching strategies will be included in this retrospective controlled study. Read more about this study
- Who is it for?
- Ages 17 to 24 yearsHealthy volunteers can take part
- Conditions the study is for
- Medicinal Chemistry Teaching Reform, BOPPPS Teaching Model, Traditional Teaching Methods
- What is being tested?
- BOPPPS six-stage teaching intervention and Conventional lecture-based teaching intervention
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteChina
- Study dates
- 15 Sep 2025to 8 Jan 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 17 to 24 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Full-time pharmacy students without previous Medicinal Chemistry learning experience
- Complete all academic assessments and anonymous questionnaire surveys
Who cannot join
- Classroom attendance rate less than 80%
- Students who are unwilling to provide relevant data for this educational study or miss the final exam
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparison of the BOPPPS Model and Traditional Instructional Method in Medicinal Chemistry Education for Pharmacy Students
This study aims to compare the teaching effect of the BOPPPS teaching model and the traditional lecture-based teaching method in Medicinal Chemistry courses for pharmacy students. Two groups of students receiving different teaching strategies will be included in this retrospective controlled study. The primary evaluation indicators include students' final examination scores, and secondary indicators cover classroom learning engagement and student satisfaction questionnaires. The overall objective is to explore whether the BOPPPS model can improve students' learning performance and learning experience in Medicinal Chemistry teaching. No human clinical intervention or invasive testing is involved in this educational research.
Read the detailed description
This educational controlled study focuses on the teaching reform of Medicinal Chemistry, a core compulsory course for pharmacy majors in higher vocational colleges. Traditional lecture-centered teaching is widely adopted in vocational pharmacy teaching, which often leads to insufficient student participation, weak initiative in classroom interaction, and unsatisfactory learning efficiency for complex pharmaceutical chemical structures and synthetic reactions.The BOPPPS teaching model divides each class into six standardized links: Bridge-in, Objectives, Pre-assessment, Participatory learning, Post-assessment, Summary. This student-centered teaching design strengthens classroom interaction and targeted detection of learning effects. At present, there is limited comparative research on the application of this model in Medicinal Chemistry teaching for vocational pharmacy students.This retrospective controlled research collects historical teaching data of two student groups receiving different teaching modes. The research intends to systematically analyze the differences in learning outcomes between the two teaching strategies, so as to provide practical teaching reform references for Medicinal Chemistry courses in vocational pharmacy education. This study only adopts routine classroom teaching and anonymous questionnaire surveys, without any clinical medical intervention, blood sampling or physical examination on participants. All student data are anonymized to protect personal privacy. Article 32 of the Notice on Printing and Distributing the Measures for Ethical Review of Life Science and Medical Research Involving Humans, jointly issued by the National Health Commission of China, the Ministry of Education, the Ministry of Science and Technology, and the National Administration of Traditional Chinese Medicine, stipulates that "Life science and medical research involving humans that uses human information, data or biological samples may be exempt from ethical review if such research falls under the circumstances specified below, causes no physical harm to human participants, and does not involve sensitive personal information or commercial interests." As a study focusing on teaching effectiveness, the present research qualifies for an exemption from ethical review pursuant to this provision.
- Being tested
- BOPPPS six-stage teaching intervention, Conventional lecture-based teaching intervention
- Keywords
- Medicinal Chemistry, BOPPPS model, Pharmacy teaching, Teaching comparison
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
BOPPPS six-stage teaching interventionOther
Medicinal Chemistry teaching based on BOPPPS model, consisting of Bridge-in, Objectives, Pre-assessment, Participatory learning, Post-assessment and Summary sessions with abundant classroom interaction.
Conventional lecture-based teaching interventionOther
Traditional teacher-centered lecture teaching for Medicinal Chemistry, mainly knowledge explanation, without segmented pre-assessment and post-assessment arrangements.
| Study group | Role | What they receive |
|---|---|---|
| Experimental Group (BOPPPS Teaching Model) | Experimental | Pharmacy students receive Medicinal Chemistry courses adopting the complete six-link BOPPPS teaching design, including Bridge-in, Objectives, Pre-assessment, Participatory learning, Post-assessment and Summary. Interactive classroom activities and in-class tests are arranged in each lesson. Receives: Other: BOPPPS six-stage teaching intervention |
| Control Group (Traditional Lecture Teaching) | Active comparator | Pharmacy students receive teacher-centered traditional lecture-based Medicinal Chemistry teaching. The teacher explains knowledge points directly, with few classroom interactive sessions. Receives: Other: Conventional lecture-based teaching intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Final examination scores of Medicinal Chemistry
Final exam scores to evaluate students' mastery of professional knowledge of Medicinal Chemistry. Scores range from 0 to 100. Higher scores indicate better academic performance.
Measured: At the completion of the teaching intervention, up to 1 week
Secondary outcomes (1)
Student teaching satisfaction score
Score from an anonymous questionnaire evaluating students' satisfaction with the classroom teaching model. The total score ranges from 1 to 5. Higher scores indicate higher satisfaction.
Measured: At the completion of the teaching intervention, up to 1 week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Aug 2026
- Study start15 Sep 2025
- Primary completion6 Jan 2026
- Study completion8 Jan 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Medicinal Chemistry Teaching ReformStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Two parallel groups of pharmacy students receive different teaching interventions respectively. The experimental group adopts the BOPPPS teaching model for Medicinal Chemistry courses, while the control group receives conventional lecture-based teaching. No cross-over or alternating intervention is conducted between the two groups throughout the study period. All student data are collected retrospectively after the completion of teaching.
- Masking
- None (open label)
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Jiangsu Medical College
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Liang Qi, Jiangsu Medical College
- Investigators
- Liang Qi, PhD, Principal investigator, Jiangsu Medical College
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07767734
- Sponsor's protocol ID
- JiangsuMC-20260806
- Other IDs
- 2025JGYB272
- Status last verified
- Aug 2026
- First submitted
- 6 Aug 2026
- Last updated
- 17 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified individual participant-level data supporting this study, together with a complete data dictionary, will be accessible to qualified external researchers upon reasonable written request after the primary manuscript is published. Data release is conditional on institutional and regulatory privacy authorization. All formal data access requests should be submitted to the corresponding author for evaluation and review. No identifiable personal information will be included in shared datasets to protect student privacy.
Study at a glance
From the registry record, last updated by the sponsor on 17 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the BOPPPS Model and Traditional Instructional Method in Medicinal Chemistry Education for Pharmacy Students
- ClinicalTrials.gov ID
- NCT07767734
- Acronym / sponsor ID
- JiangsuMC-20260806
- Keywords
- Medicinal Chemistry, BOPPPS model, Pharmacy teaching, Teaching comparison
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Jiangsu Medical CollegeUniversity, hospital or other
- Study start
- 15 Sep 2025 (actual)
- Primary completion
- 6 Jan 2026 (actual)
- Study completion
- 8 Jan 2026 (actual)
- First posted
- 17 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to compare the teaching effect of the BOPPPS teaching model and the traditional lecture-based teaching method in Medicinal Chemistry courses for pharmacy students. Two groups of students receiving different teaching strategies will be included in this retrospective controlled study. The primary evaluation indicators include students' final examination scores, and secondary indicators cover classroom learning engagement and student satisfaction questionnaires. The overall objective is to explore whether the BOPPPS model can improve students' learning performance and learning experience in Medicinal Chemistry teaching. No human clinical intervention or invasive testing is involved in this educational research.
Detailed description
This educational controlled study focuses on the teaching reform of Medicinal Chemistry, a core compulsory course for pharmacy majors in higher vocational colleges. Traditional lecture-centered teaching is widely adopted in vocational pharmacy teaching, which often leads to insufficient student participation, weak initiative in classroom interaction, and unsatisfactory learning efficiency for complex pharmaceutical chemical structures and synthetic reactions.The BOPPPS teaching model divides each class into six standardized links: Bridge-in, Objectives, Pre-assessment, Participatory learning, Post-assessment, Summary. This student-centered teaching design strengthens classroom interaction and targeted detection of learning effects. At present, there is limited comparative research on the application of this model in Medicinal Chemistry teaching for vocational pharmacy students.This retrospective controlled research collects historical teaching data of two student groups receiving different teaching modes. The research intends to systematically analyze the differences in learning outcomes between the two teaching strategies, so as to provide practical teaching reform references for Medicinal Chemistry courses in vocational pharmacy education. This study only adopts routine classroom teaching and anonymous questionnaire surveys, without any clinical medical intervention, blood sampling or physical examination on participants. All student data are anonymized to protect personal privacy. Article 32 of the Notice on Printing and Distributing the Measures for Ethical Review of Life Science and Medical Research Involving Humans, jointly issued by the National Health Commission of China, the Ministry of Education, the Ministry of Science and Technology, and the National Administration of Traditional Chinese Medicine, stipulates that "Life science and medical research involving humans that uses human information, data or biological samples may be exempt from ethical review if such research falls under the circumstances specified below, causes no physical harm to human participants, and does not involve sensitive personal information or commercial interests." As a study focusing on teaching effectiveness, the present research qualifies for an exemption from ethical review pursuant to this provision.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Two parallel groups of pharmacy students receive different teaching interventions respectively. The experimental group adopts the BOPPPS teaching model for Medicinal Chemistry courses, while the control group receives conventional lecture-based teaching. No cross-over or alternating intervention is conducted between the two groups throughout the study period. All student data are collected retrospectively after the completion of teaching.
| Arm | Type | Receives |
|---|---|---|
| Experimental Group (BOPPPS Teaching Model) | Experimental | Other: BOPPPS six-stage teaching interventionPharmacy students receive Medicinal Chemistry courses adopting the complete six-link BOPPPS teaching design, including Bridge-in, Objectives, Pre-assessment, Participatory learning, Post-assessment and Summary. Interactive classroom activities and in-class tests are arranged in each lesson. |
| Control Group (Traditional Lecture Teaching) | Active comparator | Other: Conventional lecture-based teaching interventionPharmacy students receive teacher-centered traditional lecture-based Medicinal Chemistry teaching. The teacher explains knowledge points directly, with few classroom interactive sessions. |
Who may qualify
- Ages
- 17 to 24 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (2 listed)
- Full-time pharmacy students without previous Medicinal Chemistry learning experience
- Complete all academic assessments and anonymous questionnaire surveys
Key exclusion criteria (2 listed)
- Classroom attendance rate less than 80%
- Students who are unwilling to provide relevant data for this educational study or miss the final exam
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| BOPPPS six-stage teaching interventionMedicinal Chemistry teaching based on BOPPPS model, consisting of Bridge-in, Objectives, Pre-assessment, Participatory learning, Post-assessment and Summary sessions with abundant classroom interaction. | Other | Experimental Group (BOPPPS Teaching Model) |
| Conventional lecture-based teaching interventionTraditional teacher-centered lecture teaching for Medicinal Chemistry, mainly knowledge explanation, without segmented pre-assessment and post-assessment arrangements. | Other | Control Group (Traditional Lecture Teaching) |
Primary outcome
Final examination scores of Medicinal Chemistry
Time frame: At the completion of the teaching intervention, up to 1 week
Final exam scores to evaluate students' mastery of professional knowledge of Medicinal Chemistry. Scores range from 0 to 100. Higher scores indicate better academic performance.
1 secondary outcome
Student teaching satisfaction score
Time frame: At the completion of the teaching intervention, up to 1 week
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Aug 2026.
- Individual participant dataSharing planned: Yes. De-identified individual participant-level data supporting this study, together with a complete data dictionary, will be accessible to qualified external researchers upon reasonable written request after the primary manuscript is published. Data release is conditional on institutional and regulatory privacy authorization. All formal data access requests should be submitted to the corresponding author for evaluation and review. No identifiable personal information will be included in shared datasets to protect student privacy.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Liang Qi, PhD principal investigator
Jiangsu Medical College
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing BOPPPS six-stage teaching intervention and Conventional lecture-based teaching intervention in people with Medicinal Chemistry Teaching Reform and BOPPPS Teaching Model, run by Jiangsu Medical College at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Final examination scores of Medicinal Chemistry (time frame: At the completion of the teaching intervention, up to 1 week). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Aug 2026.