Acetabular FracturesNCT07765095
Pericapsular Nerve Group (PENG) Block on Postoperative Pain Management After Acetabular Fracture Fixation
A study testing Pericapsular nerve group (PENG) block in people with Acetabular Fractures, run by University of Puerto Rico at 1 site in Puerto Rico.
Trial summary
The goal of this clinical trial is to find out whether a Pericapsular Nerve Group (PENG) block, a type of nerve block used to control pain, can reduce pain after surgery in adults with an acetabular (hip socket) fracture who are undergoing surgical repair. The study will also evaluate the safety of the PENG block. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Acetabular Fractures
- What is being tested?
- Pericapsular nerve group (PENG) block
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 56 participants
- Where
- 1 sitePuerto Rico
- Study dates
- 8 Sep 2025to 30 Mar 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patient age 18 years or older
- Acetabular Fracture amenable to surgery through the Kocher-Langenbeck approach
- Full weight-bearing capacity prior to the trauma
- Providing written informed consent
Who cannot join
- Age less than 18 years old
- Fracture pattern not amenable to surgery through Kocher-Langenbeck approach
- Lower extremity fracture ipsilateral to the acetabular fracture
- Any traumatic injury that requires surgical management by other surgical specialty
- Bilateral Acetabular Fractures
- Limited weight bearing capacity prior to the trauma
Show all 12Show fewer
- Procedure performed under any anesthesia other than GETA
- Chronic opioid use
- History of Substance Abuse
- Allergies or history of adverse reactions to any of the drugs used in the
- Mental Disability
- History of Psychiatric disorders
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Puerto Rico1 site, 1 recruiting
- Recruiting
Puerto Rico Medical Center
San Juan, 00935
Luis Lojo-Sojo, MD, 787773535, luis.lojo@upr.edu
Luis Lojo Sojo, MD
About this study
Official title: Efficacy of Pericapsular Nerve Group (PENG) Block on Postoperative Pain Management After Acetabular Fracture Fixation: A Randomized Controlled Trial
The goal of this clinical trial is to find out whether a Pericapsular Nerve Group (PENG) block, a type of nerve block used to control pain, can reduce pain after surgery in adults with an acetabular (hip socket) fracture who are undergoing surgical repair. The study will also evaluate the safety of the PENG block.
The main questions this study aims to answer are:
Read more
Does a PENG block reduce pain after surgery? Does a PENG block reduce the need for opioid pain medications after surgery? Are there any side effects or complications related to the PENG block? Researchers will compare patients who receive a PENG block with patients who do not receive a PENG block to determine whether the block improves pain control after surgery.
Participants will:
Be randomly assigned to receive either a PENG block or no PENG block before surgery while under general anesthesia.
Undergo surgery to repair their acetabular fracture. Receive the same standard pain medications after surgery. Be asked to rate their pain at several time points after surgery using a standard pain scale.
Have their use of pain medications, recovery, and any side effects recorded during their hospital stay and follow-up.
- Conditions
- Acetabular Fractures
- Being tested
- Pericapsular nerve group (PENG) block
- Keywords
- Acetabular Fractures, Pain Management, Pericapsular Nerve Group (PENG), Open Reduction and Internal Fixation (ORIF), Regional Block
- Medical subject headings
- Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Pericapsular nerve group (PENG) blockProcedure or surgery
PENG Block is a regional block technique well documented in the literature for certain orthopedic injuries and interventions. However, the efficacy of this intervention on acetabular fracture fixation has not been well studied or addressed in previous literature.
| Study group | Role | What they receive |
|---|---|---|
| PENG Block Group | Experimental | This group includes participants who will receive the pericapsular nerve group (PENG) block after surgical intervention. Receives: Procedure: Pericapsular nerve group (PENG) block |
| NO PENG Block Group | No intervention | This group includes participants who will not receive the pericapsular nerve group (PENG) block after surgical intervention and will be considered our control group. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Numeric Pain Rating Scale (NPRS)
The NPRS is an 11-point scale scored from 0-10, with " 0 " representing no pain and "10" being the most intense pain experienced. Patients verbally select a value that is most in line with the intensity of pain that they have experienced at each time point under evaluation.
Measured: From surgery to 36 hours after surgery (12 hour Intervals)
Secondary outcomes (2)
Morphine Miligram Equivalent (MME)
MME is the total amount of an opioid drug converted to an equivalent strength of oral morphine. This measure is used to track the consumption of opioids in a standardized, uniform way.
Measured: From surgery to 36 hours after surgery (12 hour Intervals)
Postoperative and Block Associated Complications
Inpatient complications are unforeseen medical issues that arise during a hospital stay, potentially extending recovery time or requiring additional treatment.
Measured: From surgery to 36 hours after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Aug 2026
- Study start8 Sep 2025
- Primary completion30 Jan 2027 (estimated)
- Study completion30 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Acetabular FracturesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Prospective Doble-Blinded Randomized Controlled Trial
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 56 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Puerto Rico
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Luis Lojo Sojo, MD, Principal investigator, University of Puerto Rico
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07765095
- Sponsor's protocol ID
- 2406241594
- Status last verified
- Aug 2026
- First submitted
- 6 Aug 2026
- Last updated
- 23 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Data will be stored in an encrypted digital file and made available for file sharing upon a valid request.
Study at a glance
From the registry record, last updated by the sponsor on 23 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Efficacy of Pericapsular Nerve Group (PENG) Block on Postoperative Pain Management After Acetabular Fracture Fixation: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07765095
- Acronym / sponsor ID
- 2406241594
- Conditions
- Acetabular Fractures
- Keywords
- Acetabular Fractures, Pain Management, Pericapsular Nerve Group (PENG), Open Reduction and Internal Fixation (ORIF), Regional Block
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 56 participants (estimated)
- Lead sponsor
- University of Puerto RicoUniversity, hospital or other
- Study start
- 8 Sep 2025 (actual)
- Primary completion
- 30 Jan 2027 (estimated)
- Study completion
- 30 Mar 2027 (estimated)
- First posted
- 14 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to find out whether a Pericapsular Nerve Group (PENG) block, a type of nerve block used to control pain, can reduce pain after surgery in adults with an acetabular (hip socket) fracture who are undergoing surgical repair. The study will also evaluate the safety of the PENG block.
The main questions this study aims to answer are:
Does a PENG block reduce pain after surgery? Does a PENG block reduce the need for opioid pain medications after surgery? Are there any side effects or complications related to the PENG block? Researchers will compare patients who receive a PENG block with patients who do not receive a PENG block to determine whether the block improves pain control after surgery.
Participants will:
Be randomly assigned to receive either a PENG block or no PENG block before surgery while under general anesthesia.
Undergo surgery to repair their acetabular fracture. Receive the same standard pain medications after surgery. Be asked to rate their pain at several time points after surgery using a standard pain scale.
Have their use of pain medications, recovery, and any side effects recorded during their hospital stay and follow-up.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
- Model description
- Prospective Doble-Blinded Randomized Controlled Trial
| Arm | Type | Receives |
|---|---|---|
| PENG Block Group | Experimental | Procedure: Pericapsular nerve group (PENG) blockThis group includes participants who will receive the pericapsular nerve group (PENG) block after surgical intervention. |
| NO PENG Block Group | No intervention | –This group includes participants who will not receive the pericapsular nerve group (PENG) block after surgical intervention and will be considered our control group. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Patient age 18 years or older
- Acetabular Fracture amenable to surgery through the Kocher-Langenbeck approach
- Full weight-bearing capacity prior to the trauma
- Providing written informed consent
Key exclusion criteria (12 listed)
- Age less than 18 years old
- Fracture pattern not amenable to surgery through Kocher-Langenbeck approach
- Lower extremity fracture ipsilateral to the acetabular fracture
- Any traumatic injury that requires surgical management by other surgical specialty
- Bilateral Acetabular Fractures
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Pericapsular nerve group (PENG) blockPENG Block is a regional block technique well documented in the literature for certain orthopedic injuries and interventions. However, the efficacy of this intervention on acetabular fracture fixation has not been well studied or addressed in previous literature. | Procedure or surgery | PENG Block Group |
Primary outcome
Numeric Pain Rating Scale (NPRS)
Time frame: From surgery to 36 hours after surgery (12 hour Intervals)
The NPRS is an 11-point scale scored from 0-10, with " 0 " representing no pain and "10" being the most intense pain experienced. Patients verbally select a value that is most in line with the intensity of pain that they have experienced at each time point under evaluation.
2 secondary outcomes
Morphine Miligram Equivalent (MME)
Time frame: From surgery to 36 hours after surgery (12 hour Intervals)
Postoperative and Block Associated Complications
Time frame: From surgery to 36 hours after surgery
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Oct 2026.
- Individual participant dataSharing planned: Yes. Data will be stored in an encrypted digital file and made available for file sharing upon a valid request.
Related trials for Acetabular Fractures
Not yet recruitingObservational study
3D-Printed Pelvic Models for Planning Complex Total Hip Arthroplasty
Developmental Dysplasia of the Hip, Acetabular Bone Loss
Active, not recruitingPhase 2
Stoppa Approach Vs Anterior & Posterior Fixation in Management of BC Fracture Acetabulum
Evaluation of Isolated Stoppa Approach in BC Fracture Acetabulum
RecruitingObservational study
Pelvic and Acetabular Fracture: A Prospective Observational Study
Pelvic Fracture, Acetabular Fracture
Not yet recruitingObservational study
Functional and Radiological Outcomes of Pediatric Acetabular Fracture Management
Acetabular Fractures in Pediatrics
RecruitingObservational study
RELIEVED (REgionaL anesthesIa PElVic fracturEs stuDy) Study. Regional Anesthesia (RA) Techniques for Pain Management in Pelvic Fractures: A Prospective, Monocentric, Pilot Cohort Study.
Pelvic Bone Injury, Pelvis Injury
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Luis Lojo Sojo, MD principal investigator
University of Puerto Rico
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Pericapsular nerve group (PENG) block in people with Acetabular Fractures, run by University of Puerto Rico at 1 site in Puerto Rico.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 23 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Puerto Rico. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Numeric Pain Rating Scale (NPRS) (time frame: From surgery to 36 hours after surgery (12 hour Intervals)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Oct 2026.