Mandibular Canal VisibilityNCT07752914
Radiographic Predictors of the Mandibular Lateral Lingual Canal
An observational study of Mandibular Canal Visibility and MANDIBLE, run by Recep Tayyip Erdogan University Training and Research Hospital.
Trial summary
The purpose of this retrospective observational study is to investigate whether mandibular canal dimensions and sublingual fossa morphology can serve as radiographic predictors of the mandibular lateral lingual canal (MLLC) using cone-beam computed tomography (CBCT). Read more about this study
- Who is it for?
- Ages 18 to 75 yearsHealthy volunteers can take part
- Conditions the study is for
- Mandibular Canal Visibility, MANDIBLE, CBCT Segmentation
- How many people
- 210 participants
- Where
- No sites listed yet
- Study dates
- 4 Aug 2026to 30 Sep 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: The study population will consist of adults aged 18 to 75 years with previously acquired diagnostic cone-beam computed tomography (CBCT) images archived in the Department of Oral and Maxillofacial Radiology at Recep Tayyip Erdoğan University Faculty of Dentistry. Only individuals with a unilateral mandibular lateral lingual canal (MLLC) identified on CBCT images and meeting the eligibility criteria will be included.
Who may be able to join
- Individuals aged 18 to 75 years.
- Availability of previously acquired cone-beam computed tomography (CBCT) images obtained for diagnostic purposes.
- Presence of a unilateral mandibular lateral lingual canal (MLLC) on CBCT images.
- CBCT images of sufficient diagnostic quality to evaluate the location, diameter, and course of the MLLC.
- Both mandibular sides included in the same CBCT examination, allowing comparison between the side with the MLLC and the contralateral side.
- Absence of significant motion artifacts, metal artifacts, or reconstruction errors in the regions to be measured.
Who cannot join
- CBCT images of insufficient quality for morphometric measurement or anatomical assessment.
- Inability to clearly identify the mandibular canal, mental foramen, MLLC, or sublingual fossa boundaries.
- Presence of bilateral mandibular lateral lingual canals.
- History of surgery, trauma, fracture, resection, bone grafting, or implant placement in the mandibular region under evaluation.
- Motion or metal artifacts that prevent reliable visualization or measurement of the anatomical structures.
- History of systemic disease or syndrome affecting craniofacial or mandibular development.
- Presence of cystic or tumoral lesions, exostoses, or other pathological changes affecting the region of interest.
- History of orthodontic treatment affecting the region evaluated.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Mandibular Canal Dimensions and Sublingual Fossa Morphology as Predictors of the Mandibular Lateral Lingual Canal
The purpose of this retrospective observational study is to investigate whether mandibular canal dimensions and sublingual fossa morphology can serve as radiographic predictors of the mandibular lateral lingual canal (MLLC) using cone-beam computed tomography (CBCT). CBCT images of adults with unilateral MLLC will be retrospectively evaluated. Mandibular canal diameter, mental foramen diameter, and sublingual fossa depth will be compared between the side with the MLLC and the contralateral side. In addition, the location, diameter, and course of the MLLC will be analyzed to identify radiographic features associated with its presence and to improve preoperative assessment for mandibular surgical procedures.
- Conditions
- Mandibular Canal Visibility, MANDIBLE, CBCT Segmentation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Side With Mandibular Lateral Lingual Canal | Adult participants with unilateral mandibular lateral lingual canal (MLLC) identified on cone-beam computed tomography (CBCT). Morphometric measurements, including mandibular canal diameter, mental foramen diameter, sublingual fossa depth, and MLLC characteristics, will be obtained from the side containing the MLLC. | |
| Contralateral Side Without Mandibular Lateral Lingual Canal | The contralateral side of the same participants without a mandibular lateral lingual canal. Morphometric measurements will be obtained using the same methodology and compared with the side containing the MLLC. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Mandibular Canal Diameter
Mandibular canal diameter will be measured in millimeters (mm) on coronal CBCT images at the level of the mandibular first molar furcation on both the side with the mandibular lateral lingual canal (MLLC) and the contralateral side. Higher values indicate a larger mandibular canal diameter.
Measured: Baseline (retrospective CBCT assessment)
Secondary outcomes (4)
Mental Foramen Diameter
Mental foramen diameter will be measured in millimeters (mm) in the superoinferior direction on CBCT images on both sides. Higher values indicate a larger mental foramen diameter.
Measured: Baseline (retrospective CBCT assessment)
Sublingual Fossa Depth
Sublingual fossa depth will be measured in millimeters (mm) as the perpendicular distance from the deepest point of the sublingual fossa to a reference line connecting the superior and inferior borders of the lingual cortical surface. Higher values indicate a deeper sublingual fossa.
Measured: Baseline (retrospective CBCT assessment)
Mandibular Lateral Lingual Canal Diameter
The diameter of the mandibular lateral lingual canal (MLLC) foramen will be measured in millimeters (mm) on CBCT images. Higher values indicate a larger MLLC diameter.
Measured: Baseline (retrospective CBCT assessment)
Mandibular Lateral Lingual Canal Location
The anatomical location of the mandibular lateral lingual canal will be determined according to the tooth region through which the canal courses. The outcome will be reported as the frequency and percentage of canals identified in each anatomical location.
Measured: Baseline (retrospective CBCT assessment)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Aug 2026
- Study start4 Aug 2026 (estimated)
- Primary completion10 Sep 2026 (estimated)
- Study completion30 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Mandibular Canal VisibilityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Retrospective
- Enrolment
- 210 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, DİLARA NİL GÜNAÇAR, Recep Tayyip Erdogan University Training and Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07752914
- Sponsor's protocol ID
- 2026/331
- Status last verified
- Aug 2026
- First submitted
- 2 Aug 2026
- Last updated
- 7 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 7 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Mandibular Canal Dimensions and Sublingual Fossa Morphology as Predictors of the Mandibular Lateral Lingual Canal
- ClinicalTrials.gov ID
- NCT07752914
- Acronym / sponsor ID
- 2026/331
- Conditions
- Mandibular Canal Visibility, MANDIBLE, CBCT Segmentation
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 210 participants (estimated)
- Lead sponsor
- Recep Tayyip Erdogan University Training and Research HospitalUniversity, hospital or other
- Study start
- 4 Aug 2026 (estimated)
- Primary completion
- 10 Sep 2026 (estimated)
- Study completion
- 30 Sep 2026 (estimated)
- First posted
- 7 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this retrospective observational study is to investigate whether mandibular canal dimensions and sublingual fossa morphology can serve as radiographic predictors of the mandibular lateral lingual canal (MLLC) using cone-beam computed tomography (CBCT). CBCT images of adults with unilateral MLLC will be retrospectively evaluated. Mandibular canal diameter, mental foramen diameter, and sublingual fossa depth will be compared between the side with the MLLC and the contralateral side. In addition, the location, diameter, and course of the MLLC will be analyzed to identify radiographic features associated with its presence and to improve preoperative assessment for mandibular surgical procedures.
Study design
- Observational model
- Case-control
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Side With Mandibular Lateral Lingual Canal | – | –Adult participants with unilateral mandibular lateral lingual canal (MLLC) identified on cone-beam computed tomography (CBCT). Morphometric measurements, including mandibular canal diameter, mental foramen diameter, sublingual fossa depth, and MLLC characteristics, will be obtained from the side containing the MLLC. |
| Contralateral Side Without Mandibular Lateral Lingual Canal | – | –The contralateral side of the same participants without a mandibular lateral lingual canal. Morphometric measurements will be obtained using the same methodology and compared with the side containing the MLLC. |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- The study population will consist of adults aged 18 to 75 years with previously acquired diagnostic cone-beam computed tomography (CBCT) images archived in the Department of Oral and Maxillofacial Radiology at Recep Tayyip Erdoğan University Faculty of Dentistry. Only individuals with a unilateral mandibular lateral lingual canal (MLLC) identified on CBCT images and meeting the eligibility criteria will be included.
Key inclusion criteria (6 listed)
- Individuals aged 18 to 75 years.
- Availability of previously acquired cone-beam computed tomography (CBCT) images obtained for diagnostic purposes.
- Presence of a unilateral mandibular lateral lingual canal (MLLC) on CBCT images.
- CBCT images of sufficient diagnostic quality to evaluate the location, diameter, and course of the MLLC.
- Both mandibular sides included in the same CBCT examination, allowing comparison between the side with the MLLC and the contralateral side.
Key exclusion criteria (8 listed)
- CBCT images of insufficient quality for morphometric measurement or anatomical assessment.
- Inability to clearly identify the mandibular canal, mental foramen, MLLC, or sublingual fossa boundaries.
- Presence of bilateral mandibular lateral lingual canals.
- History of surgery, trauma, fracture, resection, bone grafting, or implant placement in the mandibular region under evaluation.
- Motion or metal artifacts that prevent reliable visualization or measurement of the anatomical structures.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Mandibular Canal Diameter
Time frame: Baseline (retrospective CBCT assessment)
Mandibular canal diameter will be measured in millimeters (mm) on coronal CBCT images at the level of the mandibular first molar furcation on both the side with the mandibular lateral lingual canal (MLLC) and the contralateral side. Higher values indicate a larger mandibular canal diameter.
4 secondary outcomes
Mental Foramen Diameter
Time frame: Baseline (retrospective CBCT assessment)
Sublingual Fossa Depth
Time frame: Baseline (retrospective CBCT assessment)
Mandibular Lateral Lingual Canal Diameter
Time frame: Baseline (retrospective CBCT assessment)
Mandibular Lateral Lingual Canal Location
Time frame: Baseline (retrospective CBCT assessment)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Aug 2026.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
An observational study of Mandibular Canal Visibility and MANDIBLE, run by Recep Tayyip Erdogan University Training and Research Hospital.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 7 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact dilara nil günaçar (05412940104, dilaranil.tomrukcu@erdogan.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mandibular Canal Diameter (time frame: Baseline (retrospective CBCT assessment)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Aug 2026.