Dementia Risk Cognitive Decline Cognitive Impairment Healthy Cognitive AgingDementiaNCT07747610
Effects of Lifestyle and Cognitive Play-Based Nursing Intervention on Dementia Risk
A study testing A structured nurse-led multidomain intervention in people with Dementia Risk Cognitive Decline Cognitive Impairment Healthy Cognitive Aging, run by Al-Zaytoonah University of Jordan at 1 site in Jordan.
Trial summary
This study evaluated whether a nurse-led lifestyle modification program combined with cognitive play-based training could reduce dementia risk among older adults living in residential care homes. A total of 134 older adults from seven residential care homes in Cairo, Egypt, participated in the study. Read more about this study
- Who is it for?
- Ages 18 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- Dementia Risk Cognitive Decline Cognitive Impairment Healthy Cognitive Aging
- What is being tested?
- A structured nurse-led multidomain intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 134 participants
- Where
- 1 siteJordan
- Study dates
- 4 Apr 2026to 7 Jun 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- The participants had to be aged 60 years or above, be male or female, have risk factors for dementia (such as mild cognitive impairment, hypertension, or diabetes), and provide informed consent either directly or through a legal representative
Who cannot join
- advanced dementia (AMTS score ≤4) or severe neurological/medical conditions that might interfere with the intervention or outcome assessment
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Lifestyle and Cognitive Play-Based Nursing Intervention on Dementia Risk Scores Among Elders in Residential Care: A Controlled Quasi-Experimental Study
This study evaluated whether a nurse-led lifestyle modification program combined with cognitive play-based training could reduce dementia risk among older adults living in residential care homes. A total of 134 older adults from seven residential care homes in Cairo, Egypt, participated in the study. Participants received either the multidomain nursing intervention or usual care. The intervention included education on brain-healthy lifestyle behaviors and cognitive play activities designed to improve cognitive health and reduce modifiable dementia risk factors. The study assessed dementia awareness, dementia risk using the Lifestyle for Brain Health Risk Assessment (LIBRA), cognitive function, nutritional status, depression, and physiological and anthropometric measures. The findings showed that participants who received the intervention had greater dementia awareness, lower dementia risk scores, and better cognitive screening outcomes than those receiving usual care, supporting the effectiveness of multidomain nurse-led interventions for dementia prevention.
Read the detailed description
Dementia is a major public health challenge, and many of its risk factors are modifiable. Lifestyle interventions addressing physical activity, healthy nutrition, cardiovascular risk factors, social engagement, and cognitive stimulation have demonstrated potential to delay cognitive decline and reduce dementia risk. Nurses are well positioned to deliver multidomain interventions that promote healthy cognitive aging among older adults residing in long-term care facilities.
- Being tested
- A structured nurse-led multidomain intervention
- Keywords
- Lifestyle, Cognitive Play-based Training, Dementia Risk Factors, Seniors in Residential Care
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
A structured nurse-led multidomain interventionBehavioural
Also called Participants received a structured nurse-led multidomain intervention consisting of lifestyle modification education and cognitive play-based training
A structured nurse-led multidomain program consisting of lifestyle modification education and cognitive play-based training to improve brain health and reduce modifiable dementia risk factors.
| Study group | Role | What they receive |
|---|---|---|
| Nurse-Led Lifestyle and Cognitive Play Intervention | Experimental | Participants received a structured nurse-led multidomain intervention consisting of lifestyle modification education and cognitive play-based training designed to improve brain health, reduce modifiable dementia risk factors, and promote healthy cognitive aging. The intervention was delivered in addition to routine care. Receives: Behavioral: A structured nurse-led multidomain intervention |
| Routine Care | No intervention | Participants received the usual care routinely provided in the residential care homes and did not receive the nurse-led lifestyle modification or cognitive play-based intervention during the study period. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Dementia Risk Score
Change in dementia risk measured using the Lifestyle for Brain Health Risk Assessment (LIBRA). Lower LIBRA scores indicate a reduction in modifiable dementia risk factors following the nurse-led lifestyle
Measured: 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Aug 2026
- Study start4 Apr 2026
- Primary completion5 May 2026
- Study completion7 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Dementia Risk Cognitive Decline Cognitive Impairment Healthy Cognitive AgingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants were assigned to one of two parallel groups: an intervention group that received a nurse-led lifestyle modification and cognitive play-based program and a control group that received routine care. Outcomes were assessed at baseline and follow-up to compare the effectiveness of the intervention on dementia risk and cognitive health.
- Masking
- None (open label)
- Enrolment
- 134 participants (actual)
Sponsor and investigators
- Lead sponsor
- Al-Zaytoonah University of Jordan
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Eman Abdelfatah Shokr, Al-Zaytoonah University of Jordan
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07747610
- Sponsor's protocol ID
- FAN/ 226 /2025
- Acronym
- Dementia
- Status last verified
- Oct 2025
- First submitted
- 31 Jul 2026
- Last updated
- 5 Aug 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified individual participant data underlying the published results, including demographic characteristics and outcome measures, will be made available to qualified researchers upon reasonable request to the corresponding author, following publication of the study and subject to institutional approval and applicable ethical and data-sharing regulations.
Study at a glance
From the registry record, last updated by the sponsor on 5 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Lifestyle and Cognitive Play-Based Nursing Intervention on Dementia Risk Scores Among Elders in Residential Care: A Controlled Quasi-Experimental Study
- ClinicalTrials.gov ID
- NCT07747610
- Acronym / sponsor ID
- Dementia / FAN/ 226 /2025
- Keywords
- Lifestyle, Cognitive Play-based Training, Dementia Risk Factors, Seniors in Residential Care
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 134 participants (actual)
- Lead sponsor
- Al-Zaytoonah University of JordanUniversity, hospital or other
- Study start
- 4 Apr 2026 (actual)
- Primary completion
- 5 May 2026 (actual)
- Study completion
- 7 Jun 2026 (actual)
- First posted
- 5 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study evaluated whether a nurse-led lifestyle modification program combined with cognitive play-based training could reduce dementia risk among older adults living in residential care homes. A total of 134 older adults from seven residential care homes in Cairo, Egypt, participated in the study. Participants received either the multidomain nursing intervention or usual care. The intervention included education on brain-healthy lifestyle behaviors and cognitive play activities designed to improve cognitive health and reduce modifiable dementia risk factors. The study assessed dementia awareness, dementia risk using the Lifestyle for Brain Health Risk Assessment (LIBRA), cognitive function, nutritional status, depression, and physiological and anthropometric measures. The findings showed that participants who received the intervention had greater dementia awareness, lower dementia risk scores, and better cognitive screening outcomes than those receiving usual care, supporting the effectiveness of multidomain nurse-led interventions for dementia prevention.
Detailed description
Dementia is a major public health challenge, and many of its risk factors are modifiable. Lifestyle interventions addressing physical activity, healthy nutrition, cardiovascular risk factors, social engagement, and cognitive stimulation have demonstrated potential to delay cognitive decline and reduce dementia risk. Nurses are well positioned to deliver multidomain interventions that promote healthy cognitive aging among older adults residing in long-term care facilities.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants were assigned to one of two parallel groups: an intervention group that received a nurse-led lifestyle modification and cognitive play-based program and a control group that received routine care. Outcomes were assessed at baseline and follow-up to compare the effectiveness of the intervention on dementia risk and cognitive health.
| Arm | Type | Receives |
|---|---|---|
| Nurse-Led Lifestyle and Cognitive Play Intervention | Experimental | Behavioral: A structured nurse-led multidomain interventionParticipants received a structured nurse-led multidomain intervention consisting of lifestyle modification education and cognitive play-based training designed to improve brain health, reduce modifiable dementia risk factors, and promote healthy cognitive aging. The intervention was delivered in addition to routine care. |
| Routine Care | No intervention | –Participants received the usual care routinely provided in the residential care homes and did not receive the nurse-led lifestyle modification or cognitive play-based intervention during the study period. |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- The participants had to be aged 60 years or above, be male or female, have risk factors for dementia (such as mild cognitive impairment, hypertension, or diabetes), and provide informed consent either directly or through a legal representative
Key exclusion criteria (1 listed)
- advanced dementia (AMTS score ≤4) or severe neurological/medical conditions that might interfere with the intervention or outcome assessment
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| A structured nurse-led multidomain interventionAlso: Participants received a structured nurse-led multidomain intervention consisting of lifestyle modification education and cognitive play-based trainingA structured nurse-led multidomain program consisting of lifestyle modification education and cognitive play-based training to improve brain health and reduce modifiable dementia risk factors. | Behavioural | Nurse-Led Lifestyle and Cognitive Play Intervention |
Primary outcome
Dementia Risk Score
Time frame: 3 months
Change in dementia risk measured using the Lifestyle for Brain Health Risk Assessment (LIBRA). Lower LIBRA scores indicate a reduction in modifiable dementia risk factors following the nurse-led lifestyle
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Aug 2026.
- Individual participant dataSharing planned: Yes. De-identified individual participant data underlying the published results, including demographic characteristics and outcome measures, will be made available to qualified researchers upon reasonable request to the corresponding author, following publication of the study and subject to institutional approval and applicable ethical and data-sharing regulations.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing A structured nurse-led multidomain intervention in people with Dementia Risk Cognitive Decline Cognitive Impairment Healthy Cognitive Aging, run by Al-Zaytoonah University of Jordan at 1 site in Jordan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Jordan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Dementia Risk Score (time frame: 3 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Aug 2026.