Orofacial PainOSQ-MUSNCT07714837
Orofacial Pain and Oral Health-Related Quality of Life in Musicians in German Amateur Orchestras
An observational study of Orofacial Pain and Sleep Bruxism, run by University Medical Center Goettingen at 1 site in Germany.
Trial summary
This cross-sectional online survey investigates the prevalence of orofacial pain, sleep-related problems, and oral health-related quality of life (OHRQoL) among adult musicians who play in German amateur orchestras. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Orofacial Pain, Sleep Bruxism, Oral Health Related Quality of Life (OHRQoL)
- What is being tested?
- Questionaire
- Type of treatment
- Pill or oral medicine
- How many people
- 400 participants
- Where
- 1 siteGermany
- Study dates
- 1 Sep 2026to 1 Nov 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Adult musicians (≥ 18 years) who are active members of a German amateur orchestra, recruited via a standardized online questionnaire sent to all 863 German amateur orchestras and via the Federal Association of Amateur Music - Symphony and Chamber Orchestras newsletter.
Who may be able to join
- Age ≥ 18 years
- Active membership in a German amateur orchestra
- Consent to study participation (given by completing the questionnaire)
Who cannot join
- Age < 18 years
- Missing / declined consent to participate
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Germany1 site, 1 recruiting
- Recruiting
University Medical Center Göttingen
Göttingen, 37077
Felix Marschner, Dr, MSc, +49 551 39-60870, felix.marschner@med.uni-goettingen.de
About this study
Official title: Orofacial Pain, Sleep-Related Problems, and Oral Health-Related Quality of Life Among Musicians in German Amateur Orchestras: A Cross-Sectional Online Survey
This cross-sectional online survey investigates the prevalence of orofacial pain, sleep-related problems, and oral health-related quality of life (OHRQoL) among adult musicians who play in German amateur orchestras. Participants complete a single, anonymous, approximately 10-minute questionnaire covering demographic data, orofacial pain, sleep bruxism, perceived stress, sleep quality, and the German short version of the Oral Health Impact Profile (OHIP-14). The study examines whether these outcomes differ between instrument groups (woodwind, brass, string, percussion, and other instruments). The primary hypothesis is that players of wind instruments (woodwind and brass) more frequently report orofacial pain and experience a different OHRQoL than players of other instrument groups. The study has a pilot character and aims to generate data to inform future research and targeted dental care concepts for this population.
Read the detailed description
Background: Germany has both one of the world's highest densities of professional orchestras and a rich amateur orchestra landscape, with approximately 30,300 musicians active across 863 amateur orchestras (BDLO). While making music, amateur musicians are exposed to physical and psychological demands that may affect oral health. Orofacial pain in musicians has been associated with sleep bruxism, perceived stress, and reduced sleep quality, all of which may negatively affect OHRQoL. Instrument-specific oral effects have been described particularly for wind instrumentalists compared with other instrument groups (e.g., string and percussion), related to specific playing technique and the coordinated action of the orofacial musculature. Playing a wind instrument has been linked to temporomandibular dysfunction, orofacial pain, and increased masticatory muscle activity. Unlike professional musicians, amateur musicians often have more heterogeneous and less systematic instrumental training, so a suboptimal playing technique and unfavorable posture may contribute to muscular overload. To date, no systematically collected data on orofacial pain, sleep-related problems, and OHRQoL of amateur musicians in Germany are available.
Objective: To investigate orofacial pain, sleep-related problems, and OHRQoL among musicians in German amateur orchestras and to identify possible differences between instrument groups (woodwind, brass, string, percussion, and other instruments such as piano, harp, celesta).
Hypothesis: Amateur musicians who play wind instruments (woodwind and brass) more frequently suffer from orofacial pain and experience a different OHRQoL than amateur musicians who play other instrument groups.
Methods: This is a monocentric, cross-sectional online survey. A standardized online questionnaire is distributed to all 863 German amateur orchestras and additionally disseminated via the BDLO newsletter. The questionnaire covers demographic data (age, sex, instrument, duration of amateur orchestra membership) and specific questions on orofacial pain, sleep bruxism, perceived stress, and sleep quality. The German version of the OHIP-14 is used to assess OHRQoL. The survey is provided electronically via the University Medical Center Göttingen electronic survey system (EvaSys, ISO 27001 certified). Participation is voluntary and anonymous; completion of the questionnaire constitutes consent. Completion takes approximately 10 minutes, and the survey closes after 12 weeks for each participant. A reminder is sent to the orchestras and via the BDLO newsletter after 6 weeks.
Statistical analysis: Continuous variables are presented as mean ± standard deviation or as median with interquartile range; categorical variables as absolute and relative frequencies. Group comparisons use the chi-square test, t-test, Mann-Whitney U test, or Kruskal-Wallis test as appropriate. Multivariable logistic regression is used to identify independent predictors of the presence of orofacial pain, and linear regression for the OHIP-14 summary score, each adjusted for relevant covariates. Odds ratios are reported with 95% confidence intervals and adjusted for age and sex.
The study is conducted in accordance with the current version of the Declaration of Helsinki. The protocol is submitted to the Ethics Committee of the University Medical Center Göttingen prior to the start of the survey.
- Being tested
- Questionaire
- Keywords
- amateur musicians, orchestra, wind instruments, brass, woodwind, orofacial pain, sleep bruxism, oral health-related quality of life
- Medical subject headings
- Facial Pain, Sleep Bruxism
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
QuestionaireOther
Percentage (%) of surveyed musicians with presence of orofacial pain and other studied conditions like sleep bruxism, sleep disorders, and Oral Health-Related Quality of Life
| Study group | Role | What they receive |
|---|---|---|
| Orchestra musicians | musicians in German amateur orchestras Receives: Other: Questionaire |
What is being measured
The primary outcome is the main question the study is designed to answer.
Presence of orofacial pain
Presence of orofacial pain - self-reported via standardized questionnaire, compared between instrument groups. Scale: no pain, pain is present occasionally, pain is continuous
Measured: 10 minutes
Oral Health-Related Quality of Life
Oral Health-Related Quality of Life (OHIP-14 summary score) - German version; summary score range 0-56, higher scores indicating worse OHRQoL; compared between instrument groups.
Measured: 10 minutes
Secondary outcomes (3)
Self-reported sleep bruxism questionnaire
Prevalence of self-reported sleep bruxism, self-reported via standardized questionnaire, compared between instrument groups. Scale: never, seldom, occasionally, almost every night, every night
Measured: 10 minutes
Self-reported perceived stress questionnaire
Perceived stress, self-reported via standardized questionnaire, compared between instrument groups. Scale: not at all, seldom, occasionally, rather often, very often
Measured: 10 minutes
Self-reported sleep quality questionnaire
Self-reported sleep quality, self-reported via standardized questionnaire, compared between instrument groups.
Measured: 10 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Jul 2026
- Study start1 Sep 2026
- Primary completion1 Nov 2026 (estimated)
- Study completion1 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Orofacial PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 400 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Medical Center Goettingen
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Felix Marschner, University Medical Center Goettingen
- Investigators
- Felix Marschner, Dr, MSc, Principal investigator, University Medical Center Göttingen
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07714837
- Sponsor's protocol ID
- 24/6/26
- Acronym
- OSQ-MUS
- Status last verified
- Sep 2026
- First submitted
- 6 Jul 2026
- Last updated
- 4 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 4 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Orofacial Pain, Sleep-Related Problems, and Oral Health-Related Quality of Life Among Musicians in German Amateur Orchestras: A Cross-Sectional Online Survey
- ClinicalTrials.gov ID
- NCT07714837
- Acronym / sponsor ID
- OSQ-MUS / 24/6/26
- Keywords
- amateur musicians, orchestra, wind instruments, brass, woodwind, orofacial pain, sleep bruxism, oral health-related quality of life
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 400 participants (estimated)
- Lead sponsor
- University Medical Center GoettingenUniversity, hospital or other
- Study start
- 1 Sep 2026 (actual)
- Primary completion
- 1 Nov 2026 (estimated)
- Study completion
- 1 Nov 2026 (estimated)
- First posted
- 20 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This cross-sectional online survey investigates the prevalence of orofacial pain, sleep-related problems, and oral health-related quality of life (OHRQoL) among adult musicians who play in German amateur orchestras. Participants complete a single, anonymous, approximately 10-minute questionnaire covering demographic data, orofacial pain, sleep bruxism, perceived stress, sleep quality, and the German short version of the Oral Health Impact Profile (OHIP-14). The study examines whether these outcomes differ between instrument groups (woodwind, brass, string, percussion, and other instruments). The primary hypothesis is that players of wind instruments (woodwind and brass) more frequently report orofacial pain and experience a different OHRQoL than players of other instrument groups. The study has a pilot character and aims to generate data to inform future research and targeted dental care concepts for this population.
Detailed description
Background: Germany has both one of the world's highest densities of professional orchestras and a rich amateur orchestra landscape, with approximately 30,300 musicians active across 863 amateur orchestras (BDLO). While making music, amateur musicians are exposed to physical and psychological demands that may affect oral health. Orofacial pain in musicians has been associated with sleep bruxism, perceived stress, and reduced sleep quality, all of which may negatively affect OHRQoL. Instrument-specific oral effects have been described particularly for wind instrumentalists compared with other instrument groups (e.g., string and percussion), related to specific playing technique and the coordinated action of the orofacial musculature. Playing a wind instrument has been linked to temporomandibular dysfunction, orofacial pain, and increased masticatory muscle activity. Unlike professional musicians, amateur musicians often have more heterogeneous and less systematic instrumental training, so a suboptimal playing technique and unfavorable posture may contribute to muscular overload. To date, no systematically collected data on orofacial pain, sleep-related problems, and OHRQoL of amateur musicians in Germany are available.
Objective: To investigate orofacial pain, sleep-related problems, and OHRQoL among musicians in German amateur orchestras and to identify possible differences between instrument groups (woodwind, brass, string, percussion, and other instruments such as piano, harp, celesta).
Hypothesis: Amateur musicians who play wind instruments (woodwind and brass) more frequently suffer from orofacial pain and experience a different OHRQoL than amateur musicians who play other instrument groups.
Methods: This is a monocentric, cross-sectional online survey. A standardized online questionnaire is distributed to all 863 German amateur orchestras and additionally disseminated via the BDLO newsletter. The questionnaire covers demographic data (age, sex, instrument, duration of amateur orchestra membership) and specific questions on orofacial pain, sleep bruxism, perceived stress, and sleep quality. The German version of the OHIP-14 is used to assess OHRQoL. The survey is provided electronically via the University Medical Center Göttingen electronic survey system (EvaSys, ISO 27001 certified). Participation is voluntary and anonymous; completion of the questionnaire constitutes consent. Completion takes approximately 10 minutes, and the survey closes after 12 weeks for each participant. A reminder is sent to the orchestras and via the BDLO newsletter after 6 weeks.
Statistical analysis: Continuous variables are presented as mean ± standard deviation or as median with interquartile range; categorical variables as absolute and relative frequencies. Group comparisons use the chi-square test, t-test, Mann-Whitney U test, or Kruskal-Wallis test as appropriate. Multivariable logistic regression is used to identify independent predictors of the presence of orofacial pain, and linear regression for the OHIP-14 summary score, each adjusted for relevant covariates. Odds ratios are reported with 95% confidence intervals and adjusted for age and sex.
The study is conducted in accordance with the current version of the Declaration of Helsinki. The protocol is submitted to the Ethics Committee of the University Medical Center Göttingen prior to the start of the survey.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Orchestra musicians | – | Other: Questionairemusicians in German amateur orchestras |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Adult musicians (≥ 18 years) who are active members of a German amateur orchestra, recruited via a standardized online questionnaire sent to all 863 German amateur orchestras and via the Federal Association of Amateur Music - Symphony and Chamber Orchestras newsletter.
Key inclusion criteria (3 listed)
- Age ≥ 18 years
- Active membership in a German amateur orchestra
- Consent to study participation (given by completing the questionnaire)
Key exclusion criteria (2 listed)
- Age < 18 years
- Missing / declined consent to participate
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| QuestionairePercentage (%) of surveyed musicians with presence of orofacial pain and other studied conditions like sleep bruxism, sleep disorders, and Oral Health-Related Quality of Life | Other | Orchestra musicians |
Primary outcome
Presence of orofacial pain
Time frame: 10 minutes
Presence of orofacial pain - self-reported via standardized questionnaire, compared between instrument groups. Scale: no pain, pain is present occasionally, pain is continuous
Oral Health-Related Quality of Life
Time frame: 10 minutes
Oral Health-Related Quality of Life (OHIP-14 summary score) - German version; summary score range 0-56, higher scores indicating worse OHRQoL; compared between instrument groups.
3 secondary outcomes
Self-reported sleep bruxism questionnaire
Time frame: 10 minutes
Self-reported perceived stress questionnaire
Time frame: 10 minutes
Self-reported sleep quality questionnaire
Time frame: 10 minutes
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Sep 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Felix Marschner, Dr, MSc principal investigator
University Medical Center Göttingen
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Orofacial Pain and Sleep Bruxism, run by University Medical Center Goettingen at 1 site in Germany.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 4 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Germany. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Felix Marschner, Dr, MSc (+49 551 39-60870, felix.marschner@med.uni-goettingen.de), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Presence of orofacial pain (time frame: 10 minutes). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Sep 2026; AzTrials last refreshed its copy on 8 Nov 2026.