Wrist Joint Overuse SyndromeNCT07714031
Comparative Effects of 3-Dimensional Articular and Soft Tissue Myofascial Release Approach in Patients With Overuse Syndrome of Wrist Joint
A study testing 3- dimensional Articular fascial release approach and 3 Dimensional soft tissue release approach in people with Wrist Joint Overuse Syndrome, run by University of Faisalabad at 1 site in Pakistan.
Trial summary
Overuse syndrome or RSI is challenging condition among clinicians now a days. These are MSK disorders which are related to bones, muscles and tendons peripheral nerve entrapment and vascular changes. These MSK disorders commonly effects back, neck and upper limbs although it least effect lower limbs. Read more about this study
- Who is it for?
- Ages 20 to 50 years
- Conditions the study is for
- Wrist Joint Overuse Syndrome
- What is being tested?
- 3- dimensional Articular fascial release approach and 3 Dimensional soft tissue release approach
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 46 participants
- Where
- 1 sitePakistan
- Study dates
- 14 Jul 2026to 9 Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients between 20-55 years of age
- Male and female
- Participants involved in repetitive movements of hands e.g computer workers ( 2026/3/4
- Patients who have gradual onset of pain not sudden
- Reproduction of pain with wrist flexion, extension, ulnar and radial deviation
- Patients with \>10% reduced ROM of wrist joint as compared to contralateral side
- Participants who will willing to participate
Who cannot join
- Specific disease of wrist e.g RA, gout, infection
- Patients with traumatic wrist pathology (such as scaphoid fracture, distal radius fracture)
- Neuropathic compromise patients such as diabetic neuropathy, CTS
- Open wound
- Suspected or confirmed malignancy in wrist joint
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Dr Rubina Zulfqar
Faisalabad, Punjab Province, 38000
Dr Rubina Zulfqar, +923414291664, drrubinazulfqar355@gmail.com
About this study
Overuse syndrome or RSI is challenging condition among clinicians now a days. These are MSK disorders which are related to bones, muscles and tendons peripheral nerve entrapment and vascular changes. These MSK disorders commonly effects back, neck and upper limbs although it least effect lower limbs. These problems occur from repetitive movements, ergonomic hazards, awkward postures and work related problems. This study aims to assess the comparative effects of 3 dimensional articular myofascial release approach and soft tissue myofascial release approach in patients with overuse syndrome of wrist joint. A randomized controlled trial will be conducted age between 20-55 years, both male and female genders will be included diagnosed with overuse syndrome of wrist. Diagnosis will be made on the basis of diagnostic criteria which will include tenderness present in intrinsic muscles and pain in radial ligament of wrist. Participants will be chosen through consecutive sampling.
Each participant will sign a consent form before taking part in the study. According to sample size 46 participants will be divided into two groups. Each group will include 23 participants which will be divided through lottery method. Both groups will receive baseline treatment which will include hot-pack for 15 minutes. Group a will be treated with articular fascial release and group b will be treated with soft tissue release for 3 sessions per week, for 3 weeks. After therapy session both groups will perform wrist rom exercises including wrist flexion, extension, radial and ulnar deviation 5 repetitions each. Outcome measuring tools will be numeric pain rating scale (NPRS) for pain, disabilities of arm, shoulder and hand (DASH) for functional disability, patient rated wrist evaluation (PRWE) specifically wrist functions evaluation and goniometer for range of motion. Data will be investigated through SPSS.
- Conditions
- Wrist Joint Overuse Syndrome
- Being tested
- 3- dimensional Articular fascial release approach, 3 Dimensional soft tissue release approach
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
3- dimensional Articular fascial release approachProcedure or surgery
Hot pack for 15 mins.3- dimensional Articular fascial release approach
3 Dimensional soft tissue release approachProcedure or surgery
Hot pack for 15 mins. 3 Dimensional soft tissue release approach
- Technique: Apply gentle sustained pressure in all three planes. Hold 30-90 seconds while sensing tissue give hold until all the symptoms and fascial release feel. Encourage slow diaphragmatic breathing exhalation facilitates release. 4. Avoid: Pressure on bony surfaces and nerve trunks area 5. Dose and frequency
- Per site 8-12 minutes of fulcrum work (including holds and plane cycles)
- Session: 20-40 minutes total including warm up, 1-3 fulcrum site integration and education
- Frequency: Total 3 weeks, per week 3 sessions, total sessions 7. After treatment will include ROM exercises including wrist flexion, extension, radial deviation and ulnar devi
| Study group | Role | What they receive |
|---|---|---|
| 3- dimensional Articular fascial release approach | Experimental | Not described Receives: Procedure: 3- dimensional Articular fascial release approach |
| 3 Dimensional soft tissue release approach | Experimental | Not described Receives: Procedure: 3 Dimensional soft tissue release approach |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain Intensity
Pain Intensity will be measured by using the Numeric Pain Rating Scale, the patients rate their pain on a scale from 0 (no pain) to 10 (worst possible pain).NPRS scale consists of 11 points in which 0 is no pain while 10 is worst pain.
Measured: 3 weeks
Range of Motion
Range of Motion will be measured by using Goniometry the improvement in ROM shows good results.
Measured: 3 weeks
Secondary outcomes (1)
Functional disability
Functional disability will be measured by using The Disabilities of Arm, Shoulder and Hand (DASH) and Patient-rated wrist evaluation form (PRWE). The DASH questionnaire is consists of thirty items which asses the physical function and symptoms. It involve five options for response of each item. Ultimate score is calculated through the formula below: DASH score = {(sum of n responses)-1}*25, n=number of complete responses, the highest score showed improvement. While The PRWE is a self administrated questionnaire which is patient specific which consist of 15 items. It was designed for measurement of activities of daily living of wrist pain and disability and consist of 2 subscales; pain and function.A score of 100 represent the worst functional score while the score 0 indicate no disability.
Measured: 3 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Jul 2026
- Study start14 Jul 2026 (estimated)
- Primary completion9 Aug 2026 (estimated)
- Study completion9 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Wrist Joint Overuse SyndromeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 46 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Faisalabad
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Rubina Zulfqar, University of Faisalabad
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07714031
- Sponsor's protocol ID
- TUF/EIRB/177/26
- Status last verified
- Jul 2026
- First submitted
- 9 Jun 2026
- Last updated
- 23 Jul 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of 3-Dimensional Articular and Soft Tissue Myofascial Release Approach in Patients With Overuse Syndrome of Wrist Joint
- ClinicalTrials.gov ID
- NCT07714031
- Acronym / sponsor ID
- TUF/EIRB/177/26
- Conditions
- Wrist Joint Overuse Syndrome
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 46 participants (estimated)
- Lead sponsor
- University of FaisalabadUniversity, hospital or other
- Study start
- 14 Jul 2026 (estimated)
- Primary completion
- 9 Aug 2026 (estimated)
- Study completion
- 9 Aug 2026 (estimated)
- First posted
- 20 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Overuse syndrome or RSI is challenging condition among clinicians now a days. These are MSK disorders which are related to bones, muscles and tendons peripheral nerve entrapment and vascular changes. These MSK disorders commonly effects back, neck and upper limbs although it least effect lower limbs. These problems occur from repetitive movements, ergonomic hazards, awkward postures and work related problems. This study aims to assess the comparative effects of 3 dimensional articular myofascial release approach and soft tissue myofascial release approach in patients with overuse syndrome of wrist joint. A randomized controlled trial will be conducted age between 20-55 years, both male and female genders will be included diagnosed with overuse syndrome of wrist. Diagnosis will be made on the basis of diagnostic criteria which will include tenderness present in intrinsic muscles and pain in radial ligament of wrist. Participants will be chosen through consecutive sampling.
Each participant will sign a consent form before taking part in the study. According to sample size 46 participants will be divided into two groups. Each group will include 23 participants which will be divided through lottery method. Both groups will receive baseline treatment which will include hot-pack for 15 minutes. Group a will be treated with articular fascial release and group b will be treated with soft tissue release for 3 sessions per week, for 3 weeks. After therapy session both groups will perform wrist rom exercises including wrist flexion, extension, radial and ulnar deviation 5 repetitions each. Outcome measuring tools will be numeric pain rating scale (NPRS) for pain, disabilities of arm, shoulder and hand (DASH) for functional disability, patient rated wrist evaluation (PRWE) specifically wrist functions evaluation and goniometer for range of motion. Data will be investigated through SPSS.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| 3- dimensional Articular fascial release approach | Experimental | Procedure: 3- dimensional Articular fascial release approach |
| 3 Dimensional soft tissue release approach | Experimental | Procedure: 3 Dimensional soft tissue release approach |
Who may qualify
- Ages
- 20 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- Patients between 20-55 years of age
Key exclusion criteria (5 listed)
- Specific disease of wrist e.g RA, gout, infection
- Patients with traumatic wrist pathology (such as scaphoid fracture, distal radius fracture)
- Neuropathic compromise patients such as diabetic neuropathy, CTS
- Open wound
- Suspected or confirmed malignancy in wrist joint
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| 3- dimensional Articular fascial release approachHot pack for 15 mins.3- dimensional Articular fascial release approach | Procedure or surgery | 3- dimensional Articular fascial release approach |
| 3 Dimensional soft tissue release approachHot pack for 15 mins. 3 Dimensional soft tissue release approach * Technique: Apply gentle sustained pressure in all three planes. Hold 30-90 seconds while sensing tissue give hold until all the symptoms and fascial release feel. Encourage slow diaphragmatic breathing exhalation facilitates release. 4. Avoid: Pressure on bony surfaces and nerve trunks area 5. Dose and frequency * Per site 8-12 minutes of fulcrum work (including holds and plane cycles) * Session: 20-40 minutes total including warm up, 1-3 fulcrum site integration and education 6. Frequency: Total 3 weeks, per week 3 sessions, total sessions 7. After treatment will include ROM exercises including wrist flexion, extension, radial deviation and ulnar devi | Procedure or surgery | 3 Dimensional soft tissue release approach |
Primary outcome
Pain Intensity
Time frame: 3 weeks
Pain Intensity will be measured by using the Numeric Pain Rating Scale, the patients rate their pain on a scale from 0 (no pain) to 10 (worst possible pain).NPRS scale consists of 11 points in which 0 is no pain while 10 is worst pain.
Range of Motion
Time frame: 3 weeks
Range of Motion will be measured by using Goniometry the improvement in ROM shows good results.
1 secondary outcome
Functional disability
Time frame: 3 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jul 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing 3- dimensional Articular fascial release approach and 3 Dimensional soft tissue release approach in people with Wrist Joint Overuse Syndrome, run by University of Faisalabad at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 23 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Dr Rubina Zulfqar (+923414291664, drrubinazulfqar355@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain Intensity (time frame: 3 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jul 2026.