Exercise Performance RecoveryNCT07712653
Effects of Creatine and Carbohydrate Supplementation on Endurance Performance
A study testing Creatine Monohydrate, Carbohydrate and Creatine Monohydrate and Carbohydrate in people with Exercise Performance Recovery, run by California Polytechnic State University-San Luis Obispo at 1 site in United States.
Trial summary
This study will examine the independent and combined effects of creatine and carbohydrate supplementation on exercise performance, compared to placebo. Read more about this study
- Who is it for?
- Ages 18 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Exercise Performance Recovery
- What is being tested?
- Creatine Monohydrate, Carbohydrate and Creatine Monohydrate and Carbohydrate
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 12 participants
- Where
- 1 siteUnited States
- Study dates
- 15 Jul 2026to 1 Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- healthy (i.e. no known cardiovascular disease)
- nonsmoking
- active (regular physical activity ≥150 minutes per week of aerobic exercise and have a VO2 peak ≥35 ml/kg-min)
- a normal BMI (18.5 - 35 kg/m^2)
- between ages 18-40 years old
Who cannot join
- previously taken creatine and/or any other dietary supplement that may interfere with exercise performance
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
California Polytechnic State University
San Luis Obispo, California, 93407
Todd Hagobian, PhD, 805-756-7511, thagobia@calpoly.edu
About this study
This study will examine the independent and combined effects of creatine and carbohydrate supplementation on exercise performance, compared to placebo.
- Conditions
- Exercise Performance Recovery
- Being tested
- Creatine Monohydrate, Carbohydrate, Creatine Monohydrate and Carbohydrate, placebo solution
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Creatine MonohydrateDietary supplement
Creatine monohydrate supplementation 0.5 grams every 20 minutes
CarbohydrateDietary supplement
carbohydrate supplementation 5 grams every 20 minutes
Creatine Monohydrate and CarbohydrateDietary supplement
Creatine supplementation of 0.5 grams and carbohydrate supplementation of 5 grams every 20 minutes.
placebo solutionDietary supplement
Flavored water every 20 minutes
| Study group | Role | What they receive |
|---|---|---|
| Placebo | Placebo comparator | Flavored water every 20 minutes Receives: Dietary Supplement: placebo solution |
| Creatine monohydrate | Experimental | Creatine Monohydrate supplementation every 0.5 grams every 20 minutes Receives: Dietary Supplement: Creatine Monohydrate |
| Carbohydrate | Experimental | Carbohydrate supplementation 5 grams every 20 minutes Receives: Dietary Supplement: Carbohydrate |
| Creatine and Carbohydrate | Experimental | Creatine supplementation at 0.5 gram and carbohydrate supplementation of 5 grams every 20 minutes Receives: Dietary Supplement: Creatine Monohydrate and Carbohydrate |
What is being measured
The primary outcome is the main question the study is designed to answer.
Exercise Time to exhaustion
Time to exhaustion (seconds) during continuous cycling performed at 60% of each participant's maximal cycling power output following supplementation with placebo, creatine monohydrate, or creatine monohydrate plus carbohydrate.
Measured: Change in exercise time to exhaustion ( in seconds) through study completion, over the course of study completion, on average 4 weeks.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jul 2026
- Study start15 Jul 2026 (estimated)
- Primary completion1 Aug 2026 (estimated)
- Study completion1 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Exercise Performance RecoveryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 12 participants (estimated)
Sponsor and investigators
- Lead sponsor
- California Polytechnic State University-San Luis Obispo
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Todd Hagobian, California Polytechnic State University-San Luis Obispo
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07712653
- Sponsor's protocol ID
- 2013-CP
- Status last verified
- Jul 2026
- First submitted
- 8 Jul 2026
- Last updated
- 21 Jul 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: IPD will be available on the Cal Poly Digital Commons website and available upon request.
Study at a glance
From the registry record, last updated by the sponsor on 21 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Creatine and Carbohydrate Supplementation on Endurance Performance
- ClinicalTrials.gov ID
- NCT07712653
- Acronym / sponsor ID
- 2013-CP
- Conditions
- Exercise Performance Recovery
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 12 participants (estimated)
- Lead sponsor
- California Polytechnic State University-San Luis ObispoUniversity, hospital or other
- Study start
- 15 Jul 2026 (estimated)
- Primary completion
- 1 Aug 2026 (estimated)
- Study completion
- 1 Aug 2026 (estimated)
- First posted
- 17 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will examine the independent and combined effects of creatine and carbohydrate supplementation on exercise performance, compared to placebo.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Placebo | Placebo comparator | Dietary Supplement: placebo solutionFlavored water every 20 minutes |
| Creatine monohydrate | Experimental | Dietary Supplement: Creatine MonohydrateCreatine Monohydrate supplementation every 0.5 grams every 20 minutes |
| Carbohydrate | Experimental | Dietary Supplement: CarbohydrateCarbohydrate supplementation 5 grams every 20 minutes |
| Creatine and Carbohydrate | Experimental | Dietary Supplement: Creatine Monohydrate and CarbohydrateCreatine supplementation at 0.5 gram and carbohydrate supplementation of 5 grams every 20 minutes |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- healthy (i.e. no known cardiovascular disease)
- nonsmoking
- active (regular physical activity ≥150 minutes per week of aerobic exercise and have a VO2 peak ≥35 ml/kg-min)
- a normal BMI (18.5 - 35 kg/m^2)
- between ages 18-40 years old
Key exclusion criteria (1 listed)
- previously taken creatine and/or any other dietary supplement that may interfere with exercise performance
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Creatine MonohydrateCreatine monohydrate supplementation 0.5 grams every 20 minutes | Dietary supplement | Creatine monohydrate |
| Carbohydratecarbohydrate supplementation 5 grams every 20 minutes | Dietary supplement | Carbohydrate |
| Creatine Monohydrate and CarbohydrateCreatine supplementation of 0.5 grams and carbohydrate supplementation of 5 grams every 20 minutes. | Dietary supplement | Creatine and Carbohydrate |
| placebo solutionFlavored water every 20 minutes | Dietary supplement | Placebo |
Primary outcome
Exercise Time to exhaustion
Time frame: Change in exercise time to exhaustion ( in seconds) through study completion, over the course of study completion, on average 4 weeks.
Time to exhaustion (seconds) during continuous cycling performed at 60% of each participant's maximal cycling power output following supplementation with placebo, creatine monohydrate, or creatine monohydrate plus carbohydrate.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Jul 2026.
- Individual participant dataSharing planned: Yes. IPD will be available on the Cal Poly Digital Commons website and available upon request.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Creatine Monohydrate, Carbohydrate and Creatine Monohydrate and Carbohydrate in people with Exercise Performance Recovery, run by California Polytechnic State University-San Luis Obispo at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 21 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Todd Hagobian, PhD (805-756-7511, thagobia@calpoly.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Exercise Time to exhaustion (time frame: Change in exercise time to exhaustion ( in seconds) through study completion, over the course of study completion, on average 4 weeks.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Jul 2026.