Postmenopausal BleedingNCT07707570
Hysteroscopic Findings With Histopathologic Report of Endometrium in Patients With Postmenopausal Bleeding
An observational study of Postmenopausal Bleeding, run by Sohag University.
Trial summary
To evaluate hysteroscopic findings in women with postmenopausal bleeding and correlate them with histopathological results of the endometrium., Sohag University Hospital Obstetrics and Gynecology department Read more about this study
- Who is it for?
- Ages 45 years and older, women only
- Conditions the study is for
- Postmenopausal Bleeding
- How many people
- 90 participants
- Where
- No sites listed yet
- Study dates
- 1 Aug 2026to 1 Aug 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 years and older
- Women only
- No healthy volunteers
- Adult, Older adult
Study population: All patients in this study will be subjected to the following (as detailed in the attached patient's data sheet). I. Clinical Assessment * Detailed history including: * Duration since menopause * Pattern and duration of bleeding * Obstetric and medical history * General abdominal and pelvic examination II. Transvaginal Ultrasound (TVS) * Measurement of endometrial thickness * Assessment of uterine and adnexal pathology III. Hysteroscopic Examination Hysteroscopy will be performed using a rigid hysteroscope to evaluate: * Endometrial appearance * Presence of polyps, hyperplasia, or malignancy Hysteroscopic findings will be classified as: * Normal (proliferative, secretory, atrophic) * Abnormal (polyp, hyperplasia, carcinoma, fibroid) (1,3) Criteria suggestive of: * Hyperplasia: irregular thickened endometrium, increased vascularity (1,3) * Carcinoma: irregular necrotic tissue, atypical vessels, friable surface (1,3) IV. Endometrial Sampling • Directed biopsy will be taken from su
Who may be able to join
- Postmenopausal women presenting with uterine bleeding
- Age ≥ 45 years
Who cannot join
- Women on hormone replacement therapy
- Bleeding due to vulvar, vaginal, cervical, or urethral causes
- Patients on anticoagulant therapy
- Patients unfit for hysteroscopy
- Refusal to participate
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
Mahmoud Sabri Mahmoud Mohamed Sabri Mahmoud, Resident contact
About this study
Official title: Evaluation of Hysteroscopic Findings With Histopathologic Report of Endometrium in Patients With Postmenopausal Bleeding
To evaluate hysteroscopic findings in women with postmenopausal bleeding and correlate them with histopathological results of the endometrium., Sohag University Hospital Obstetrics and Gynecology department
- Conditions
- Postmenopausal Bleeding
- Keywords
- postmenopausal
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Postmenopausal bleeding patients | * Postmenopausal women presenting with uterine bleeding * Age ≥ 45 years |
What is being measured
The primary outcome is the main question the study is designed to answer.
evaluate hysteroscopic findings in women with postmenopausal bleeding and correlate them with histopathological results of the endometrium
All patients in this study will be subjected to the following (as detailed in the attached patient's data sheet).
- Clinical Assessment
- Detailed history including:
- Duration since menopause
- Pattern and duration of bleeding
- Obstetric and medical history
- General abdominal and pelvic examination
II. Transvaginal Ultrasound (TVS)
- Measurement of endometrial thickness
- Assessment of uterine and adnexal pathology
III. Hysteroscopic Examination
Hysteroscopy will be performed using a rigid hysteroscope to evaluate:
- Endometrial appearance
- Presence of polyps, hyperplasia, or malignancy
Hysteroscopic findings will be classified as:
- Normal (proliferative, secretory, atrophic)
- Abnormal (polyp, hyperplasia, carcinoma, fibroid) (1,3)
Criteria suggestive of:
- Hyperplasia: irregular thickened endometrium, increased vascularity (1,3)
- Carcinoma: irregular necrotic tissue, atypical vessels, friable surface (1,3)
IV. Endometrial Sampling
- Directed biopsy will be taken from s
Measured: 2 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jul 2026
- Study start1 Aug 2026 (estimated)
- Primary completion1 Jan 2027 (estimated)
- Study completion1 Aug 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postmenopausal BleedingStudies of the same condition, open and under way.
- More trials run by Sohag UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 90 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sohag University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mahmoud Sabry Mahmoud, Sohag University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07707570
- Sponsor's protocol ID
- Soh-Med-26-6-28MS
- Status last verified
- Jul 2026
- First submitted
- 11 Jul 2026
- Last updated
- 16 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 16 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of Hysteroscopic Findings With Histopathologic Report of Endometrium in Patients With Postmenopausal Bleeding
- ClinicalTrials.gov ID
- NCT07707570
- Acronym / sponsor ID
- Soh-Med-26-6-28MS
- Conditions
- Postmenopausal Bleeding
- Keywords
- postmenopausal
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 90 participants (estimated)
- Lead sponsor
- Sohag UniversityUniversity, hospital or other
- Study start
- 1 Aug 2026 (estimated)
- Primary completion
- 1 Jan 2027 (estimated)
- Study completion
- 1 Aug 2027 (estimated)
- First posted
- 16 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To evaluate hysteroscopic findings in women with postmenopausal bleeding and correlate them with histopathological results of the endometrium., Sohag University Hospital Obstetrics and Gynecology department
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Postmenopausal bleeding patients | – | –* Postmenopausal women presenting with uterine bleeding * Age ≥ 45 years |
Who may qualify
- Ages
- 45 years and older
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- All patients in this study will be subjected to the following (as detailed in the attached patient's data sheet). I. Clinical Assessment * Detailed history including: * Duration since menopause * Pattern and duration of bleeding * Obstetric and medical history * General abdominal and pelvic examination II. Transvaginal Ultrasound (TVS) * Measurement of endometrial thickness * Assessment of uterine and adnexal pathology III. Hysteroscopic Examination Hysteroscopy will be performed using a rigid hysteroscope to evaluate: * Endometrial appearance * Presence of polyps, hyperplasia, or malignancy Hysteroscopic findings will be classified as: * Normal (proliferative, secretory, atrophic) * Abnormal (polyp, hyperplasia, carcinoma, fibroid) (1,3) Criteria suggestive of: * Hyperplasia: irregular thickened endometrium, increased vascularity (1,3) * Carcinoma: irregular necrotic tissue, atypical vessels, friable surface (1,3) IV. Endometrial Sampling • Directed biopsy will be taken from su
Key inclusion criteria (2 listed)
- Postmenopausal women presenting with uterine bleeding
- Age ≥ 45 years
Key exclusion criteria (5 listed)
- Women on hormone replacement therapy
- Bleeding due to vulvar, vaginal, cervical, or urethral causes
- Patients on anticoagulant therapy
- Patients unfit for hysteroscopy
- Refusal to participate
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
evaluate hysteroscopic findings in women with postmenopausal bleeding and correlate them with histopathological results of the endometrium
Time frame: 2 weeks
All patients in this study will be subjected to the following (as detailed in the attached patient's data sheet). I. Clinical Assessment * Detailed history including: * Duration since menopause * Pattern and duration of bleeding * Obstetric and medical history * General abdominal and pelvic examination II. Transvaginal Ultrasound (TVS) * Measurement of endometrial thickness * Assessment of uterine and adnexal pathology III. Hysteroscopic Examination Hysteroscopy will be performed using a rigid hysteroscope to evaluate: * Endometrial appearance * Presence of polyps, hyperplasia, or malignancy Hysteroscopic findings will be classified as: * Normal (proliferative, secretory, atrophic) * Abnormal (polyp, hyperplasia, carcinoma, fibroid) (1,3) Criteria suggestive of: * Hyperplasia: irregular thickened endometrium, increased vascularity (1,3) * Carcinoma: irregular necrotic tissue, atypical vessels, friable surface (1,3) IV. Endometrial Sampling • Directed biopsy will be taken from s
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jul 2026.
- Individual participant dataSharing planned: Undecided
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Postmenopausal Bleeding
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Mahmoud Sabri Mahmoud Mohamed Sabri Mahmoud, Resident contact
Questions about this trial
What is this clinical trial studying?
An observational study of Postmenopausal Bleeding, run by Sohag University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 16 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mahmoud Sabri Mahmoud Mohamed Sabri Mahmoud, Resident (01001264613, mahmoudsabri777014@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
evaluate hysteroscopic findings in women with postmenopausal bleeding and correlate them with histopathological results of the endometrium (time frame: 2 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jul 2026.