PreDiabetesNCT07690735
Investigation of Nutrilite Glucose Health Herbal Drink on Prediabetes Persons
A study testing Nutrilite Glucose health herbal drink in people with PreDiabetes, run by Amway (China) R&D Center at 1 site in China.
Trial summary
The goal of this two arms, randomized, double-blind controlled trial is to study whether Nutrilite herbal drink could ameliorate blood glucose level in prediabetes population. 100 eligible Participants aged 18-65 years will be enrolled in one center. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- PreDiabetes
- What is being tested?
- Nutrilite Glucose health herbal drink
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 117 participants
- Where
- 1 siteChina
- Study dates
- 4 Dec 2023to 30 May 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Male and female subjects, age 18-65 years.
- Participants who meet the following diagnostic criteria based on the "Guideline for the prevention and treatment of type 2 diabetes mellitus in China (2020 edition)" and "Guiding Principles for Evaluation of Health Food Efficacy": fasting blood glucose levels of >5.6 and <7.0 mmol/L, and/or 2-hour postprandial blood glucose levels ≥7.8 and <11.1 mmol/L.
- Participants agree not to take any dietary supplements or foods for blood glucose controlduring the study.
- Participants understand the test procedure, read, and sign an appropriate Informed Consent Form indicating their willingness to participate.
Who cannot join
- Participants diagnosed with type 1 diabetes mellitus.
- Malignant diseases: patients with severe lung, cardiovascular, blood and hematopoietic system, central nervous system or other system diseases, as well as tumor patients
- Participants who developed diabetic ketosis, acidosis, and infection within the past 3 months.
- Participants who participated in other clinical trials within the past 3 months.
- Women who are pregnant or breastfeeding, or who plan to become pregnant during the trial;
- Participantes who are allergic to the test samples.
- PI considers that volunteers cannot fully cooperate with the trial arrangement.
Trial locations and contacts
1 site in 1 country.
China1 site
Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine
Beijing
About this study
Official title: A Randomized, Double-blind Controlled Trial to Investigate the Effects of Nutrilite Glucose Health Herbal Drink on Prediabetes Persons
The goal of this two arms, randomized, double-blind controlled trial is to study whether Nutrilite herbal drink could ameliorate blood glucose level in prediabetes population.
100 eligible Participants aged 18-65 years will be enrolled in one center. Participants will be randomly assigned to two study groups, with 50 subjects in each group.Study subjects will be administrated with either the Nutrilite product or a placebo drink for two months (8 weeks). And up to three study visits will be made by the subject over a 2-month period intervention.
Researchers will compare two groups to see if consumption of Nutrilite herbal drink could significantly ameliorate blood glucose level at the end of the study.
- Conditions
- PreDiabetes
- Being tested
- Nutrilite Glucose health herbal drink, Placebo drink
- Medical subject headings
- Prediabetic State
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nutrilite Glucose health herbal drinkDietary supplement
1 sachet per time, 3 times a day after meal
Placebo drinkDietary supplement
1 sachet per time, 3 times a day after meal
| Study group | Role | What they receive |
|---|---|---|
| nutrilite glucose health herbal drink | Experimental | Not described Receives: Dietary Supplement: Nutrilite Glucose health herbal drink |
| placebo drink | Placebo comparator | Not described Receives: Dietary Supplement: Placebo drink |
What is being measured
The primary outcome is the main question the study is designed to answer.
Changes in blood glucose level（fasten plasma glucose）
fasten plasma glucose
Measured: baseline day 0, day 56
Changes in blood glucose level (2-hour postprandial blood glucose levels)
2-hour postprandial blood glucose levels
Measured: baseline day 0, day 56
Secondary outcomes (6)
changes of glycated hemoglobin
HbA1c level
Measured: baseline day 0, day 56
Changes in islet function (insulin level)
insulin level
Measured: baseline day 0, day 56
changes in islet function (C-peptide level)
C-peptide level
Measured: baseline day 0, day 56
Changes in blood lipids profile (TC)
Total cholesterol
Measured: baseline day 0, day 56
Changes in blood lipids profile (TG)
total triglycerides
Measured: baseline day 0, day 56
Symptom observation
A clinical symptom scoring scale for abnormal glucose metabolism was formulated with reference to Internal Medicine of Traditional Chinese Medicine. Symptoms were scored by mild, moderate and severe grades. Total scores were recorded before and after the trial food administration to calculate the clinical symptom improvement rate. The main observed clinical symptoms include excessive thirst with frequent drinking, polyphagia with easy hunger, frequent micturition and other related manifestations.
Measured: baseline day 0, day 56
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Jul 2026
- Study start4 Dec 2023
- Primary completion30 Apr 2026
- Study completion30 May 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for PreDiabetesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 117 participants (actual)
Sponsor and investigators
- Lead sponsor
- Amway (China) R&D Center
- Sponsor type
- Industry (pharma, biotech, devices)
- Collaborators
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07690735
- Sponsor's protocol ID
- IS20220010RDBJSP02V1
- Status last verified
- Jul 2026
- First submitted
- 30 Nov 2023
- Last updated
- 8 Jul 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 8 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Randomized, Double-blind Controlled Trial to Investigate the Effects of Nutrilite Glucose Health Herbal Drink on Prediabetes Persons
- ClinicalTrials.gov ID
- NCT07690735
- Acronym / sponsor ID
- IS20220010RDBJSP02V1
- Conditions
- PreDiabetes
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 117 participants (actual)
- Lead sponsor
- Amway (China) R&D CenterIndustry (pharma, biotech, devices)
- Collaborators
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
- Study start
- 4 Dec 2023 (actual)
- Primary completion
- 30 Apr 2026 (actual)
- Study completion
- 30 May 2026 (actual)
- First posted
- 8 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this two arms, randomized, double-blind controlled trial is to study whether Nutrilite herbal drink could ameliorate blood glucose level in prediabetes population.
100 eligible Participants aged 18-65 years will be enrolled in one center. Participants will be randomly assigned to two study groups, with 50 subjects in each group.Study subjects will be administrated with either the Nutrilite product or a placebo drink for two months (8 weeks). And up to three study visits will be made by the subject over a 2-month period intervention.
Researchers will compare two groups to see if consumption of Nutrilite herbal drink could significantly ameliorate blood glucose level at the end of the study.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| nutrilite glucose health herbal drink | Experimental | Dietary Supplement: Nutrilite Glucose health herbal drink |
| placebo drink | Placebo comparator | Dietary Supplement: Placebo drink |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Male and female subjects, age 18-65 years.
- Participants who meet the following diagnostic criteria based on the "Guideline for the prevention and treatment of type 2 diabetes mellitus in China (2020 edition)" and "Guiding Principles for Evaluation of Health Food Efficacy": fasting blood glucose levels of >5.6 and <7.0 mmol/L, and/or 2-hour postprandial blood glucose levels ≥7.8 and <11.1 mmol/L.
- Participants agree not to take any dietary supplements or foods for blood glucose controlduring the study.
- Participants understand the test procedure, read, and sign an appropriate Informed Consent Form indicating their willingness to participate.
Key exclusion criteria (7 listed)
- Participants diagnosed with type 1 diabetes mellitus.
- Malignant diseases: patients with severe lung, cardiovascular, blood and hematopoietic system, central nervous system or other system diseases, as well as tumor patients
- Participants who developed diabetic ketosis, acidosis, and infection within the past 3 months.
- Participants who participated in other clinical trials within the past 3 months.
- Women who are pregnant or breastfeeding, or who plan to become pregnant during the trial;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Nutrilite Glucose health herbal drink1 sachet per time, 3 times a day after meal | Dietary supplement | nutrilite glucose health herbal drink |
| Placebo drink1 sachet per time, 3 times a day after meal | Dietary supplement | placebo drink |
Primary outcome
Changes in blood glucose level（fasten plasma glucose）
Time frame: baseline day 0, day 56
fasten plasma glucose
Changes in blood glucose level (2-hour postprandial blood glucose levels)
Time frame: baseline day 0, day 56
2-hour postprandial blood glucose levels
6 secondary outcomes
changes of glycated hemoglobin
Time frame: baseline day 0, day 56
Changes in islet function (insulin level)
Time frame: baseline day 0, day 56
changes in islet function (C-peptide level)
Time frame: baseline day 0, day 56
Changes in blood lipids profile (TC)
Time frame: baseline day 0, day 56
Changes in blood lipids profile (TG)
Time frame: baseline day 0, day 56
Symptom observation
Time frame: baseline day 0, day 56
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Jul 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Nutrilite Glucose health herbal drink in people with PreDiabetes, run by Amway (China) R&D Center at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Changes in blood glucose level（fasten plasma glucose） (time frame: baseline day 0, day 56). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jul 2026.