Quality of LifeNCT07681037
The Impact of Good Versus Poor Sleep Quality on Quality of Life, Depression, and Fatigue in Individuals With Multiple Sclerosis
An observational study of Quality of Life and Depression, run by Trakya University at 1 site in Turkey (Türkiye).
Trial summary
This cross-sectional study was conducted to examine the effects of good and poor sleep quality on quality of life, depression, and fatigue in individuals with multiple sclerosis. Read more about this study
- Who is it for?
- Ages 18 to 80 years
- Conditions the study is for
- Quality of Life, Depression, Multiple Sclerosis
- How many people
- 121 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Jul 2025to 5 Jan 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Having a confirmed diagnosis of multiple sclerosis
Who may be able to join
- Being over 18 years of age
- Having a confirmed diagnosis of multiple sclerosis
- Being a registered patient at a multiple sclerosis clinic
- Not experiencing communication difficulties
- Volunteering to participate in the study
Who cannot join
- Being under 18 years of age
- Not having a confirmed diagnosis of multiple sclerosis
- Not currently attending a multiple sclerosis clinic
- Experiencing communication difficulties
- Not volunteering to participate in the study
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Trakya University Faculty of Medicine Dean'S Office Building
Merkez, Edirne, 22100
About this study
Official title: Multiple Sklerozlu Bireylerde Iyi Uyku Kalitesi ve kötü Uyku Kalitesinin yaşam Kalitesi, Depresyon ve Yorgunluk üzerine Etkisi
This cross-sectional study was conducted to examine the effects of good and poor sleep quality on quality of life, depression, and fatigue in individuals with multiple sclerosis.
The study was conducted at the Multiple Sclerosis (n=121) Outpatient Clinic of the Health Research and Application Center at the Trakya University between July 15, 2025, and December 30, 2025, with patients who were receiving outpatient treatment, had no communication difficulties, and agreed to participate in the study. These patients were provided with an "Informed Consent Form" "Pittsburgh Sleep Quality Index," "SF-12 Quality of Life Scale," "Beck Depression Scale," and "Fatigue Impact Scale." Participants were informed about the purpose of the study, and if they agreed to participate, they were asked to complete the questionnaire forms.
Read the detailed description
Sleep disorders are common among individuals with multiple sclerosis and negatively impact their physical and psychological well-being. This study was conducted to examine the effects of good and poor sleep quality on quality of life, depression, and fatigue in individuals with multiple sclerosis.
Material and Methods: The study was conducted between july 15, 2025 and December 30, 2025 with 121 patients diagnosed with Multiple Sclerosis at the Neurology outpatient clinic of a university hospital in Edirne. Data were collected using "Patient Information Form" "Pittsburgh Sleep Quality Index," "SF-12 Quality of Life Scale," "Beck Depression Scale," and "Fatigue Impact Scale." Participants were informed about the purpose of the study, and if they agreed to participate, they were asked to complete the questionnaire forms.
Financial Support: The present study was supported by the Research Fund of Trakya University. Project No: 2025/278
- Conditions
- Quality of Life, Depression, Multiple Sclerosis
- Keywords
- Fatigue, Depression, Quality of life, Multiple Sclerosis, Sleep Quality
- Medical subject headings
- Depression, Multiple Sclerosis, Fatigue, Sleep Initiation and Maintenance Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Multiple Sclerosis | Data were collected using a patient Information Form, the Pittsburgh Sleep Quality Index (PSQI), the |
What is being measured
The primary outcome is the main question the study is designed to answer.
determining sleep quality
To evaluate the association between sleep quality and quality of life, depression, and fatigue in individuals with multiple sclerosis.
Measured: 6 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Jul 2026
- Study start15 Jul 2025
- Primary completion30 Dec 2025
- Study completion5 Jan 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Quality of LifeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 121 participants (actual)
Sponsor and investigators
- Lead sponsor
- Trakya University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, AYFER GUNES, Trakya University
- Investigators
- Ayfer Gunes, Principal investigator, Trakya University Medical Research and Application Centre, Department of Neurology
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07681037
- Sponsor's protocol ID
- 2025/278
- Status last verified
- Jun 2026
- First submitted
- 10 Jun 2026
- Last updated
- 2 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 2 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Multiple Sklerozlu Bireylerde Iyi Uyku Kalitesi ve kötü Uyku Kalitesinin yaşam Kalitesi, Depresyon ve Yorgunluk üzerine Etkisi
- ClinicalTrials.gov ID
- NCT07681037
- Acronym / sponsor ID
- 2025/278
- Conditions
- Quality of Life, Depression, Multiple Sclerosis
- Keywords
- Fatigue, Depression, Quality of life, Multiple Sclerosis, Sleep Quality
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 121 participants (actual)
- Lead sponsor
- Trakya UniversityUniversity, hospital or other
- Study start
- 15 Jul 2025 (actual)
- Primary completion
- 30 Dec 2025 (actual)
- Study completion
- 5 Jan 2026 (actual)
- First posted
- 2 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This cross-sectional study was conducted to examine the effects of good and poor sleep quality on quality of life, depression, and fatigue in individuals with multiple sclerosis.
The study was conducted at the Multiple Sclerosis (n=121) Outpatient Clinic of the Health Research and Application Center at the Trakya University between July 15, 2025, and December 30, 2025, with patients who were receiving outpatient treatment, had no communication difficulties, and agreed to participate in the study. These patients were provided with an "Informed Consent Form" "Pittsburgh Sleep Quality Index," "SF-12 Quality of Life Scale," "Beck Depression Scale," and "Fatigue Impact Scale." Participants were informed about the purpose of the study, and if they agreed to participate, they were asked to complete the questionnaire forms.
Detailed description
Sleep disorders are common among individuals with multiple sclerosis and negatively impact their physical and psychological well-being. This study was conducted to examine the effects of good and poor sleep quality on quality of life, depression, and fatigue in individuals with multiple sclerosis.
Material and Methods: The study was conducted between july 15, 2025 and December 30, 2025 with 121 patients diagnosed with Multiple Sclerosis at the Neurology outpatient clinic of a university hospital in Edirne. Data were collected using "Patient Information Form" "Pittsburgh Sleep Quality Index," "SF-12 Quality of Life Scale," "Beck Depression Scale," and "Fatigue Impact Scale." Participants were informed about the purpose of the study, and if they agreed to participate, they were asked to complete the questionnaire forms.
Financial Support: The present study was supported by the Research Fund of Trakya University. Project No: 2025/278
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Multiple Sclerosis | – | –Data were collected using a patient Information Form, the Pittsburgh Sleep Quality Index (PSQI), the |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Having a confirmed diagnosis of multiple sclerosis
Key inclusion criteria (5 listed)
- Being over 18 years of age
- Having a confirmed diagnosis of multiple sclerosis
- Being a registered patient at a multiple sclerosis clinic
- Not experiencing communication difficulties
- Volunteering to participate in the study
Key exclusion criteria (5 listed)
- Being under 18 years of age
- Not having a confirmed diagnosis of multiple sclerosis
- Not currently attending a multiple sclerosis clinic
- Experiencing communication difficulties
- Not volunteering to participate in the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
determining sleep quality
Time frame: 6 month
To evaluate the association between sleep quality and quality of life, depression, and fatigue in individuals with multiple sclerosis.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Jul 2026.
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Ayfer Gunes principal investigator
Trakya University Medical Research and Application Centre, Department of Neurology
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Quality of Life and Depression, run by Trakya University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
determining sleep quality (time frame: 6 month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Jul 2026.