Omega-3 Fatty AcidsNCT07665918
Evaluation of OMEGA-3 Effect in Alveolar Socket Preservation in Aesthetic Zone
A study testing Omega 3 Fish Oil supplements in people with Omega-3 Fatty Acids and Socket Preservation, run by Cairo University at 1 site in Egypt.
Trial summary
To evaluate the effect of Omega-3 in preserving bone after extraction Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Omega-3 Fatty Acids, Socket Preservation, Esthetic Zone
- What is being tested?
- Omega 3 Fish Oil supplements
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 10 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jan 2025to 25 Oct 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Patients with non-restorable remaining roots.
- Patients free of systemic conditions that might affect the surgical procedure or the quantity or quality of bone (uncontrolled hypertension, uncontrolled diabetes).
Who cannot join
- Patients below 18 years old
- Patients with hypersensitivity to omega-3, drug formulations or allergic to seafood.
- Pregnant or lactating females
- Patients undergoing chemotherapy or radiotherapy
- Smokers
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Evaluation of OMEGA-3 Effect in Alveolar Socket Preservation in Aesthetic Zone: A Case Series
To evaluate the effect of Omega-3 in preserving bone after extraction
Read the detailed description
The evaluation of the effect of omega-3 on the bone of the socket with changes in the dimensions like vertical and horizontal bone changes 3months after extraction .
- Conditions
- Omega-3 Fatty Acids, Socket Preservation, Esthetic Zone
- Being tested
- Omega 3 Fish Oil supplements
- Keywords
- Omega-3, Socket preservation, Atraumatic extraction, Esthetic zone, Extraction socket, Implant
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Omega 3 Fish Oil supplementsDietary supplement
Also called Omega-3
omega-3 fatty acid supplement
| Study group | Role | What they receive |
|---|---|---|
| Atraumatic extraction for single rooted teeth and placement of omega-3 in the socket | Experimental | Atraumatic extraction for single rooted teeth in anterior zone and omega-3 polyunsaturated fatty acid placed with collagen sponge inside the extraction socket for socket preservation and implant placement Receives: Dietary Supplement: Omega 3 Fish Oil supplements |
What is being measured
The primary outcome is the main question the study is designed to answer.
Post-operative pain
Visual Analogue Scale score "VAS score" From 0-10 scores score 0 is no pain which is the best 1-4 is mild pain 5 is moderate pain from 5 -10 pain is getting worse and 10 is the worst
Measured: immediately after extraction and the second day after extraction
Secondary outcomes (5)
Radiographic bone changes "horizontal bone changes " using Cone beam CBCT
Performing one CBCT before extraction and one new CBCT after 3 months of extraction and omega-3 placement then comparing both CBCTs by J image computer program to get the difference in vertical bone measurements in millimeter
Measured: before extraction and 3months after omega 3 placement
Radiographic bone changes " Vertical bone fill" using CBCT
Performing one CBCT before extraction and one new CBCT after 3 months of extraction and omega-3 placement then comparing both CBCTs by J image computer program to get the difference in vertical bone measurements in millimeter
Measured: before and after 3 months of extraction and omega-3 placement
Radiographic bone changes "Bone density" using CBCT
Performing one CBCT before extraction and one new CBCT after 3 months of extraction and omega-3 placement then comparing both CBCTs by J image computer program to get the radiographic bone changes in millimeter and Hounsfield units
Measured: 3 months after extraction and placement of omega-3
Histological examination
using Hematoxylin and Eosin staining to measure the area of newly formed bone "Percentage"
Measured: after 3months of extraction during implant placement bone is taken using trephine bur
Healing Index "HI" by Landry et al using scores
Using Landry et al wound healing index to measure soft tissue reaction changes. Each category is scored from 1 to 5, with 1 indicating very poor healing and 5 indicating excellent healing. The HI is a useful tool for assessing the quality of wound healing and guiding postoperative interventions.
Measured: after 3months of omega 3 placement
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Jun 2026
- Study start1 Jan 2025
- Primary completion24 Oct 2025
- Study completion25 Oct 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Omega-3 Fatty AcidsStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 10 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Salma Khaled Elmetwally, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07665918
- Sponsor's protocol ID
- 30122024
- Status last verified
- Jun 2026
- First submitted
- 27 May 2026
- Last updated
- 24 Jun 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of OMEGA-3 Effect in Alveolar Socket Preservation in Aesthetic Zone: A Case Series
- ClinicalTrials.gov ID
- NCT07665918
- Acronym / sponsor ID
- 30122024
- Conditions
- Omega-3 Fatty Acids, Socket Preservation, Esthetic Zone
- Keywords
- Omega-3, Socket preservation, Atraumatic extraction, Esthetic zone, Extraction socket, Implant
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 10 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Jan 2025 (actual)
- Primary completion
- 24 Oct 2025 (actual)
- Study completion
- 25 Oct 2025 (actual)
- First posted
- 24 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To evaluate the effect of Omega-3 in preserving bone after extraction
Detailed description
The evaluation of the effect of omega-3 on the bone of the socket with changes in the dimensions like vertical and horizontal bone changes 3months after extraction .
Study design
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Atraumatic extraction for single rooted teeth and placement of omega-3 in the socket | Experimental | Dietary Supplement: Omega 3 Fish Oil supplementsAtraumatic extraction for single rooted teeth in anterior zone and omega-3 polyunsaturated fatty acid placed with collagen sponge inside the extraction socket for socket preservation and implant placement |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Patients with non-restorable remaining roots.
- Patients free of systemic conditions that might affect the surgical procedure or the quantity or quality of bone (uncontrolled hypertension, uncontrolled diabetes).
Key exclusion criteria (5 listed)
- Patients below 18 years old
- Patients with hypersensitivity to omega-3, drug formulations or allergic to seafood.
- Pregnant or lactating females
- Patients undergoing chemotherapy or radiotherapy
- Smokers
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Omega 3 Fish Oil supplementsAlso: Omega-3omega-3 fatty acid supplement | Dietary supplement | Atraumatic extraction for single rooted teeth and placement of omega-3 in the socket |
Primary outcome
Post-operative pain
Time frame: immediately after extraction and the second day after extraction
Visual Analogue Scale score "VAS score" From 0-10 scores score 0 is no pain which is the best 1-4 is mild pain 5 is moderate pain from 5 -10 pain is getting worse and 10 is the worst
5 secondary outcomes
Radiographic bone changes "horizontal bone changes " using Cone beam CBCT
Time frame: before extraction and 3months after omega 3 placement
Radiographic bone changes " Vertical bone fill" using CBCT
Time frame: before and after 3 months of extraction and omega-3 placement
Radiographic bone changes "Bone density" using CBCT
Time frame: 3 months after extraction and placement of omega-3
Histological examination
Time frame: after 3months of extraction during implant placement bone is taken using trephine bur
Healing Index "HI" by Landry et al using scores
Time frame: after 3months of omega 3 placement
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Jun 2026.
- Polyunsaturated fatty acids and its effect on inflammationLink provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Omega 3 Fish Oil supplements in people with Omega-3 Fatty Acids and Socket Preservation, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 24 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Post-operative pain (time frame: immediately after extraction and the second day after extraction). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Jun 2026.