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Hamstring MusclesEMG-BFNCT07660926

Optimizing Hamstring Activation Through EMG-Feedback and the Hamshell Device

A study testing EMG-Biofeedback-Training in people with Hamstring Muscles and Hamstring Muscle Strength, run by Praxisklinik Rennbahn AG at 1 site in Switzerland.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

In this study, we investigate whether training of the posterior thigh muscles with visual feedback on muscle activity is more effective than the same training without feedback. To this end, healthy, physically active adults complete a training programme on a training device twice a week for five weeks. Read more about this study

Who is it for?
Ages 18 to 40 yearsHealthy volunteers can take part
Conditions the study is for
Hamstring Muscles, Hamstring Muscle Strength
What is being tested?
EMG-Biofeedback-Training
Could I receive a placebo?
No, everyone receives an active treatment
How many people
50 participants
Where
1 siteSwitzerland
Study dates
9 Jun 2026to 31 Jul 2027
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 40 years
  • All sexes
  • Healthy volunteers accepted
  • Adult

Who may be able to join

  • Age between 18 and 40 years
  • Recreationally active, defined as engaging in at least 150 minutes per week of moderate-intensity physical activity

Who cannot join

  • Current or recent (≤6 months) musculoskeletal injury of the lower extremities
  • Inability to follow study procedures or instructions

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Switzerland1 site, 1 recruiting
  • Rennbahnklinik

    Muttenz, 4132

    Jan Stutz, PhD, +41 61 465 64 88, research@rennbahnklinik.ch

    Recruiting

Other trials in Switzerland

About this study

In this study, we investigate whether training of the posterior thigh muscles with visual feedback on muscle activity is more effective than the same training without feedback. To this end, healthy, physically active adults complete a training programme on a training device twice a week for five weeks. Muscle strength, muscle activity, and flexibility are measured before and after the training. Participants are randomly assigned to one of two groups: one group trains with feedback on muscle activity, the other without. Participation involves minimal risks, similar to those of a typical strength training session (e.g. muscle soreness). The aim of the study is to improve training methods for the prevention of muscle injuries.

Read the detailed description

Hamstring injuries represent a significant burden in both recreational and competitive sports. Conventional hamstring training programmes primarily target muscle strength and hypertrophy. Despite generally positive outcomes, individual responses to strength-focused interventions vary considerably, suggesting that improvements in strength alone may not fully account for reductions in injury risk. Neuromuscular control and movement quality - factors likely relevant to hamstring injury risk - are not explicitly addressed in most traditional training protocols.

The Nordic hamstring exercise (NHE) is frequently used in clinical and sports practice, but presents biomechanical limitations, particularly with regard to loading at extended knee angles. The Hamshell device has been developed to address these limitations by enabling hamstring-specific loading across a broader range of knee angles.

Electromyographic (EMG) biofeedback is a technique in which real-time information about muscle electrical activity is provided to the user during exercise. This approach has been shown to enhance voluntary muscle activation and neuromuscular control in various rehabilitation and training contexts. Combining EMG biofeedback with Hamshell-based training may therefore optimise neuromuscular adaptations beyond what can be achieved with resistance training alone.

Study Design

This is a single-centre, prospective, randomised controlled intervention study with a parallel-group design, conducted at the Praxisklinik Rennbahn AG in Muttenz, Switzerland.

Participants

50 recreationally active adults (aged 18-40 years), defined as engaging in at least 150 minutes per week of moderate-intensity physical activity. Individuals with a current or recent (≤ 6 months) musculoskeletal injury of the lower extremities, or who are unable to follow study procedures, are excluded. Participants are randomly assigned in a 1:1 ratio to the intervention or control group (n = 25 per group).

Intervention

Both groups complete 10 training sessions over 5 weeks (twice per week), each lasting approximately 30 minutes, at the study centre. Sessions consist of hamstring and gluteus maximus exercises performed at extended knee angles using the Hamshell device. The first and middle sessions are supervised to ensure correct exercise technique and appropriate progression; EMG is recorded during these supervised sessions.

The intervention group receives real-time visual EMG biofeedback during all training sessions, aimed at optimising biceps femoris and gluteus maximus activation. The control group performs the identical training programme without any biofeedback.

Assessments

Participants undergo baseline (T0) and post-intervention (T1) assessments, each comprising:

  • Hamstring flexibility testing
  • Countermovement jumps (CMJ) with simultaneous EMG recording of the biceps femoris and gluteus maximus
  • Three maximal voluntary contractions (MVCs) of the same muscles on the Hamshell device
  • Isokinetic strength testing of knee flexors and extensors in concentric and eccentric modes at 30°/s and 150°/s, and isometrically (0°/s), with concurrent EMG recording

Training adherence and session ratings of perceived exertion (RPE) are recorded for all sessions.

Primary Endpoint

Integrated EMG (iEMG) activity of the biceps femoris during the modified Nordic hamstring exercise, assessed at post-intervention (T1).

Secondary Endpoints

  • Hamstring and quadriceps strength (isokinetic dynamometry, concentric and eccentric modes at 0°/s, 30°/s, and 150°/s) with concurrent EMG recording of the biceps femoris and gluteus maximus
  • Hamstring flexibility
  • EMG activity of the biceps femoris and gluteus maximus during the eccentric phase of the CMJ
  • Functional performance (CMJ vertical impulse)
  • Training adherence and session RPE

Statistical Analysis

Primary and secondary endpoints will be analysed using analysis of covariance (ANCOVA), with post-intervention values as the dependent variable, group allocation as the fixed factor, and corresponding baseline values as covariates.

Sample Size

A sample size of 25 participants per group (50 total) provides ≥ 80% power to detect a standardised mean difference of d = 0.81 (based on between-group iEMG differences reported by Croce et al.), at a two-sided significance level of α = 0.05.

Study Duration

The estimated duration of the main investigational period is approximately 12 months (First-Participant-In: June 2026; Last-Participant-Out: May 2027).

Being tested
EMG-Biofeedback-Training, Control
Keywords
Hamstring, Training, Biofeedback, EMG

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • EMG-Biofeedback-TrainingBehavioural

    Participants complete 10 training sessions with EMG feedback over a 5-week period. The training is designed to optimize biceps femoris and gluteus maximus activation at extended knee angles using the Hamshell device. All training sessions last approximately 30 minutes and are conducted at the Rennbahnklinik. The first and middle training sessions are supervised to ensure correct exercise execution and appropriate progression. During these supervised session, EMG will be recorded.

  • ControlBehavioural

    Particpants in the control group will perform the same training as the intervention group but without EMG feedback.

Study groups in NCT07660926
Study groupRoleWhat they receive
EMG-BiofeedbackExperimentalParticipants in this arm complete 10 training sessions with EMG feedback over a 5-week period. The training is designed to optimize biceps femoris and gluteus maximus activation at extended knee angles using the Hamshell device. All training sessions last approximately 30 minutes and are conducted at the Rennbahnklinik. The first and middle training sessions are supervised to ensure correct exercise execution and appropriate progression. During these supervised session, EMG will be recorded.
Receives: Behavioral: EMG-Biofeedback-Training
ControlActive comparatorParticpants in the control group will perform the same training as the intervention group but without EMG feedback.
Receives: Behavioral: Control

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. iEMG biceps femoris during a modified Nordic Hamstring Exercise

    Integrated EMG activity of the biceps femoris (BF) muscle during the modified version of the Nordic Hamstring Exercise.

    Measured: Before and after the 5-week intervention period

Secondary outcomes (4)
  1. Hamstring and quadriceps strength

    Hamstring and quadriceps strength (isokinetic dynamometry, concentric and eccentric modes at 0°/s, 30°/s, and 150°/s) with concurrent EMG recording of the biceps femoris and gluteus maximus

    Measured: Before and after the 5-week intervention period

  2. Hamstring flexibility

    Hamstring flexibility assessed with the passive knee extension test

    Measured: Before and after the 5-week intervention period

  3. EMG biceps femoris

    EMG activity of the biceps femoris and gluteus maximus during the eccentric phase of the CMJ

    Measured: Before and after the 5-week intervention period

  4. Functional performance

    Functional performance (CMJ vertical impulse)

    Measured: Before and after the 5-week intervention period

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted22 Jun 2026
  2. Study start9 Jun 2026
  3. Primary completion30 Jun 2027 (estimated)
  4. Study completion31 Jul 2027 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Basic science
Allocation
Randomised
Intervention model
Parallel groups
Masking
None (open label)
Enrolment
50 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07660926
Sponsor's protocol ID
EMG-BF
Other IDs
68158
Acronym
EMG-BF
Status last verified
Jun 2026
First submitted
9 Jun 2026
Last updated
22 Jun 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Undecided

Questions about this trial

What is this clinical trial studying?

A study testing EMG-Biofeedback-Training in people with Hamstring Muscles and Hamstring Muscle Strength, run by Praxisklinik Rennbahn AG at 1 site in Switzerland.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 22 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Jan Stutz, PhD (+41 61 465 64 88, research@rennbahnklinik.ch), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

iEMG biceps femoris during a modified Nordic Hamstring Exercise (time frame: Before and after the 5-week intervention period). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Jun 2026; AzTrials last refreshed its copy on 27 Oct 2026.

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