Lung UltrasoundNCT07654153
Surgical Positions and Postoperative Atelectasis: A Lung Ultrasound Study
An observational study of Lung Ultrasound and Atelectasis, run by Cumhuriyet University at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study is to prospectively evaluate the effect of surgical position on the development of postoperative atelectasis in patients undergoing surgery in supine, prone, lateral decubitus, and lithotomy positions using lung ultrasonography (LUS), and to investigate whether there is a difference between these… Read more about this study
- Who is it for?
- Ages 18 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Lung Ultrasound, Atelectasis
- What is being tested?
- lung ultrasound
- Type of treatment
- Surgery or procedure
- How many people
- 100 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 20 Jul 2026to 1 Aug 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: The study will include a total of 100 patients in 4 groups, aged 18-65 years, with an ASA (American Society of Anesthesiologists) physical status between I and III, who are scheduled to undergo general anesthesia in supine, prone, lateral decubitus, and lithotomy positions.
Who may be able to join
- Being between 18-80 years of age
- Having ASA I-III status
- Planning elective surgery under general anesthesia
- Agreeing to participate in the study and signing the consent form
Who cannot join
- Patients requiring emergency surgery
- Patients with ASA IV or higher
- Presence of a known serious preoperative lung disease (COPD, Asthma, Pneumonia, Pleural effusion, Pneumothorax, Interstitial lung disease, Bronchiectasis, etc.)
- History of neuromuscular disease
- Body Mass Index (BMI) > 35 kg/m² (Morbid obesity)
- Presence of chest wall deformity or skin lesions that would obstruct LUS imaging
Show all 13Show fewer
- Cases with an operative duration of less than 60 minutes or more than 300 minutes
- Patients with a history of thoracotomy, sternotomy, or prior open thoracic surgery
- Patients with alcohol or drug dependence
- Patients with significant anemia
- Patients who are pregnant or lactating
- Patients who develop laryngospasm following extubation
- Refusal to provide consent or inability to cooperate
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Sivas Cumhuriyet University
Sivas, Sivas, 58140
oğuz gündoğdu, +905545945469, droguzgundogdu@gmail.com
About this study
Official title: Evaluation of the Effect of Surgical Positions Under General Anesthesia on Postoperative Atelectasis Using Lung Ultrasonography
The aim of this study is to prospectively evaluate the effect of surgical position on the development of postoperative atelectasis in patients undergoing surgery in supine, prone, lateral decubitus, and lithotomy positions using lung ultrasonography (LUS), and to investigate whether there is a difference between these positions.
Read the detailed description
Study Groups: Patients will be divided into 4 groups according to the surgical position to be given during the operation:
- Group 1 (Supine, n=25)
- Group 2 (Prone, n=25)
- Group 3 (Lateral Decubitus, n=25)
- Group 4 (Lithotomy, n=25) All patients will receive standard anesthesia induction and maintenance with 1 mcg/kg fentanyl citrate, 2 mg/kg propofol, 0.6 mg/kg rocuronium intravenously, followed by maintenance with desfluran at a MAC of 0.8-1.2 (if necessary). Patient demographic data (age, gender, height, weight, BMI, ASA score, comorbidities) and intraoperative data (heart rate, SpO2, mean arterial pressure, duration of surgery, surgical position, applied PEEP level) will be recorded.
Lung Ultrasonography (LUS) Protocol: LUS evaluation, Dr. The ultrasound will be performed by Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe]. LUS will be performed using a 12-zone protocol consisting of 6 standard zones (upper and lower quadrants of the anterior, lateral, and posterior regions) for both hemithoraxes. The evaluation will be performed at 3 different time points:
- Preoperative (T0): Immediately before anesthesia induction, in the supine position (Baseline).
- Postoperative (T1): Immediately before the patient is awakened, in the supine position.
- Postoperative (T2): 20 minutes after the patient is transferred to the PACU. MLUS Scoring: Each region will be scored between 0-3 according to lung ventilation (MLUS Score):
- 0 Points: Normal ventilation (presence of A-line, fewer than 3 B-lines)
- 1 Point: Minor ventilation loss (≥ 3 B-lines or subpleural consolidations ≤ 1 cm in diameter separated by a normal pleural line)
- 2 Points: Moderate ventilation loss (Multiple small subpleural consolidations ≤ 1 cm in diameter separated by multiple and converging B-lines or a thickened/irregular pleural line)
- 3 Points: Severe ventilation loss (At least one consolidation > 1 cm in diameter or subpleural consolidations > 1x2 cm in diameter) The total MLUS score will be obtained by summing the scores of the 12 regions (Minimum 0, Maximum 36). Atelectasis will be defined as "predisposition to atelectasis when each quadrant score is 2 or 3".
- Conditions
- Lung Ultrasound, Atelectasis
- Being tested
- lung ultrasound
- Keywords
- lung ultrasound
- Medical subject headings
- Pulmonary Atelectasis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
lung ultrasoundProcedure or surgery
Lung Ultrasound (LUS) Protocol: The LUS evaluation will be performed by Dr. Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe]
| Study group | Role | What they receive |
|---|---|---|
| Group 1 | Supine position Receives: Procedure: lung ultrasound | |
| group 2 | prone position Receives: Procedure: lung ultrasound | |
| group 3 | lateral decubitus Receives: Procedure: lung ultrasound | |
| Group 4 | lithotomy Receives: Procedure: lung ultrasound |
What is being measured
The primary outcome is the main question the study is designed to answer.
Modified Lung Ultrasound Score
MLUS Scoring: Each region will be scored between 0-3 according to lung ventilation (MLUS Score):
- 0 Points: Normal ventilation (presence of A-line, fewer than 3 B-lines)
- 1 Point: Minor ventilation loss (≥ 3 B-lines or subpleural consolidations ≤ 1 cm in diameter separated by a normal pleural line)
- 2 Points: Moderate ventilation loss (Multiple small subpleural consolidations ≤ 1 cm in diameter separated by multiple and converging B-lines or a thickened/irregular pleural line)
- 3 Points: Severe ventilation loss (At least one consolidation > 1 cm in diameter or subpleural consolidations > 1x2 cm in diameter) The total MLUS score will be obtained by summing the scores of the 12 regions (Minimum 0, Maximum 36). Atelectasis will be defined as "predisposition to atelectasis when each quadrant score is 2 or 3"
Measured: 1. (T0):Immediately before anesthesia induction, in the supine position 2.(T1): Immediately before the patient is awakened, in the supine posit 3.(T2):Twenty minutes after the patient was admitted to the PACU (Post-Anesthesia Care Unit)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jun 2026
- Study start20 Jul 2026 (estimated)
- Primary completion20 Jun 2027 (estimated)
- Study completion1 Aug 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Lung UltrasoundStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Prospective
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cumhuriyet University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Oguz Gundogdu, Cumhuriyet University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07654153
- Sponsor's protocol ID
- 2025-11/01
- Status last verified
- Jul 2026
- First submitted
- 12 Jun 2026
- Last updated
- 21 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of the Effect of Surgical Positions Under General Anesthesia on Postoperative Atelectasis Using Lung Ultrasonography
- ClinicalTrials.gov ID
- NCT07654153
- Acronym / sponsor ID
- 2025-11/01
- Conditions
- Lung Ultrasound, Atelectasis
- Keywords
- lung ultrasound
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Cumhuriyet UniversityUniversity, hospital or other
- Study start
- 20 Jul 2026 (estimated)
- Primary completion
- 20 Jun 2027 (estimated)
- Study completion
- 1 Aug 2027 (estimated)
- First posted
- 17 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to prospectively evaluate the effect of surgical position on the development of postoperative atelectasis in patients undergoing surgery in supine, prone, lateral decubitus, and lithotomy positions using lung ultrasonography (LUS), and to investigate whether there is a difference between these positions.
Detailed description
Study Groups: Patients will be divided into 4 groups according to the surgical position to be given during the operation:
- Group 1 (Supine, n=25)
- Group 2 (Prone, n=25)
- Group 3 (Lateral Decubitus, n=25)
- Group 4 (Lithotomy, n=25) All patients will receive standard anesthesia induction and maintenance with 1 mcg/kg fentanyl citrate, 2 mg/kg propofol, 0.6 mg/kg rocuronium intravenously, followed by maintenance with desfluran at a MAC of 0.8-1.2 (if necessary). Patient demographic data (age, gender, height, weight, BMI, ASA score, comorbidities) and intraoperative data (heart rate, SpO2, mean arterial pressure, duration of surgery, surgical position, applied PEEP level) will be recorded.
Lung Ultrasonography (LUS) Protocol: LUS evaluation, Dr. The ultrasound will be performed by Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe]. LUS will be performed using a 12-zone protocol consisting of 6 standard zones (upper and lower quadrants of the anterior, lateral, and posterior regions) for both hemithoraxes. The evaluation will be performed at 3 different time points:
- Preoperative (T0): Immediately before anesthesia induction, in the supine position (Baseline).
- Postoperative (T1): Immediately before the patient is awakened, in the supine position.
- Postoperative (T2): 20 minutes after the patient is transferred to the PACU. MLUS Scoring: Each region will be scored between 0-3 according to lung ventilation (MLUS Score):
- 0 Points: Normal ventilation (presence of A-line, fewer than 3 B-lines)
- 1 Point: Minor ventilation loss (≥ 3 B-lines or subpleural consolidations ≤ 1 cm in diameter separated by a normal pleural line)
- 2 Points: Moderate ventilation loss (Multiple small subpleural consolidations ≤ 1 cm in diameter separated by multiple and converging B-lines or a thickened/irregular pleural line)
- 3 Points: Severe ventilation loss (At least one consolidation > 1 cm in diameter or subpleural consolidations > 1x2 cm in diameter) The total MLUS score will be obtained by summing the scores of the 12 regions (Minimum 0, Maximum 36). Atelectasis will be defined as "predisposition to atelectasis when each quadrant score is 2 or 3".
Study design
- Observational model
- Case only
- Time perspective
- Prospective
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Group 1 | – | Procedure: lung ultrasoundSupine position |
| group 2 | – | Procedure: lung ultrasoundprone position |
| group 3 | – | Procedure: lung ultrasoundlateral decubitus |
| Group 4 | – | Procedure: lung ultrasoundlithotomy |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- The study will include a total of 100 patients in 4 groups, aged 18-65 years, with an ASA (American Society of Anesthesiologists) physical status between I and III, who are scheduled to undergo general anesthesia in supine, prone, lateral decubitus, and lithotomy positions.
Key inclusion criteria (4 listed)
- Being between 18-80 years of age
- Having ASA I-III status
- Planning elective surgery under general anesthesia
- Agreeing to participate in the study and signing the consent form
Key exclusion criteria (13 listed)
- Patients requiring emergency surgery
- Patients with ASA IV or higher
- Presence of a known serious preoperative lung disease (COPD, Asthma, Pneumonia, Pleural effusion, Pneumothorax, Interstitial lung disease, Bronchiectasis, etc.)
- History of neuromuscular disease
- Body Mass Index (BMI) > 35 kg/m² (Morbid obesity)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| lung ultrasoundLung Ultrasound (LUS) Protocol: The LUS evaluation will be performed by Dr. Burak Ağar using a Mindray ultrasound device [Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe] | Procedure or surgery | Group 1, Group 4, group 2, group 3 |
Primary outcome
Modified Lung Ultrasound Score
Time frame: 1. (T0):Immediately before anesthesia induction, in the supine position 2.(T1): Immediately before the patient is awakened, in the supine posit 3.(T2):Twenty minutes after the patient was admitted to the PACU (Post-Anesthesia Care Unit)
MLUS Scoring: Each region will be scored between 0-3 according to lung ventilation (MLUS Score): * 0 Points: Normal ventilation (presence of A-line, fewer than 3 B-lines) * 1 Point: Minor ventilation loss (≥ 3 B-lines or subpleural consolidations ≤ 1 cm in diameter separated by a normal pleural line) * 2 Points: Moderate ventilation loss (Multiple small subpleural consolidations ≤ 1 cm in diameter separated by multiple and converging B-lines or a thickened/irregular pleural line) * 3 Points: Severe ventilation loss (At least one consolidation > 1 cm in diameter or subpleural consolidations > 1x2 cm in diameter) The total MLUS score will be obtained by summing the scores of the 12 regions (Minimum 0, Maximum 36). Atelectasis will be defined as "predisposition to atelectasis when each quadrant score is 2 or 3"
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Jul 2026.
- Individual participant dataSharing planned: No
Related trials for Lung Ultrasound
Not yet recruiting
Expanded Diagnostic Strategy in Older Adults Hospitalized With Community-Acquired Acute Respiratory Infection
Acute Respiratory Infection
Not yet recruitingObservational study
Preoperative Gastric Ultrasound and Anaesthetic Management in Patients Undergoing Coronary Artery Bypass Grafting
Preoperative Fasting, Pulmonary Aspiration During Anesthetic Induction
Not yet recruitingObservational study
Ultrasound Findings in a Pediatric Population
Respiratory Tract Infections (RTI), Lung Ultrasound
Active, not recruiting
Molecular Analysis of Endoscopic Cytology Samples Supernatant in Pulmonary Nodules
Lung Cancer, Lung; Node
Not yet recruitingObservational study
Diaphragm Ultrasound and Neuromuscular Monitoring for Predicting Early Respiratory Events After Extubation
Residual Neuromuscular Blockade, Diaphragm Dysfunction
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Lung Ultrasound and Atelectasis, run by Cumhuriyet University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 13 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 21 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Modified Lung Ultrasound Score (time frame: 1. (T0):Immediately before anesthesia induction, in the supine position 2.(T1): Immediately before the patient is awakened, in the supine posit 3.(T2):Twenty minutes after the patient was admitted to the PACU (Post-Anesthesia Care Unit)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Jul 2026.