Maternal and Fetal Outcomes in Elective vs Emergency Cesarean SectionNCT07651241
Maternal and Fetal Outcomes in Elective vs Emergency Cesarean Section
An observational study of Maternal and Fetal Outcomes in Elective vs Emergency Cesarean Section, run by Assiut University.
Trial summary
Cesarean section (CS) rates have increased substantially worldwide and in Egypt, where they now account for the majority of deliveries. Maternal and neonatal outcomes may differ between elective and emergency CS. Read more about this study
- Who is it for?
- Ages 18 to 45 years, women only
- Conditions the study is for
- Maternal and Fetal Outcomes in Elective vs Emergency Cesarean Section
- What is being tested?
- emergency cesarean section and elective cesarean section
- Type of treatment
- Surgery or procedure
- How many people
- 210 participants
- Where
- No sites listed yet
- Study dates
- 1 Jul 2026to 1 Sep 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- Women only
- No healthy volunteers
- Adult
Study population: Pregnant women undergoing cesarean section (elective or emergency) at Women's Health Hospital during the study period. Eligible participants will include women with singleton pregnancies who meet the inclusion criteria and provide complete clinical data. Maternal and neonatal outcomes will be assessed and compared between elective and emergency cesarean section groups.
Who may be able to join
- 1- Pregnant women undergoing cesarean section 2- Singleton pregnancy 3- Gestational age ≥ 28 weeks 4- Age 18-45 years
Who cannot join
- 1- Multiple pregnancy 2- Known fetal anomalies 3- Intrauterine fetal demise before cesarean section 4- Severe maternal comorbidities (e.g., cardiac disease, renal failure) 5- Rupture uterus 6- patients with placenta previa or accreta spectrum
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Maternal and Fetal Outcomes in Elective and Emergency Cesarean Section in Women's Health Hospital
Cesarean section (CS) rates have increased substantially worldwide and in Egypt, where they now account for the majority of deliveries. Maternal and neonatal outcomes may differ between elective and emergency CS. Emergency cesarean sections are generally associated with higher maternal morbidity, including increased risks of postpartum hemorrhage, infection, blood transfusion, longer operative time, and prolonged hospital stay. Neonatal outcomes following emergency CS may also be less favorable, with higher rates of low Apgar scores, respiratory distress, and NICU admission. However, findings remain inconsistent across studies, highlighting the need for further prospective research to comprehensively compare maternal and fetal outcomes between elective and emergency cesarean deliveries.
- Being tested
- emergency cesarean section, elective cesarean section
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
emergency cesarean sectionProcedure or surgery
emergency cesarean section
elective cesarean sectionProcedure or surgery
elective cesarean section
What is being measured
The primary outcome is the main question the study is designed to answer.
• Maternal morbidity composite outcome • Neonatal morbidity composite outcome
Measured: From cesarean delivery until hospital discharge (up to 7 days postpartum).
Secondary outcomes (5)
Length of stay
Measured: From cesarean delivery until maternal hospital discharge (days), up to 7 days postpartum.
Operative time
Measured: Assessed during cesarean section, from skin incision to skin closure (minutes).
Infection rate
Measured: From cesarean delivery through 6 weeks postpartum.
Effect of confounding factors on neonatal outcomes (gestational age at delivery, type of anaesthesia)
Measured: Assessed at birth and during neonatal hospitalization, up to 28 days after birth.
Effect of confounding factors on maternal outcomes (BMI)
Measured: BMI assessed at admission for delivery; association with maternal outcomes evaluated from cesarean delivery through hospital discharge (up to 7 days postpartum).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jun 2026
- Study start1 Jul 2026 (estimated)
- Primary completion1 Jul 2027 (estimated)
- Study completion1 Sep 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (8)Papers the sponsor has linked to this study.
- Other trials for Maternal and Fetal Outcomes in Elective vs Emergency Cesarean SectionStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 210 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Abdelsalam Gomaa, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07651241
- Sponsor's protocol ID
- MF_CS_2026
- Status last verified
- Jun 2026
- First submitted
- 11 Jun 2026
- Last updated
- 16 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Lucas DN, Yentis SM, Kinsella SM, Holdcroft A, May AE, Wee M, Robinson PN. Urgency of caesarean section: a new classification. J R Soc Med. 2000 Jul;93(7):346-50. doi: 10.1177/014107680009300703.
PubMed 10928020Boerma T, Ronsmans C, Melesse DY, Barros AJD, Barros FC, Juan L, Moller AB, Say L, Hosseinpoor AR, Yi M, de Lyra Rabello Neto D, Temmerman M. Global epidemiology of use of and disparities in caesarean sections. Lancet. 2018 Oct 13;392(10155):1341-1348. doi: 10.1016/S0140-6736(18)31928-7.
PubMed 30322584Khasawneh W, Obeidat N, Yusef D, Alsulaiman JW. The impact of cesarean section on neonatal outcomes at a university-based tertiary hospital in Jordan. BMC Pregnancy Childbirth. 2020 Jun 1;20(1):335. doi: 10.1186/s12884-020-03027-2.
PubMed 32487165Souza JP, Gulmezoglu A, Lumbiganon P, Laopaiboon M, Carroli G, Fawole B, Ruyan P; WHO Global Survey on Maternal and Perinatal Health Research Group. Caesarean section without medical indications is associated with an increased risk of adverse short-term maternal outcomes: the 2004-2008 WHO Global Survey on Maternal and Perinatal Health. BMC Med. 2010 Nov 10;8:71. doi: 10.1186/1741-7015-8-71.
PubMed 21067593Sandall J, Tribe RM, Avery L, Mola G, Visser GH, Homer CS, Gibbons D, Kelly NM, Kennedy HP, Kidanto H, Taylor P, Temmerman M. Short-term and long-term effects of caesarean section on the health of women and children. Lancet. 2018 Oct 13;392(10155):1349-1357. doi: 10.1016/S0140-6736(18)31930-5.
PubMed 30322585Doke PP, Vaidya VM, Narula APS, Patil AV, Panchanadikar TM, Wagh GN, Iyengar KS. Relative risk of postpartum maternal morbidity among cesarean-delivered women: A multisite prospective cohort study in a large district, India. J Family Med Prim Care. 2022 Dec;11(12):7705-7712. doi: 10.4103/jfmpc.jfmpc_1292_22. Epub 2023 Jan 17.
PubMed 36994031Abdel-Aleem H, Shaaban OM, Hassanin AI, Ibraheem AA. Analysis of cesarean delivery at Assiut University Hospital using the Ten Group Classification System. Int J Gynaecol Obstet. 2013 Nov;123(2):119-23. doi: 10.1016/j.ijgo.2013.05.011. Epub 2013 Jul 31.
PubMed 23958586Betran AP, Torloni MR, Zhang JJ, Gulmezoglu AM; WHO Working Group on Caesarean Section. WHO Statement on Caesarean Section Rates. BJOG. 2016 Apr;123(5):667-70. doi: 10.1111/1471-0528.13526. Epub 2015 Jul 22. No abstract available.
PubMed 26681211
Study at a glance
From the registry record, last updated by the sponsor on 16 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Maternal and Fetal Outcomes in Elective and Emergency Cesarean Section in Women's Health Hospital
- ClinicalTrials.gov ID
- NCT07651241
- Acronym / sponsor ID
- MF_CS_2026
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 210 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- 1 Jul 2026 (estimated)
- Primary completion
- 1 Jul 2027 (estimated)
- Study completion
- 1 Sep 2027 (estimated)
- First posted
- 16 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Cesarean section (CS) rates have increased substantially worldwide and in Egypt, where they now account for the majority of deliveries. Maternal and neonatal outcomes may differ between elective and emergency CS. Emergency cesarean sections are generally associated with higher maternal morbidity, including increased risks of postpartum hemorrhage, infection, blood transfusion, longer operative time, and prolonged hospital stay. Neonatal outcomes following emergency CS may also be less favorable, with higher rates of low Apgar scores, respiratory distress, and NICU admission. However, findings remain inconsistent across studies, highlighting the need for further prospective research to comprehensively compare maternal and fetal outcomes between elective and emergency cesarean deliveries.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 45 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult
- Study population
- Pregnant women undergoing cesarean section (elective or emergency) at Women's Health Hospital during the study period. Eligible participants will include women with singleton pregnancies who meet the inclusion criteria and provide complete clinical data. Maternal and neonatal outcomes will be assessed and compared between elective and emergency cesarean section groups.
Key inclusion criteria (1 listed)
- 1- Pregnant women undergoing cesarean section 2- Singleton pregnancy 3- Gestational age ≥ 28 weeks 4- Age 18-45 years
Key exclusion criteria (1 listed)
- 1- Multiple pregnancy 2- Known fetal anomalies 3- Intrauterine fetal demise before cesarean section 4- Severe maternal comorbidities (e.g., cardiac disease, renal failure) 5- Rupture uterus 6- patients with placenta previa or accreta spectrum
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| emergency cesarean sectionemergency cesarean section | Procedure or surgery | – |
| elective cesarean sectionelective cesarean section | Procedure or surgery | – |
Primary outcome
• Maternal morbidity composite outcome • Neonatal morbidity composite outcome
Time frame: From cesarean delivery until hospital discharge (up to 7 days postpartum).
5 secondary outcomes
Length of stay
Time frame: From cesarean delivery until maternal hospital discharge (days), up to 7 days postpartum.
Operative time
Time frame: Assessed during cesarean section, from skin incision to skin closure (minutes).
Infection rate
Time frame: From cesarean delivery through 6 weeks postpartum.
Effect of confounding factors on neonatal outcomes (gestational age at delivery, type of anaesthesia)
Time frame: Assessed at birth and during neonatal hospitalization, up to 28 days after birth.
Effect of confounding factors on maternal outcomes (BMI)
Time frame: BMI assessed at admission for delivery; association with maternal outcomes evaluated from cesarean delivery through hospital discharge (up to 7 days postpartum).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jun 2026.
- Background: PubMed 10928020Lucas DN, Yentis SM, Kinsella SM, Holdcroft A, May AE, Wee M, Robinson PN. Urgency of caesarean section: a new classification. J R Soc Med. 2000 Jul;93(7):346-50. doi: 10.1177/014107680009300703.
- Background: PubMed 30322584Boerma T, Ronsmans C, Melesse DY, Barros AJD, Barros FC, Juan L, Moller AB, Say L, Hosseinpoor AR, Yi M, de Lyra Rabello Neto D, Temmerman M. Global epidemiology of use of and disparities in caesarean sections. Lancet. 2018 Oct 13;392(10155):1341-1348. doi: 10.1016/S0140-6736(18)31928-7.
- Background: PubMed 32487165Khasawneh W, Obeidat N, Yusef D, Alsulaiman JW. The impact of cesarean section on neonatal outcomes at a university-based tertiary hospital in Jordan. BMC Pregnancy Childbirth. 2020 Jun 1;20(1):335. doi: 10.1186/s12884-020-03027-2.
- Results publication: PubMed 21067593Souza JP, Gulmezoglu A, Lumbiganon P, Laopaiboon M, Carroli G, Fawole B, Ruyan P; WHO Global Survey on Maternal and Perinatal Health Research Group. Caesarean section without medical indications is associated with an increased risk of adverse short-term maternal outcomes: the 2004-2008 WHO Global Survey on Maternal and Perinatal Health. BMC Med. 2010 Nov 10;8:71. doi: 10.1186/1741-7015-8-71.
- Results publication: PubMed 30322585Sandall J, Tribe RM, Avery L, Mola G, Visser GH, Homer CS, Gibbons D, Kelly NM, Kennedy HP, Kidanto H, Taylor P, Temmerman M. Short-term and long-term effects of caesarean section on the health of women and children. Lancet. 2018 Oct 13;392(10155):1349-1357. doi: 10.1016/S0140-6736(18)31930-5.
- Results publication: PubMed 36994031Doke PP, Vaidya VM, Narula APS, Patil AV, Panchanadikar TM, Wagh GN, Iyengar KS. Relative risk of postpartum maternal morbidity among cesarean-delivered women: A multisite prospective cohort study in a large district, India. J Family Med Prim Care. 2022 Dec;11(12):7705-7712. doi: 10.4103/jfmpc.jfmpc_1292_22. Epub 2023 Jan 17.
- Results publication: PubMed 23958586Abdel-Aleem H, Shaaban OM, Hassanin AI, Ibraheem AA. Analysis of cesarean delivery at Assiut University Hospital using the Ten Group Classification System. Int J Gynaecol Obstet. 2013 Nov;123(2):119-23. doi: 10.1016/j.ijgo.2013.05.011. Epub 2013 Jul 31.
- Results publication: PubMed 26681211Betran AP, Torloni MR, Zhang JJ, Gulmezoglu AM; WHO Working Group on Caesarean Section. WHO Statement on Caesarean Section Rates. BJOG. 2016 Apr;123(5):667-70. doi: 10.1111/1471-0528.13526. Epub 2015 Jul 22. No abstract available.
- Individual participant dataSharing planned: Undecided
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
An observational study of Maternal and Fetal Outcomes in Elective vs Emergency Cesarean Section, run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 16 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Alwany Elsenousy Eldreemy Elkasse, professor (+2001225005036, alwany.elsenousy@med.aun.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
• Maternal morbidity composite outcome • Neonatal morbidity composite outcome (time frame: From cesarean delivery until hospital discharge (up to 7 days postpartum).). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07651241, which also lists 8 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jun 2026.