Autism Spectrum DisorderNCT07644468
Visual Rehabilitation in Children With Autism Spectrum Disorder and Visual Disorders
A study testing Visual Rehabilitation in people with Autism Spectrum Disorder and Visual Rehabilitation, run by National Taiwan University Hospital at 1 site in Taiwan.
Trial summary
Children with autism spectrum disorder (ASD) often have visual problems that add difficulty to social interaction and communication. This study implemented a visual rehabilitation program to improve visual function and functional use of visual information in children with ASD and co-occurring visual difficulties. Read more about this study
- Who is it for?
- Ages 1 year to 8 years
- Conditions the study is for
- Autism Spectrum Disorder, Visual Rehabilitation, Vision
- What is being tested?
- Visual Rehabilitation
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 9 participants
- Where
- 1 siteTaiwan
- Study dates
- 18 Mar 2024to 31 Oct 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 1 year to 8 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Language developmental age between 12 and 36 months
- Diagnosis or suspected diagnosis of ASD based on DSM criteria
- Best-corrected binocular visual acuity between 0.1 and 0.5, or other marked intra-individual variability across visual perceptual tasks
- Ability to follow at least two-step commands in daily activities
Who cannot join
- Moderate to severe intellectual disability
Trial locations and contacts
1 site in 1 country.
Taiwan1 site
National Taiwan University, College of Medicine, School of Occupational Therapy
Taipei, 100
About this study
Official title: The Effects of Visual Rehabilitation on Social Interaction and Communication for Children With Autism Spectrum Disorders and Visual Disorders
Children with autism spectrum disorder (ASD) often have visual problems that add difficulty to social interaction and communication. This study implemented a visual rehabilitation program to improve visual function and functional use of visual information in children with ASD and co-occurring visual difficulties. After the program, children showed improved visual abilities, eye contact, and attention during shared activities. The study also confirmed that the Early Social Communication Scales (ESCS) is a practical and reliable tool for tracking these improvements. Overall, the results suggest that helping children with ASD improve their vision may also support their social and communication development.
- Being tested
- Visual Rehabilitation
- Keywords
- autism spectrum disorder, social communication, vision, visual function, visual rehabilitation, visual difficulty, reliability
- Medical subject headings
- Autism Spectrum Disorder, Communication, Vision Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Visual RehabilitationBehavioural
Participants received an individualized visual rehabilitation program that included PowerPoint-based visual training games and visual perceptual activities. The program was delivered in weekly one-on-one sessions of 1 hr over a 10-week period.
| Study group | Role | What they receive |
|---|---|---|
| Visual Rehabilitation | Experimental | Participants received an individualized visual rehabilitation program that included PowerPoint-based visual training games and visual perceptual activities. The program was delivered in weekly one-on-one sessions of 1 hr over a 10-week period. Receives: Behavioral: Visual Rehabilitation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Visual Function Battery for Children with Special Needs, VFB-CSN
The VFB-CSN is a standardized observable measure of visual function for children with special needs. The VFB-CSN can assess eight visual functions: Visual Reflex, Ocular Muscle Balance/ Imbalance, Visual Acuity, Oculomotor, Visual Field, Contrast Sensitivity, Color/ Form Vision, and Visual Attention. The highest possible total score is 60. The VFB-CSN has shown excellent inter-rater reliability and good ecological validity.
Measured: Measured at baseline (within 2 weeks prior to the intervention) and post-intervention (within 2 weeks after completion of the program).
Early Social Communication Scales, ESCS
The ESCS is a standardized video coding measure of social communication skills for children with a language developmental age between 8 and 30 months. The ESCS can assess three domains: Joint Attention, Behavioral Request, and Social Interaction. The ESCS has no total score or scoring ceiling; most of the behaviors are documented as counts. The ESCS demonstrates excellent to moderate inter-rater reliability and good construct validity.
Measured: Measured at baseline (within 2 weeks prior to the intervention) and post-intervention (within 2 weeks after completion of the program).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Jun 2026
- Study start18 Mar 2024
- Primary completion3 Jun 2025
- Study completion31 Oct 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Autism Spectrum DisorderStudies of the same condition, open and under way.
- More trials run by National Taiwan University HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 9 participants (actual)
Sponsor and investigators
- Lead sponsor
- National Taiwan University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07644468
- Sponsor's protocol ID
- 202311042RINB
- Status last verified
- Jan 2024
- First submitted
- 8 Jun 2026
- Last updated
- 12 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 12 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of Visual Rehabilitation on Social Interaction and Communication for Children With Autism Spectrum Disorders and Visual Disorders
- ClinicalTrials.gov ID
- NCT07644468
- Acronym / sponsor ID
- 202311042RINB
- Keywords
- autism spectrum disorder, social communication, vision, visual function, visual rehabilitation, visual difficulty, reliability
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 9 participants (actual)
- Lead sponsor
- National Taiwan University HospitalUniversity, hospital or other
- Study start
- 18 Mar 2024 (actual)
- Primary completion
- 3 Jun 2025 (actual)
- Study completion
- 31 Oct 2025 (actual)
- First posted
- 12 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Children with autism spectrum disorder (ASD) often have visual problems that add difficulty to social interaction and communication. This study implemented a visual rehabilitation program to improve visual function and functional use of visual information in children with ASD and co-occurring visual difficulties. After the program, children showed improved visual abilities, eye contact, and attention during shared activities. The study also confirmed that the Early Social Communication Scales (ESCS) is a practical and reliable tool for tracking these improvements. Overall, the results suggest that helping children with ASD improve their vision may also support their social and communication development.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Visual Rehabilitation | Experimental | Behavioral: Visual RehabilitationParticipants received an individualized visual rehabilitation program that included PowerPoint-based visual training games and visual perceptual activities. The program was delivered in weekly one-on-one sessions of 1 hr over a 10-week period. |
Who may qualify
- Ages
- 1 year to 8 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (4 listed)
- Language developmental age between 12 and 36 months
- Diagnosis or suspected diagnosis of ASD based on DSM criteria
- Best-corrected binocular visual acuity between 0.1 and 0.5, or other marked intra-individual variability across visual perceptual tasks
- Ability to follow at least two-step commands in daily activities
Key exclusion criteria (1 listed)
- Moderate to severe intellectual disability
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Visual RehabilitationParticipants received an individualized visual rehabilitation program that included PowerPoint-based visual training games and visual perceptual activities. The program was delivered in weekly one-on-one sessions of 1 hr over a 10-week period. | Behavioural | Visual Rehabilitation |
Primary outcome
Visual Function Battery for Children with Special Needs, VFB-CSN
Time frame: Measured at baseline (within 2 weeks prior to the intervention) and post-intervention (within 2 weeks after completion of the program).
The VFB-CSN is a standardized observable measure of visual function for children with special needs. The VFB-CSN can assess eight visual functions: Visual Reflex, Ocular Muscle Balance/ Imbalance, Visual Acuity, Oculomotor, Visual Field, Contrast Sensitivity, Color/ Form Vision, and Visual Attention. The highest possible total score is 60. The VFB-CSN has shown excellent inter-rater reliability and good ecological validity.
Early Social Communication Scales, ESCS
Time frame: Measured at baseline (within 2 weeks prior to the intervention) and post-intervention (within 2 weeks after completion of the program).
The ESCS is a standardized video coding measure of social communication skills for children with a language developmental age between 8 and 30 months. The ESCS can assess three domains: Joint Attention, Behavioral Request, and Social Interaction. The ESCS has no total score or scoring ceiling; most of the behaviors are documented as counts. The ESCS demonstrates excellent to moderate inter-rater reliability and good construct validity.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Jun 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Visual Rehabilitation in people with Autism Spectrum Disorder and Visual Rehabilitation, run by National Taiwan University Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 12 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Visual Function Battery for Children with Special Needs, VFB-CSN (time frame: Measured at baseline (within 2 weeks prior to the intervention) and post-intervention (within 2 weeks after completion of the program).). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Jun 2026.