Wrist Joint HypermobilityNCT07639918

Effect of Kinesio-taping With Routine Physical Therapy in Wrist Joint Hypermobility

A study testing Routine Physical Therapy Protocol for Wrist Joint and Kinesio Taping (Y-strip Technique) in people with Wrist Joint Hypermobility, run by University of Lahore at 1 site in Pakistan.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

Search all trials

Trial summary

Who is it for?: Ages 18 to 40 years
Conditions the study is for: Wrist Joint Hypermobility
What is being tested?: Routine Physical Therapy Protocol for Wrist Joint and Kinesio Taping (Y-strip Technique)
Type of treatment: Medical device
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 38 participants
Where: 1 sitePakistan
Study dates: 30 Sep 2025to 15 Jun 2026
Phase: Interventional
Are there results?: None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 to 40 years
All sexes
No healthy volunteers
Adult

Who may be able to join

Male and female participants
Aged 18 to 40 years.
Beighton score greater than or equal to 4 either less than 4 with positive family history of hypermobility
Intermittent or persistent wrist pain in one or both hands for more than 3 years.
Passive range of motion less than 50 degree in wrist extension

Who cannot join

Surgical history on wrist joint and upper limb in past 12 months.
Inflammatory and infectious joint diseases like rheumatoid arthritis, wrist OA.
Acute trauma or neurological conditions including radiculopathy, plexopathy, tunnel syndromes.
Current or past use of splints or pain-related medications.
Medication influencing joint mobility including corticosteroids, HRT, lipid-lowering drugs.
Pregnant women and those less than 1 year postpartum

Trial locations and contacts

1 site in 1 country.

Pakistan1 site

University of Lahore Teaching Hospital
Lahore, Punjab Province, 55150

Other trials in Pakistan

About this study

Official title: Routine Physical Therapy With and Without Kinesio Taping Among Patients With Wrist Joint Hypermobility

The study will be randomized controlled trial. This study will be conducted at the University of Lahore Teaching Hospital, Lahore, Pakistan. This will investigate the effects of routine physical therapy with and without Kinesio taping in patients with Wrist Joint Hypermobility. A sample size of 38 participants will be randomly assigned into two groups. Group A will receive routine physical therapy protocol, while Group B will receive the same protocol with additional Kinesio taping. The interventions will be delivered three times per week for 8 weeks. Clinical outcomes, including pain, range of motion, and functionality, will be assessed at baseline and after 8 weeks using standardized tools.

Read the detailed description

Screening: All participants will be screened according to inclusion and exclusion criteria. Eligible individuals will provide written informed consent prior to participation.

Randomization \& Allocation: Participants will be randomized into two groups using the lottery method.

Blinding: This will be a single-blind study in which the assessor will be blinded to group allocation.

Group A (Control): Participants will receive routine physical therapy treatment including Transcutaneous Electrical Nerve Stimulation (TENS), cryotherapy (if swelling), splinting recommendations, passive or active Range of Motion (ROM), strengthening, proprioceptive, dynamic and functional training exercises. Sessions will last 45 minutes, 3 times per week for 8 weeks.

Group B (Experimental): Participants will receive the same routine physical therapy protocol, plus Kinesio taping (Y-strip method) applied to the wrist joint. Each session will last 45 minutes, 3 times per week for 8 weeks.

Outcome Variables:

Pain will be measured with the Numeric Pain Rating Scale (NPRS).
Wrist Functionality with the Patient-Rated Wrist Evaluation (PRWE)
Wrist range of motion with a universal Goniometer. Assessments will be done at baseline and after 8 weeks.

Conditions: Wrist Joint Hypermobility
Being tested: Routine Physical Therapy Protocol for Wrist Joint, Kinesio Taping (Y-strip Technique)
Keywords: Wrist Instability, Kinesio Taping, Wrist Pain, Joint Hypermobility
Medical subject headings: Joint Instability

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Routine Physical Therapy Protocol for Wrist JointOther
Also called Intervention for Arm 1
The routine physical therapy protocol includes:
Transcutaneous Electrical Nerve Stimulation (TENS): 10 minutes (80 Hz, pulse width 50-100 µs); avoided if swelling is present.
Cryotherapy: Used when swelling is present. Splinting: Static splints recommended for rest or night; dynamic splints for activity (as needed).
Passive \& Active Range of Motion (ROM) Exercises: Flexion, extension, radial and ulnar deviation (3 sets of 7 repetitions).
Manual Resistance Strengthening: Flexion, extension, radial and ulnar deviation (3 sets of 10 repetitions).
Wrist Curls and Reverse Wrist Curls: 0.5-1 kg weight (3 sets of 7 repetitions). Proprioceptive Training: Wrist circles, tendon gliding (3 sets of 10 repetitions).
Dynamic Strengthening: Resistance band flexion and extension (3 sets of 12 repetitions).
Grip Strengthening: Soft ball/Thera putty (3 sets of 10 reps) Functional Training: Task-specific activities for 5 minutes. Frequency: 3 sessions per week for 8 weeks. Session Duration: 45 minutes
Kinesio Taping (Y-strip Technique)Device
Kinesio taping will be applied in "Y" configuration using 5-cm elastic therapeutic tape.
Procedure:
1. Tape Preparation: One base strip 10 cm Two tails 7-10 cm each
2. Application: Base Anchor: Placed over the carpal region above the wrist crease. Radial Tail: Applied along forearm/wrist flexors toward the thumb side. Ulnar Tail: Applied along extensor surface toward the little-finger side.
3. Aftercare:
Patient checks wrist movement for comfort. Tape should remain dry for one hour post-application.
Session details (combined):
45-minute sessions Heat pack or TENS for 10 minutes (if no swelling) ROM, strengthening, proprioception, dynamic training Tape applied in final 10 minutes Frequency: 3 sessions/week for 8 weeks A complete home-exercise program is also provided.

Study groups in NCT07639918
Study group	Role	What they receive
A - Control (Routine Physical Therapy)	Active comparator	Participants in this arm will receive the routine physical therapy protocol for wrist joint hypermobility. Treatment includes pain-modality management (Transcutaneous Electrical Nerve Stimulation (TENS) or cryotherapy depending on swelling), wrist joint passive and active range of motion exercises, strengthening exercises, proprioceptive training, dynamic strengthening, grip training, and task-specific functional exercises. A structured home-exercise plan is also provided. Receives: Other: Routine Physical Therapy Protocol for Wrist Joint
B - Experimental (Routine Physical Therapy with Kinesio Taping)	Experimental	Participants in this arm will receive the same routine physical therapy protocol as Arm 1, with the addition of Kinesio taping applied to the wrist using a standardized "Y-strip" method. Kinesio tape is applied in the final 10 minutes of each session. Receives: Device: Kinesio Taping (Y-strip Technique)

What is being measured

The primary outcome is the main question the study is designed to answer.

Numeric Pain Rating Scale (NPRS)
The Numeric Pain Rating Scale (NPRS) is an 11 point scale used to assess wrist pain intensity, ranging from 0 to 10, where 0 indicates no pain and 10 indicates worst imaginable pain. Higher scores indicate greater pain intensity.
Measured: Baseline and at the end of 8 weeks
Patient Rated Wrist Evaluation (PRWE)
The Patient Rated Wrist Evaluation (PRWE) questionnaire is a self reported questionnaire used to assess wrist pain and functional disability. The total score ranges from 0 to 100, with higher scores indicating greater pain and disability.
Measured: Baseline and at the end of 8 weeks
Wrist Range of Motion
Wrist range of motion will be measured using a universal goniometer in degrees for wrist flexion, extension, radial deviation, and ulnar deviation. Higher values indicate greater wrist mobility.
Measured: Baseline and at the end of 8 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

30 Sep 202515 Jun 2026

First posted10 Jun 2026
Study start30 Sep 2025
Primary completion15 May 2026
Study completion15 Jun 2026

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Publications (10)Papers the sponsor has linked to this study.
Other trials for Wrist Joint HypermobilityStudies of the same condition, open and under way.
More trials run by University of LahoreThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Single blind
Who is masked: Outcomes assessor
Enrolment: 38 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07639918
Sponsor's protocol ID: UOL/IREB/25/09/0055
Status last verified: Aug 2025
First submitted: 13 May 2026
Last updated: 8 Jul 2026
Results posted: No
Data monitoring committee: Yes
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Publications

Farhadian M, Morovati Z, Shamsoddini A. Effect of Kinesio Taping on Pain, Range of Motion, Hand Strength, and Functional Abilities in Patients with Hand Osteoarthritis: A Pilot Randomized Clinical Trial. Arch Bone Jt Surg. 2019 Nov;7(6):551-560.
PubMed 31970261
Daman M, Shiravani F, Hemmati L, Taghizadeh S. The effect of combined exercise therapy on knee proprioception, pain intensity and quality of life in patients with hypermobility syndrome: A randomized clinical trial. J Bodyw Mov Ther. 2019 Jan;23(1):202-205. doi: 10.1016/j.jbmt.2017.12.012. Epub 2017 Dec 15.
PubMed 30691753
Kim GS, Weon JH, Kim MH, Koh EK, Jung DY. Effect of weight-bearing wrist movement with carpal-stabilizing taping on pain and range of motion in subjects with dorsal wrist pain: A randomized controlled trial. J Hand Ther. 2020 Jan-Mar;33(1):25-33. doi: 10.1016/j.jht.2019.02.001. Epub 2019 Mar 11.
PubMed 30871958
Luder G, Aeberli D, Mebes CM, Haupt-Bertschy B, Baeyens JP, Verra ML. Effect of resistance training on muscle properties and function in women with generalized joint hypermobility: a single-blind pragmatic randomized controlled trial. BMC Sports Sci Med Rehabil. 2021 Feb 8;13(1):10. doi: 10.1186/s13102-021-00238-8.
PubMed 33557909
Jung KS, Jung JH, Shin HS, Park JY, In TS, Cho HY. The Effects of Taping Combined with Wrist Stabilization Exercise on Pain, Disability, and Quality of Life in Postpartum Women with Wrist Pain: A Randomized Controlled Pilot Study. Int J Environ Res Public Health. 2021 Mar 30;18(7):3564. doi: 10.3390/ijerph18073564.
PubMed 33808137
Chaiparinya P, Gaogasigam C. Prevalence, frontal plane knee alignment, and lower limb joint pain and injury in generalized joint hypermobility in Thai physical therapy students. Reumatologia. 2022;60(2):116-124. doi: 10.5114/reum.2022.115621. Epub 2022 May 18.
PubMed 35782028
Chanthana P, Atthakomol P, Manosroi W, Wongpakaran T, Kraisarin J, Sananpanich K. Comparison of patient preferences and responsiveness among common patient-reported outcome measures for hand/wrist injuries or disorders. J Orthop Traumatol. 2023 Jan 9;24(1):2. doi: 10.1186/s10195-022-00681-4.
PubMed 36622514
Ituen OA, Anieto EM, Ferguson G, Duysens J, Smits-Engelsman B. Prevalence and Demographic Distribution of Hypermobility in a Random Group of School-Aged Children in Nigeria. Healthcare (Basel). 2023 Apr 11;11(8):1092. doi: 10.3390/healthcare11081092.
PubMed 37107926
Oruk DO, Karakaya MG, Yenisehir S, Karakaya IC. Effect of Kinesio taping on wrist kinematics and functional performance: A randomized controlled trial. J Hand Ther. 2023 Jan-Mar;36(1):3-12. doi: 10.1016/j.jht.2021.09.005. Epub 2021 Oct 27.
PubMed 34756489
Campos-Villegas C, Perez-Alenda S, Carrasco JJ, Igual-Camacho C, Tomas-Miguel JM, Cortes-Amador S. Effectiveness of proprioceptive neuromuscular facilitation therapy and strength training among post-menopausal women with thumb carpometacarpal osteoarthritis. A randomized trial. J Hand Ther. 2024 Apr-Jun;37(2):172-183. doi: 10.1016/j.jht.2022.07.005. Epub 2022 Aug 7.
PubMed 35948454

Study at a glance

From the registry record, last updated by the sponsor on 8 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Routine Physical Therapy With and Without Kinesio Taping Among Patients With Wrist Joint Hypermobility
ClinicalTrials.gov ID: NCT07639918
Acronym / sponsor ID: UOL/IREB/25/09/0055
Conditions: Wrist Joint Hypermobility
Keywords: Wrist Instability, Kinesio Taping, Wrist Pain, Joint Hypermobility
Study type: Interventional
Recruitment status: Completed
Enrolment: 38 participants (actual)
Lead sponsor: University of LahoreUniversity, hospital or other
Study start: 30 Sep 2025 (actual)
Primary completion: 15 May 2026 (actual)
Study completion: 15 Jun 2026 (actual)
First posted: 10 Jun 2026 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Detailed description

Screening: All participants will be screened according to inclusion and exclusion criteria. Eligible individuals will provide written informed consent prior to participation.

Randomization \& Allocation: Participants will be randomized into two groups using the lottery method.

Blinding: This will be a single-blind study in which the assessor will be blinded to group allocation.

Outcome Variables:

Pain will be measured with the Numeric Pain Rating Scale (NPRS).
Wrist Functionality with the Patient-Rated Wrist Evaluation (PRWE)
Wrist range of motion with a universal Goniometer. Assessments will be done at baseline and after 8 weeks.

Study design

Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Single blind (outcomes assessor)
Number of arms: 2

Arm	Type	Receives
A - Control (Routine Physical Therapy)	Active comparator	Other: Routine Physical Therapy Protocol for Wrist JointParticipants in this arm will receive the routine physical therapy protocol for wrist joint hypermobility. Treatment includes pain-modality management (Transcutaneous Electrical Nerve Stimulation (TENS) or cryotherapy depending on swelling), wrist joint passive and active range of motion exercises, strengthening exercises, proprioceptive training, dynamic strengthening, grip training, and task-specific functional exercises. A structured home-exercise plan is also provided.
B - Experimental (Routine Physical Therapy with Kinesio Taping)	Experimental	Device: Kinesio Taping (Y-strip Technique)Participants in this arm will receive the same routine physical therapy protocol as Arm 1, with the addition of Kinesio taping applied to the wrist using a standardized "Y-strip" method. Kinesio tape is applied in the final 10 minutes of each session.

Who may qualify

Ages: 18 to 40 years
Sex: All
Healthy volunteers: Not accepted
Age groups: Adult

Key inclusion criteria (5 listed)

Male and female participants
Aged 18 to 40 years.
Beighton score greater than or equal to 4 either less than 4 with positive family history of hypermobility
Intermittent or persistent wrist pain in one or both hands for more than 3 years.
Passive range of motion less than 50 degree in wrist extension

Key exclusion criteria (6 listed)

Surgical history on wrist joint and upper limb in past 12 months.
Inflammatory and infectious joint diseases like rheumatoid arthritis, wrist OA.
Acute trauma or neurological conditions including radiculopathy, plexopathy, tunnel syndromes.
Current or past use of splints or pain-related medications.
Medication influencing joint mobility including corticosteroids, HRT, lipid-lowering drugs.

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Routine Physical Therapy Protocol for Wrist JointAlso: Intervention for Arm 1The routine physical therapy protocol includes: Transcutaneous Electrical Nerve Stimulation (TENS): 10 minutes (80 Hz, pulse width 50-100 µs); avoided if swelling is present. Cryotherapy: Used when swelling is present. Splinting: Static splints recommended for rest or night; dynamic splints for activity (as needed). Passive \& Active Range of Motion (ROM) Exercises: Flexion, extension, radial and ulnar deviation (3 sets of 7 repetitions). Manual Resistance Strengthening: Flexion, extension, radial and ulnar deviation (3 sets of 10 repetitions). Wrist Curls and Reverse Wrist Curls: 0.5-1 kg weight (3 sets of 7 repetitions). Proprioceptive Training: Wrist circles, tendon gliding (3 sets of 10 repetitions). Dynamic Strengthening: Resistance band flexion and extension (3 sets of 12 repetitions). Grip Strengthening: Soft ball/Thera putty (3 sets of 10 reps) Functional Training: Task-specific activities for 5 minutes. Frequency: 3 sessions per week for 8 weeks. Session Duration: 45 minutes	Other	A - Control (Routine Physical Therapy)
Kinesio Taping (Y-strip Technique)Kinesio taping will be applied in "Y" configuration using 5-cm elastic therapeutic tape. Procedure: 1. Tape Preparation: One base strip 10 cm Two tails 7-10 cm each 2. Application: Base Anchor: Placed over the carpal region above the wrist crease. Radial Tail: Applied along forearm/wrist flexors toward the thumb side. Ulnar Tail: Applied along extensor surface toward the little-finger side. 3. Aftercare: Patient checks wrist movement for comfort. Tape should remain dry for one hour post-application. Session details (combined): 45-minute sessions Heat pack or TENS for 10 minutes (if no swelling) ROM, strengthening, proprioception, dynamic training Tape applied in final 10 minutes Frequency: 3 sessions/week for 8 weeks A complete home-exercise program is also provided.	Device	B - Experimental (Routine Physical Therapy with Kinesio Taping)

Primary outcome

Numeric Pain Rating Scale (NPRS)
Time frame: Baseline and at the end of 8 weeks
The Numeric Pain Rating Scale (NPRS) is an 11 point scale used to assess wrist pain intensity, ranging from 0 to 10, where 0 indicates no pain and 10 indicates worst imaginable pain. Higher scores indicate greater pain intensity.
Patient Rated Wrist Evaluation (PRWE)
Time frame: Baseline and at the end of 8 weeks
The Patient Rated Wrist Evaluation (PRWE) questionnaire is a self reported questionnaire used to assess wrist pain and functional disability. The total score ranges from 0 to 100, with higher scores indicating greater pain and disability.
Wrist Range of Motion
Time frame: Baseline and at the end of 8 weeks
Wrist range of motion will be measured using a universal goniometer in degrees for wrist flexion, extension, radial deviation, and ulnar deviation. Higher values indicate greater wrist mobility.

Results and safety

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 8 Jul 2026.
Background: PubMed 31970261Farhadian M, Morovati Z, Shamsoddini A. Effect of Kinesio Taping on Pain, Range of Motion, Hand Strength, and Functional Abilities in Patients with Hand Osteoarthritis: A Pilot Randomized Clinical Trial. Arch Bone Jt Surg. 2019 Nov;7(6):551-560.
Background: PubMed 30691753Daman M, Shiravani F, Hemmati L, Taghizadeh S. The effect of combined exercise therapy on knee proprioception, pain intensity and quality of life in patients with hypermobility syndrome: A randomized clinical trial. J Bodyw Mov Ther. 2019 Jan;23(1):202-205. doi: 10.1016/j.jbmt.2017.12.012. Epub 2017 Dec 15.
Background: PubMed 30871958Kim GS, Weon JH, Kim MH, Koh EK, Jung DY. Effect of weight-bearing wrist movement with carpal-stabilizing taping on pain and range of motion in subjects with dorsal wrist pain: A randomized controlled trial. J Hand Ther. 2020 Jan-Mar;33(1):25-33. doi: 10.1016/j.jht.2019.02.001. Epub 2019 Mar 11.
Background: PubMed 33557909Luder G, Aeberli D, Mebes CM, Haupt-Bertschy B, Baeyens JP, Verra ML. Effect of resistance training on muscle properties and function in women with generalized joint hypermobility: a single-blind pragmatic randomized controlled trial. BMC Sports Sci Med Rehabil. 2021 Feb 8;13(1):10. doi: 10.1186/s13102-021-00238-8.
Background: PubMed 33808137Jung KS, Jung JH, Shin HS, Park JY, In TS, Cho HY. The Effects of Taping Combined with Wrist Stabilization Exercise on Pain, Disability, and Quality of Life in Postpartum Women with Wrist Pain: A Randomized Controlled Pilot Study. Int J Environ Res Public Health. 2021 Mar 30;18(7):3564. doi: 10.3390/ijerph18073564.
Background: PubMed 35782028Chaiparinya P, Gaogasigam C. Prevalence, frontal plane knee alignment, and lower limb joint pain and injury in generalized joint hypermobility in Thai physical therapy students. Reumatologia. 2022;60(2):116-124. doi: 10.5114/reum.2022.115621. Epub 2022 May 18.
Background: PubMed 36622514Chanthana P, Atthakomol P, Manosroi W, Wongpakaran T, Kraisarin J, Sananpanich K. Comparison of patient preferences and responsiveness among common patient-reported outcome measures for hand/wrist injuries or disorders. J Orthop Traumatol. 2023 Jan 9;24(1):2. doi: 10.1186/s10195-022-00681-4.
Background: PubMed 37107926Ituen OA, Anieto EM, Ferguson G, Duysens J, Smits-Engelsman B. Prevalence and Demographic Distribution of Hypermobility in a Random Group of School-Aged Children in Nigeria. Healthcare (Basel). 2023 Apr 11;11(8):1092. doi: 10.3390/healthcare11081092.
Background: PubMed 34756489Oruk DO, Karakaya MG, Yenisehir S, Karakaya IC. Effect of Kinesio taping on wrist kinematics and functional performance: A randomized controlled trial. J Hand Ther. 2023 Jan-Mar;36(1):3-12. doi: 10.1016/j.jht.2021.09.005. Epub 2021 Oct 27.
Background: PubMed 35948454Campos-Villegas C, Perez-Alenda S, Carrasco JJ, Igual-Camacho C, Tomas-Miguel JM, Cortes-Amador S. Effectiveness of proprioceptive neuromuscular facilitation therapy and strength training among post-menopausal women with thumb carpometacarpal osteoarthritis. A randomized trial. J Hand Ther. 2024 Apr-Jun;37(2):172-183. doi: 10.1016/j.jht.2022.07.005. Epub 2022 Aug 7.
Individual participant dataSharing planned: No

Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Hafiza Saliha Javed, MS-MSK principal investigator

University of Lahore

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing Routine Physical Therapy Protocol for Wrist Joint and Kinesio Taping (Y-strip Technique) in people with Wrist Joint Hypermobility, run by University of Lahore at 1 site in Pakistan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 8 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Numeric Pain Rating Scale (NPRS) (time frame: Baseline and at the end of 8 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07639918, which also lists 10 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jul 2026.