Lateral Patellar Compression SyndromeTGLPRNCT07637344
Tactile Guided Lateral Patellar Release
A study testing Percutaneous lateral retinacular release of the patella in people with Lateral Patellar Compression Syndrome and Patellar Dislocation, run by Issa, Abdulhamid Sayed, M.D..
Trial summary
The lateral edge of the patella is identified by the surgeon's finger and the lateral ligament incision is performed with a blade through the skin. Read more about this study
- Who is it for?
- Ages 16 to 65 years
- Conditions the study is for
- Lateral Patellar Compression Syndrome, Patellar Dislocation, Patellar (or Kneecap) Instability and Mal-alignment
- What is being tested?
- Percutaneous lateral retinacular release of the patella
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 23 participants
- Where
- No sites listed yet
- Study dates
- 1 Jul 2014to 31 Mar 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 16 to 65 years
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Who may be able to join
- Retropatellar Pain
- Lateral Patellar Pain
Who cannot join
- Knee Arthritis grade 4
- Totally Knee Arthritis
About this study
The lateral edge of the patella is identified by the surgeon's finger and the lateral ligament incision is performed with a blade through the skin.
Read the detailed description
Under short-acting general anesthesia, the patient lies supine. The surgeon palpates to identify the lateral border of the patella; typically, the surgeon's left thumb is placed at the midpoint of this lateral edge. Using a No. 11 scalpel blade, an incision is made parallel to the lateral border of the patella-approximately 5 mm away-extending through the skin, subcutaneous layers, and lateral retinaculum, and penetrating the knee's synovial membrane to enter the joint space. This creates a small "keyhole" opening suitable for knee arthroscopy, with the sharp edge of the blade initially oriented toward the patient's head.
The tip of the blade is then angled inward into the joint to incise the lateral retinaculum superiorly, without enlarging the initial skin puncture.
The blade is then rotated 180 degrees so that its sharp edge faces toward the patient's feet. The inferior portion is incised by angling the blade inward through the subcutaneous layers, lateral retinaculum, and synovial membrane into the joint, while maintaining the original shape and size of the skin puncture without enlargement.
A sterile dressing and a compression bandage are then applied, and the patient is encouraged to begin early mobilization.
- Comparison of Clinical Success Rates Surgical Goal Isolated Release Release + Realignment Stability Success ~77.3% ~93.6% Recurrence Rate Higher (odds ~0.29) Lower (odds ~0.06)
- Conditions
- Lateral Patellar Compression Syndrome, Patellar Dislocation, Patellar (or Kneecap) Instability and Mal-alignment, Patella Alta, Patella Chondromalacia, Patella Dislocation Recurrent
- Being tested
- Percutaneous lateral retinacular release of the patella
- Keywords
- Tactile Guided Lateral Patellar Release, TGLPR, Pie Crust, Capsule-Uncut Immaculate, CUI, Lateral Retinacular Lengthening, Z-Plasty, Open Lateral Release, Isolated LPR, LPR, Lateral Patellar Compression Syndrome, LPCS, lateral retinacular release
- Medical subject headings
- Patellar Dislocation, Patella Fracture, Chondromalacia Patellae
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Percutaneous lateral retinacular release of the patellaProcedure or surgery
The lateral edge of the patella is identified by the surgeon's finger and the lateral ligament incision is performed with a blade through the skin.
| Study group | Role | What they receive |
|---|---|---|
| Tactile Guided Lateral Patellar Release | Experimental | Percutaneous lateral retinacular release of the patella Receives: Procedure: Percutaneous lateral retinacular release of the patella |
What is being measured
The primary outcome is the main question the study is designed to answer.
Less open surgery trauma
Directly going to the goal lesion with less expansion
Measured: [Time Frame: 3 minutes to 5 minutes,]
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Jun 2026
- Study start1 Jul 2014
- Primary completion30 Nov 2025
- Study completion31 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Lateral Patellar Compression SyndromeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 23 participants (actual)
Sponsor and investigators
- Lead sponsor
- Issa, Abdulhamid Sayed, M.D.
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07637344
- Sponsor's protocol ID
- TGLPR
- Acronym
- TGLPR
- Status last verified
- Jun 2026
- First submitted
- 28 May 2026
- Last updated
- 9 Jun 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 9 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Tactile Guided Lateral Patellar Release
- ClinicalTrials.gov ID
- NCT07637344
- Acronym / sponsor ID
- TGLPR / TGLPR
- Conditions
- Lateral Patellar Compression Syndrome, Patellar Dislocation, Patellar (or Kneecap) Instability and Mal-alignment, Patella Alta, Patella Chondromalacia, Patella Dislocation Recurrent
- Keywords
- Tactile Guided Lateral Patellar Release, TGLPR, Pie Crust, Capsule-Uncut Immaculate, CUI, Lateral Retinacular Lengthening, Z-Plasty, Open Lateral Release
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 23 participants (actual)
- Lead sponsor
- Issa, Abdulhamid Sayed, M.D.
- Study start
- 1 Jul 2014 (actual)
- Primary completion
- 30 Nov 2025 (actual)
- Study completion
- 31 Mar 2026 (actual)
- First posted
- 9 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The lateral edge of the patella is identified by the surgeon's finger and the lateral ligament incision is performed with a blade through the skin.
Detailed description
Under short-acting general anesthesia, the patient lies supine. The surgeon palpates to identify the lateral border of the patella; typically, the surgeon's left thumb is placed at the midpoint of this lateral edge. Using a No. 11 scalpel blade, an incision is made parallel to the lateral border of the patella-approximately 5 mm away-extending through the skin, subcutaneous layers, and lateral retinaculum, and penetrating the knee's synovial membrane to enter the joint space. This creates a small "keyhole" opening suitable for knee arthroscopy, with the sharp edge of the blade initially oriented toward the patient's head.
The tip of the blade is then angled inward into the joint to incise the lateral retinaculum superiorly, without enlarging the initial skin puncture.
The blade is then rotated 180 degrees so that its sharp edge faces toward the patient's feet. The inferior portion is incised by angling the blade inward through the subcutaneous layers, lateral retinaculum, and synovial membrane into the joint, while maintaining the original shape and size of the skin puncture without enlargement.
A sterile dressing and a compression bandage are then applied, and the patient is encouraged to begin early mobilization.
- Comparison of Clinical Success Rates Surgical Goal Isolated Release Release + Realignment Stability Success ~77.3% ~93.6% Recurrence Rate Higher (odds ~0.29) Lower (odds ~0.06)
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Tactile Guided Lateral Patellar Release | Experimental | Procedure: Percutaneous lateral retinacular release of the patellaPercutaneous lateral retinacular release of the patella |
Who may qualify
- Ages
- 16 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (2 listed)
- Retropatellar Pain
- Lateral Patellar Pain
Key exclusion criteria (2 listed)
- Knee Arthritis grade 4
- Totally Knee Arthritis
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Percutaneous lateral retinacular release of the patellaThe lateral edge of the patella is identified by the surgeon's finger and the lateral ligament incision is performed with a blade through the skin. | Procedure or surgery | Tactile Guided Lateral Patellar Release |
Primary outcome
Less open surgery trauma
Time frame: [Time Frame: 3 minutes to 5 minutes,]
Directly going to the goal lesion with less expansion
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Jun 2026.
Related trials for Lateral Patellar Compression Syndrome
Enrolling by invitation
To Compare the Clinical Efficacy of Arthroscopic Lateral Retinacular Release and Exercise Therapy in the Treatment of Lateral Patellar Crush Syndrome
Lateral Patellar Syndrome
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing Percutaneous lateral retinacular release of the patella in people with Lateral Patellar Compression Syndrome and Patellar Dislocation, run by Issa, Abdulhamid Sayed, M.D..
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 9 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Less open surgery trauma (time frame: [Time Frame: 3 minutes to 5 minutes,]). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Jun 2026.