CancerNCT07632482
Effect of Dance-based Multimodal Exercise for Managing CIPN in Cancer Patients
A study testing dance-based multimodal exercise and Exercise education in people with Cancer, run by Chinese University of Hong Kong.
Trial summary
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a significant and distressing symptom experienced by cancer patients with different cancer types. Systematic reviews demonstrate that exercise is an effective non-pharmacological strategy for managing chemotherapy-induced peripheral neuropathy (CIPN) in… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Cancer
- What is being tested?
- dance-based multimodal exercise and Exercise education
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 76 participants
- Where
- No sites listed yet
- Study dates
- 1 Jun 2026to 31 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients was diagnosed with malignant solid tumor (s) which is defined as abnormal, cancerous masses of tissue, for example, all carcinomas (such as breast cancer, stomach cancer, colorectal cancer and gynecological cancer, lung cancer and so on), sarcomas and lymphomas
- Patients experience CIPN symptoms
- Patients are able to use smart phone and WhatsApp
- Patients are able to read or understand Chinese.
Who cannot join
- Cancer patients suffer from severe organ failure or diseases that limit their level of activity
- Patients are diagnosed with non-chemotherapy induced peripheral neuropathy, such as sciatica and diabetic neuropathy
- Patients receive treatments that affect the severity of neuropathy, such as steroid, anticonvulsants and antidepressants
- Patients age below 18 years old
- Patients have cognitive impairments.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Effects of Dance-based Multimodal Exercise Programme for Managing Chemotherapy-induced Peripheral Neuropathy in Patients With Solid Tumors: A Pilot Randomized Controlled Study
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a significant and distressing symptom experienced by cancer patients with different cancer types. Systematic reviews demonstrate that exercise is an effective non-pharmacological strategy for managing chemotherapy-induced peripheral neuropathy (CIPN) in cancer patients. Multimodal exercise was found to be superior to a single-modality exercise programme. However, the lack of using Information-Motivation-Behavioral Skill (IMB) model and addressing the social motivation component in current multimodal exercise programmes for cancer patients with solid tumors.
Objectives: This study aims to evaluate the effects of a 6-week dance-based multimodal exercise program on CIPN symptoms over a 3-month period, comparing outcomes with usual care in cancer patients with solid tumors.
Read more
Methods: An assessor-blinded pilot randomized controlled trial with process evaluation will be conducted at Community Cancer Centers/ Community Centers and Non-governmental organizations. A total of 76 participants will be recruited, with both intervention and control groups receiving educational booklets and logbooks. The intervention group will engage in a 6-week dance-based multimodal exercise program, supplemented by goal-setting evaluations and motivational messaging. The control group will receive weekly exercise videos and motivational messages. Outcomes, including CIPN severity, quality of life, pain, balance, exercise knowledge, motivation, self-efficacy, and adverse effects, will be measured using validated tools at baseline, immediately post-intervention, 4 weeks post-intervention, and 12 weeks post-intervention. Process evaluation will explore perceived benefits, program awareness, and facilitators and barriers to adherence.
Conclusion: This study aims to provide an evidence-based approach for managing CIPN in cancer patients through a dance-based multimodal exercise program. It underscores the importance of incorporating the IMB model to enhance exercise adherence and support self-management of CIPN in cancer survivors.
- Conditions
- Cancer
- Being tested
- dance-based multimodal exercise, Exercise education
- Keywords
- cancers, malignant solid tumors, chemotehrapy-induced peripheral neuropathy, CIPN
- Medical subject headings
- Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
dance-based multimodal exerciseBehavioural
This study applies the Information-Motivation-Behavioral Skills (IMB) model in a six-week Zumba Gold dance program for cancer survivors. Each weekly 75-minute session includes vital sign checks, 50 minutes of multimodal exercise (warm-up, workout, cool-down), and group sharing. Dance styles taught are Merengue, Salsa, Cumbia, Belly dance, Flamenco, Tango, and cool-down, with revision in later sessions. Videos with safety guidance are shared via WhatsApp for home practice. Chair-based options are available for those with balance issues. Motivational support and tele-consultation by an oncology nurse provide ongoing guidance and symptom management to enhance self-efficacy in CIPN care.
Exercise educationBehavioural
Control group participants will receive an educational booklet and logbook, plus weekly WhatsApp exercise videos recommended by the Department of Health, HKSAR (Elderly Health Service, 2025) during the first six weeks. They are encouraged to follow NCCN and ACSM guidelines for cancer survivors: at least 150 minutes of moderate activity weekly, or 75 minutes vigorous, with warm-up and stretching before sessions. Stretching should occur on two non-resistance days, and resistance training 2-3 times weekly (2-3 sets of 10-15 reps, 2-3 minutes rest). For CIPN survivors, balance training is emphasized, with alternatives like cycling or water exercise. Encouragement messages follow in weeks 10 and 14.
| Study group | Role | What they receive |
|---|---|---|
| dance-based multimodal exercise | Experimental | Upon recruitment, participants will receive the exercise educational booklet and logbook. This study applies the Information-Motivation-Behavioral Skills (IMB) model in a six-week Zumba Gold dance program for cancer survivors. Each weekly 75-minute session includes vital sign checks, 50 minutes of multimodal exercise (warm-up, workout, cool-down), and group sharing. Dance styles taught are Merengue, Salsa, Cumbia, Belly dance, Flamenco, Tango, and cool-down, with revision in later sessions. Videos with safety guidance are shared via WhatsApp for home practice. Chair-based options are available for those with balance issues. Motivational support and tele-consultation by an oncology nurse provide ongoing guidance and symptom management to enhance self-efficacy in CIPN care. Receives: Behavioral: dance-based multimodal exercise |
| Exercise education | Active comparator | Control group participants will receive an educational booklet and logbook, plus weekly WhatsApp exercise videos recommended by the Department of Health, HKSAR (Elderly Health Service, 2025) during the first six weeks. They are encouraged to follow NCCN and ACSM guidelines for cancer survivors: at least 150 minutes of moderate activity weekly, or 75 minutes vigorous, with warm-up and stretching before sessions. Stretching should occur on two non-resistance days, and resistance training 2-3 times weekly (2-3 sets of 10-15 reps, 2-3 minutes rest). For CIPN survivors, balance training is emphasized, with alternatives like cycling or water exercise. Encouragement messages follow in weeks 10 and 14. Receives: Behavioral: Exercise education |
What is being measured
The primary outcome is the main question the study is designed to answer.
Chemotherapy-induced peripheral neuropathy.
In the main randomized control trial, the primary outcome is chemotherapy-induced peripheral neuropathy (CIPN). The Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity subscale (FACT/GOG-Ntx) subscale contains 11 items measuring the CIPN symptoms on a 5-point Likert scale (from 0= not at all to 4= very much) . A higher score indicates the worse CIPN symptoms .
Measured: from enrollment to 12 weeks after the intervention
Secondary outcomes (5)
Neuropathic pain
Douleur Neuropathique en 4 Questions (DN-4) contains ten items in four questions with dichotomous answers (Yes=1; No= 0) assessing the symptoms, associated symptoms and the aggregating factors of neuropathic pain in cancer patients.
Measured: from enrollment to 12 weeks after the intervention
Quality of Life in cancer patients
European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ C30) contains of 30 items assessing five functioning (physical, role, emotional, cognitive and social), nine symptom burdens (fatigue, nausea and vomiting, pain, dyspnea, insomnia, appetite loss, constipation, diarrhea and financial difficulties) and one global health status using 4-likert scale (from 1= not at all to 4= very much), except two items in global health status using the 7-point scale (from 1= very poor to 7= excellent) . Higher scores in functioning subscales indicate better functioning; while higher scores in symptom subscales indicate higher level of impairment .
Measured: from enrollment to 12 weeks after the intervention
Anxiety
Hospital Anxiety and Depression Scale (HADS) is a self-reported measure consisting of 14 items, in which seven of them assess the anxiety level. Higher scores in anxiety subscale indicate the higher level of anxiety. Individuals have borderline anxiety when the overall anxiety subscale is 8-10. It would be considered as anxiety if overall anxiety subscale above 11.
Measured: from enrollment to 12 weeks after intervention
Balance
Time up-to-go is used to assess cancer patients' gait and balance when changing positions from sitting to standing, turning, walking and from standing to sitting. The time taken that participants start from sitting on the chair, then standing and walking for 3m, followed by turning around and walking back, lastly sitting on the chair is recorded. Participants are asked to perform two trials. The quicker measurement is counted.
Measured: from enrollment to 12 weeks after intervention
Knowledge of exercise, exercise motivation and exercise self-efficacy
Perceived Physical Literacy Instrument (PPLI) contains nine items measuring knowledge and understanding, self-expression and communication with others, and sense of self and self-confidence (Sum et al., 2018). Participants rate each item using 5-point Likert scale (from 1= strongly disagree to 5=strongly agree). Higher scores indicate better knowledge, motivation and self-efficacy in exercise skills
Measured: from enrollment to 12 weeks after intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Jun 2026
- Study start1 Jun 2026 (estimated)
- Primary completion31 Dec 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (29)Papers the sponsor has linked to this study.
- Other trials for CancerStudies of the same condition, open and under way.
- More trials run by Chinese University of Hong KongThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 76 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Chinese University of Hong Kong
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Lau Ka Yan, Chinese University of Hong Kong
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07632482
- Sponsor's protocol ID
- 2026.192
- Status last verified
- Jun 2026
- First submitted
- 27 May 2026
- Last updated
- 8 Jun 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Zimmer P, Trebing S, Timmers-Trebing U, Schenk A, Paust R, Bloch W, Rudolph R, Streckmann F, Baumann FT. Eight-week, multimodal exercise counteracts a progress of chemotherapy-induced peripheral neuropathy and improves balance and strength in metastasized colorectal cancer patients: a randomized controlled trial. Support Care Cancer. 2018 Feb;26(2):615-624. doi: 10.1007/s00520-017-3875-5. Epub 2017 Sep 30.
PubMed 28963591Zhao H, Kanda K. Translation and validation of the standard Chinese version of the EORTC QLQ-C30. Qual Life Res. 2000 Mar;9(2):129-37. doi: 10.1023/a:1008981520920.
PubMed 10983477Wondie Y, Mehnert A, Hinz A. The Hospital Anxiety and Depression Scale (HADS) applied to Ethiopian cancer patients. PLoS One. 2020 Dec 3;15(12):e0243357. doi: 10.1371/journal.pone.0243357. eCollection 2020.
PubMed 33270779Whitehead AL, Julious SA, Cooper CL, Campbell MJ. Estimating the sample size for a pilot randomised trial to minimise the overall trial sample size for the external pilot and main trial for a continuous outcome variable. Stat Methods Med Res. 2016 Jun;25(3):1057-73. doi: 10.1177/0962280215588241. Epub 2015 Jun 19.
PubMed 26092476Wang YF, Yang CC, Ro LS, Tsai YC, Lin KP, Sun WZ, Fang WT, Wang SJ. Development and validation of a Taiwan version of the DN4-T questionnaire. J Chin Med Assoc. 2019 Aug;82(8):623-627. doi: 10.1097/JCMA.0000000000000129.
PubMed 31169589Sum RKW, Cheng CF, Wallhead T, Kuo CC, Wang FJ, Choi SM. Perceived physical literacy instrument for adolescents: A further validation of PPLI. J Exerc Sci Fit. 2018 Apr;16(1):26-31. doi: 10.1016/j.jesf.2018.03.002. Epub 2018 Mar 14.
PubMed 30662489Singer S, Kuhnt S, Gotze H, Hauss J, Hinz A, Liebmann A, Krauss O, Lehmann A, Schwarz R. Hospital anxiety and depression scale cutoff scores for cancer patients in acute care. Br J Cancer. 2009 Mar 24;100(6):908-12. doi: 10.1038/sj.bjc.6604952. Epub 2009 Feb 24.
PubMed 19240713Pergolizzi J Jr, LeQuang JAK, Coluzzi F, Magnusson P, Lara-Solares A, Varrassi G. Considerations for Pain Assessments in Cancer Patients: A Narrative Review of the Latin American Perspective. Cureus. 2023 Jun 22;15(6):e40804. doi: 10.7759/cureus.40804. eCollection 2023 Jun.
PubMed 37489190Oakley A, Strange V, Bonell C, Allen E, Stephenson J; RIPPLE Study Team. Process evaluation in randomised controlled trials of complex interventions. BMJ. 2006 Feb 18;332(7538):413-6. doi: 10.1136/bmj.332.7538.413.
PubMed 16484270Muller K, Karrer S, Szeimies RM, Steinbauer J, Kohl E, Steinbauer D, Zeman F, Berneburg M, Koller M. Quality of life assessment in patients with nonmelanoma skin cancer - psychometric validation of the EORTC QLQ-C30 questionnaire. J Dtsch Dermatol Ges. 2017 Nov;15(11):1090-1100. doi: 10.1111/ddg.13357.
PubMed 29106018Morse JM. Approaches to qualitative-quantitative methodological triangulation. Nurs Res. 1991 Mar-Apr;40(2):120-3. No abstract available.
PubMed 2003072Moore GF, Audrey S, Barker M, Bond L, Bonell C, Hardeman W, Moore L, O'Cathain A, Tinati T, Wight D, Baird J. Process evaluation of complex interventions: Medical Research Council guidance. BMJ. 2015 Mar 19;350:h1258. doi: 10.1136/bmj.h1258.
PubMed 25791983Li Q, Lin Y, Hu C, Xu Y, Zhou H, Yang L, Xu Y. The Chinese version of hospital anxiety and depression scale: Psychometric properties in Chinese cancer patients and their family caregivers. Eur J Oncol Nurs. 2016 Dec;25:16-23. doi: 10.1016/j.ejon.2016.09.004. Epub 2016 Sep 21.
PubMed 27865248Leung FH, Savithiri R. Spotlight on focus groups. Can Fam Physician. 2009 Feb;55(2):218-9. No abstract available.
PubMed 19221085Lantis K, Schnell P, Bland CR, Wilder J, Hock K, Vargo C, Glover NA, Hackney ME, Lustberg MB, Worthen-Chaudhari L. Biomechanical effect of neurologic dance training (NDT) for breast cancer survivors with chemotherapy-induced neuropathy: study protocol for a randomized controlled trial and preliminary baseline data. Trials. 2023 Sep 1;24(1):564. doi: 10.1186/s13063-023-07554-z.
PubMed 37658464
Study at a glance
From the registry record, last updated by the sponsor on 8 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Dance-based Multimodal Exercise Programme for Managing Chemotherapy-induced Peripheral Neuropathy in Patients With Solid Tumors: A Pilot Randomized Controlled Study
- ClinicalTrials.gov ID
- NCT07632482
- Acronym / sponsor ID
- 2026.192
- Conditions
- Cancer
- Keywords
- cancers, malignant solid tumors, chemotehrapy-induced peripheral neuropathy, CIPN
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 76 participants (estimated)
- Lead sponsor
- Chinese University of Hong KongUniversity, hospital or other
- Study start
- 1 Jun 2026 (estimated)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 8 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a significant and distressing symptom experienced by cancer patients with different cancer types. Systematic reviews demonstrate that exercise is an effective non-pharmacological strategy for managing chemotherapy-induced peripheral neuropathy (CIPN) in cancer patients. Multimodal exercise was found to be superior to a single-modality exercise programme. However, the lack of using Information-Motivation-Behavioral Skill (IMB) model and addressing the social motivation component in current multimodal exercise programmes for cancer patients with solid tumors.
Objectives: This study aims to evaluate the effects of a 6-week dance-based multimodal exercise program on CIPN symptoms over a 3-month period, comparing outcomes with usual care in cancer patients with solid tumors.
Methods: An assessor-blinded pilot randomized controlled trial with process evaluation will be conducted at Community Cancer Centers/ Community Centers and Non-governmental organizations. A total of 76 participants will be recruited, with both intervention and control groups receiving educational booklets and logbooks. The intervention group will engage in a 6-week dance-based multimodal exercise program, supplemented by goal-setting evaluations and motivational messaging. The control group will receive weekly exercise videos and motivational messages. Outcomes, including CIPN severity, quality of life, pain, balance, exercise knowledge, motivation, self-efficacy, and adverse effects, will be measured using validated tools at baseline, immediately post-intervention, 4 weeks post-intervention, and 12 weeks post-intervention. Process evaluation will explore perceived benefits, program awareness, and facilitators and barriers to adherence.
Conclusion: This study aims to provide an evidence-based approach for managing CIPN in cancer patients through a dance-based multimodal exercise program. It underscores the importance of incorporating the IMB model to enhance exercise adherence and support self-management of CIPN in cancer survivors.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| dance-based multimodal exercise | Experimental | Behavioral: dance-based multimodal exerciseUpon recruitment, participants will receive the exercise educational booklet and logbook. This study applies the Information-Motivation-Behavioral Skills (IMB) model in a six-week Zumba Gold dance program for cancer survivors. Each weekly 75-minute session includes vital sign checks, 50 minutes of multimodal exercise (warm-up, workout, cool-down), and group sharing. Dance styles taught are Merengue, Salsa, Cumbia, Belly dance, Flamenco, Tango, and cool-down, with revision in later sessions. Videos with safety guidance are shared via WhatsApp for home practice. Chair-based options are available for those with balance issues. Motivational support and tele-consultation by an oncology nurse provide ongoing guidance and symptom management to enhance self-efficacy in CIPN care. |
| Exercise education | Active comparator | Behavioral: Exercise educationControl group participants will receive an educational booklet and logbook, plus weekly WhatsApp exercise videos recommended by the Department of Health, HKSAR (Elderly Health Service, 2025) during the first six weeks. They are encouraged to follow NCCN and ACSM guidelines for cancer survivors: at least 150 minutes of moderate activity weekly, or 75 minutes vigorous, with warm-up and stretching before sessions. Stretching should occur on two non-resistance days, and resistance training 2-3 times weekly (2-3 sets of 10-15 reps, 2-3 minutes rest). For CIPN survivors, balance training is emphasized, with alternatives like cycling or water exercise. Encouragement messages follow in weeks 10 and 14. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Patients was diagnosed with malignant solid tumor (s) which is defined as abnormal, cancerous masses of tissue, for example, all carcinomas (such as breast cancer, stomach cancer, colorectal cancer and gynecological cancer, lung cancer and so on), sarcomas and lymphomas
- Patients experience CIPN symptoms
- Patients are able to use smart phone and WhatsApp
- Patients are able to read or understand Chinese.
Key exclusion criteria (5 listed)
- Cancer patients suffer from severe organ failure or diseases that limit their level of activity
- Patients are diagnosed with non-chemotherapy induced peripheral neuropathy, such as sciatica and diabetic neuropathy
- Patients receive treatments that affect the severity of neuropathy, such as steroid, anticonvulsants and antidepressants
- Patients age below 18 years old
- Patients have cognitive impairments.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| dance-based multimodal exerciseThis study applies the Information-Motivation-Behavioral Skills (IMB) model in a six-week Zumba Gold dance program for cancer survivors. Each weekly 75-minute session includes vital sign checks, 50 minutes of multimodal exercise (warm-up, workout, cool-down), and group sharing. Dance styles taught are Merengue, Salsa, Cumbia, Belly dance, Flamenco, Tango, and cool-down, with revision in later sessions. Videos with safety guidance are shared via WhatsApp for home practice. Chair-based options are available for those with balance issues. Motivational support and tele-consultation by an oncology nurse provide ongoing guidance and symptom management to enhance self-efficacy in CIPN care. | Behavioural | dance-based multimodal exercise |
| Exercise educationControl group participants will receive an educational booklet and logbook, plus weekly WhatsApp exercise videos recommended by the Department of Health, HKSAR (Elderly Health Service, 2025) during the first six weeks. They are encouraged to follow NCCN and ACSM guidelines for cancer survivors: at least 150 minutes of moderate activity weekly, or 75 minutes vigorous, with warm-up and stretching before sessions. Stretching should occur on two non-resistance days, and resistance training 2-3 times weekly (2-3 sets of 10-15 reps, 2-3 minutes rest). For CIPN survivors, balance training is emphasized, with alternatives like cycling or water exercise. Encouragement messages follow in weeks 10 and 14. | Behavioural | Exercise education |
Primary outcome
Chemotherapy-induced peripheral neuropathy.
Time frame: from enrollment to 12 weeks after the intervention
In the main randomized control trial, the primary outcome is chemotherapy-induced peripheral neuropathy (CIPN). The Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity subscale (FACT/GOG-Ntx) subscale contains 11 items measuring the CIPN symptoms on a 5-point Likert scale (from 0= not at all to 4= very much) . A higher score indicates the worse CIPN symptoms .
5 secondary outcomes
Neuropathic pain
Time frame: from enrollment to 12 weeks after the intervention
Quality of Life in cancer patients
Time frame: from enrollment to 12 weeks after the intervention
Anxiety
Time frame: from enrollment to 12 weeks after intervention
Balance
Time frame: from enrollment to 12 weeks after intervention
Knowledge of exercise, exercise motivation and exercise self-efficacy
Time frame: from enrollment to 12 weeks after intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Jun 2026.
- Background: PubMed 28963591Zimmer P, Trebing S, Timmers-Trebing U, Schenk A, Paust R, Bloch W, Rudolph R, Streckmann F, Baumann FT. Eight-week, multimodal exercise counteracts a progress of chemotherapy-induced peripheral neuropathy and improves balance and strength in metastasized colorectal cancer patients: a randomized controlled trial. Support Care Cancer. 2018 Feb;26(2):615-624. doi: 10.1007/s00520-017-3875-5. Epub 2017 Sep 30.
- Background: PubMed 10983477Zhao H, Kanda K. Translation and validation of the standard Chinese version of the EORTC QLQ-C30. Qual Life Res. 2000 Mar;9(2):129-37. doi: 10.1023/a:1008981520920.
- Background: PubMed 33270779Wondie Y, Mehnert A, Hinz A. The Hospital Anxiety and Depression Scale (HADS) applied to Ethiopian cancer patients. PLoS One. 2020 Dec 3;15(12):e0243357. doi: 10.1371/journal.pone.0243357. eCollection 2020.
- Background: PubMed 26092476Whitehead AL, Julious SA, Cooper CL, Campbell MJ. Estimating the sample size for a pilot randomised trial to minimise the overall trial sample size for the external pilot and main trial for a continuous outcome variable. Stat Methods Med Res. 2016 Jun;25(3):1057-73. doi: 10.1177/0962280215588241. Epub 2015 Jun 19.
- Background: PubMed 31169589Wang YF, Yang CC, Ro LS, Tsai YC, Lin KP, Sun WZ, Fang WT, Wang SJ. Development and validation of a Taiwan version of the DN4-T questionnaire. J Chin Med Assoc. 2019 Aug;82(8):623-627. doi: 10.1097/JCMA.0000000000000129.
- Background: PubMed 30662489Sum RKW, Cheng CF, Wallhead T, Kuo CC, Wang FJ, Choi SM. Perceived physical literacy instrument for adolescents: A further validation of PPLI. J Exerc Sci Fit. 2018 Apr;16(1):26-31. doi: 10.1016/j.jesf.2018.03.002. Epub 2018 Mar 14.
- Background: PubMed 19240713Singer S, Kuhnt S, Gotze H, Hauss J, Hinz A, Liebmann A, Krauss O, Lehmann A, Schwarz R. Hospital anxiety and depression scale cutoff scores for cancer patients in acute care. Br J Cancer. 2009 Mar 24;100(6):908-12. doi: 10.1038/sj.bjc.6604952. Epub 2009 Feb 24.
- Background: PubMed 37489190Pergolizzi J Jr, LeQuang JAK, Coluzzi F, Magnusson P, Lara-Solares A, Varrassi G. Considerations for Pain Assessments in Cancer Patients: A Narrative Review of the Latin American Perspective. Cureus. 2023 Jun 22;15(6):e40804. doi: 10.7759/cureus.40804. eCollection 2023 Jun.
- Background: PubMed 16484270Oakley A, Strange V, Bonell C, Allen E, Stephenson J; RIPPLE Study Team. Process evaluation in randomised controlled trials of complex interventions. BMJ. 2006 Feb 18;332(7538):413-6. doi: 10.1136/bmj.332.7538.413.
- Background: PubMed 29106018Muller K, Karrer S, Szeimies RM, Steinbauer J, Kohl E, Steinbauer D, Zeman F, Berneburg M, Koller M. Quality of life assessment in patients with nonmelanoma skin cancer - psychometric validation of the EORTC QLQ-C30 questionnaire. J Dtsch Dermatol Ges. 2017 Nov;15(11):1090-1100. doi: 10.1111/ddg.13357.
- Background: PubMed 2003072Morse JM. Approaches to qualitative-quantitative methodological triangulation. Nurs Res. 1991 Mar-Apr;40(2):120-3. No abstract available.
- Background: PubMed 25791983Moore GF, Audrey S, Barker M, Bond L, Bonell C, Hardeman W, Moore L, O'Cathain A, Tinati T, Wight D, Baird J. Process evaluation of complex interventions: Medical Research Council guidance. BMJ. 2015 Mar 19;350:h1258. doi: 10.1136/bmj.h1258.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing dance-based multimodal exercise and Exercise education in people with Cancer, run by Chinese University of Hong Kong.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 8 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ka Yan Lau (+852 37024260, 1007615222@link.cuhk.edu.hk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Chemotherapy-induced peripheral neuropathy. (time frame: from enrollment to 12 weeks after the intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07632482, which also lists 29 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jun 2026.