Physical FitnessNCT07628478
Effects of Blood Flow Restriction Training on Body Composition and Maximal Strength in Military Personnel
A study testing KAATSU Master Pneumatic Cuff and High-Load Resistance Training in people with Physical Fitness and Muscle Strength, run by Yang Liu at 1 site in China.
Trial summary
This study aims to compare the effects of low-intensity blood flow restriction training combined with resistance training versus traditional high-intensity resistance training on body composition (skeletal muscle mass, body fat mass) and maximal strength (isometric mid-thigh pull, vertical jump, isometric squat pull)… Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Physical Fitness, Muscle Strength, Body Composition
- What is being tested?
- KAATSU Master Pneumatic Cuff and High-Load Resistance Training
- Type of treatment
- Medical device, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 1 siteChina
- Study dates
- 1 Jun 2026to 28 Jul 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- Male cadets from military academy;
- No contraindications to blood flow restriction training (no circulatory diseases, skin allergies);
- Healthy and capable of high-intensity exercise;
- Signed informed consent
Who cannot join
- Major sports injury within 2 years (fracture, ligament tear, muscle/tendon rupture, habitual joint dislocation);
- Cardiovascular or visceral organ diseases;
- Other conditions unsuitable for training
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Blood Flow Restriction Training on Body Composition and Maximal Strength in Military Personnel: A Prospective Randomized Controlled Trial
This study aims to compare the effects of low-intensity blood flow restriction training combined with resistance training versus traditional high-intensity resistance training on body composition (skeletal muscle mass, body fat mass) and maximal strength (isometric mid-thigh pull, vertical jump, isometric squat pull) in male military academy cadets. The study lasts for 6 weeks and adopts a randomized parallel-group design.
- Conditions
- Physical Fitness, Muscle Strength, Body Composition
- Being tested
- KAATSU Master Pneumatic Cuff, High-Load Resistance Training
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
KAATSU Master Pneumatic CuffDevice
Pneumatic pressure cuffs applied to the proximal thigh at 200 mmHg to achieve partial blood flow restriction during low-load resistance training (30% 1RM). Initial warm-up at 40 mmHg.
High-Load Resistance TrainingBehavioural
Traditional resistance training at 70% of one-repetition maximum (1RM) without blood flow restriction.
| Study group | Role | What they receive |
|---|---|---|
| Low-Load Blood Flow Restistance Training (LL-BFR) | Experimental | Participants perform low-load resistance training (30% 1RM) combined with blood flow restriction. Lower extremity exercises include squat, deadlift, weighted lunge, and resisted running. Pneumatic cuffs (KAATSU Master) are applied at the proximal thigh at 200 mmHg during exercise and rest intervals. Training: 1 set of 30 reps, followed by 3 sets of 15 reps; 60-second rest between sets; 3 days/week for 6 weeks. Receives: Device: KAATSU Master Pneumatic Cuff |
| Traditional High-Load Resistance Training (HL-RT) | Active comparator | Participants perform traditional high-load resistance training at 70% 1RM. Same exercises as experimental group: squat, deadlift, weighted lunge, and resisted running. 4 sets of 8-12 reps; 3-minute rest between sets; 3 days/week for 6 weeks. Receives: Behavioral: High-Load Resistance Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Peak Force in Isometric Mid-Thigh Pull (IMTP)
Maximal vertical ground reaction force during isometric mid-thigh pull measured on ELIGA portable force plate. Participants pull a fixed bar with knee angle 125°-135° for 3-5 seconds. Best of 2 trials recorded in Newtons (N).
Measured: Baseline (T1), Week 3 (T2), Week 6 (T3)
Secondary outcomes (2)
Countermovement Jump Height (CMJ)
Vertical jump height calculated from flight time measured on ELIGA portable force plate. Formula: height = g × t²/8, where g = 9.81 m/s². Hands on hips, self-selected countermovement depth. Best of 3 trials in centimeters (cm).
Measured: Baseline (T1), Week 6 (T3)
Body Fat Mass
Total body fat mass measured by bioelectrical impedance analysis (InBody). Expressed in kilograms (kg).
Measured: Baseline (T1), Week 6 (T3)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Jun 2026
- Study start1 Jun 2026
- Primary completion20 Jul 2026
- Study completion28 Jul 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Physical FitnessStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 36 participants (actual)
Sponsor and investigators
- Lead sponsor
- Yang Liu
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Yang Liu, Wuhan Sports University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07628478
- Sponsor's protocol ID
- 2026069
- Status last verified
- Jun 2026
- First submitted
- 29 May 2026
- Last updated
- 6 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Publications
Yang K, Chee CS, Abdul Kahar J, Tengku Kamalden TF, Li R, Qian S. Effects of blood flow restriction training on physical fitness among athletes: a systematic review and meta-analysis. Sci Rep. 2024 Jul 18;14(1):16615. doi: 10.1038/s41598-024-67181-9.
PubMed 39025894
Study at a glance
From the registry record, last updated by the sponsor on 6 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Blood Flow Restriction Training on Body Composition and Maximal Strength in Military Personnel: A Prospective Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07628478
- Acronym / sponsor ID
- 2026069
- Conditions
- Physical Fitness, Muscle Strength, Body Composition
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 36 participants (actual)
- Lead sponsor
- Yang LiuUniversity, hospital or other
- Study start
- 1 Jun 2026 (actual)
- Primary completion
- 20 Jul 2026 (actual)
- Study completion
- 28 Jul 2026 (actual)
- First posted
- 5 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to compare the effects of low-intensity blood flow restriction training combined with resistance training versus traditional high-intensity resistance training on body composition (skeletal muscle mass, body fat mass) and maximal strength (isometric mid-thigh pull, vertical jump, isometric squat pull) in male military academy cadets. The study lasts for 6 weeks and adopts a randomized parallel-group design.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Low-Load Blood Flow Restistance Training (LL-BFR) | Experimental | Device: KAATSU Master Pneumatic CuffParticipants perform low-load resistance training (30% 1RM) combined with blood flow restriction. Lower extremity exercises include squat, deadlift, weighted lunge, and resisted running. Pneumatic cuffs (KAATSU Master) are applied at the proximal thigh at 200 mmHg during exercise and rest intervals. Training: 1 set of 30 reps, followed by 3 sets of 15 reps; 60-second rest between sets; 3 days/week for 6 weeks. |
| Traditional High-Load Resistance Training (HL-RT) | Active comparator | Behavioral: High-Load Resistance TrainingParticipants perform traditional high-load resistance training at 70% 1RM. Same exercises as experimental group: squat, deadlift, weighted lunge, and resisted running. 4 sets of 8-12 reps; 3-minute rest between sets; 3 days/week for 6 weeks. |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (4 listed)
- Male cadets from military academy;
- No contraindications to blood flow restriction training (no circulatory diseases, skin allergies);
- Healthy and capable of high-intensity exercise;
- Signed informed consent
Key exclusion criteria (3 listed)
- Major sports injury within 2 years (fracture, ligament tear, muscle/tendon rupture, habitual joint dislocation);
- Cardiovascular or visceral organ diseases;
- Other conditions unsuitable for training
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| KAATSU Master Pneumatic CuffPneumatic pressure cuffs applied to the proximal thigh at 200 mmHg to achieve partial blood flow restriction during low-load resistance training (30% 1RM). Initial warm-up at 40 mmHg. | Device | Low-Load Blood Flow Restistance Training (LL-BFR) |
| High-Load Resistance TrainingTraditional resistance training at 70% of one-repetition maximum (1RM) without blood flow restriction. | Behavioural | Traditional High-Load Resistance Training (HL-RT) |
Primary outcome
Peak Force in Isometric Mid-Thigh Pull (IMTP)
Time frame: Baseline (T1), Week 3 (T2), Week 6 (T3)
Maximal vertical ground reaction force during isometric mid-thigh pull measured on ELIGA portable force plate. Participants pull a fixed bar with knee angle 125°-135° for 3-5 seconds. Best of 2 trials recorded in Newtons (N).
2 secondary outcomes
Countermovement Jump Height (CMJ)
Time frame: Baseline (T1), Week 6 (T3)
Body Fat Mass
Time frame: Baseline (T1), Week 6 (T3)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Nov 2026.
- Background: PubMed 39025894Yang K, Chee CS, Abdul Kahar J, Tengku Kamalden TF, Li R, Qian S. Effects of blood flow restriction training on physical fitness among athletes: a systematic review and meta-analysis. Sci Rep. 2024 Jul 18;14(1):16615. doi: 10.1038/s41598-024-67181-9.
- Related InfoLink provided by the sponsor.
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing KAATSU Master Pneumatic Cuff and High-Load Resistance Training in people with Physical Fitness and Muscle Strength, run by Yang Liu at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Peak Force in Isometric Mid-Thigh Pull (IMTP) (time frame: Baseline (T1), Week 3 (T2), Week 6 (T3)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07628478, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Nov 2026.