Depression and Anxiety SymptomsNCT07611253
The Effect of Loving-Kindness Meditation on Mood and Anxiety Symptoms, Interpersonal Relationships, and Emotions: An Initial Randomized Controlled Trial With a Non-Clinical Sample of Undergraduate Women
A study testing Loving-Kindness Meditation and Visualization in people with Depression and Anxiety Symptoms, run by Luis Flores at 1 site in Canada.
Trial summary
The goal of this clinical trial was to examine the effects of Loving-Kindness Meditation (LKM) on anhedonic depressivity, interpersonal relationships (other inclusive self-concept, willingness to sacrifice, interaction quality) and emotions (positive affect, negative affect). Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Depression and Anxiety Symptoms
- What is being tested?
- Loving-Kindness Meditation and Visualization
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 240 participants
- Where
- 1 siteCanada
- Study dates
- 13 Jan 2021to 11 Apr 2021
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Participants must be enrolled as an undergraduate student
- Each Participant had to self-identify as a woman.
- Participants had to be age 18 or older.
- Participants had to have at least one close female platonic friend.
Who cannot join
- Participants did not complete at least three of seven daily meditations.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effect of Loving-Kindness Meditation on Anhedonic Depressivity, Interpersonal Relationships, and Emotions.
The goal of this clinical trial was to examine the effects of Loving-Kindness Meditation (LKM) on anhedonic depressivity, interpersonal relationships (other inclusive self-concept, willingness to sacrifice, interaction quality) and emotions (positive affect, negative affect).
The second aim was to conduct exploratory analyses investigating potential mediators that help explain changes in anhedonic depressivity over the course of short-term targeted LKM.
Participants were randomly assigned to receive one week of ~5-minute daily audio recordings of Loving-Kindness Meditation or a visualization meditation, both of which were focused on a same-gender close friend. Participants completed baseline and follow-up questionnaires measuring psychological, social, and emotional variables; participants also completed daily questionnaires.
Read the detailed description
Undergraduate women were recruited via the Queen's University psychology department's subject pool (n = 222) and online advertisements (i.e., Facebook; n = 18) in 2021; written informed consent was obtained from all participants prior to any data collection.
We randomly assigned participants-via Microsoft Excel random number generation-to engage in one-week of either a targeted form of Loving-Kindness Meditation or a visualization meditation. Participants identified a specific close friend at the beginning of the study to be the target of their meditation practice. They completed baseline and one-week follow-up measures.
Audio instructions for the LKM and visualization meditation conditions were developed for this study based on those used by Seppala et al. (2014). Recordings were delivered via email. Descriptions of the conditions can be found in the Arms and Interventions sections.
- Conditions
- Depression and Anxiety Symptoms
- Being tested
- Loving-Kindness Meditation, Visualization
- Keywords
- Meditation, Anhedonic Depression, Social Relationships, Positive Affect, Inclusion of the Other in the Self Scale, Loving-Kindness Meditation, Willingness to Sacrifice, Negative Affect, Rochester Interaction Record
- Medical subject headings
- Depression, Anxiety Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Loving-Kindness MeditationBehavioural
Participants received a ~5 minute audio recording of Loving-Kindness Meditation Instructions everday for one week. Recordings were delivered via email. Meditators in both conditions were instructed to find a comfortable position, either sitting or lying down, and were then guided through some initial deep breathing. Once relaxed, meditators in the LKM condition were asked to imagine receiving love and wishes of well-being from a close other; they were then asked to direct feelings of love and wishes of wellness to their target close friend. After approximately 5 minutes, meditators were guided back to relaxation.
VisualizationBehavioural
Participants received a ~5 minute audio recording of visualization Instructions everday for one week. Recordings were delivered via email. Meditators in both conditions were instructed to find a comfortable position, either sitting or lying down, and were then guided through some initial deep breathing. Meditators in the visualization condition were asked to visualize specific details of their target close friend's appearance. After approximately 5 minutes, meditators were guided back to relaxation.
| Study group | Role | What they receive |
|---|---|---|
| Loving-Kindness Meditation | Experimental | Participants randomly assigned (via Microsoft Excel) to receive the Loving-Kindness Meditation intervention. Receives: Behavioral: Loving-Kindness Meditation |
| Visualization Meditation | Active comparator | Participants randomly assigned (via Microsoft Excel) to receive the Visualization Meditation active comparator condition. Receives: Behavioral: Visualization |
What is being measured
The primary outcome is the main question the study is designed to answer.
Anhedonic Depressivity
The anhedonic depression scale of the Mood and Anxiety Symptom Questionnaire (MASQ; Clark \& Watson, 1991) was used to measure anhedonic depressivity. Participants rated items of the MASQ (Clark \& Watson, 1991) on a scale from 1-5 (1 = Not at All; 5 = Extremely) based on how they felt over the past week. The anhedonic depression subscale includes 22 items (e.g., "Felt like there wasn't anything interesting or fun to do"). A mean score was calculated, with higher scores indicating more anhedonic depressivity.
Measured: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Secondary outcomes (9)
Positive Affect
The Positive Affect Negative Affect Schedule (PANAS; Watson et al., 1988) was used to measure positive affect. The PANAS consists of 20 emotion words divided into two subscales (10 positive words and 10 negative words). Participants rate each emotion word on a scale from 1-5 (1 = Very Slightly or Not at All; 5 = Extremely) corresponding to how they have been feeling over the past week. The positive affect subscale contains emotion words such as: "Interested," "Excited," and "Inspired." A mean score was calculated for use in data analyses, with higher scores indicating greater positive affect.
Measured: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Willingness to Sacrifice
The willingness to sacrifice scale is a two-item measure adapted from the Marburg Attitude Inventory for Styles of Loving (Bierhoff et al., 1993). Participants are asked to respond to the following questions on a scale from 1-10 (1 = Not at all; 10 = Entirely): "To what extent would you be willing to sacrifice your own desires for your close friend's desires?"; and "To what extent would you leave everything else aside for your close friend?". At baseline and follow-up, participants responded to these questions based on the previous week. For each administration, a mean score was calculated for use in data analyses.
Measured: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Other-Inclusive Self Concept
The Inclusion of the Other in the Self Scale (IOS; Aron et al., 1992) is a one item measure composed of seven images of two increasingly overlapping circles labeled "self" and "other". Other-inclusive self-concept was measured with a modified IOS by asking participants to think about their relationship with their chosen close friend over the past week and to indicate the diagram that best matched their perceived connection. The IOS has convergent validity (Aron et al., 1992; Gächter et al., 2015) and discriminant validity (Aron et al., 1992) in relation to other established interpersonal closeness measures.
Measured: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Interaction Quality
A modified version of the Rochester Interaction Record (M-RIR; based on Wheeler \& Reis, 1991) was used to measure interaction quality. The M-RIR asks participants to rate, from 1-7, the degree to which their interactions with their close other: 1) were intimate (1 = superficial; 7 = meaningful); 2) included self/other disclosure (1 = very little; 7 = a great deal); 3) were satisfying (1 = very unsatisfying; 7 = very satisfying); 4) were loving (1 = not at all loving; 7 = very loving); 5) were supportive (1 = not at all supportive; 7 = very supportive); and 6) were stressful (1 = not at all stressful; 7 = very stressful; reverse coded). At baseline and follow-up, participants completed the M-RIR for the past week. A mean score was calculated for use in data analyses, with higher scores indicating greater interaction quality.
Measured: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Anxious Arousal
The anxious arousal subscale of the Mood and Anxiety Symptom Questionnaire (MASQ; Clark \& Watson, 1991) was used to measure anxious arousal.
Participants rated items of the MASQ (Clark \& Watson, 1991) on a scale from 1-5 (1 = Not at All; 5 = Extremely) based on how they felt over the past week. The anxious arousal subscale includes 17 items (e.g., "Was trembling or shaking"). For each subscale, a mean score was calculated, with higher scores indicating more anxious arousal.
Measured: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Negative Affect
The Positive Affect Negative Affect Schedule (PANAS; Watson et al., 1988) was used to measure negative affect. The PANAS consists of 20 emotion words divided into two subscales (10 positive words and 10 negative words). Participants rate each emotion word on a scale from 1-5 (1 = Very Slightly or Not at All; 5 = Extremely) corresponding to how they have been feeling over the past week. The negative affect subscale contains emotion words such as "Hostile", "Irritable", and "Ashamed'". A mean score was calculated for use in data analyses, with higher scores indicating greater negative affect.
Measured: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Emotional Closeness
Emotional closeness was measured using a modified 10-item version of the Emotional Closeness Questionnaire (ECQ; Flores \& Berenbaum, 2012, 2014). The ECQ presents participants with 10 statements that reflect aspects of emotional closeness (e.g., "my friend gave me emotional support", "I shared my personal thoughts or feelings with my friend"). Respondents rate the degree each of these statements happened over the past week on a scale of 1 (not at all) to 5 (extremely). Scores from each question are averaged to create an overall score with higher scores indicating higher levels of emotional closeness (Flores \& Berenbaum, 2012, 2014). This questionnaire was modified to ask respondents to specifically consider the close other they chose at the beginning of the study.
Measured: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Desired Emotional Closeness
Desired emotional closeness was measured using a modified 10-item version of the Emotional Closeness Questionnaire (ECQ; Flores \& Berenbaum, 2012, 2014). The D-ECQ presents participants with 5 statements that reflect aspects of emotional closeness (e.g., "my friend gives me emotional support", "I share my personal thoughts or feelings with my friend"). Respondents rate the degree to which they would have liked each of these statements to have happened over the past week on a scale of 1 (not at all) to 5 (extremely). Scores from each question are averaged to create an overall score with higher scores indicating a higher desire for emotional closeness (Flores \& Berenbaum, 2012, 2014). This questionnaire was modified to ask respondents to specifically consider the close other they chose at the beginning of the study.
Measured: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Worry
The Penn State Worry Questionnaire (PSWQ; Meyer et al., 1990) was used to measure worry. The PSWQ asks participants to rate the degree to which 16 statements related to worry are typical or characteristic of them (e.g., "My worries overwhelm me", "Once I start worrying, I can't stop"). Respondents rate each item on a scale from 1 (not at all typical) to 5 (very typical; Meyer et al., 1990). A mean score was generated for each participant with higher scores indicating higher levels of worry.
Measured: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 May 2026
- Study start13 Jan 2021
- Primary completion11 Apr 2021
- Study completion11 Apr 2021
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (13)Papers the sponsor has linked to this study.
- Other trials for Depression and Anxiety SymptomsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 240 participants (actual)
Sponsor and investigators
- Lead sponsor
- Luis Flores
- Sponsor type
- University, hospital or other
- Collaborators
- Social Sciences and Humanities Research Council of Canada
- Responsible party
- Sponsor-investigator, Luis Flores, Queen's University
- Investigators
- Luis Flores, Ph.D., Principal investigator, Queen's University and Rutgers University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07611253
- Sponsor's protocol ID
- rf#1025416
- Status last verified
- May 2026
- First submitted
- 1 May 2026
- Last updated
- 28 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Deidentified participant data will be shared on Open Science Framework. Only IPD used in the results publication will be shared.
Publications
Flores Jr, L. E., & Berenbaum, H. (2014). Desired emotional closeness moderates the prospective relations between levels of perceived emotional closeness and psychological distress. Journal of Social and Clinical Psychology, 33(8), 673-700. https://doi.org/10.1521/jscp.2014.33.8.673
Flores Jr, L. E., & Berenbaum, H. (2012). Desire for emotional closeness moderates the effectiveness of the social regulation of emotion. Personality and Individual Differences, 53(8), 952-957. https://doi.org/10.1016/j.paid.2012.07.009
Meyer TJ, Miller ML, Metzger RL, Borkovec TD. Development and validation of the Penn State Worry Questionnaire. Behav Res Ther. 1990;28(6):487-95. doi: 10.1016/0005-7967(90)90135-6.
PubMed 2076086Hayes, A. F. (2018). Introduction to mediation, moderation, and conditional process analysis: A regression-based approach (2nd ed.) Guilford publications.
Hayes, A. F. (2012). PROCESS: A versatile computational tool for observed variable mediation, moderation, and conditional process modeling [White paper]. Retrieved from http://www.afhayes.com/public/process2012.pdf
Trautwein FM, Naranjo JR, Schmidt S. Decentering the Self? Reduced Bias in Self- vs. Other-Related Processing in Long-Term Practitioners of Loving-Kindness Meditation. Front Psychol. 2016 Nov 21;7:1785. doi: 10.3389/fpsyg.2016.01785. eCollection 2016.
PubMed 27917136Bierhoff, H. W., Grau, I., & Ludwig, A. (1993). Marburger Einstellungsinventar zu Liebesstilen (MEIL). Hogrefe.
Wheeler, L., & Reis, H. T., (1991). Self-recording of everyday life events: Origins, types, and uses. Journal of Personality, 59, 339-354. doi:10.1111/j.1467-6494.1991.tb00252.x
Aron, A., Aron, E. N., & Smollan, D. (1992). Inclusion of the other in the self scale and the structure of interpersonal closeness. Journal of Personality and Social Psychology, 63(4), 596-612. https://doi.org/10.1037/0022-3514.63.4.596
Seppala, E.M., Hutcherson, C.A., Nguyen, D.T., Hutcheson, C. A., & Gross, J. J. (2014). Loving-kindness meditation: A tool to improve healthcare provider compassion, resilience, and patient care. Journal of Compassionate Health Care, 1(1), 1-9. https://doi.org/10.1186/s40639-014-0005-9
Gachter S, Starmer C, Tufano F. Measuring the Closeness of Relationships: A Comprehensive Evaluation of the 'Inclusion of the Other in the Self' Scale. PLoS One. 2015 Jun 12;10(6):e0129478. doi: 10.1371/journal.pone.0129478. eCollection 2015.
PubMed 26068873Watson D, Clark LA, Tellegen A. Development and validation of brief measures of positive and negative affect: the PANAS scales. J Pers Soc Psychol. 1988 Jun;54(6):1063-70. doi: 10.1037//0022-3514.54.6.1063.
PubMed 3397865Clark LA, Watson D. Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications. J Abnorm Psychol. 1991 Aug;100(3):316-36. doi: 10.1037//0021-843x.100.3.316.
PubMed 1918611
Study at a glance
From the registry record, last updated by the sponsor on 28 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Loving-Kindness Meditation on Anhedonic Depressivity, Interpersonal Relationships, and Emotions.
- ClinicalTrials.gov ID
- NCT07611253
- Acronym / sponsor ID
- rf#1025416
- Conditions
- Depression and Anxiety Symptoms
- Keywords
- Meditation, Anhedonic Depression, Social Relationships, Positive Affect, Inclusion of the Other in the Self Scale, Loving-Kindness Meditation, Willingness to Sacrifice, Negative Affect
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 240 participants (actual)
- Lead sponsor
- Luis FloresUniversity, hospital or other
- Collaborators
- Social Sciences and Humanities Research Council of Canada
- Study start
- 13 Jan 2021 (actual)
- Primary completion
- 11 Apr 2021 (actual)
- Study completion
- 11 Apr 2021 (actual)
- First posted
- 28 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial was to examine the effects of Loving-Kindness Meditation (LKM) on anhedonic depressivity, interpersonal relationships (other inclusive self-concept, willingness to sacrifice, interaction quality) and emotions (positive affect, negative affect).
The second aim was to conduct exploratory analyses investigating potential mediators that help explain changes in anhedonic depressivity over the course of short-term targeted LKM.
Participants were randomly assigned to receive one week of ~5-minute daily audio recordings of Loving-Kindness Meditation or a visualization meditation, both of which were focused on a same-gender close friend. Participants completed baseline and follow-up questionnaires measuring psychological, social, and emotional variables; participants also completed daily questionnaires.
Detailed description
Undergraduate women were recruited via the Queen's University psychology department's subject pool (n = 222) and online advertisements (i.e., Facebook; n = 18) in 2021; written informed consent was obtained from all participants prior to any data collection.
We randomly assigned participants-via Microsoft Excel random number generation-to engage in one-week of either a targeted form of Loving-Kindness Meditation or a visualization meditation. Participants identified a specific close friend at the beginning of the study to be the target of their meditation practice. They completed baseline and one-week follow-up measures.
Audio instructions for the LKM and visualization meditation conditions were developed for this study based on those used by Seppala et al. (2014). Recordings were delivered via email. Descriptions of the conditions can be found in the Arms and Interventions sections.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Loving-Kindness Meditation | Experimental | Behavioral: Loving-Kindness MeditationParticipants randomly assigned (via Microsoft Excel) to receive the Loving-Kindness Meditation intervention. |
| Visualization Meditation | Active comparator | Behavioral: VisualizationParticipants randomly assigned (via Microsoft Excel) to receive the Visualization Meditation active comparator condition. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Participants must be enrolled as an undergraduate student
- Each Participant had to self-identify as a woman.
- Participants had to be age 18 or older.
- Participants had to have at least one close female platonic friend.
Key exclusion criteria (1 listed)
- Participants did not complete at least three of seven daily meditations.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Loving-Kindness MeditationParticipants received a ~5 minute audio recording of Loving-Kindness Meditation Instructions everday for one week. Recordings were delivered via email. Meditators in both conditions were instructed to find a comfortable position, either sitting or lying down, and were then guided through some initial deep breathing. Once relaxed, meditators in the LKM condition were asked to imagine receiving love and wishes of well-being from a close other; they were then asked to direct feelings of love and wishes of wellness to their target close friend. After approximately 5 minutes, meditators were guided back to relaxation. | Behavioural | Loving-Kindness Meditation |
| VisualizationParticipants received a ~5 minute audio recording of visualization Instructions everday for one week. Recordings were delivered via email. Meditators in both conditions were instructed to find a comfortable position, either sitting or lying down, and were then guided through some initial deep breathing. Meditators in the visualization condition were asked to visualize specific details of their target close friend's appearance. After approximately 5 minutes, meditators were guided back to relaxation. | Behavioural | Visualization Meditation |
Primary outcome
Anhedonic Depressivity
Time frame: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
The anhedonic depression scale of the Mood and Anxiety Symptom Questionnaire (MASQ; Clark \& Watson, 1991) was used to measure anhedonic depressivity. Participants rated items of the MASQ (Clark \& Watson, 1991) on a scale from 1-5 (1 = Not at All; 5 = Extremely) based on how they felt over the past week. The anhedonic depression subscale includes 22 items (e.g., "Felt like there wasn't anything interesting or fun to do"). A mean score was calculated, with higher scores indicating more anhedonic depressivity.
9 secondary outcomes
Positive Affect
Time frame: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Willingness to Sacrifice
Time frame: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Other-Inclusive Self Concept
Time frame: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Interaction Quality
Time frame: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Anxious Arousal
Time frame: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Negative Affect
Time frame: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Emotional Closeness
Time frame: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Desired Emotional Closeness
Time frame: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Worry
Time frame: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 May 2026.
- BackgroundFlores Jr, L. E., & Berenbaum, H. (2014). Desired emotional closeness moderates the prospective relations between levels of perceived emotional closeness and psychological distress. Journal of Social and Clinical Psychology, 33(8), 673-700. https://doi.org/10.1521/jscp.2014.33.8.673
- BackgroundFlores Jr, L. E., & Berenbaum, H. (2012). Desire for emotional closeness moderates the effectiveness of the social regulation of emotion. Personality and Individual Differences, 53(8), 952-957. https://doi.org/10.1016/j.paid.2012.07.009
- Background: PubMed 2076086Meyer TJ, Miller ML, Metzger RL, Borkovec TD. Development and validation of the Penn State Worry Questionnaire. Behav Res Ther. 1990;28(6):487-95. doi: 10.1016/0005-7967(90)90135-6.
- BackgroundHayes, A. F. (2018). Introduction to mediation, moderation, and conditional process analysis: A regression-based approach (2nd ed.) Guilford publications.
- BackgroundHayes, A. F. (2012). PROCESS: A versatile computational tool for observed variable mediation, moderation, and conditional process modeling [White paper]. Retrieved from http://www.afhayes.com/public/process2012.pdf
- Background: PubMed 27917136Trautwein FM, Naranjo JR, Schmidt S. Decentering the Self? Reduced Bias in Self- vs. Other-Related Processing in Long-Term Practitioners of Loving-Kindness Meditation. Front Psychol. 2016 Nov 21;7:1785. doi: 10.3389/fpsyg.2016.01785. eCollection 2016.
- BackgroundBierhoff, H. W., Grau, I., & Ludwig, A. (1993). Marburger Einstellungsinventar zu Liebesstilen (MEIL). Hogrefe.
- BackgroundWheeler, L., & Reis, H. T., (1991). Self-recording of everyday life events: Origins, types, and uses. Journal of Personality, 59, 339-354. doi:10.1111/j.1467-6494.1991.tb00252.x
- BackgroundAron, A., Aron, E. N., & Smollan, D. (1992). Inclusion of the other in the self scale and the structure of interpersonal closeness. Journal of Personality and Social Psychology, 63(4), 596-612. https://doi.org/10.1037/0022-3514.63.4.596
- BackgroundSeppala, E.M., Hutcherson, C.A., Nguyen, D.T., Hutcheson, C. A., & Gross, J. J. (2014). Loving-kindness meditation: A tool to improve healthcare provider compassion, resilience, and patient care. Journal of Compassionate Health Care, 1(1), 1-9. https://doi.org/10.1186/s40639-014-0005-9
- Background: PubMed 26068873Gachter S, Starmer C, Tufano F. Measuring the Closeness of Relationships: A Comprehensive Evaluation of the 'Inclusion of the Other in the Self' Scale. PLoS One. 2015 Jun 12;10(6):e0129478. doi: 10.1371/journal.pone.0129478. eCollection 2015.
- Background: PubMed 3397865Watson D, Clark LA, Tellegen A. Development and validation of brief measures of positive and negative affect: the PANAS scales. J Pers Soc Psychol. 1988 Jun;54(6):1063-70. doi: 10.1037//0022-3514.54.6.1063.
- Individual participant dataSharing planned: Yes. Deidentified participant data will be shared on Open Science Framework. Only IPD used in the results publication will be shared.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Luis Flores, Ph.D. principal investigator
Queen's University and Rutgers University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Loving-Kindness Meditation and Visualization in people with Depression and Anxiety Symptoms, run by Luis Flores at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 28 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Anhedonic Depressivity (time frame: Assessed once at baseline (Day 0) and once at follow-up after the intervention (follow up sent on Day 8).). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07611253, which also lists 13 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 May 2026.