Schizophrenia Spectrum DisordersSOLLUSIONSNCT07602712
Using Illusions to Boost Social Cognition
A study testing Visual-illusion social cognition session (immediate) and Visual-illusion social cognition session (delayed) in people with Schizophrenia Spectrum Disorders and Social Cognition, run by Hôpital le Vinatier at 1 site in France.
Trial summary
This study aims to explore whether the observation of complex visual objects can help improve social cognition in people living with psychotic disorders. Social cognition refers to the ability to understand what others think, feel, or intend, and plays a key role in social relationships and daily interactions. Read more about this study
- Who is it for?
- Ages 18 to 40 years
- Conditions the study is for
- Schizophrenia Spectrum Disorders, Social Cognition
- What is being tested?
- Visual-illusion social cognition session (immediate) and Visual-illusion social cognition session (delayed)
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteFrance
- Study dates
- Jul 2026to Feb 2029
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Aged 18 to 40 years
- Fluent French speaker
- Has provided written informed consent
- For individuals under guardianship (curatorship): inclusion is permitted if the curator is available to assist or advise when needed.
- Established diagnosis of schizophrenia, schizoaffective disorder, schizophreniform disorder, or brief psychotic disorder according to theDiagnostic and statistical manual of mental disorders (DSM-5-TR) criteria
- Presence of social cognition impairment, defined by:subjective complaint reported by the participant or identified by care teams regarding difficulties in social interaction and clinical confirmation of observable difficulties (e.g., social withdrawal, misinterpretation of others' intentions, inappropriate social behaviour)
- Membership or entitlement to a social security plan
Who cannot join
- Clinical state incompatible with participation in group-based activities (e.g., severe psychomotor agitation, severe behavioural disturbance)
- Concurrent participation in another social cognition remediation program
- Diagnosis of intellectual disability
- Insufficient comprehension of French for verbal interaction and test completion
- Significant change in psychotropic medication within the past month
- Uncorrectable visual impairment preventing participation
- Pregnant women
- Individuals under full guardianship (tutorship)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Méline Devaluez, PhD contact
About this study
Official title: Socio-cognitive Benefits of Exposure to Visual Illusions in Patients With Psychotic Disorders
This study aims to explore whether the observation of complex visual objects can help improve social cognition in people living with psychotic disorders. Social cognition refers to the ability to understand what others think, feel, or intend, and plays a key role in social relationships and daily interactions.
Main questions this study aims to answer:
- Does dyadic exposure to complex visual objects improve mental state attribution, as measured by the Faux Pas Test?
- Does the intervention enhance related domains of social cognition, including implicit intention inference (Hinting Task), interpretation of complex interactions (Movie for the Assessment of Social Cognition, MASC), and reduction of hostile attribution biases (Ambiguous Intentions Hostility Questionnaire, AIHQ)?
- Are improvements maintained after one month, and do patients who receive the intervention later (waitlist group) show the same benefits once exposed?
Read the detailed description
This study is a randomized, controlled, monocentric trial evaluating a novel sensory-motor rehabilitation approach for social cognition. The study is based on the hypothesis that perception is interpretative and viewpoint-dependent, and that realizing this through concrete experience could generalize to higher-level cognitive processes required for social understanding.
Participants will attend three visits and complete questionnaires and tasks that assess social understanding before and after the activity, and again one month later.
Two groups will take part: one completing the workshop shortly after inclusion, and one completing it after a delay, allowing comparison over time. Participants will be randomized in one condition.
This research does not involve medication. It consists of simple tasks such as observing and describing visual stimuli, followed by a facilitated discussion.
Neuropsychological tests and questionnaires will be used to measure changes over time.
Expected impact: By inducing concrete perspective-shifts, the intervention aims to improve mentalizing, reduce egocentric biases, and strengthen interpretation of social cues. This bottom-up sensory-motor approach may overcome limitations of classical cognitive remediation programs by promoting deep experiential learning rather than top-down instruction.
If effective, the method may support long-term social reintegration, psychosocial functioning, and inspire wider clinical applications due to its low cost, ease of deployment, and strong ecological engagement.
- Conditions
- Schizophrenia Spectrum Disorders, Social Cognition
- Being tested
- Visual-illusion social cognition session (immediate), Visual-illusion social cognition session (delayed)
- Keywords
- Schizophrenia, Psychosis, Social Cognition, Mentalizing, Theory of Mind, Cognitive Remediation, Metacognition, Perspective-Taking, Visual Illusions, Viewpoint Illusions, Bottom-Up Intervention, Sensorimotor Rehabilitation, Faux Pas Test, Hinting Task, Social Interaction, Rehabilitation in Psychosis
- Medical subject headings
- Schizophrenia, Psychotic Disorders, Illusions
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Visual-illusion social cognition session (immediate)Behavioural
A guided session of approximately 45 minutes. The core rehabilitation tool consists of multiple-perspective illusion boxes. Each participant stands on one side of the box and perceives a different shape than their partner. The session unfolds in 3 structured phases:
- For each illusion : Participants observe objects silently and draw what they see.
- Perspective confrontation + Card selection: Drawings and interpretation cards are exchanged and discussed.
- Perspective switching : Participants swap positions to reveal the alternative visual interpretation.
The session is followed by a short structured discussion with a psychologist focused on perspective-taking and interpretation of social cues.
Visual-illusion social cognition session (delayed)Behavioural
A guided session of approximately 45 minutes. The core rehabilitation tool consists of multiple-perspective illusion boxes. Each participant stands on one side of the box and perceives a different shape than their partner. The session unfolds in 3 structured phases: 1. For each illusion : Participants observe objects silently and draw what they see. 2. Perspective confrontation + Card selection: Drawings and interpretation cards are exchanged and discussed. 3. Perspective switching : Participants swap positions to reveal the alternative visual interpretation. The session is followed by a short structured discussion with a psychologist focused on perspective-taking and interpretation of social cues. Delivered after a delay following baseline assessment.
| Study group | Role | What they receive |
|---|---|---|
| Immediate intervention | Experimental | Participants receive the visual-perception session shortly after baseline assessment. They complete neurocognitive and social cognition tests before exposure, immediately after, and again at one-month follow-up. Receives: Behavioral: Visual-illusion social cognition session (immediate) |
| Delayed Intervention (Wait-list Control) | Active comparator | Participants complete the same assessments as Arm 1 but receive the intervention only after a waiting period. This arm allows comparison between natural progression and workshop effects prior to exposure. Receives: Behavioral: Visual-illusion social cognition session (delayed) |
What is being measured
The primary outcome is the main question the study is designed to answer.
"Faux Pas" test total score
- Total of correctly recognised "Faux Pas" Score range : 0 - 30 Minimum (0) : no correct detection of faux pas Maximum (30) : all faux pas correctly detected
- Total of identified absence of "Faux Pas" Score range : 0 - 10 Minimum (0) : incorrectly identifies absence of faux pas Maximum (10) : correctly identifies absence of faux pas
- Total score of control question comprehension Score range : 0 - 20 Minimum (0) : poor comprehension Maximum (20) : Full comprehension
Measured: Change from pre to post intervention (up to 3 hours)
Secondary outcomes (2)
Hinting Task
- Number of correctly inferred items with hint 1 Score range : 0 - 20 Minimum (0) : No correct inference of intentions Maximum (20) : All intentions correctly inferred
- Number of correctly inferred items with hint 2 Score range : 0 - 20 Minimum (0) : No correct inference of intentions Maximum (20) : All intentions correctly inferred
Measured: Change from pre to post intervention (up to 3 hours)
MASC performance
Number of correct responses Score range 0 - 45 Minimum (0) : No correct mental state inference Maximum (45) : All mental states correctly inferred
Measured: Change from pre intervention to follow-up session (up to a month and a half)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 May 2026
- Study startJul 2026 (estimated)
- Primary completionJan 2029 (estimated)
- Study completionFeb 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Schizophrenia Spectrum DisordersStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Two groups will take part: one completing the workshop shortly after inclusion, and one completing it after a delay, allowing comparison over time.
- Masking
- None (open label)
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Hôpital le Vinatier
- Sponsor type
- University, hospital or other
- Collaborators
- INSERM 1028
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07602712
- Sponsor's protocol ID
- 2025-A02057-42
- Acronym
- SOLLUSIONS
- Status last verified
- May 2026
- First submitted
- 12 May 2026
- Last updated
- 22 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Anonymized IPD that underlie results in a publication may be shared upon reasonable scientific request following publication of study results.
Study at a glance
From the registry record, last updated by the sponsor on 22 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Socio-cognitive Benefits of Exposure to Visual Illusions in Patients With Psychotic Disorders
- ClinicalTrials.gov ID
- NCT07602712
- Acronym / sponsor ID
- SOLLUSIONS / 2025-A02057-42
- Conditions
- Schizophrenia Spectrum Disorders, Social Cognition
- Keywords
- Schizophrenia, Psychosis, Social Cognition, Mentalizing, Theory of Mind, Cognitive Remediation, Metacognition, Perspective-Taking
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Hôpital le VinatierUniversity, hospital or other
- Collaborators
- INSERM 1028
- Study start
- Jul 2026 (estimated)
- Primary completion
- Jan 2029 (estimated)
- Study completion
- Feb 2029 (estimated)
- First posted
- 22 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to explore whether the observation of complex visual objects can help improve social cognition in people living with psychotic disorders. Social cognition refers to the ability to understand what others think, feel, or intend, and plays a key role in social relationships and daily interactions.
Main questions this study aims to answer:
- Does dyadic exposure to complex visual objects improve mental state attribution, as measured by the Faux Pas Test?
- Does the intervention enhance related domains of social cognition, including implicit intention inference (Hinting Task), interpretation of complex interactions (Movie for the Assessment of Social Cognition, MASC), and reduction of hostile attribution biases (Ambiguous Intentions Hostility Questionnaire, AIHQ)?
- Are improvements maintained after one month, and do patients who receive the intervention later (waitlist group) show the same benefits once exposed?
Detailed description
This study is a randomized, controlled, monocentric trial evaluating a novel sensory-motor rehabilitation approach for social cognition. The study is based on the hypothesis that perception is interpretative and viewpoint-dependent, and that realizing this through concrete experience could generalize to higher-level cognitive processes required for social understanding.
Participants will attend three visits and complete questionnaires and tasks that assess social understanding before and after the activity, and again one month later.
Two groups will take part: one completing the workshop shortly after inclusion, and one completing it after a delay, allowing comparison over time. Participants will be randomized in one condition.
This research does not involve medication. It consists of simple tasks such as observing and describing visual stimuli, followed by a facilitated discussion.
Neuropsychological tests and questionnaires will be used to measure changes over time.
Expected impact: By inducing concrete perspective-shifts, the intervention aims to improve mentalizing, reduce egocentric biases, and strengthen interpretation of social cues. This bottom-up sensory-motor approach may overcome limitations of classical cognitive remediation programs by promoting deep experiential learning rather than top-down instruction.
If effective, the method may support long-term social reintegration, psychosocial functioning, and inspire wider clinical applications due to its low cost, ease of deployment, and strong ecological engagement.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Two groups will take part: one completing the workshop shortly after inclusion, and one completing it after a delay, allowing comparison over time.
| Arm | Type | Receives |
|---|---|---|
| Immediate intervention | Experimental | Behavioral: Visual-illusion social cognition session (immediate)Participants receive the visual-perception session shortly after baseline assessment. They complete neurocognitive and social cognition tests before exposure, immediately after, and again at one-month follow-up. |
| Delayed Intervention (Wait-list Control) | Active comparator | Behavioral: Visual-illusion social cognition session (delayed)Participants complete the same assessments as Arm 1 but receive the intervention only after a waiting period. This arm allows comparison between natural progression and workshop effects prior to exposure. |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- Aged 18 to 40 years
- Fluent French speaker
- Has provided written informed consent
- For individuals under guardianship (curatorship): inclusion is permitted if the curator is available to assist or advise when needed.
- Established diagnosis of schizophrenia, schizoaffective disorder, schizophreniform disorder, or brief psychotic disorder according to theDiagnostic and statistical manual of mental disorders (DSM-5-TR) criteria
Key exclusion criteria (8 listed)
- Clinical state incompatible with participation in group-based activities (e.g., severe psychomotor agitation, severe behavioural disturbance)
- Concurrent participation in another social cognition remediation program
- Diagnosis of intellectual disability
- Insufficient comprehension of French for verbal interaction and test completion
- Significant change in psychotropic medication within the past month
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Visual-illusion social cognition session (immediate)A guided session of approximately 45 minutes. The core rehabilitation tool consists of multiple-perspective illusion boxes. Each participant stands on one side of the box and perceives a different shape than their partner. The session unfolds in 3 structured phases: 1. For each illusion : Participants observe objects silently and draw what they see. 2. Perspective confrontation + Card selection: Drawings and interpretation cards are exchanged and discussed. 3. Perspective switching : Participants swap positions to reveal the alternative visual interpretation. The session is followed by a short structured discussion with a psychologist focused on perspective-taking and interpretation of social cues. | Behavioural | Immediate intervention |
| Visual-illusion social cognition session (delayed)A guided session of approximately 45 minutes. The core rehabilitation tool consists of multiple-perspective illusion boxes. Each participant stands on one side of the box and perceives a different shape than their partner. The session unfolds in 3 structured phases: 1. For each illusion : Participants observe objects silently and draw what they see. 2. Perspective confrontation + Card selection: Drawings and interpretation cards are exchanged and discussed. 3. Perspective switching : Participants swap positions to reveal the alternative visual interpretation. The session is followed by a short structured discussion with a psychologist focused on perspective-taking and interpretation of social cues. Delivered after a delay following baseline assessment. | Behavioural | Delayed Intervention (Wait-list Control) |
Primary outcome
"Faux Pas" test total score
Time frame: Change from pre to post intervention (up to 3 hours)
1. Total of correctly recognised "Faux Pas" Score range : 0 - 30 Minimum (0) : no correct detection of faux pas Maximum (30) : all faux pas correctly detected 2. Total of identified absence of "Faux Pas" Score range : 0 - 10 Minimum (0) : incorrectly identifies absence of faux pas Maximum (10) : correctly identifies absence of faux pas 3. Total score of control question comprehension Score range : 0 - 20 Minimum (0) : poor comprehension Maximum (20) : Full comprehension
2 secondary outcomes
Hinting Task
Time frame: Change from pre to post intervention (up to 3 hours)
MASC performance
Time frame: Change from pre intervention to follow-up session (up to a month and a half)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 May 2026.
- Individual participant dataSharing planned: Yes. Anonymized IPD that underlie results in a publication may be shared upon reasonable scientific request following publication of study results.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Méline Devaluez, PhD contact
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Visual-illusion social cognition session (immediate) and Visual-illusion social cognition session (delayed) in people with Schizophrenia Spectrum Disorders and Social Cognition, run by Hôpital le Vinatier at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 22 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Joy El KHOURY (+330437915534, joy.el-khoury@inserm.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
"Faux Pas" test total score (time frame: Change from pre to post intervention (up to 3 hours)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 May 2026.