Idiopathic Adolescent ScoliosisCSE RAB ISNCT07601893
Effects of Core Stabilization Exercises and Rotation Angular Breathing Exercises Among Idiopathic Scoliosis Patients
A study testing Core Stabilization Exercises in people with Idiopathic Adolescent Scoliosis and Scoliosis Idiopathic, run by Lahore University of Biological and Applied Sciences at 2 sites in Pakistan.
Trial summary
This study is a single-blind, two-arm parallel-group randomized controlled trial designed to evaluate the effects of core stabilization exercises combined with rotational angular breathing exercises on adolescents with idiopathic scoliosis. Read more about this study
- Who is it for?
- Ages 10 to 17 years
- Conditions the study is for
- Idiopathic Adolescent Scoliosis, Scoliosis Idiopathic
- What is being tested?
- Core Stabilization Exercises
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- 2 sitesPakistan
- Study dates
- 18 Jun 2026to 15 Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 to 17 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Adolescents aged 10-17 years
- Both male and female participants
- Diagnosed cases of idiopathic scoliosis
- Cobb's angle between 10° and 25°
- Both thoracic and lumbar spine scoliosis patients
- Both C-shaped or S-shaped curve scoliosis patients
Who cannot join
- Previous spinal surgery
- Significant neuromuscular disorders (e.g, muscular dystrophy, cerebral palsy)
- Other medical conditions affecting participation (e.g, respiratory or cardiac)
- Any contraindication to exercise program
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan2 sites
General hospital lahore
Lahore, Punjab Province, 5400
Dr. Ijaz Ahmad Burq, PhD PT, +92 334615892, burq802@yahoo.com
Ghurki trust and teaching hospital lahore
Lahore, Punjab Province, 5400
Prof. Hafiz Muhammad Asim, PhD, +92 3009400346, info@hafizasim.com
About this study
Official title: Effects of Core Stabilization Exercises and Rotational Angular Breathing Exercises on Cobb's Angle, Trunk Rotation, Inspiratory Capacity and Spinal Appearance Among Idopathic Scoliosis Patients
This study is a single-blind, two-arm parallel-group randomized controlled trial designed to evaluate the effects of core stabilization exercises combined with rotational angular breathing exercises on adolescents with idiopathic scoliosis. Participants aged 10-18 years with a Cobb angle between 10° and 25° will be randomly assigned to either an experimental group receiving a structured exercise program or a control group receiving standard care.
The intervention will be conducted over 12 weeks, with outcomes assessed at baseline, post-intervention, and follow-up periods. Primary outcomes include Cobb angle, angle of trunk rotation, inspiratory capacity, and spinal appearance. The study aims to determine whether the combined exercise approach is more effective than standard care in improving spinal alignment, respiratory function, and physical appearance.
Read the detailed description
Adolescent idiopathic scoliosis is a three-dimensional spinal deformity characterized by lateral curvature and vertebral rotation, commonly developing during adolescence. It is associated with postural asymmetry, trunk deformity, reduced pulmonary function, and decreased quality of life. Conservative management strategies, particularly exercise-based interventions, are widely used to prevent progression and improve functional outcomes.
Core stabilization exercises focus on strengthening the muscles surrounding the spine, including abdominal, paraspinal, and pelvic muscles. These exercises enhance spinal stability, improve postural control, and reduce compensatory movement patterns. However, core stabilization alone may not fully address thoracic asymmetry and respiratory limitations associated with scoliosis.
Rotational angular breathing exercises are scoliosis-specific techniques aimed at improving thoracic expansion, promoting spinal de-rotation, and enhancing pulmonary function. These exercises involve controlled breathing patterns that target the concave side of the rib cage, facilitating improved ventilation and postural correction.
Although both interventions have shown individual effectiveness, limited evidence exists regarding their combined effects on structural, functional, and patient-reported outcomes in adolescents with idiopathic scoliosis. Therefore, this study aims to evaluate the combined impact of core stabilization and rotational angular breathing exercises on multiple clinical outcomes.
This study will be conducted as a single-blind, randomized controlled trial with two parallel groups. A total of 32 participants meeting eligibility criteria will be recruited and randomly assigned in a 1:1 ratio to either the experimental group or the control group.
Participants in the experimental group will undergo a supervised exercise program consisting of core stabilization exercises (planks, bridges, bird dog, and dead bug) combined with rotational angular breathing exercises. The program will be performed 3-4 times per week for 12 weeks, with gradual progression in intensity and duration. The control group will receive standard care without a structured exercise program.
Outcome measures will be assessed at baseline, immediately after the 12-week intervention, and at 3-month and 6-month follow-up periods. Primary outcomes include Cobb angle measured via radiographs, angle of trunk rotation assessed using a scoliometer, inspiratory capacity measured using spirometry, and spinal appearance evaluated using the Spinal Appearance Questionnaire. Secondary outcomes include quality of life assessed using the Scoliosis Research Society-22 questionnaire.
Blinding will be applied at the level of outcome assessors to reduce measurement bias. Statistical analysis will be conducted to compare within-group and between-group differences over time.
The results of this study are expected to provide evidence on the effectiveness of a combined exercise approach targeting both biomechanical and respiratory components of scoliosis. This may support the development of comprehensive rehabilitation protocols for adolescents with idiopathic scoliosis.
- Being tested
- Core Stabilization Exercises, Standard Care (in control arm)
- Keywords
- Core stabilization exercises, Rotational Angular Breathing Exercises, Cobb's angle, Inspiratory capacity, Idiopathic scoliosis, Spinal Appearance, Trunk rotation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Core Stabilization ExercisesOther
Core stabilization exercises: planks, bridges, bird dog, and dead bug Rotational angular breathing exercises: emphasizing thoracic expansion, asymmetric rib cage mobility, and postural correction through controlled inhalation and prolonged exhalation All exercises will be performed under supervised conditions initially, with emphasis on neuromuscular control, spinal stability, and coordinated breathing.
Each session will last 40 minutes, including:
3 sessions per week 12-week intervention period 5 minutes warm-up 25 minutes core stabilization exercises 10 minutes rotational angular breathing exercises
- Cool-down and postural awareness exercises
Standard Care (in control arm)Other
Participants in the control group will receive conventional physiotherapy management routinely used for idiopathic scoliosis. The intervention will focus on posture correction, spinal mobility, flexibility, general strengthening, and breathing awareness exercises without specialized core stabilization or rotational angular breathing techniques.
The program will include:
Warm-up exercises Stretching exercises for trunk and lower limb muscles Spinal mobility exercises Basic abdominal and back strengthening exercises Postural correction and ergonomic education Diaphragmatic breathing and relaxation exercises Cool-down exercises
Sessions will be supervised initially by a physiotherapist to ensure correct technique and safety.
Frequency and Duration 3 sessions per week 12-week intervention period 40 minutes per session
Session Structure 5 minutes warm-up 25 minutes conventional physiotherapy exercises 5 minutes breathing exercises 5 minutes cool-down and posture education
| Study group | Role | What they receive |
|---|---|---|
| Core stabilization and rotational angular breathing exercises | Experimental | Planks involve maintaining a straight body position from head to heels while resting on the forearms and toes, effectively strengthening the abdominal muscles and lower back. Bridges require participants to lie on their backs with knees bent and feet flat, lifting their hips to create a straight line from shoulders to knees, targeting the glutes and hamstrings for enhanced pelvic stability. The bird dog exercise is performed on hands and knees, where participants extend one arm and the opposite leg, promoting balance and coordination while engaging the core. Lastly, dead bugs involve lying on the back with arms and legs raised, lowering one arm and the opposite leg while keeping the lower back pressed into the floor, which effectively engages deep core muscles. Additionally, the program will incorporate rotational angular breathing exercises, focusing on enhancing thoracic expansion and postural control through specific breathing techniques. Receives: Other: Core Stabilization Exercises |
| Standard care | Active comparator | Participants in the active comparator group will receive conventional physiotherapy routinely provided for individuals with idiopathic scoliosis. The program will focus on general posture correction, flexibility, spinal mobility, and basic strengthening exercises without specialized core stabilization or rotational angular breathing techniques.
Standard Care Intervention:
General stretching exercises for trunk and lower limb muscles Active range of motion exercises for spinal mobility Conventional postural correction exercises Basic strengthening exercises for back and abdominal muscles Breathing awareness exercises without rotational angular emphasis Education regarding posture maintenance and ergonomic advice Frequency: 3 sessions per week Total Duration: 12 weeks Session Duration: 40 minutes Session Structure 5 minutes warm-up 25 minutes conventional physiotherapy exercises 5 minutes breathing and relaxation exercises 5 minutes cool-down and posture education Receives: Other: Standard Care (in control arm) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cobb's angle
Cobb angle is a radiographic measure used to quantify the degree of spinal curvature in scoliosis. It is measured by identifying the most tilted vertebrae at the upper and lower ends of the curve on an anteroposterior spinal radiograph and calculating the angle between intersecting perpendicular lines drawn from these vertebrae.
Time Frame: Baseline, 4 weeks, 8 weeks and 12 weeks
Measured: 12 Weeks
Trunk rotation
Angle of Trunk Rotation is assessed using a scoliometer during the Adam's Forward Bend Test. The device is placed over the spine at the point of maximum deformity to quantify axial trunk rotation and rib hump prominence.
Time Frame: Baseline, 4 weeks, 8 weeks and 12 weeks
Measured: 12 weeks
Inspiratory capacity
Inspiratory capacity is defined as the maximum volume of air that can be inhaled after a normal expiration. It is measured using spirometry with a calibrated spirometer to assess pulmonary function and thoracic expansion.
Time Frame: Baseline, 4 weeks, 8 weeks and 12 weeks
Measured: 12 weeks
Spinal appearance
The Spinal Appearance Questionnaire is a patient-reported outcome measure that evaluates the perception of spinal deformity and cosmetic appearance. It includes domains related to trunk asymmetry, curve perception, and self-image.
Time Frame: Baseline, 4 weeks, 8 weeks and 12 weeks
Measured: 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 May 2026
- Study start18 Jun 2026 (estimated)
- Primary completion15 Oct 2026 (estimated)
- Study completion15 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Idiopathic Adolescent ScoliosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- This study is a randomized controlled interventional trial designed to evaluate the effects of core stabilization exercises combined with rotational angular breathing exercises on Cobb's angle, trunk rotation, inspiratory capacity, and spinal appearance among patients with idiopathic scoliosis. Eligible participants will be randomly allocated into two parallel groups using a simple randomization method. The experimental group will receive a structured exercise program consisting of core stabilization exercises and rotational angular breathing exercises in addition to conventional physiotherapy care. The control group will receive standard conventional physiotherapy management only. Both groups will undergo supervised treatment sessions three times per week for 12 weeks, with each session lasting approximately 40 minutes. Outcome measures will be assessed at baseline and after completion of the intervention period to compare the effectiveness of the interventions between groups.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 32 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Lahore University of Biological and Applied Sciences
- Sponsor type
- University, hospital or other
- Collaborators
- Ghurki Trust and Teaching Hospital
- Responsible party
- Principal investigator, Umber Nawaz, Lahore University of Biological and Applied Sciences
- Investigators
- Prof. Shoaib Waqas, Phd, Study chair, Lahore University of Biological and Applied Sciences
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07601893
- Sponsor's protocol ID
- UBAS/ERB/26/04/035
- Other IDs
- U1111-1339-6644
- Acronym
- CSE RAB IS
- Status last verified
- Apr 2026
- First submitted
- 15 May 2026
- Last updated
- 18 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: I commit to not sharing any data obtained during the study until its publication, ensuring confidentiality throughout the research process. Following the study, all collected data will be retained for a period of two years to allow for necessary analysis and validation. After this retention period, all data will be permanently deleted to comply with data protection regulations and to safeguard the privacy of all participants involved.
Study at a glance
From the registry record, last updated by the sponsor on 18 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Core Stabilization Exercises and Rotational Angular Breathing Exercises on Cobb's Angle, Trunk Rotation, Inspiratory Capacity and Spinal Appearance Among Idopathic Scoliosis Patients
- ClinicalTrials.gov ID
- NCT07601893
- Acronym / sponsor ID
- CSE RAB IS / UBAS/ERB/26/04/035
- Keywords
- Core stabilization exercises, Rotational Angular Breathing Exercises, Cobb's angle, Inspiratory capacity, Idiopathic scoliosis, Spinal Appearance, Trunk rotation
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 32 participants (estimated)
- Lead sponsor
- Lahore University of Biological and Applied SciencesUniversity, hospital or other
- Collaborators
- Ghurki Trust and Teaching Hospital
- Study start
- 18 Jun 2026 (estimated)
- Primary completion
- 15 Oct 2026 (estimated)
- Study completion
- 15 Nov 2026 (estimated)
- First posted
- 22 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is a single-blind, two-arm parallel-group randomized controlled trial designed to evaluate the effects of core stabilization exercises combined with rotational angular breathing exercises on adolescents with idiopathic scoliosis. Participants aged 10-18 years with a Cobb angle between 10° and 25° will be randomly assigned to either an experimental group receiving a structured exercise program or a control group receiving standard care.
The intervention will be conducted over 12 weeks, with outcomes assessed at baseline, post-intervention, and follow-up periods. Primary outcomes include Cobb angle, angle of trunk rotation, inspiratory capacity, and spinal appearance. The study aims to determine whether the combined exercise approach is more effective than standard care in improving spinal alignment, respiratory function, and physical appearance.
Detailed description
Adolescent idiopathic scoliosis is a three-dimensional spinal deformity characterized by lateral curvature and vertebral rotation, commonly developing during adolescence. It is associated with postural asymmetry, trunk deformity, reduced pulmonary function, and decreased quality of life. Conservative management strategies, particularly exercise-based interventions, are widely used to prevent progression and improve functional outcomes.
Core stabilization exercises focus on strengthening the muscles surrounding the spine, including abdominal, paraspinal, and pelvic muscles. These exercises enhance spinal stability, improve postural control, and reduce compensatory movement patterns. However, core stabilization alone may not fully address thoracic asymmetry and respiratory limitations associated with scoliosis.
Rotational angular breathing exercises are scoliosis-specific techniques aimed at improving thoracic expansion, promoting spinal de-rotation, and enhancing pulmonary function. These exercises involve controlled breathing patterns that target the concave side of the rib cage, facilitating improved ventilation and postural correction.
Although both interventions have shown individual effectiveness, limited evidence exists regarding their combined effects on structural, functional, and patient-reported outcomes in adolescents with idiopathic scoliosis. Therefore, this study aims to evaluate the combined impact of core stabilization and rotational angular breathing exercises on multiple clinical outcomes.
This study will be conducted as a single-blind, randomized controlled trial with two parallel groups. A total of 32 participants meeting eligibility criteria will be recruited and randomly assigned in a 1:1 ratio to either the experimental group or the control group.
Participants in the experimental group will undergo a supervised exercise program consisting of core stabilization exercises (planks, bridges, bird dog, and dead bug) combined with rotational angular breathing exercises. The program will be performed 3-4 times per week for 12 weeks, with gradual progression in intensity and duration. The control group will receive standard care without a structured exercise program.
Outcome measures will be assessed at baseline, immediately after the 12-week intervention, and at 3-month and 6-month follow-up periods. Primary outcomes include Cobb angle measured via radiographs, angle of trunk rotation assessed using a scoliometer, inspiratory capacity measured using spirometry, and spinal appearance evaluated using the Spinal Appearance Questionnaire. Secondary outcomes include quality of life assessed using the Scoliosis Research Society-22 questionnaire.
Blinding will be applied at the level of outcome assessors to reduce measurement bias. Statistical analysis will be conducted to compare within-group and between-group differences over time.
The results of this study are expected to provide evidence on the effectiveness of a combined exercise approach targeting both biomechanical and respiratory components of scoliosis. This may support the development of comprehensive rehabilitation protocols for adolescents with idiopathic scoliosis.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- This study is a randomized controlled interventional trial designed to evaluate the effects of core stabilization exercises combined with rotational angular breathing exercises on Cobb's angle, trunk rotation, inspiratory capacity, and spinal appearance among patients with idiopathic scoliosis. Eligible participants will be randomly allocated into two parallel groups using a simple randomization method. The experimental group will receive a structured exercise program consisting of core stabilization exercises and rotational angular breathing exercises in addition to conventional physiotherapy care. The control group will receive standard conventional physiotherapy management only. Both groups will undergo supervised treatment sessions three times per week for 12 weeks, with each session lasting approximately 40 minutes. Outcome measures will be assessed at baseline and after completion of the intervention period to compare the effectiveness of the interventions between groups.
| Arm | Type | Receives |
|---|---|---|
| Core stabilization and rotational angular breathing exercises | Experimental | Other: Core Stabilization ExercisesPlanks involve maintaining a straight body position from head to heels while resting on the forearms and toes, effectively strengthening the abdominal muscles and lower back. Bridges require participants to lie on their backs with knees bent and feet flat, lifting their hips to create a straight line from shoulders to knees, targeting the glutes and hamstrings for enhanced pelvic stability. The bird dog exercise is performed on hands and knees, where participants extend one arm and the opposite leg, promoting balance and coordination while engaging the core. Lastly, dead bugs involve lying on the back with arms and legs raised, lowering one arm and the opposite leg while keeping the lower back pressed into the floor, which effectively engages deep core muscles. Additionally, the program will incorporate rotational angular breathing exercises, focusing on enhancing thoracic expansion and postural control through specific breathing techniques. |
| Standard care | Active comparator | Other: Standard Care (in control arm)Participants in the active comparator group will receive conventional physiotherapy routinely provided for individuals with idiopathic scoliosis. The program will focus on general posture correction, flexibility, spinal mobility, and basic strengthening exercises without specialized core stabilization or rotational angular breathing techniques. Standard Care Intervention: General stretching exercises for trunk and lower limb muscles Active range of motion exercises for spinal mobility Conventional postural correction exercises Basic strengthening exercises for back and abdominal muscles Breathing awareness exercises without rotational angular emphasis Education regarding posture maintenance and ergonomic advice Frequency: 3 sessions per week Total Duration: 12 weeks Session Duration: 40 minutes Session Structure 5 minutes warm-up 25 minutes conventional physiotherapy exercises 5 minutes breathing and relaxation exercises 5 minutes cool-down and posture education |
Who may qualify
- Ages
- 10 to 17 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (6 listed)
- Adolescents aged 10-17 years
- Both male and female participants
- Diagnosed cases of idiopathic scoliosis
- Cobb's angle between 10° and 25°
- Both thoracic and lumbar spine scoliosis patients
Key exclusion criteria (4 listed)
- Previous spinal surgery
- Significant neuromuscular disorders (e.g, muscular dystrophy, cerebral palsy)
- Other medical conditions affecting participation (e.g, respiratory or cardiac)
- Any contraindication to exercise program
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Core Stabilization ExercisesCore stabilization exercises: planks, bridges, bird dog, and dead bug Rotational angular breathing exercises: emphasizing thoracic expansion, asymmetric rib cage mobility, and postural correction through controlled inhalation and prolonged exhalation All exercises will be performed under supervised conditions initially, with emphasis on neuromuscular control, spinal stability, and coordinated breathing. Each session will last 40 minutes, including: 3 sessions per week 12-week intervention period 5 minutes warm-up 25 minutes core stabilization exercises 10 minutes rotational angular breathing exercises • Cool-down and postural awareness exercises | Other | Core stabilization and rotational angular breathing exercises |
| Standard Care (in control arm)Participants in the control group will receive conventional physiotherapy management routinely used for idiopathic scoliosis. The intervention will focus on posture correction, spinal mobility, flexibility, general strengthening, and breathing awareness exercises without specialized core stabilization or rotational angular breathing techniques. The program will include: Warm-up exercises Stretching exercises for trunk and lower limb muscles Spinal mobility exercises Basic abdominal and back strengthening exercises Postural correction and ergonomic education Diaphragmatic breathing and relaxation exercises Cool-down exercises Sessions will be supervised initially by a physiotherapist to ensure correct technique and safety. Frequency and Duration 3 sessions per week 12-week intervention period 40 minutes per session Session Structure 5 minutes warm-up 25 minutes conventional physiotherapy exercises 5 minutes breathing exercises 5 minutes cool-down and posture education | Other | Standard care |
Primary outcome
Cobb's angle
Time frame: 12 Weeks
Cobb angle is a radiographic measure used to quantify the degree of spinal curvature in scoliosis. It is measured by identifying the most tilted vertebrae at the upper and lower ends of the curve on an anteroposterior spinal radiograph and calculating the angle between intersecting perpendicular lines drawn from these vertebrae. Time Frame: Baseline, 4 weeks, 8 weeks and 12 weeks
Trunk rotation
Time frame: 12 weeks
Angle of Trunk Rotation is assessed using a scoliometer during the Adam's Forward Bend Test. The device is placed over the spine at the point of maximum deformity to quantify axial trunk rotation and rib hump prominence. Time Frame: Baseline, 4 weeks, 8 weeks and 12 weeks
Inspiratory capacity
Time frame: 12 weeks
Inspiratory capacity is defined as the maximum volume of air that can be inhaled after a normal expiration. It is measured using spirometry with a calibrated spirometer to assess pulmonary function and thoracic expansion. Time Frame: Baseline, 4 weeks, 8 weeks and 12 weeks
Spinal appearance
Time frame: 12 weeks
The Spinal Appearance Questionnaire is a patient-reported outcome measure that evaluates the perception of spinal deformity and cosmetic appearance. It includes domains related to trunk asymmetry, curve perception, and self-image. Time Frame: Baseline, 4 weeks, 8 weeks and 12 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Jun 2026.
- Individual participant dataSharing planned: Yes. I commit to not sharing any data obtained during the study until its publication, ensuring confidentiality throughout the research process. Following the study, all collected data will be retained for a period of two years to allow for necessary analysis and validation. After this retention period, all data will be permanently deleted to comply with data protection regulations and to safeguard the privacy of all participants involved.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Prof. Shoaib Waqas, Phd study chair
Lahore University of Biological and Applied Sciences
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Core Stabilization Exercises in people with Idiopathic Adolescent Scoliosis and Scoliosis Idiopathic, run by Lahore University of Biological and Applied Sciences at 2 sites in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 18 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Umber Nawaz, Phd Scholar (+92 3334888279, umber.nawaz@ubas.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cobb's angle (time frame: 12 Weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Jun 2026.