Mental HealthNCT07601477
Assessing the Impact of the Personalized Medicine Clinic on Mental Health Outcomes
An observational study of Mental Health and Depressive Disorder, run by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's.
Trial summary
The aim of this study is to investigate if personalized dosing of antidepressant medications using information gathered at the Personalized Medicine Clinic can improve patients' mental health. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Mental Health, Depressive Disorder, Pharmacogenetic Testing
- What is being tested?
- Personalized Medicine Clinic
- How many people
- 200 participants
- Where
- No sites listed yet
- Study dates
- Jul 2026to Jun 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adult patients referred to the Personalized Medicine clinic for genotype-guided drug dosing and selection related to mental health pharmacotherapy as part of clinical care.
Who may be able to join
- Depressive symptoms
Who cannot join
- Patients who do not speak English
- Patients with severe mental illness including hospitalized patients or patients with suicidal ideation
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
The aim of this study is to investigate if personalized dosing of antidepressant medications using information gathered at the Personalized Medicine Clinic can improve patients' mental health. The main question it aims to answer is if the Personalized Medicine Clinic can improve depressive symptoms based on the CES-D survey score.
- Being tested
- Personalized Medicine Clinic
- Medical subject headings
- Psychological Well-Being, Depressive Disorder
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Personalized Medicine ClinicOther
Personalized Medicine Clinic services with specific focus on pharmacogenetic recommendations and patient education.
| Study group | Role | What they receive |
|---|---|---|
| Personalized Medicine Cohort | Patients referred to the Personalized Medicine Clinic for guidance on antidepressant therapy. Receives: Other: Personalized Medicine Clinic |
What is being measured
The primary outcome is the main question the study is designed to answer.
CES-D Survey Score
CES-D survey score is a 20-item self-reported questionnaire that was designed to assess depressive symptoms. The score is from 0-60 with higher numbers indicating greater depressive symptoms.
Measured: From enrollment to 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 May 2026
- Study startJul 2026 (estimated)
- Primary completionJun 2028 (estimated)
- Study completionJun 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Mental HealthStudies of the same condition, open and under way.
- More trials run by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Richard Kim, London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07601477
- Sponsor's protocol ID
- 128940
- Status last verified
- May 2026
- First submitted
- 15 May 2026
- Last updated
- 26 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Assessing the Impact of the Personalized Medicine Clinic on Mental Health Outcomes
- ClinicalTrials.gov ID
- NCT07601477
- Acronym / sponsor ID
- 128940
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sUniversity, hospital or other
- Study start
- Jul 2026 (estimated)
- Primary completion
- Jun 2028 (estimated)
- Study completion
- Jun 2028 (estimated)
- First posted
- 22 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to investigate if personalized dosing of antidepressant medications using information gathered at the Personalized Medicine Clinic can improve patients' mental health. The main question it aims to answer is if the Personalized Medicine Clinic can improve depressive symptoms based on the CES-D survey score.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Personalized Medicine Cohort | – | Other: Personalized Medicine ClinicPatients referred to the Personalized Medicine Clinic for guidance on antidepressant therapy. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adult patients referred to the Personalized Medicine clinic for genotype-guided drug dosing and selection related to mental health pharmacotherapy as part of clinical care.
Key inclusion criteria (1 listed)
- Depressive symptoms
Key exclusion criteria (2 listed)
- Patients who do not speak English
- Patients with severe mental illness including hospitalized patients or patients with suicidal ideation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Personalized Medicine ClinicPersonalized Medicine Clinic services with specific focus on pharmacogenetic recommendations and patient education. | Other | Personalized Medicine Cohort |
Primary outcome
CES-D Survey Score
Time frame: From enrollment to 6 months
CES-D survey score is a 20-item self-reported questionnaire that was designed to assess depressive symptoms. The score is from 0-60 with higher numbers indicating greater depressive symptoms.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
An observational study of Mental Health and Depressive Disorder, run by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 26 May 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Richard B Kim, MD (519-685-8500 ext. 33553, richard.kim@lhsc.on.ca), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
CES-D Survey Score (time frame: From enrollment to 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 May 2026.