Autism Spectrum Disorder (ASD)NCT07597694
Verbal Intent and Gaze Cues on Action Prediction in ASD
An observational study of Autism Spectrum Disorder (ASD) and Intellectual Disability, run by University of Electronic Science and Technology of China at 1 site in China.
Trial summary
A 2×2×3 mixed design (intent word × object type × group: TD, ASD, ID) was used. Age-matched children watched videos and judged which object a model would pick; their choices and eye movements were recorded. Read more about this study
- Who is it for?
- Ages 3 to 10 yearsHealthy volunteers can take part
- Conditions the study is for
- Autism Spectrum Disorder (ASD), Intellectual Disability
- How many people
- 80 participants
- Where
- 1 siteChina
- Study dates
- 15 Dec 2025to 27 Mar 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 3 to 10 years
- All sexes
- Healthy volunteers accepted
- Child
Study population: A total of 80 children (aged 3-10 years) were initially recruited and divided into three groups: 29 typically developing (TD) children (25 boys, 4 girls) from a kindergarten or primary school in Sichuan Province; 26 children with autism spectrum disorder (ASD) (20 boys, 6 girls) from a local disability federation or autism rehabilitation center in Chengdu, Sichuan Province, all clinically diagnosed and assessed with the Autism Diagnostic Observation Schedule (ADOS); and 25 children with intellectual disability (ID) (14 boys, 11 girls) from a disability federation or rehabilitation center in Chengdu, Sichuan Province, all clinically diagnosed. Based on eye-tracking data, 4 ASD participants and 1 ID participant whose total fixation duration accounted for less than 50% of the total trial time were excluded. Consequently, the final sample included 29 TD children (25 boys, 4 girls), 22 ASD children (18 boys, 4 girls), and 24 ID children (13 boys, 11 girls) for data analysis.
Who may be able to join
- Children clinically diagnosed with Autism Spectrum Disorder (ASD). Typically developing (TD) children with no developmental or neurological disorders.
- Children clinically diagnosed with Intellectual Disability (ID).
- Common criteria for all groups: Normal or corrected-to-normal vision, no color vision deficiencies, normal hearing, and written informed consent provided by their legal guardians.
Who cannot join
- Failure to meet the study's group-specific screening cutoffs on the Social Responsiveness Scale (SRS) and Social Communication Questionnaire (SCQ).
- Failure to meet the study's group-specific screening cutoffs on the Autism Diagnostic Observation Schedule (ADOS).
- Known genetic syndromes, significant hearing loss, or uncorrectable visual impairment.
Trial locations and contacts
1 site in 1 country.
China1 site
School of Foreign Languages, University of Electronic Science and Technology of China
Chengdu, Sichuan, 611731
About this study
Official title: Exploration of Verbal Intention and Gaze Clues Characteristics in Children With Autism: Based on Eye Tracking Technology
A 2×2×3 mixed design (intent word × object type × group: TD, ASD, ID) was used. Age-matched children watched videos and judged which object a model would pick; their choices and eye movements were recorded.
Read the detailed description
A 2 (intent word: like, dislike) × 2 (object type: mentioned, unmentioned) × 3 (participant group: ASD, TD, ID) mixed experimental design was adopted. Children from the three age-matched groups (29 TD, 22 ASD, 24 ID) completed a video-watching task. In the video, a model was presented with two objects and uttered a sentence containing an intent word, a verb, and a noun, such as "I like to eat oranges." Based on the intent word, trials were divided into "like" and "dislike" conditions. Objects were classified as "mentioned" or "unmentioned" according to the verb and noun used. Participants were required to judge which object the model would pick while watching the video. Their choice responses and eye movements were recorded.
- Keywords
- Joint Attention, Action Prediction, eye tracking
- Medical subject headings
- Autism Spectrum Disorder, Intellectual Disability
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Autism Spectrum Disorder (ASD) Group | Not described | |
| Typically Developing (TD) Group | Not described | |
| Intellectual Disability（ID）Group | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Percentage of Total Fixation Duration on Objects
Percentage of Total Fixation Duration on Objects = (Total time fixating on target objects ÷ Total fixation duration across the scene) × 100%. It measures how much of overall viewing time is spent attending to predefined objects, reflecting attentional priority and object-driven cognitive engagement, normalized for individual differences.
Measured: During the full 13 seconds video presentation
The time to first fixation on an object within each defined TOI (Time of Interest)
Time to First Fixation on an Object within a TOI = time elapsed from TOI onset until the first fixation lands on that object. It measures how quickly attention is drawn to a target, reflecting salience or search efficiency. Shorter times indicate faster capture.
Measured: During the 0-2 s, 2-6 s, and 6-8 s intervals of video
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 May 2026
- Study start15 Dec 2025
- Primary completion29 Jan 2026
- Study completion27 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Autism Spectrum Disorder (ASD)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 80 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Electronic Science and Technology of China
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Shan Gao, University of Electronic Science and Technology of China
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07597694
- Sponsor's protocol ID
- UESTC-GazeLab-04
- Status last verified
- May 2026
- First submitted
- 6 May 2026
- Last updated
- 19 May 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 19 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Exploration of Verbal Intention and Gaze Clues Characteristics in Children With Autism: Based on Eye Tracking Technology
- ClinicalTrials.gov ID
- NCT07597694
- Acronym / sponsor ID
- UESTC-GazeLab-04
- Keywords
- Joint Attention, Action Prediction, eye tracking
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 80 participants (actual)
- Lead sponsor
- University of Electronic Science and Technology of ChinaUniversity, hospital or other
- Study start
- 15 Dec 2025 (actual)
- Primary completion
- 29 Jan 2026 (actual)
- Study completion
- 27 Mar 2026 (actual)
- First posted
- 19 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
A 2×2×3 mixed design (intent word × object type × group: TD, ASD, ID) was used. Age-matched children watched videos and judged which object a model would pick; their choices and eye movements were recorded.
Detailed description
A 2 (intent word: like, dislike) × 2 (object type: mentioned, unmentioned) × 3 (participant group: ASD, TD, ID) mixed experimental design was adopted. Children from the three age-matched groups (29 TD, 22 ASD, 24 ID) completed a video-watching task. In the video, a model was presented with two objects and uttered a sentence containing an intent word, a verb, and a noun, such as "I like to eat oranges." Based on the intent word, trials were divided into "like" and "dislike" conditions. Objects were classified as "mentioned" or "unmentioned" according to the verb and noun used. Participants were required to judge which object the model would pick while watching the video. Their choice responses and eye movements were recorded.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Autism Spectrum Disorder (ASD) Group | – | – |
| Typically Developing (TD) Group | – | – |
| Intellectual Disability（ID）Group | – | – |
Who may qualify
- Ages
- 3 to 10 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
- Study population
- A total of 80 children (aged 3-10 years) were initially recruited and divided into three groups: 29 typically developing (TD) children (25 boys, 4 girls) from a kindergarten or primary school in Sichuan Province; 26 children with autism spectrum disorder (ASD) (20 boys, 6 girls) from a local disability federation or autism rehabilitation center in Chengdu, Sichuan Province, all clinically diagnosed and assessed with the Autism Diagnostic Observation Schedule (ADOS); and 25 children with intellectual disability (ID) (14 boys, 11 girls) from a disability federation or rehabilitation center in Chengdu, Sichuan Province, all clinically diagnosed. Based on eye-tracking data, 4 ASD participants and 1 ID participant whose total fixation duration accounted for less than 50% of the total trial time were excluded. Consequently, the final sample included 29 TD children (25 boys, 4 girls), 22 ASD children (18 boys, 4 girls), and 24 ID children (13 boys, 11 girls) for data analysis.
Key inclusion criteria (3 listed)
- Children clinically diagnosed with Autism Spectrum Disorder (ASD). Typically developing (TD) children with no developmental or neurological disorders.
- Children clinically diagnosed with Intellectual Disability (ID).
- Common criteria for all groups: Normal or corrected-to-normal vision, no color vision deficiencies, normal hearing, and written informed consent provided by their legal guardians.
Key exclusion criteria (3 listed)
- Failure to meet the study's group-specific screening cutoffs on the Social Responsiveness Scale (SRS) and Social Communication Questionnaire (SCQ).
- Failure to meet the study's group-specific screening cutoffs on the Autism Diagnostic Observation Schedule (ADOS).
- Known genetic syndromes, significant hearing loss, or uncorrectable visual impairment.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Percentage of Total Fixation Duration on Objects
Time frame: During the full 13 seconds video presentation
Percentage of Total Fixation Duration on Objects = (Total time fixating on target objects ÷ Total fixation duration across the scene) × 100%. It measures how much of overall viewing time is spent attending to predefined objects, reflecting attentional priority and object-driven cognitive engagement, normalized for individual differences.
The time to first fixation on an object within each defined TOI (Time of Interest)
Time frame: During the 0-2 s, 2-6 s, and 6-8 s intervals of video
Time to First Fixation on an Object within a TOI = time elapsed from TOI onset until the first fixation lands on that object. It measures how quickly attention is drawn to a target, reflecting salience or search efficiency. Shorter times indicate faster capture.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 May 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Autism Spectrum Disorder (ASD) and Intellectual Disability, run by University of Electronic Science and Technology of China at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Percentage of Total Fixation Duration on Objects (time frame: During the full 13 seconds video presentation). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 May 2026.