Hip FractureCPTHNCT07597317
Fascia Iliaca vs Femoral Nerve Block in Hip Fracture Patients
A study testing Fascia Iliaca Compartment Block (FICB) in people with Hip Fracture and Postoperative Pain, run by Central Park Teaching Hospital, Lahore at 1 site in Pakistan.
Trial summary
Hip fractures are common orthopedic injuries, especially in older adults, and surgical repair such as hip arthroplasty is often required. Effective pain control is essential in these patients to allow proper positioning for spinal anesthesia, reduce patient discomfort, and improve overall perioperative outcomes. Read more about this study
- Who is it for?
- Ages 20 to 70 years
- Conditions the study is for
- Hip Fracture, Postoperative Pain, Peripheral Nerve Block
- What is being tested?
- Fascia Iliaca Compartment Block (FICB)
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- 1 sitePakistan
- Study dates
- 10 Jun 2024to 9 Dec 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Both genders, age 20 to 70 years, ASA Class I and II. All cases undergoing abdominal surgery under general
Who cannot join
- Documented cases of allergy to the drug used in study (assessed by record).
- Documented cases with end stage liver and renal disease (ALT/ AST > 2 times normal limit or serum creatinine > 2 mg/dl).
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparative Study of Fascia Iliaca Block Versus Femoral Nerve Block for Postoperative Pain Management in Hip Fractures
Hip fractures are common orthopedic injuries, especially in older adults, and surgical repair such as hip arthroplasty is often required. Effective pain control is essential in these patients to allow proper positioning for spinal anesthesia, reduce patient discomfort, and improve overall perioperative outcomes.
Two commonly used regional anesthesia techniques for pain relief in hip fracture patients are the Fascia Iliaca Compartment Block (FICB) and the Femoral Nerve Block (FNB). Both techniques aim to block pain signals from the femoral nerve and related nerves supplying the hip region. However, there is ongoing debate regarding which technique provides better analgesia during positioning for spinal anesthesia.
Read more
This study is a prospective, randomized controlled trial conducted at Central Park Teaching Hospital, Lahore. A total of 80 patients scheduled for hip arthroplasty will be enrolled and randomly divided into two equal groups. Group A will receive Fascia Iliaca Compartment Block, while Group B will receive Femoral Nerve Block. All patients will subsequently undergo spinal anesthesia as part of standard surgical care.
The primary objective of the study is to compare the effectiveness of FICB and FNB in reducing pain during patient positioning for spinal anesthesia. Pain will be measured using the Numeric Rating Scale (NRS), which is a standard 0-10 pain scoring system, assessed before the nerve block and during positioning for spinal anesthesia.
Standard monitoring will be used in all patients, including blood pressure, pulse oximetry, and electrocardiography. Both techniques will be performed using standard local anesthetic agents. Rescue analgesia will be provided if required to ensure patient safety and comfort.
Data will be analyzed using appropriate statistical methods, and pain scores will be compared between the two groups. A p-value of ≤0.05 will be considered statistically significant.
The study aims to determine which regional anesthesia technique provides superior analgesia during spinal anesthesia positioning in hip fracture patients. The findings may help improve pain management strategies, enhance patient comfort, and optimize perioperative care in orthopedic surgery.
Read the detailed description
Hip fractures represent a major cause of morbidity in orthopedic practice, particularly among elderly patients. Surgical management, including hemiarthroplasty or total hip arthroplasty, is frequently required to restore mobility and reduce complications associated with prolonged immobilization. Effective perioperative pain control is essential in these patients, not only to improve comfort but also to facilitate optimal positioning for neuraxial anesthesia and to reduce perioperative physiological stress responses.
Spinal anesthesia is widely preferred over general anesthesia in hip fracture surgery due to its advantages, including reduced intraoperative blood loss, lower risk of thromboembolic events, and better postoperative analgesia. However, positioning patients with acute hip fractures for spinal anesthesia is often challenging due to severe pain, which can lead to patient discomfort, hemodynamic instability, and difficulty in performing the procedure. Adequate pre-procedural analgesia is therefore essential.
Regional nerve blocks have emerged as an effective strategy for providing analgesia in hip fracture patients. Among these, the Fascia Iliaca Compartment Block (FICB) and the Femoral Nerve Block (FNB) are commonly used techniques. Both approaches aim to block sensory input from the femoral nerve and associated branches supplying the anterior thigh and hip region. Despite their widespread use, there is ongoing debate regarding their relative effectiveness, particularly in terms of pain control during positioning for spinal anesthesia.
FICB is a fascial plane block that targets the femoral nerve, lateral femoral cutaneous nerve, and occasionally the obturator nerve by depositing local anesthetic beneath the fascia iliaca. It is considered relatively easier to perform and may provide broader sensory coverage. In contrast, FNB is a more targeted nerve block that specifically anesthetizes the femoral nerve. While FNB may provide effective analgesia, its narrower coverage may limit its efficacy in certain clinical scenarios involving hip fractures.
This study is designed as a prospective, randomized, controlled clinical trial conducted at the Orthopedics Operation Theatre of Central Park Teaching Hospital, Lahore. A total of 80 patients scheduled for elective hip arthroplasty will be enrolled after meeting eligibility criteria. Participants will be randomly allocated into two equal groups using a lottery-based randomization method. Group A will receive Fascia Iliaca Compartment Block, while Group B will receive Femoral Nerve Block. All patients will subsequently undergo standard spinal anesthesia as part of routine surgical care.
Both interventions will be performed under standard aseptic conditions using established anatomical landmark techniques. A uniform local anesthetic solution will be administered in both groups to ensure comparability. Standard intraoperative monitoring, including non-invasive blood pressure, electrocardiography, and pulse oximetry, will be applied to all patients throughout the procedure.
The primary outcome measure of this study is the comparison of pain scores during positioning for spinal anesthesia between the two groups. Pain will be assessed using the Numeric Rating Scale (NRS), a validated 11-point scale ranging from 0 (no pain) to 10 (worst possible pain). Pain assessments will be recorded prior to nerve block administration and during patient positioning for spinal anesthesia.
Secondary outcomes include baseline pain scores before intervention, adequacy of sensory block assessed by pinprick and cold sensation testing, and requirement for rescue analgesia if pain exceeds acceptable thresholds. Rescue analgesia, if required, will be administered using intravenous nalbuphine in standardized doses to ensure patient comfort and safety.
Data will be collected using a structured proforma and entered into SPSS version 25 for statistical analysis. Continuous variables will be expressed as mean and standard deviation, while categorical variables will be reported as frequencies and percentages. Independent sample t-tests will be used to compare mean pain scores between groups. Chi-square tests may be applied for categorical variables where appropriate. A p-value of ≤0.05 will be considered statistically significant.
Stratified analysis will be performed based on age, gender, and body mass index to control for potential confounding factors. This will help assess the consistency of analgesic efficacy across different patient subgroups.
Ethical approval for the study has been obtained from the institutional ethics committee of Central Park Teaching Hospital, Lahore. Written informed consent will be obtained from all participants prior to enrollment. Patient confidentiality will be strictly maintained throughout the study, and participation will not interfere with standard clinical care.
The findings of this study are expected to contribute valuable evidence regarding the comparative effectiveness of Fascia Iliaca Compartment Block and Femoral Nerve Block in hip fracture patients. The results may assist anesthesiologists and orthopedic surgeons in selecting the most effective regional anesthesia technique for improving patient comfort and facilitating spinal anesthesia positioning.
- Being tested
- Fascia Iliaca Compartment Block (FICB)
- Keywords
- Fascia Iliaca Compartment Block, Anagesia, Hip Fracture, Postoperative Pain, Peripheral Nerve Blcok, Femoral Nerve
- Medical subject headings
- Hip Fractures, Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Fascia Iliaca Compartment Block (FICB)Procedure or surgery
Fascia Iliaca Compartment Block (FICB) was administered prior to spinal anesthesia under aseptic conditions using the anatomical landmark technique. A needle was inserted below the inguinal ligament to access the fascia iliaca compartment. After confirmation of correct placement by loss of resistance and negative aspiration, 0.3 ml/kg of 1.5% lignocaine with adrenaline was injected. This approach aimed to block the femoral, lateral femoral cutaneous, and obturator nerves, providing broader analgesic coverage for the hip region during positioning for spinal anesthesia.
| Study group | Role | What they receive |
|---|---|---|
| Fascia Iliaca Compartment Block (FICB) | Experimental | Patients in this arm received a Fascia Iliaca Compartment Block (FICB) prior to spinal anesthesia. The block was performed under standard aseptic precautions using the anatomical landmark technique. After negative aspiration, 0.3 ml/kg of 1.5% lignocaine with adrenaline was injected beneath the fascia iliaca to achieve analgesia of the femoral, lateral femoral cutaneous, and obturator nerve territories. Pain was assessed using the Numeric Rating Scale (NRS) during positioning for spinal anesthesia. All patients then underwent standard spinal anesthesia. Receives: Procedure: Fascia Iliaca Compartment Block (FICB) |
| Femoral Nerve Block (FNB) | Active comparator | Patients in this arm received a Femoral Nerve Block (FNB) before spinal anesthesia under standard aseptic conditions using anatomical landmark technique. The femoral nerve was identified lateral to the femoral artery at the inguinal crease. After negative aspiration, 0.3 ml/kg of 1.5% lignocaine with adrenaline was injected to achieve femoral nerve blockade. The block provided analgesia to the anterior thigh and hip region. Pain was assessed using the Numeric Rating Scale (NRS) during positioning for spinal anesthesia. All patients then received standard spinal anesthesia for surgery. Receives: Procedure: Fascia Iliaca Compartment Block (FICB) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain score during positioning for spinal anesthesia
Pain was measured using the Numeric Rating Scale (NRS) from 0-10, where 0 indicated no pain and 10 indicated worst pain. The score was recorded during patient positioning for spinal anesthesia after administration of Fascia Iliaca Compartment Block or Femoral Nerve Block to compare analgesic effectiveness between groups.
Measured: During spinal anesthesia positioning (approximately 10-15 minutes after nerve block)
Secondary outcomes (4)
Pain score before nerve block
Baseline pain was assessed using the Numeric Rating Scale (NRS) prior to administration of Fascia Iliaca or Femoral Nerve Block to ensure comparability between groups.
Measured: Immediately before nerve block administration
Block effectiveness (sensory assessment)
Effectiveness of the block was assessed using pinprick and cold sensation testing over femoral nerve distribution to confirm adequate sensory blockade after FICB or FNB.
Measured: 5-10 minutes after nerve block administration
Requirement of rescue analgesia
Need for rescue analgesia (intravenous nalbuphine 4 mg) was recorded if NRS score remained >4 during positioning, indicating inadequate pain control.
Measured: During spinal anesthesia positioning
Ease/duration of spinal anesthesia positioning
Time required for successful positioning and completion of spinal anesthesia was recorded as an indicator of analgesic effectiveness of the block.
Measured: During spinal anesthesia procedure (from positioning start to successful SAB completion)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 May 2026
- Study start10 Jun 2024
- Primary completion9 Dec 2024
- Study completion9 Dec 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Hip FractureStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Prospective, randomized, parallel-group interventional study. Eighty hip arthroplasty patients will be allocated into two equal groups. Group A receives Fascia Iliaca Compartment Block (FICB) and Group B receives Femoral Nerve Block (FNB) using standard local anesthetic technique. All patients undergo spinal anesthesia. Primary outcome is pain during positioning for spinal anesthesia measured by Numeric Rating Scale (NRS). Both interventions are compared for analgesic efficacy.
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 80 participants (actual)
Sponsor and investigators
- Lead sponsor
- Central Park Teaching Hospital, Lahore
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Dr. Mehvish Saif, Central Park Teaching Hospital, Lahore
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07597317
- Sponsor's protocol ID
- Central Park TH
- Other IDs
- CPMC/IRB-No/1448A
- Acronym
- CPTH
- Status last verified
- May 2026
- First submitted
- 13 May 2026
- Last updated
- 19 May 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
3. Marzuki HN, Zahirah I, Lau MN, Kuppusamy E, Mustapha NM, Ashari A. Likert scale versus the visual analogue scale in evaluating dentofacial aesthetics: A systematic review. Australas Orthod J. 2024;40:158-68.
Poredos P, Poredos P, Jezovnik MK, Mavric A, Leben L, Mijovski MB, Maia P, Haddad S, Fareed J. Time Course of Inflammatory and Procoagulant Markers in the Early Period After Total Hip Replacement. Clin Appl Thromb Hemost. 2021 Jan-Dec;27:1076029620985941. doi: 10.1177/1076029620985941.
PubMed 33529054Hayashi M, Yamamoto N, Kuroda N, Kano K, Miura T, Kamimura Y, Shiroshita A. Peripheral Nerve Blocks in the Preoperative Management of Hip Fractures: A Systematic Review and Network Meta-Analysis. Ann Emerg Med. 2024 Jun;83(6):522-538. doi: 10.1016/j.annemergmed.2024.01.024. Epub 2024 Feb 22.
PubMed 383859104. Lamb JN, Nix O, Al-Wizni A, West R, Pandit H. Mortality after postoperative periprosthetic fracture of the femur after hip arthroplasty in the last decade: meta-analysis of 35 cohort studies including 4841 patients. J Arthroplasty. 2022;37(2):398-405. 5. Werner M, Macke C, Gogol M, Krettek C, Liodakis E. Differences in hip fracture care in Europe: a systematic review of recent annual reports of hip fracture registries. Eur J Trauma Emergency Surg. 2022:1-4. 6. Ghimire A, Bhattarai B, Koirala S, Subedi A. Analgesia before performing subarachnoid block in the sitting position in patients with proximal femoral fracture: a comparison between fascia iliaca block and femoral nerve block. Kathmandu Univ Med J. 2015;13(50):152-5. 7. Bantie M, Mola S, Girma T, Aweke Z, Neme D, Zemedkun A. Comparing analgesic effect of intravenous fentanyl, femoral nerve block and fascia iliaca block during spinal anesthesia positioning in elective adult patients undergoing femoral fracture surgery: a randomized controlled trial. J Pain Res. 2020:3139-46. 8. Chen L, Shen Y, Liu S, Cao Y, Zhu Z. Ultrasound-guided supra-inguinal fascia Iliaca compartment block for older adults admitted to the emergency department with hip fracture: a randomized controlled, double-blind clinical trial. BMC geriatrics. 2021;21:1-8. 9. Jain N, Mathur PR, Patodi V, Singh S. A comparative study of ultrasound-guided femoral nerve block versus fascia iliaca compartment block in patients with fracture femur for reducing pain associated with positioning for subarachnoid block. Indian J Pain. 2018;32(3):150-5. 10. Rasappan K, Chua IT, Tey JB, Ho SW. The continuous infusion fascia iliaca compartment block: a safe and effective analgesic modality in geriatric hip fracture patients. Archives Orthop Trauma Surg. 2021;141:29-37.
Study at a glance
From the registry record, last updated by the sponsor on 19 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Study of Fascia Iliaca Block Versus Femoral Nerve Block for Postoperative Pain Management in Hip Fractures
- ClinicalTrials.gov ID
- NCT07597317
- Acronym / sponsor ID
- CPTH / Central Park TH
- Keywords
- Fascia Iliaca Compartment Block, Anagesia, Hip Fracture, Postoperative Pain, Peripheral Nerve Blcok, Femoral Nerve
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 80 participants (actual)
- Lead sponsor
- Central Park Teaching Hospital, LahoreUniversity, hospital or other
- Study start
- 10 Jun 2024 (actual)
- Primary completion
- 9 Dec 2024 (actual)
- Study completion
- 9 Dec 2024 (actual)
- First posted
- 19 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Hip fractures are common orthopedic injuries, especially in older adults, and surgical repair such as hip arthroplasty is often required. Effective pain control is essential in these patients to allow proper positioning for spinal anesthesia, reduce patient discomfort, and improve overall perioperative outcomes.
Two commonly used regional anesthesia techniques for pain relief in hip fracture patients are the Fascia Iliaca Compartment Block (FICB) and the Femoral Nerve Block (FNB). Both techniques aim to block pain signals from the femoral nerve and related nerves supplying the hip region. However, there is ongoing debate regarding which technique provides better analgesia during positioning for spinal anesthesia.
This study is a prospective, randomized controlled trial conducted at Central Park Teaching Hospital, Lahore. A total of 80 patients scheduled for hip arthroplasty will be enrolled and randomly divided into two equal groups. Group A will receive Fascia Iliaca Compartment Block, while Group B will receive Femoral Nerve Block. All patients will subsequently undergo spinal anesthesia as part of standard surgical care.
The primary objective of the study is to compare the effectiveness of FICB and FNB in reducing pain during patient positioning for spinal anesthesia. Pain will be measured using the Numeric Rating Scale (NRS), which is a standard 0-10 pain scoring system, assessed before the nerve block and during positioning for spinal anesthesia.
Standard monitoring will be used in all patients, including blood pressure, pulse oximetry, and electrocardiography. Both techniques will be performed using standard local anesthetic agents. Rescue analgesia will be provided if required to ensure patient safety and comfort.
Data will be analyzed using appropriate statistical methods, and pain scores will be compared between the two groups. A p-value of ≤0.05 will be considered statistically significant.
The study aims to determine which regional anesthesia technique provides superior analgesia during spinal anesthesia positioning in hip fracture patients. The findings may help improve pain management strategies, enhance patient comfort, and optimize perioperative care in orthopedic surgery.
Detailed description
Hip fractures represent a major cause of morbidity in orthopedic practice, particularly among elderly patients. Surgical management, including hemiarthroplasty or total hip arthroplasty, is frequently required to restore mobility and reduce complications associated with prolonged immobilization. Effective perioperative pain control is essential in these patients, not only to improve comfort but also to facilitate optimal positioning for neuraxial anesthesia and to reduce perioperative physiological stress responses.
Spinal anesthesia is widely preferred over general anesthesia in hip fracture surgery due to its advantages, including reduced intraoperative blood loss, lower risk of thromboembolic events, and better postoperative analgesia. However, positioning patients with acute hip fractures for spinal anesthesia is often challenging due to severe pain, which can lead to patient discomfort, hemodynamic instability, and difficulty in performing the procedure. Adequate pre-procedural analgesia is therefore essential.
Regional nerve blocks have emerged as an effective strategy for providing analgesia in hip fracture patients. Among these, the Fascia Iliaca Compartment Block (FICB) and the Femoral Nerve Block (FNB) are commonly used techniques. Both approaches aim to block sensory input from the femoral nerve and associated branches supplying the anterior thigh and hip region. Despite their widespread use, there is ongoing debate regarding their relative effectiveness, particularly in terms of pain control during positioning for spinal anesthesia.
FICB is a fascial plane block that targets the femoral nerve, lateral femoral cutaneous nerve, and occasionally the obturator nerve by depositing local anesthetic beneath the fascia iliaca. It is considered relatively easier to perform and may provide broader sensory coverage. In contrast, FNB is a more targeted nerve block that specifically anesthetizes the femoral nerve. While FNB may provide effective analgesia, its narrower coverage may limit its efficacy in certain clinical scenarios involving hip fractures.
This study is designed as a prospective, randomized, controlled clinical trial conducted at the Orthopedics Operation Theatre of Central Park Teaching Hospital, Lahore. A total of 80 patients scheduled for elective hip arthroplasty will be enrolled after meeting eligibility criteria. Participants will be randomly allocated into two equal groups using a lottery-based randomization method. Group A will receive Fascia Iliaca Compartment Block, while Group B will receive Femoral Nerve Block. All patients will subsequently undergo standard spinal anesthesia as part of routine surgical care.
Both interventions will be performed under standard aseptic conditions using established anatomical landmark techniques. A uniform local anesthetic solution will be administered in both groups to ensure comparability. Standard intraoperative monitoring, including non-invasive blood pressure, electrocardiography, and pulse oximetry, will be applied to all patients throughout the procedure.
The primary outcome measure of this study is the comparison of pain scores during positioning for spinal anesthesia between the two groups. Pain will be assessed using the Numeric Rating Scale (NRS), a validated 11-point scale ranging from 0 (no pain) to 10 (worst possible pain). Pain assessments will be recorded prior to nerve block administration and during patient positioning for spinal anesthesia.
Secondary outcomes include baseline pain scores before intervention, adequacy of sensory block assessed by pinprick and cold sensation testing, and requirement for rescue analgesia if pain exceeds acceptable thresholds. Rescue analgesia, if required, will be administered using intravenous nalbuphine in standardized doses to ensure patient comfort and safety.
Data will be collected using a structured proforma and entered into SPSS version 25 for statistical analysis. Continuous variables will be expressed as mean and standard deviation, while categorical variables will be reported as frequencies and percentages. Independent sample t-tests will be used to compare mean pain scores between groups. Chi-square tests may be applied for categorical variables where appropriate. A p-value of ≤0.05 will be considered statistically significant.
Stratified analysis will be performed based on age, gender, and body mass index to control for potential confounding factors. This will help assess the consistency of analgesic efficacy across different patient subgroups.
Ethical approval for the study has been obtained from the institutional ethics committee of Central Park Teaching Hospital, Lahore. Written informed consent will be obtained from all participants prior to enrollment. Patient confidentiality will be strictly maintained throughout the study, and participation will not interfere with standard clinical care.
The findings of this study are expected to contribute valuable evidence regarding the comparative effectiveness of Fascia Iliaca Compartment Block and Femoral Nerve Block in hip fracture patients. The results may assist anesthesiologists and orthopedic surgeons in selecting the most effective regional anesthesia technique for improving patient comfort and facilitating spinal anesthesia positioning.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- Prospective, randomized, parallel-group interventional study. Eighty hip arthroplasty patients will be allocated into two equal groups. Group A receives Fascia Iliaca Compartment Block (FICB) and Group B receives Femoral Nerve Block (FNB) using standard local anesthetic technique. All patients undergo spinal anesthesia. Primary outcome is pain during positioning for spinal anesthesia measured by Numeric Rating Scale (NRS). Both interventions are compared for analgesic efficacy.
| Arm | Type | Receives |
|---|---|---|
| Fascia Iliaca Compartment Block (FICB) | Experimental | Procedure: Fascia Iliaca Compartment Block (FICB)Patients in this arm received a Fascia Iliaca Compartment Block (FICB) prior to spinal anesthesia. The block was performed under standard aseptic precautions using the anatomical landmark technique. After negative aspiration, 0.3 ml/kg of 1.5% lignocaine with adrenaline was injected beneath the fascia iliaca to achieve analgesia of the femoral, lateral femoral cutaneous, and obturator nerve territories. Pain was assessed using the Numeric Rating Scale (NRS) during positioning for spinal anesthesia. All patients then underwent standard spinal anesthesia. |
| Femoral Nerve Block (FNB) | Active comparator | Procedure: Fascia Iliaca Compartment Block (FICB)Patients in this arm received a Femoral Nerve Block (FNB) before spinal anesthesia under standard aseptic conditions using anatomical landmark technique. The femoral nerve was identified lateral to the femoral artery at the inguinal crease. After negative aspiration, 0.3 ml/kg of 1.5% lignocaine with adrenaline was injected to achieve femoral nerve blockade. The block provided analgesia to the anterior thigh and hip region. Pain was assessed using the Numeric Rating Scale (NRS) during positioning for spinal anesthesia. All patients then received standard spinal anesthesia for surgery. |
Who may qualify
- Ages
- 20 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Both genders, age 20 to 70 years, ASA Class I and II. All cases undergoing abdominal surgery under general
Key exclusion criteria (2 listed)
- Documented cases of allergy to the drug used in study (assessed by record).
- Documented cases with end stage liver and renal disease (ALT/ AST > 2 times normal limit or serum creatinine > 2 mg/dl).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Fascia Iliaca Compartment Block (FICB)Fascia Iliaca Compartment Block (FICB) was administered prior to spinal anesthesia under aseptic conditions using the anatomical landmark technique. A needle was inserted below the inguinal ligament to access the fascia iliaca compartment. After confirmation of correct placement by loss of resistance and negative aspiration, 0.3 ml/kg of 1.5% lignocaine with adrenaline was injected. This approach aimed to block the femoral, lateral femoral cutaneous, and obturator nerves, providing broader analgesic coverage for the hip region during positioning for spinal anesthesia. | Procedure or surgery | Fascia Iliaca Compartment Block (FICB), Femoral Nerve Block (FNB) |
Primary outcome
Pain score during positioning for spinal anesthesia
Time frame: During spinal anesthesia positioning (approximately 10-15 minutes after nerve block)
Pain was measured using the Numeric Rating Scale (NRS) from 0-10, where 0 indicated no pain and 10 indicated worst pain. The score was recorded during patient positioning for spinal anesthesia after administration of Fascia Iliaca Compartment Block or Femoral Nerve Block to compare analgesic effectiveness between groups.
4 secondary outcomes
Pain score before nerve block
Time frame: Immediately before nerve block administration
Block effectiveness (sensory assessment)
Time frame: 5-10 minutes after nerve block administration
Requirement of rescue analgesia
Time frame: During spinal anesthesia positioning
Ease/duration of spinal anesthesia positioning
Time frame: During spinal anesthesia procedure (from positioning start to successful SAB completion)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 May 2026.
- Background3. Marzuki HN, Zahirah I, Lau MN, Kuppusamy E, Mustapha NM, Ashari A. Likert scale versus the visual analogue scale in evaluating dentofacial aesthetics: A systematic review. Australas Orthod J. 2024;40:158-68.
- Background: PubMed 33529054Poredos P, Poredos P, Jezovnik MK, Mavric A, Leben L, Mijovski MB, Maia P, Haddad S, Fareed J. Time Course of Inflammatory and Procoagulant Markers in the Early Period After Total Hip Replacement. Clin Appl Thromb Hemost. 2021 Jan-Dec;27:1076029620985941. doi: 10.1177/1076029620985941.
- Background: PubMed 38385910Hayashi M, Yamamoto N, Kuroda N, Kano K, Miura T, Kamimura Y, Shiroshita A. Peripheral Nerve Blocks in the Preoperative Management of Hip Fractures: A Systematic Review and Network Meta-Analysis. Ann Emerg Med. 2024 Jun;83(6):522-538. doi: 10.1016/j.annemergmed.2024.01.024. Epub 2024 Feb 22.
- Results publication4. Lamb JN, Nix O, Al-Wizni A, West R, Pandit H. Mortality after postoperative periprosthetic fracture of the femur after hip arthroplasty in the last decade: meta-analysis of 35 cohort studies including 4841 patients. J Arthroplasty. 2022;37(2):398-405. 5. Werner M, Macke C, Gogol M, Krettek C, Liodakis E. Differences in hip fracture care in Europe: a systematic review of recent annual reports of hip fracture registries. Eur J Trauma Emergency Surg. 2022:1-4. 6. Ghimire A, Bhattarai B, Koirala S, Subedi A. Analgesia before performing subarachnoid block in the sitting position in patients with proximal femoral fracture: a comparison between fascia iliaca block and femoral nerve block. Kathmandu Univ Med J. 2015;13(50):152-5. 7. Bantie M, Mola S, Girma T, Aweke Z, Neme D, Zemedkun A. Comparing analgesic effect of intravenous fentanyl, femoral nerve block and fascia iliaca block during spinal anesthesia positioning in elective adult patients undergoing femoral fracture surgery: a randomized controlled trial. J Pain Res. 2020:3139-46. 8. Chen L, Shen Y, Liu S, Cao Y, Zhu Z. Ultrasound-guided supra-inguinal fascia Iliaca compartment block for older adults admitted to the emergency department with hip fracture: a randomized controlled, double-blind clinical trial. BMC geriatrics. 2021;21:1-8. 9. Jain N, Mathur PR, Patodi V, Singh S. A comparative study of ultrasound-guided femoral nerve block versus fascia iliaca compartment block in patients with fracture femur for reducing pain associated with positioning for subarachnoid block. Indian J Pain. 2018;32(3):150-5. 10. Rasappan K, Chua IT, Tey JB, Ho SW. The continuous infusion fascia iliaca compartment block: a safe and effective analgesic modality in geriatric hip fracture patients. Archives Orthop Trauma Surg. 2021;141:29-37.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Fascia Iliaca Compartment Block (FICB) in people with Hip Fracture and Postoperative Pain, run by Central Park Teaching Hospital, Lahore at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain score during positioning for spinal anesthesia (time frame: During spinal anesthesia positioning (approximately 10-15 minutes after nerve block)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07597317, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 May 2026.