PRIMARY HYPERTENSIONSAPHNCT07577973
The Effect of Self-Acupressure on Blood Pressure, Stress, and Well-Being Levels in Individuals With Hypertension
A study testing Real Acupressure in people with PRIMARY HYPERTENSION, run by Abant Izzet Baysal University at 1 site in Turkey (Türkiye).
Trial summary
This randomized controlled trial examines the effects of nurse-led self-acupressure at HT7, LI4, PC6, and EX3 points on blood pressure, stress, and well-being in adults with primary hypertension. Participants are randomized to real acupressure, sham acupressure, or usual care groups for 2 weeks. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- PRIMARY HYPERTENSION
- What is being tested?
- Real Acupressure
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 72 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 7 Sep 2026to 30 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Aged 18-65 years
- Diagnosed with primary hypertension (Stage 1 or 2)
- Systolic blood pressure 130-179 mmHg or diastolic 80-109 mmHg
- Taking antihypertensive medication
- Able to understand and communicate in Turkish
- Willing to provide written informed consent
Who cannot join
- Secondary hypertension
- Pregnancy or lactation
- Severe cardiovascular disease (heart failure, myocardial infarction within 6 months)
- Stroke history within 6 months
- Skin lesions or infection at acupressure sites (HT7, LI4, PC6, EX3)
- Peripheral neuropathy affecting sensation
- Current use of anticoagulant therapy
- Participation in another clinical trial within 30 days
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
A Family Health Center in Duzce
Center, Düzce
Saadet Can Cicek, Associate Professor,PhD, +90 374 254 10 00, saadet.cancicek@ibu.edu.tr
About this study
Official title: The Effect of Self-Acupressure on Blood Pressure, Stress, and Well-Being Levels in Individuals With Hypertension: A Three-Arm Randomized Controlled Trial
This randomized controlled trial examines the effects of nurse-led self-acupressure at HT7, LI4, PC6, and EX3 points on blood pressure, stress, and well-being in adults with primary hypertension. Participants are randomized to real acupressure, sham acupressure, or usual care groups for 2 weeks.
- Conditions
- PRIMARY HYPERTENSION
- Being tested
- Real Acupressure, sham acupressure, Usual Care
- Keywords
- Acupressure Hypertension Self-care Nursing Stress Well-being Randomized Controlled Trial
- Medical subject headings
- Essential Hypertension
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Real AcupressureBehavioural
Acupressure applied to HT7 (Shenmen), LI4 (Hegu), PC6 (Neiguan) bilaterally, and EX3 (Yintang). Pressure applied for 15 seconds per point, 3 days per week for 2 weeks by trained researcher. Total session duration approximately 1 minute.
sham acupressureBehavioural
light pressure applied to non-acupoint sites 1-1.5 cm from HT7İLI4,PC6 and EX3 points for 15 seconds per site,3 days per week for 2 weeks
Usual CareOther
Standard hypertension management including prescribed antihypertensive medication and routine clinical nursing follow-up for 2 weeks. No acupressure applied.
| Study group | Role | What they receive |
|---|---|---|
| Real Acupressure Group | Experimental | participants receive acupressure on bilateral HT7,LI4,PC6 EX3 points. pressure applied for 15 seconds per point, 3 days per week, for 2 weeks Receives: Behavioral: Real Acupressure |
| sham/placebo | Sham comparator | Participants receive sham acupressure on non-acupoints located 1-1.5 cm away from HT7, LI4 , PC6, and EX3 points. Pressure applied for 15 seconds per site, 3 days per week, for 2 weeks to maintain participant blinding Receives: Behavioral: sham acupressure |
| control | Active comparator | Participants receive usual care for hypertension including prescribed antihypertensive medications and routine clinical nursing follow-up for 2 weeks. No acupressure intervention applied. Receives: Other: Usual Care |
What is being measured
The primary outcome is the main question the study is designed to answer.
change in blood pressure
change from baseline in systolic and diastolic blood pressure measured using an automated office blood pressure monitor at 2 weeks
Measured: baseline and week 2
Secondary outcomes (2)
change in perceived stress
Change from baseline in Perceived Stress Scale-14 (PSS-14) total score at 2 weeks. Scores range from 0 to 56, with higher scores indicating greater perceived stress
Measured: baseline, week 2
change in mental well-being
Change from baseline in Warwick-Edinburgh Mental Well-being Scale (WEMWBS) total score at 2 weeks. Scores range from 14 to 70, with higher scores indicating better mental well-being
Measured: baseline, week 2
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 May 2026
- Study start7 Sep 2026
- Primary completion1 Dec 2026 (estimated)
- Study completion30 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for PRIMARY HYPERTENSIONStudies of the same condition, open and under way.
- More trials run by Abant Izzet Baysal UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomized into 3 groups:real acupressure, sham acupressure, and usual care
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 72 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Abant Izzet Baysal University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Saadet Can Çiçek, Abant Izzet Baysal University
- Investigators
- Saadet Can Cicek, Associate Professor,PhD, Principal investigator, Abant Izzet Baysal University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07577973
- Sponsor's protocol ID
- AIBU-HTN-ACUP-2026-01
- Acronym
- SAPH
- Status last verified
- Nov 2026
- First submitted
- 5 May 2026
- Last updated
- 4 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared to protect participant confidentiality as stated in the informed consent form approved by the ethics committee. Data will only be accessible to the study team for the purposes of this study.
Study at a glance
From the registry record, last updated by the sponsor on 4 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Self-Acupressure on Blood Pressure, Stress, and Well-Being Levels in Individuals With Hypertension: A Three-Arm Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07577973
- Acronym / sponsor ID
- SAPH / AIBU-HTN-ACUP-2026-01
- Conditions
- PRIMARY HYPERTENSION
- Keywords
- Acupressure Hypertension Self-care Nursing Stress Well-being Randomized Controlled Trial
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 72 participants (estimated)
- Lead sponsor
- Abant Izzet Baysal UniversityUniversity, hospital or other
- Study start
- 7 Sep 2026 (actual)
- Primary completion
- 1 Dec 2026 (estimated)
- Study completion
- 30 Dec 2026 (estimated)
- First posted
- 11 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial examines the effects of nurse-led self-acupressure at HT7, LI4, PC6, and EX3 points on blood pressure, stress, and well-being in adults with primary hypertension. Participants are randomized to real acupressure, sham acupressure, or usual care groups for 2 weeks.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 3
- Model description
- Participants will be randomized into 3 groups:real acupressure, sham acupressure, and usual care
| Arm | Type | Receives |
|---|---|---|
| Real Acupressure Group | Experimental | Behavioral: Real Acupressureparticipants receive acupressure on bilateral HT7,LI4,PC6 EX3 points. pressure applied for 15 seconds per point, 3 days per week, for 2 weeks |
| sham/placebo | Sham comparator | Behavioral: sham acupressureParticipants receive sham acupressure on non-acupoints located 1-1.5 cm away from HT7, LI4 , PC6, and EX3 points. Pressure applied for 15 seconds per site, 3 days per week, for 2 weeks to maintain participant blinding |
| control | Active comparator | Other: Usual CareParticipants receive usual care for hypertension including prescribed antihypertensive medications and routine clinical nursing follow-up for 2 weeks. No acupressure intervention applied. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Aged 18-65 years
- Diagnosed with primary hypertension (Stage 1 or 2)
- Systolic blood pressure 130-179 mmHg or diastolic 80-109 mmHg
- Taking antihypertensive medication
- Able to understand and communicate in Turkish
Key exclusion criteria (8 listed)
- Secondary hypertension
- Pregnancy or lactation
- Severe cardiovascular disease (heart failure, myocardial infarction within 6 months)
- Stroke history within 6 months
- Skin lesions or infection at acupressure sites (HT7, LI4, PC6, EX3)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Real AcupressureAcupressure applied to HT7 (Shenmen), LI4 (Hegu), PC6 (Neiguan) bilaterally, and EX3 (Yintang). Pressure applied for 15 seconds per point, 3 days per week for 2 weeks by trained researcher. Total session duration approximately 1 minute. | Behavioural | Real Acupressure Group |
| sham acupressurelight pressure applied to non-acupoint sites 1-1.5 cm from HT7İLI4,PC6 and EX3 points for 15 seconds per site,3 days per week for 2 weeks | Behavioural | sham/placebo |
| Usual CareStandard hypertension management including prescribed antihypertensive medication and routine clinical nursing follow-up for 2 weeks. No acupressure applied. | Other | control |
Primary outcome
change in blood pressure
Time frame: baseline and week 2
change from baseline in systolic and diastolic blood pressure measured using an automated office blood pressure monitor at 2 weeks
2 secondary outcomes
change in perceived stress
Time frame: baseline, week 2
change in mental well-being
Time frame: baseline, week 2
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Nov 2026.
- Individual participant dataSharing planned: No. Individual participant data will not be shared to protect participant confidentiality as stated in the informed consent form approved by the ethics committee. Data will only be accessible to the study team for the purposes of this study.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Saadet Can Cicek, Associate Professor,PhD principal investigator
Abant Izzet Baysal University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Real Acupressure in people with PRIMARY HYPERTENSION, run by Abant Izzet Baysal University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 4 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Seymanur Ozdemir Arslan, MSc,Phd Candidate (+90 0380 523 7827, seymanurarslan@duzce.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
change in blood pressure (time frame: baseline and week 2). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Nov 2026.