Performance EnhancementCAF & FFTNCT07570030
CAF & Firefighters Performance
A study testing Caffeine (300 mg) in people with Performance Enhancement, run by Chih-Hui Chiu at 1 site in Taiwan.
Trial summary
The aim of the study being to investigate chewing caffeine-containing gum could effectively improve firefighters' balance under conditions of brain fatigue. Read more about this study
- Who is it for?
- Ages 20 to 40 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Performance Enhancement
- What is being tested?
- Caffeine (300 mg)
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 14 participants
- Where
- 1 siteTaiwan
- Study dates
- 1 Jul 2025to 25 Nov 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Active-duty members of the Special Search and Rescue Brigade
- Regularly perform firefighting and disaster relief duties
- Have fully recovered from sports injuries such as strains or sprains for at least 3 months
Who cannot join
- Members who are not part of the Special Search and Rescue Brigade.
- Individuals who do not regularly perform firefighting and disaster relief duties
- Participants who have not fully recovered from sports injuries for at least 3 months
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Caffeinated Chewing Gum on Functional Firefighting Balance Ability After GABA Supplementation
The aim of the study being to investigate chewing caffeine-containing gum could effectively improve firefighters' balance under conditions of brain fatigue.
Read the detailed description
14 healthy adult male active-duty firefighters as participants and used a crossover double-blind design, dividing them into a CAF trial and a PL trial. On the first day of the experiment, after the participants had taken sufficient time off and had a full night's sleep, they rested for 3 hours after dinner on the second day. Following the collection of saliva samples, baseline heart rate variability and firefighting ability tests were conducted. After the tests, the participants ingested 800 mg of GABA and rested for 30 minutes. After that, the participants chewed caffeinated gum containing 3 mg/kg (CAF trial) or caffeine-free placebo gum (PL trial) for 10 minutes, spit it out, rested for 15 minutes. The participants underwent eight firefighting balance tests, during which heart rate variability was measured. After the tests were completed, saliva samples were collected again.
- Conditions
- Performance Enhancement
- Being tested
- Caffeine (300 mg), Placebo
- Keywords
- firefighters
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Caffeine (300 mg)Dietary supplement
The participants chewing either caffeine Gum (CAF trial, containing 3 mg/kg of caffeine) or Placebo Gum (PL) for 10 minutes.
PlaceboOther
The participants chewing either caffeine Gum (CAF trial, containing 3 mg/kg of caffeine) or Placebo Gum (PL) for 10 minutes.
| Study group | Role | What they receive |
|---|---|---|
| intervention | Active comparator | Chewing caffeine gum for 10 minutes Receives: Dietary Supplement: Caffeine (300 mg); Other: Placebo |
| placebo | Placebo comparator | Chewing placebo gum for 10 minutes Receives: Dietary Supplement: Caffeine (300 mg); Other: Placebo |
What is being measured
The primary outcome is the main question the study is designed to answer.
firefighting balance test
Measure the time it takes to return
Measured: 15 minutes after intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 May 2026
- Study start1 Jul 2025
- Primary completion1 Jul 2025
- Study completion25 Nov 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Performance EnhancementStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 14 participants (actual)
Sponsor and investigators
- Lead sponsor
- Chih-Hui Chiu
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Chih-Hui Chiu, National Taiwan Sport University
- Investigators
- Chih Hui Chiu, Principal investigator, National Taiwan University of Sport
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07570030
- Sponsor's protocol ID
- 115-3
- Other IDs
- NTUS
- Acronym
- CAF & FFT
- Status last verified
- Apr 2026
- First submitted
- 28 Apr 2026
- Last updated
- 6 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Caffeinated Chewing Gum on Functional Firefighting Balance Ability After GABA Supplementation
- ClinicalTrials.gov ID
- NCT07570030
- Acronym / sponsor ID
- CAF & FFT / 115-3
- Conditions
- Performance Enhancement
- Keywords
- firefighters
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 14 participants (actual)
- Lead sponsor
- Chih-Hui ChiuUniversity, hospital or other
- Study start
- 1 Jul 2025 (actual)
- Primary completion
- 1 Jul 2025 (actual)
- Study completion
- 25 Nov 2025 (actual)
- First posted
- 6 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of the study being to investigate chewing caffeine-containing gum could effectively improve firefighters' balance under conditions of brain fatigue.
Detailed description
14 healthy adult male active-duty firefighters as participants and used a crossover double-blind design, dividing them into a CAF trial and a PL trial. On the first day of the experiment, after the participants had taken sufficient time off and had a full night's sleep, they rested for 3 hours after dinner on the second day. Following the collection of saliva samples, baseline heart rate variability and firefighting ability tests were conducted. After the tests, the participants ingested 800 mg of GABA and rested for 30 minutes. After that, the participants chewed caffeinated gum containing 3 mg/kg (CAF trial) or caffeine-free placebo gum (PL trial) for 10 minutes, spit it out, rested for 15 minutes. The participants underwent eight firefighting balance tests, during which heart rate variability was measured. After the tests were completed, saliva samples were collected again.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| intervention | Active comparator | Dietary Supplement: Caffeine (300 mg), Other: PlaceboChewing caffeine gum for 10 minutes |
| placebo | Placebo comparator | Dietary Supplement: Caffeine (300 mg), Other: PlaceboChewing placebo gum for 10 minutes |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Active-duty members of the Special Search and Rescue Brigade
- Regularly perform firefighting and disaster relief duties
- Have fully recovered from sports injuries such as strains or sprains for at least 3 months
Key exclusion criteria (3 listed)
- Members who are not part of the Special Search and Rescue Brigade.
- Individuals who do not regularly perform firefighting and disaster relief duties
- Participants who have not fully recovered from sports injuries for at least 3 months
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Caffeine (300 mg)The participants chewing either caffeine Gum (CAF trial, containing 3 mg/kg of caffeine) or Placebo Gum (PL) for 10 minutes. | Dietary supplement | intervention, placebo |
| PlaceboThe participants chewing either caffeine Gum (CAF trial, containing 3 mg/kg of caffeine) or Placebo Gum (PL) for 10 minutes. | Other | intervention, placebo |
Primary outcome
firefighting balance test
Time frame: 15 minutes after intervention
Measure the time it takes to return
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 May 2026.
- Individual participant dataSharing planned: No
Related trials for Performance Enhancement
Recruiting
The Efficacy of an IADL-based Non-immersive Virtual Reality Training Program to Enhance ADL Performance and Cognitive Function for Persons at Risk of Dementia
Cognitive Enhancement, Subjective Cognitive Decline (SCD)
Active, not recruiting
Effects of Blood Flow Restriction Training on Physical Function, Muscle Adaptations, and Performance in Roller Skaters
Athletic Performance Enhancement
Recruiting
Nutritional Intervention for Older Adults With Complete Dentures
Edentulism Complete, Denture, Complete
RecruitingObservational study
A Prospective Study to Develop and Clinically Validate an in Vitro Diagnostic Medical Device That Uses Blood to Classify Patients at High Risk for Breast Cancer
Breast Neoplasm
Recruiting
Bicentric Clinical Investigation to Assess Safety and Performance of LuxBoost IOL
Aphakia
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Chih Hui Chiu principal investigator
National Taiwan University of Sport
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Caffeine (300 mg) in people with Performance Enhancement, run by Chih-Hui Chiu at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
firefighting balance test (time frame: 15 minutes after intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 May 2026.