Game-Based LearningNCT07557719
Gamified Learning Methods and HPV Knowledge in Nursing Students
A study testing Gimkit-Based Game-Based Learning and Escape Room-Based Game-Based Learning in people with Game-Based Learning and Educational Intervention, run by Aydin Adnan Menderes University at 1 site in Turkey (Türkiye).
Trial summary
This study is a randomized controlled trial (RCT) with a pretest-posttest-follow-up design that compares the effectiveness of gamified teaching methods (Gimkit and educational escape room) with traditional theoretical education in improving undergraduate nursing students' Human Papillomavirus (HPV) knowledge and HPV… Read more about this study
- Who is it for?
- Ages 18 to 45 yearsHealthy volunteers can take part
- Conditions the study is for
- Game-Based Learning, Educational Intervention, Nursing Education
- What is being tested?
- Gimkit-Based Game-Based Learning and Escape Room-Based Game-Based Learning
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 90 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 17 Apr 2026to 13 Jun 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Being a third-year undergraduate nursing student enrolled in the Obstetrics and Gynecology Nursing course
- Voluntary participation
- Participation in all measurement points
- Ownership of a smartphone
- Internet access
- Having headphones.
- Exclusion Criteria Previous experience with Gimkit or educational escape room activities Incomplete data forms Not participating in intervention sessions Absence from the posttest or follow-up assessment
Who cannot join
None listed.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Gimkit and Escape Room Teaching Methods on Nursing Students' Knowledge and Literacy Levels Regarding Human Papillomavirus (HPV): A Randomized Controlled Trial
This study is a randomized controlled trial (RCT) with a pretest-posttest-follow-up design that compares the effectiveness of gamified teaching methods (Gimkit and educational escape room) with traditional theoretical education in improving undergraduate nursing students' Human Papillomavirus (HPV) knowledge and HPV literacy. Both HPV knowledge and HPV literacy were prespecified primary outcome measures in the study protocol. These outcomes represent related but distinct educational constructs and are reported separately to allow independent interpretation of each outcome.
Read the detailed description
This randomized controlled trial (RCT) with a pretest-posttest-follow-up design evaluated the effectiveness of two gamified teaching strategies in undergraduate nursing education. The study was conducted among third-year nursing students enrolled in the Obstetrics and Gynecology Nursing course at Aydın Adnan Menderes University.
Participants were randomly assigned to one of three groups:
- Gimkit-based gamification combined with theoretical education
- Educational escape room combined with theoretical education
- Control group (theoretical education only)
All participants received standardized theoretical instruction on Human Papillomavirus (HPV). Subsequently, participants in the intervention groups completed either the Gimkit or educational escape room activity, whereas the control group received no additional educational intervention.
Data were collected using the following instruments:
- Student Information Form
- Human Papillomavirus (HPV) Knowledge Scale
- Human Papillomavirus Literacy Scale (HPV-LS)
- Gameful Experience Scale (GAMEX)
Both HPV knowledge and HPV literacy were prespecified primary outcome measures in the study protocol. HPV knowledge and HPV literacy address related but distinct educational constructs and are reported separately to allow independent interpretation of each outcome.
Data were analyzed using IBM SPSS Statistics version 25.0. Descriptive statistics were calculated for all variables. Baseline continuous variables were compared using one-way analysis of variance (ANOVA), whereas categorical variables were analyzed using the chi-square test or Fisher's exact test, as appropriate. Changes in study outcomes over time were evaluated using two-way repeated-measures ANOVA with Bonferroni-adjusted pairwise comparisons, as appropriate. Statistical significance was set at p < 0.05.
- Being tested
- Gimkit-Based Game-Based Learning, Escape Room-Based Game-Based Learning
- Keywords
- Human Papillomavirus Infections, Knowledge, Game-based learning, Nursing education
- Medical subject headings
- Papillomavirus Infections
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Gimkit-Based Game-Based LearningBehavioural
Participants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by participation in a Gimkit-based digital quiz game consisting of multiple-choice and true/false questions designed to reinforce HPV-related knowledge.
Escape Room-Based Game-Based LearningBehavioural
Participants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by participation in structured escape room-based learning activities consisting of crossword puzzles, word search tasks, and matching exercises designed to reinforce HPV-related knowledge.
| Study group | Role | What they receive |
|---|---|---|
| Gimkit Group | Experimental | Participants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by a Gimkit-based digital quiz game consisting of multiple-choice and true/false questions. Receives: Behavioral: Gimkit-Based Game-Based Learning |
| Escape Room Group | Experimental | Participants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by participation in structured escape room-based learning activities consisting of crossword puzzles, word search tasks, and matching exercises designed to reinforce HPV-related knowledge through collaborative problem-solving. Receives: Behavioral: Escape Room-Based Game-Based Learning |
| Control Group | No intervention | Participants will receive standardized theoretical education on Human Papillomavirus (HPV) and will not participate in any gamified learning activities. |
What is being measured
The primary outcome is the main question the study is designed to answer.
HPV Knowledge Level
Human Papillomavirus (HPV) Knowledge Scale. Scores range from 0 to 33; higher scores indicate greater knowledge.
Measured: Baseline (Day 0, before theoretical education; 17 April 2026), immediately after theoretical education (Day 0; 17 April 2026), immediately after the intervention (Day 7; 24 April 2026), and follow-up (Day 28; 15 May 2026).
HPV Literacy Level
Human Papillomavirus (HPV) Literacy Scale. Scores range from 24 to 120; higher scores indicate higher literacy.
Measured: Baseline (Day 0, before theoretical education; 17 April 2026), immediately after theoretical education (Day 0; 17 April 2026), immediately after the intervention (Day 7; 24 April 2026), and follow-up (Day 28; 15 May 2026).
Secondary outcomes (1)
Gamified Learning Experience
Measured using the Gameful Experience Scale (GAMEX). Higher scores indicate a more positive gamified learning experience.
Measured: Immediately after completion of the gamified intervention (Day 7; 24 April 2026).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Apr 2026
- Study start17 Apr 2026
- Primary completion15 May 2026
- Study completion13 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Game-Based LearningStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Parallel Assignment. Participants were randomly assigned to one of three parallel groups: Gimkit plus theoretical education, educational escape room plus theoretical education, or theoretical education alone.
- Masking
- None (open label)
- Enrolment
- 90 participants (actual)
Sponsor and investigators
- Lead sponsor
- Aydin Adnan Menderes University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Nihal Taskiran, Aydin Adnan Menderes University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07557719
- Sponsor's protocol ID
- 2026/03/05- HPV
- Status last verified
- Jul 2026
- First submitted
- 20 Apr 2026
- Last updated
- 6 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Gimkit and Escape Room Teaching Methods on Nursing Students' Knowledge and Literacy Levels Regarding Human Papillomavirus (HPV): A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07557719
- Acronym / sponsor ID
- 2026/03/05- HPV
- Keywords
- Human Papillomavirus Infections, Knowledge, Game-based learning, Nursing education
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 90 participants (actual)
- Lead sponsor
- Aydin Adnan Menderes UniversityUniversity, hospital or other
- Study start
- 17 Apr 2026 (actual)
- Primary completion
- 15 May 2026 (actual)
- Study completion
- 13 Jun 2026 (actual)
- First posted
- 29 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is a randomized controlled trial (RCT) with a pretest-posttest-follow-up design that compares the effectiveness of gamified teaching methods (Gimkit and educational escape room) with traditional theoretical education in improving undergraduate nursing students' Human Papillomavirus (HPV) knowledge and HPV literacy. Both HPV knowledge and HPV literacy were prespecified primary outcome measures in the study protocol. These outcomes represent related but distinct educational constructs and are reported separately to allow independent interpretation of each outcome.
Detailed description
This randomized controlled trial (RCT) with a pretest-posttest-follow-up design evaluated the effectiveness of two gamified teaching strategies in undergraduate nursing education. The study was conducted among third-year nursing students enrolled in the Obstetrics and Gynecology Nursing course at Aydın Adnan Menderes University.
Participants were randomly assigned to one of three groups:
- Gimkit-based gamification combined with theoretical education
- Educational escape room combined with theoretical education
- Control group (theoretical education only)
All participants received standardized theoretical instruction on Human Papillomavirus (HPV). Subsequently, participants in the intervention groups completed either the Gimkit or educational escape room activity, whereas the control group received no additional educational intervention.
Data were collected using the following instruments:
- Student Information Form
- Human Papillomavirus (HPV) Knowledge Scale
- Human Papillomavirus Literacy Scale (HPV-LS)
- Gameful Experience Scale (GAMEX)
Both HPV knowledge and HPV literacy were prespecified primary outcome measures in the study protocol. HPV knowledge and HPV literacy address related but distinct educational constructs and are reported separately to allow independent interpretation of each outcome.
Data were analyzed using IBM SPSS Statistics version 25.0. Descriptive statistics were calculated for all variables. Baseline continuous variables were compared using one-way analysis of variance (ANOVA), whereas categorical variables were analyzed using the chi-square test or Fisher's exact test, as appropriate. Changes in study outcomes over time were evaluated using two-way repeated-measures ANOVA with Bonferroni-adjusted pairwise comparisons, as appropriate. Statistical significance was set at p < 0.05.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
- Model description
- Parallel Assignment. Participants were randomly assigned to one of three parallel groups: Gimkit plus theoretical education, educational escape room plus theoretical education, or theoretical education alone.
| Arm | Type | Receives |
|---|---|---|
| Gimkit Group | Experimental | Behavioral: Gimkit-Based Game-Based LearningParticipants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by a Gimkit-based digital quiz game consisting of multiple-choice and true/false questions. |
| Escape Room Group | Experimental | Behavioral: Escape Room-Based Game-Based LearningParticipants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by participation in structured escape room-based learning activities consisting of crossword puzzles, word search tasks, and matching exercises designed to reinforce HPV-related knowledge through collaborative problem-solving. |
| Control Group | No intervention | –Participants will receive standardized theoretical education on Human Papillomavirus (HPV) and will not participate in any gamified learning activities. |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- Being a third-year undergraduate nursing student enrolled in the Obstetrics and Gynecology Nursing course
- Voluntary participation
- Participation in all measurement points
- Ownership of a smartphone
- Internet access
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Gimkit-Based Game-Based LearningParticipants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by participation in a Gimkit-based digital quiz game consisting of multiple-choice and true/false questions designed to reinforce HPV-related knowledge. | Behavioural | Gimkit Group |
| Escape Room-Based Game-Based LearningParticipants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by participation in structured escape room-based learning activities consisting of crossword puzzles, word search tasks, and matching exercises designed to reinforce HPV-related knowledge. | Behavioural | Escape Room Group |
Primary outcome
HPV Knowledge Level
Time frame: Baseline (Day 0, before theoretical education; 17 April 2026), immediately after theoretical education (Day 0; 17 April 2026), immediately after the intervention (Day 7; 24 April 2026), and follow-up (Day 28; 15 May 2026).
Human Papillomavirus (HPV) Knowledge Scale. Scores range from 0 to 33; higher scores indicate greater knowledge.
HPV Literacy Level
Time frame: Baseline (Day 0, before theoretical education; 17 April 2026), immediately after theoretical education (Day 0; 17 April 2026), immediately after the intervention (Day 7; 24 April 2026), and follow-up (Day 28; 15 May 2026).
Human Papillomavirus (HPV) Literacy Scale. Scores range from 24 to 120; higher scores indicate higher literacy.
1 secondary outcome
Gamified Learning Experience
Time frame: Immediately after completion of the gamified intervention (Day 7; 24 April 2026).
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Jul 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Gimkit-Based Game-Based Learning and Escape Room-Based Game-Based Learning in people with Game-Based Learning and Educational Intervention, run by Aydin Adnan Menderes University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
HPV Knowledge Level (time frame: Baseline (Day 0, before theoretical education; 17 April 2026), immediately after theoretical education (Day 0; 17 April 2026), immediately after the intervention (Day 7; 24 April 2026), and follow-up (Day 28; 15 May 2026).). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Jul 2026.