PneumoniainterventionNCT07552116
Low Intensity Laser Therapy on Immune System Response Among Children With Pneumonia
A study testing low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements and received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. in people with Pneumonia, run by Badr University at 1 site in Egypt.
Trial summary
Objective: The aim of this study was to detect the impact of low intensity laser therapy on immune system response among DS children with pneumonia. Material and Methods: Forty DS children with bronchopneumonia, were included into ; group (A) received low intensity laser therapy, inspiratory muscle training in… Read more about this study
- Who is it for?
- Ages 3 to 5 years
- Conditions the study is for
- Pneumonia
- What is being tested?
- low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements and received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteEgypt
- Study dates
- 6 Apr 2026to 30 May 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 3 to 5 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Dawn Syndrome children with pneumonia
- Mean age of 3.73±1.82 year
- Children were in the first attack of bronchopneumonia.
Who cannot join
- Other chest disease
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Mona Mohamed Abdelkhalek
Cairo
Mona Mohamed Abdelkhalek, LECTURER, 002021024056108, 3m.sons@gmail.com
About this study
Official title: Impact of Low Intensity Laser Therapy on Immune System Response Among Children With Pneumonia
Objective: The aim of this study was to detect the impact of low intensity laser therapy on immune system response among DS children with pneumonia. Material and Methods: Forty DS children with bronchopneumonia, were included into ; group (A) received low intensity laser therapy, inspiratory muscle training in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.
Read the detailed description
The aim of this study was to detect the impact of low intensity laser therapy on immune system response among DS children with pneumonia. Material and Methods: Forty DS children with bronchopneumonia, mean age of 3.73±1.82 year and were included into 2 equal groups; group (A) received low intensity laser therapy, inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.
- Conditions
- Pneumonia
- Being tested
- low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements, received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.
- Keywords
- Laser, Immune, Pneumonia, Dawn syndrome
- Medical subject headings
- Pneumonia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. MeasurementsOther
Also called low intensity laser therapy, muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements
low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements
received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.Other
Also called inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.
received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.
| Study group | Role | What they receive |
|---|---|---|
| group (A) | Experimental | received low intensity laser therapy, inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment at a frequency of 3 sessions per week for one month Receives: Other: low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements; Other: received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. |
| group (B) | Experimental | received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Receives: Other: received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. |
What is being measured
The primary outcome is the main question the study is designed to answer.
IgG
Immunoglobulin-G (mg/dl)
Measured: at baseline and after one month
IgA
Immunoglobulin-A(mg/dl)
Measured: at baseline and after one month
IgM
Immunoglobulin-M (mg/dl)
Measured: at baseline and after one month
WBCs
White blood cells (thousands/mm3)
Measured: at baseline and after one month
Secondary outcomes (2)
RR
Respiratory Rate(breath/minute)
Measured: at baseline and after one month
SaO2
Arterial oxygen saturation(%)
Measured: at baseline and after one month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Apr 2026
- Study start6 Apr 2026
- Primary completion30 May 2026 (estimated)
- Study completion30 May 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for PneumoniaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Forty DS children with bronchopneumonia, mean age of 3.73±1.82 year and were included into 2 equal groups; group (A) received low intensity laser therapy, inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Badr University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mona Mohamed Abdelkhalek, Badr University
- Investigators
- Mona Mohamed Abdelkhalek, assistance prof, Principal investigator, Badr University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07552116
- Sponsor's protocol ID
- children with pneumonia
- Acronym
- intervention
- Status last verified
- Apr 2026
- First submitted
- 15 Apr 2026
- Last updated
- 27 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 27 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Impact of Low Intensity Laser Therapy on Immune System Response Among Children With Pneumonia
- ClinicalTrials.gov ID
- NCT07552116
- Acronym / sponsor ID
- intervention / children with pneumonia
- Conditions
- Pneumonia
- Keywords
- Laser, Immune, Pneumonia, Dawn syndrome
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Badr UniversityUniversity, hospital or other
- Study start
- 6 Apr 2026 (actual)
- Primary completion
- 30 May 2026 (estimated)
- Study completion
- 30 May 2026 (estimated)
- First posted
- 27 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Objective: The aim of this study was to detect the impact of low intensity laser therapy on immune system response among DS children with pneumonia. Material and Methods: Forty DS children with bronchopneumonia, were included into ; group (A) received low intensity laser therapy, inspiratory muscle training in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.
Detailed description
The aim of this study was to detect the impact of low intensity laser therapy on immune system response among DS children with pneumonia. Material and Methods: Forty DS children with bronchopneumonia, mean age of 3.73±1.82 year and were included into 2 equal groups; group (A) received low intensity laser therapy, inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- Forty DS children with bronchopneumonia, mean age of 3.73±1.82 year and were included into 2 equal groups; group (A) received low intensity laser therapy, inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.
| Arm | Type | Receives |
|---|---|---|
| group (A) | Experimental | Other: low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements, Other: received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.received low intensity laser therapy, inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment at a frequency of 3 sessions per week for one month |
| group (B) | Experimental | Other: received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. |
Who may qualify
- Ages
- 3 to 5 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (3 listed)
- Dawn Syndrome children with pneumonia
- Mean age of 3.73±1.82 year
- Children were in the first attack of bronchopneumonia.
Key exclusion criteria (1 listed)
- Other chest disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. MeasurementsAlso: low intensity laser therapy, muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurementslow intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements | Other | group (A) |
| received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.Also: inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. | Other | group (A), group (B) |
Primary outcome
IgG
Time frame: at baseline and after one month
Immunoglobulin-G (mg/dl)
IgA
Time frame: at baseline and after one month
Immunoglobulin-A(mg/dl)
IgM
Time frame: at baseline and after one month
Immunoglobulin-M (mg/dl)
WBCs
Time frame: at baseline and after one month
White blood cells (thousands/mm3)
2 secondary outcomes
RR
Time frame: at baseline and after one month
SaO2
Time frame: at baseline and after one month
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Apr 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Mona Mohamed Abdelkhalek, assistance prof principal investigator
Badr University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements and received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. in people with Pneumonia, run by Badr University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 27 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mona Mohamed Abdelkhalek, assistance professor (00201024056108, mona.abdelkhalek@buc.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
IgG (time frame: at baseline and after one month). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Apr 2026.