Parkinson Disease (PD)NCT07536542
Effects of Dual-Task Training on Upper Extremity Function in Parkinson's Disease
A study testing Dual-Task Training in people with Parkinson Disease (PD), run by Ankara University at 1 site in Turkey (Türkiye).
Trial summary
The goal of this clinical trial is to investigate the effects of dual-task training on upper extremity function and muscle thickness in individuals with Parkinson's disease. The main questions it aims to answer are: Does dual-task training improve upper extremity function in individuals with Parkinson's disease? Does… Read more about this study
- Who is it for?
- Ages 40 to 65 years
- Conditions the study is for
- Parkinson Disease (PD)
- What is being tested?
- Dual-Task Training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 38 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 24 Apr 2026to 1 Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Diagnosis of idiopathic Parkinson's disease confirmed by a neurologist
- Modified Hoehn and Yahr stage 2 to 3
- No medication or dosage change within the last 6 months
- Cognitive capacity sufficient to understand and follow instructions, defined as Montreal Cognitive Assessment score ≥21
- Voluntary participation with written informed consent
Who cannot join
- Atypical or secondary parkinsonism
- Advanced orthopedic condition affecting the upper extremity
- Surgery, trauma, or immobilization involving the upper extremity within the last 6 months
- Wound or dermatological condition preventing upper extremity ultrasonographic evaluation
- Severe visual or hearing loss
- Severe depression, psychosis, or communication difficulty
- Any additional health problem preventing regular participation in the study
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Hacettepe University
Ankara
Ayla Fil, Assoc.Prof. PhD, +905074708330, aylafil@gmail.com
About this study
Official title: Effects of Dual-Task Training on Upper Extremity Function and Muscle Thickness in Parkinson's Disease
The goal of this clinical trial is to investigate the effects of dual-task training on upper extremity function and muscle thickness in individuals with Parkinson's disease. The main questions it aims to answer are:
Does dual-task training improve upper extremity function in individuals with Parkinson's disease? Does dual-task training lead to changes in upper extremity muscle thickness measured by ultrasonography?
Read more
Researchers will compare a dual-task training group with a control group receiving routine care to determine whether 8 weeks of dual-task training results in greater improvements in upper extremity outco
Participants will:
complete baseline and post-intervention assessments of upper extremity function, muscle thickness, grip strength, and pinch strength be assigned to either a control group or a dual-task training group receive dual-task training 3 days per week for 8 weeks if assigned to the intervention group
- Conditions
- Parkinson Disease (PD)
- Being tested
- Dual-Task Training
- Keywords
- Parkinson Disease, Dual-Task Training, Upper Extremity Function, Muscle Thickness, Ultrasonography
- Medical subject headings
- Parkinson Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Dual-Task TrainingBehavioural
Dual-task training will be applied 3 times per week for 8 weeks, with each session lasting 60 minutes. The program combines motor tasks (such as peg placement, object manipulation, bilateral coordination, and mobility tasks) with simultaneous cognitive tasks (such as backward counting, category-based word generation, and memory tasks).
| Study group | Role | What they receive |
|---|---|---|
| Dual-Task Training Group | Experimental | Participants will receive dual-task training in addition to their routine daily activities. The training program will be performed 3 times per week for 8 weeks, with each session lasting 60 minutes and consisting of combined motor and cognitive tasks. Receives: Behavioral: Dual-Task Training |
| Control Group | No intervention | Participants will continue their routine daily activities without receiving any additional exercise, training, or rehabilitation intervention during the study period. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Upper Extremity Function
Upper extremity function will be assessed using the Purdue Pegboard Test. Performance will be recorded as the number of pins placed within the specified time for dominant hand, nondominant hand, and both hands; higher scores indicate better fine motor performance and manual dexterity.
Measured: Baseline and 8 weeks
Upper Extremity Muscle Thickness
Muscle thickness of the deltoid, biceps brachii, triceps brachii, and forearm flexor muscles will be measured using ultrasonography. The mean of three repeated measurements for each site will be recorded in millimeters.
Measured: Baseline and 8 weeks
Hand Grip Strength
Hand grip strength will be measured using a Jamar hydraulic hand dynamometer according to the ASHT protocol. The mean of three trials will be recorded.
Measured: Baseline and 8 weeks
Pinch Strength
Lateral pinch, three-jaw chuck pinch, and two-point pinch strength will be assessed using a pinch meter. The mean of three trials will be recorded in kilograms or Newtons.
Measured: Baseline and 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Apr 2026
- Study start24 Apr 2026
- Primary completion24 Jul 2026 (estimated)
- Study completion1 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Parkinson Disease (PD)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomly assigned to either a dual-task training group or a control group using block randomization. The dual-task training group will receive a structured exercise program consisting of combined motor and cognitive tasks, performed 3 times per week for 8 weeks, in addition to their usual daily activities. The control group will continue their routine daily life without receiving any additional intervention. Outcome assessments will be conducted at baseline and after 8 weeks by a blinded evaluator.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 38 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Ankara University
- Sponsor type
- University, hospital or other
- Collaborators
- Hacettepe University
- Responsible party
- Principal investigator, Büşra Seçkinoğulları Korkusuz, Ankara University
- Investigators
- Büşra Seçkinoğulları Korkusuz, Principal investigator, Ankara UniversitySüleyman Korkusuz, Study chair, Atılım UniversityAyşenur Özcan, Study chair, Çankırı Karatekin UniversityAyla Fil, Study chair, Hacettepe UniversityGül Yalçın Çakmaklı, Study chair, Hacettepe University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07536542
- Sponsor's protocol ID
- f57111e3114a4f65
- Status last verified
- Apr 2026
- First submitted
- 11 Apr 2026
- Last updated
- 2 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Dual-Task Training on Upper Extremity Function and Muscle Thickness in Parkinson's Disease
- ClinicalTrials.gov ID
- NCT07536542
- Acronym / sponsor ID
- f57111e3114a4f65
- Conditions
- Parkinson Disease (PD)
- Keywords
- Parkinson Disease, Dual-Task Training, Upper Extremity Function, Muscle Thickness, Ultrasonography
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 38 participants (estimated)
- Lead sponsor
- Ankara UniversityUniversity, hospital or other
- Collaborators
- Hacettepe University
- Study start
- 24 Apr 2026 (actual)
- Primary completion
- 24 Jul 2026 (estimated)
- Study completion
- 1 Aug 2026 (estimated)
- First posted
- 17 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to investigate the effects of dual-task training on upper extremity function and muscle thickness in individuals with Parkinson's disease. The main questions it aims to answer are:
Does dual-task training improve upper extremity function in individuals with Parkinson's disease? Does dual-task training lead to changes in upper extremity muscle thickness measured by ultrasonography?
Researchers will compare a dual-task training group with a control group receiving routine care to determine whether 8 weeks of dual-task training results in greater improvements in upper extremity outco
Participants will:
complete baseline and post-intervention assessments of upper extremity function, muscle thickness, grip strength, and pinch strength be assigned to either a control group or a dual-task training group receive dual-task training 3 days per week for 8 weeks if assigned to the intervention group
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- Participants will be randomly assigned to either a dual-task training group or a control group using block randomization. The dual-task training group will receive a structured exercise program consisting of combined motor and cognitive tasks, performed 3 times per week for 8 weeks, in addition to their usual daily activities. The control group will continue their routine daily life without receiving any additional intervention. Outcome assessments will be conducted at baseline and after 8 weeks by a blinded evaluator.
| Arm | Type | Receives |
|---|---|---|
| Dual-Task Training Group | Experimental | Behavioral: Dual-Task TrainingParticipants will receive dual-task training in addition to their routine daily activities. The training program will be performed 3 times per week for 8 weeks, with each session lasting 60 minutes and consisting of combined motor and cognitive tasks. |
| Control Group | No intervention | –Participants will continue their routine daily activities without receiving any additional exercise, training, or rehabilitation intervention during the study period. |
Who may qualify
- Ages
- 40 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Diagnosis of idiopathic Parkinson's disease confirmed by a neurologist
- Modified Hoehn and Yahr stage 2 to 3
- No medication or dosage change within the last 6 months
- Cognitive capacity sufficient to understand and follow instructions, defined as Montreal Cognitive Assessment score ≥21
- Voluntary participation with written informed consent
Key exclusion criteria (7 listed)
- Atypical or secondary parkinsonism
- Advanced orthopedic condition affecting the upper extremity
- Surgery, trauma, or immobilization involving the upper extremity within the last 6 months
- Wound or dermatological condition preventing upper extremity ultrasonographic evaluation
- Severe visual or hearing loss
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Dual-Task TrainingDual-task training will be applied 3 times per week for 8 weeks, with each session lasting 60 minutes. The program combines motor tasks (such as peg placement, object manipulation, bilateral coordination, and mobility tasks) with simultaneous cognitive tasks (such as backward counting, category-based word generation, and memory tasks). | Behavioural | Dual-Task Training Group |
Primary outcome
Upper Extremity Function
Time frame: Baseline and 8 weeks
Upper extremity function will be assessed using the Purdue Pegboard Test. Performance will be recorded as the number of pins placed within the specified time for dominant hand, nondominant hand, and both hands; higher scores indicate better fine motor performance and manual dexterity.
Upper Extremity Muscle Thickness
Time frame: Baseline and 8 weeks
Muscle thickness of the deltoid, biceps brachii, triceps brachii, and forearm flexor muscles will be measured using ultrasonography. The mean of three repeated measurements for each site will be recorded in millimeters.
Hand Grip Strength
Time frame: Baseline and 8 weeks
Hand grip strength will be measured using a Jamar hydraulic hand dynamometer according to the ASHT protocol. The mean of three trials will be recorded.
Pinch Strength
Time frame: Baseline and 8 weeks
Lateral pinch, three-jaw chuck pinch, and two-point pinch strength will be assessed using a pinch meter. The mean of three trials will be recorded in kilograms or Newtons.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Büşra Seçkinoğulları Korkusuz principal investigator
Ankara University
Süleyman Korkusuz study chair
Atılım University
Ayşenur Özcan study chair
Çankırı Karatekin University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Dual-Task Training in people with Parkinson Disease (PD), run by Ankara University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 2 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Büşra Seçkinoğulları Korkusuz, PhD (+905442436914, bskorkusuz@ankara.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Upper Extremity Function (time frame: Baseline and 8 weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Jun 2026.