Dry Eye Disease (DED)NCT07525336
Effect of Dry Eye Disease on Accuracy of Intraocular Lens Power Calculation Before Phacoemulsification
An observational study of Dry Eye Disease (DED) and Cataract (Post-operative Cataract Surgery Follow-up), run by Assiut University.
Trial summary
This study aims to determine the effect of dry eye disease on intraocular lens power calculation and the postoperative refractive outcome. Read more about this study
- Who is it for?
- Ages 40 years and older
- Conditions the study is for
- Dry Eye Disease (DED), Cataract (Post-operative Cataract Surgery Follow-up)
- What is being tested?
- dry eye disease optimization
- Type of treatment
- Surgery or procedure
- How many people
- 100 participants
- Where
- No sites listed yet
- Study dates
- 30 Apr 2026to 30 Apr 2029
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: The study population will consist of adult patients aged 40 years and older diagnosed with cataract and scheduled for phacoemulsification surgery at Assiut University Hospital.
Who may be able to join
- Age equals to or above 40 years old
- cataract patient
- suitable for phacoemulsification
- clear corneal media
Who cannot join
- previous corneal surgery
- advanced glaucoma
- corneal pathology (keratoconus, scarring)
- retinal disease affecting vision
- irregular astigmatism
- contact lens use within the last 2 weeks
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
This study aims to determine the effect of dry eye disease on intraocular lens power calculation and the postoperative refractive outcome.
- Being tested
- dry eye disease optimization
- Keywords
- dry eye disease, biometry, refractive surprise, phacoemulsification
- Medical subject headings
- Dry Eye Syndromes, Cataract
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
dry eye disease optimizationProcedure or surgery
dry eye disease management prior to obtaining intraocular lens power calculation
| Study group | Role | What they receive |
|---|---|---|
| dry eye disease | dry eye disease patients who are not optimized before phacoemulsification | |
| non dry eye disease | non dry eye disease patients before phacoemulsification Receives: Procedure: dry eye disease optimization |
What is being measured
The primary outcome is the main question the study is designed to answer.
Compare mean absolute error (MAE) between patients with and without DED
Measured: 2 yeras
Compare mean absolute error (MAE) between patients with and without DED
Measured: 2 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Apr 2026
- Study start30 Apr 2026 (estimated)
- Primary completion30 Apr 2028 (estimated)
- Study completion30 Apr 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Dry Eye Disease (DED)Studies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ziad Mohamed Abdelaal Sayed, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07525336
- Sponsor's protocol ID
- DED IOL power calculation
- Status last verified
- Apr 2026
- First submitted
- 7 Apr 2026
- Last updated
- 13 Apr 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 13 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Dry Eye Disease on Accuracy of Intraocular Lens Power Calculation Before Phacoemulsification
- ClinicalTrials.gov ID
- NCT07525336
- Acronym / sponsor ID
- DED IOL power calculation
- Keywords
- dry eye disease, biometry, refractive surprise, phacoemulsification
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- 30 Apr 2026 (estimated)
- Primary completion
- 30 Apr 2028 (estimated)
- Study completion
- 30 Apr 2029 (estimated)
- First posted
- 13 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to determine the effect of dry eye disease on intraocular lens power calculation and the postoperative refractive outcome.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| dry eye disease | – | –dry eye disease patients who are not optimized before phacoemulsification |
| non dry eye disease | – | Procedure: dry eye disease optimizationnon dry eye disease patients before phacoemulsification |
Who may qualify
- Ages
- 40 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- The study population will consist of adult patients aged 40 years and older diagnosed with cataract and scheduled for phacoemulsification surgery at Assiut University Hospital.
Key inclusion criteria (4 listed)
- Age equals to or above 40 years old
- cataract patient
- suitable for phacoemulsification
- clear corneal media
Key exclusion criteria (6 listed)
- previous corneal surgery
- advanced glaucoma
- corneal pathology (keratoconus, scarring)
- retinal disease affecting vision
- irregular astigmatism
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| dry eye disease optimizationdry eye disease management prior to obtaining intraocular lens power calculation | Procedure or surgery | non dry eye disease |
Primary outcome
Compare mean absolute error (MAE) between patients with and without DED
Time frame: 2 yeras
Compare mean absolute error (MAE) between patients with and without DED
Time frame: 2 years
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Apr 2026.
- Individual participant dataSharing planned: Undecided
Related trials for Dry Eye Disease (DED)
Not yet recruitingPhase 2
Evaluation of Allogenic Mesenchymal Stem Cell (MSC) Injection Therapy for Refractory Graft-versus-Host Disease (GVHD) Unresponsive to Conventional Treatments
Dry Eye Disease (DED), Graft-Versus-Host Disease(GVHD)
Not yet recruitingEarly Phase 1
a Novel siRNA Eyedrops for DED Treatment
Dry Eye
Active, not recruiting
Clinical Study Evaluating Nordlys™ SWT IPL for Dry Eye Disease (DED) Due to MGD
Meibomian Gland Dysfunction, Dry Eye Disease
Recruiting
Treating Contact Lens Discomfort With Cyclosporine 0.1% Ophthalmic Solution
Dry Eye Disease (DED), Contact Lens Discomfort (CLD)
Not yet recruitingPhase 1
A Clinical Study to Evaluate the Safety and Effectiveness of MSCohi-O Lens in the Treatment of Immune-related Ocular Surface Diseases.
Keratitis, Autoimmunity
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
An observational study of Dry Eye Disease (DED) and Cataract (Post-operative Cataract Surgery Follow-up), run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 13 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ziad M.A Sayed (+201152373413, mkkh30@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Compare mean absolute error (MAE) between patients with and without DED (time frame: 2 yeras). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Apr 2026.