Psychogenic Nonepileptic SeizuresNCT07521761
Video-EEG Features of Adult Patients With Psychogenic Nonepileptic Seizures
An observational study of Psychogenic Nonepileptic Seizures, run by Saglik Bilimleri Universitesi at 1 site in Turkey (Türkiye).
Trial summary
This completed retrospective observational study evaluated adult patients diagnosed with psychogenic nonepileptic seizures (PNES) who underwent video-EEG monitoring. Video-EEG records and clinical data of 50 adult patients were reviewed to describe semiological, electroclinical, and demographic characteristics of… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Psychogenic Nonepileptic Seizures
- How many people
- 50 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jan 2026to 1 Mar 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adult patients diagnosed with psychogenic nonepileptic seizures (PNES) who underwent video-EEG monitoring.
Who may be able to join
- Adults aged 18 years and older
- Diagnosis of psychogenic nonepileptic seizures based on video-EEG evaluation
- Availability of complete video-EEG recordings and relevant clinical records for review
Who cannot join
- Patients younger than 18 years
- Inadequate or incomplete video-EEG data
- Patients with insufficient clinical documentation for retrospective evaluation
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Saglik Bilimleri University Izmir Faculty of Medicine Department of Neurology
Izmir
About this study
Official title: Retrospective Analysis of Video-EEG Findings and Clinical Characteristics in Adult Patients With Psychogenic Nonepileptic Seizures
This completed retrospective observational study evaluated adult patients diagnosed with psychogenic nonepileptic seizures (PNES) who underwent video-EEG monitoring. Video-EEG records and clinical data of 50 adult patients were reviewed to describe semiological, electroclinical, and demographic characteristics of PNES. The study aimed to improve the understanding of video-EEG findings in PNES and to support accurate diagnosis in clinical practice.
Read the detailed description
Psychogenic nonepileptic seizures (PNES) are paroxysmal events that resemble epileptic seizures but are not associated with ictal epileptiform activity on EEG. Video-EEG monitoring is considered the reference standard for diagnosis. In this retrospective observational study, video-EEG recordings and clinical files of 50 adult patients with PNES were reviewed after completion of clinical care. Demographic data, clinical presentation, and video-EEG characteristics were analyzed descriptively. No intervention was assigned as part of the study. The purpose was to characterize the video-EEG and clinical profile of adult PNES patients evaluated in routine practice.
- Conditions
- Psychogenic Nonepileptic Seizures
- Medical subject headings
- Psychogenic Nonepileptic Seizures
What is being measured
The primary outcome is the main question the study is designed to answer.
Semiological subtype of PNES events
Classification of PNES events recorded during video-EEG monitoring into semiological clusters (pauci-kinetic, hyperkinetic, hyperventilation-eye closure) based on ictal features.
Measured: Baseline retrospective chart and video-EEG review
Secondary outcomes (1)
Presence/absence of some events during PNES events
Eye closure during PNES events Hyperventilation during PNES events Hyperkinetic motor activity Axial extension Pelvic thrusting
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Apr 2026
- Study start1 Jan 2026
- Primary completion1 Mar 2026
- Study completion1 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Psychogenic Nonepileptic SeizuresStudies of the same condition, open and under way.
- More trials run by Saglik Bilimleri UniversitesiThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Retrospective
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Saglik Bilimleri Universitesi
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07521761
- Sponsor's protocol ID
- 2026/02-17
- Status last verified
- Mar 2026
- First submitted
- 10 Mar 2026
- Last updated
- 13 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 13 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Retrospective Analysis of Video-EEG Findings and Clinical Characteristics in Adult Patients With Psychogenic Nonepileptic Seizures
- ClinicalTrials.gov ID
- NCT07521761
- Acronym / sponsor ID
- 2026/02-17
- Conditions
- Psychogenic Nonepileptic Seizures
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Saglik Bilimleri UniversitesiUniversity, hospital or other
- Study start
- 1 Jan 2026 (actual)
- Primary completion
- 1 Mar 2026 (actual)
- Study completion
- 1 Mar 2026 (actual)
- First posted
- 13 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This completed retrospective observational study evaluated adult patients diagnosed with psychogenic nonepileptic seizures (PNES) who underwent video-EEG monitoring. Video-EEG records and clinical data of 50 adult patients were reviewed to describe semiological, electroclinical, and demographic characteristics of PNES. The study aimed to improve the understanding of video-EEG findings in PNES and to support accurate diagnosis in clinical practice.
Detailed description
Psychogenic nonepileptic seizures (PNES) are paroxysmal events that resemble epileptic seizures but are not associated with ictal epileptiform activity on EEG. Video-EEG monitoring is considered the reference standard for diagnosis. In this retrospective observational study, video-EEG recordings and clinical files of 50 adult patients with PNES were reviewed after completion of clinical care. Demographic data, clinical presentation, and video-EEG characteristics were analyzed descriptively. No intervention was assigned as part of the study. The purpose was to characterize the video-EEG and clinical profile of adult PNES patients evaluated in routine practice.
Study design
- Observational model
- Case only
- Time perspective
- Retrospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adult patients diagnosed with psychogenic nonepileptic seizures (PNES) who underwent video-EEG monitoring.
Key inclusion criteria (3 listed)
- Adults aged 18 years and older
- Diagnosis of psychogenic nonepileptic seizures based on video-EEG evaluation
- Availability of complete video-EEG recordings and relevant clinical records for review
Key exclusion criteria (3 listed)
- Patients younger than 18 years
- Inadequate or incomplete video-EEG data
- Patients with insufficient clinical documentation for retrospective evaluation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Semiological subtype of PNES events
Time frame: Baseline retrospective chart and video-EEG review
Classification of PNES events recorded during video-EEG monitoring into semiological clusters (pauci-kinetic, hyperkinetic, hyperventilation-eye closure) based on ictal features.
1 secondary outcome
Presence/absence of some events during PNES events
Time frame: Baseline
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Apr 2026.
Related trials for Psychogenic Nonepileptic Seizures
RecruitingEarly Phase 1
Accelerated TMS for Seizure-Type Functional Neurologic Disorders
Functional Neurological Symptom Disorder, Functional Seizures
Recruiting
Modulating Movement Intention Via Cortical Stimulation
Seizures, Seizure Disorder
Recruiting
Retraining and Control Therapy (ReACT): Sense of Control and Symptom Expectations as Targets of a Treatment for PNES
Convulsion, Non-Epileptic
RecruitingPhase 1/2
Effects of a Sigle Dose of Ayahuasca in Patients With Psychogenic Non-epileptic Seizures: an Open Label Clinical Trial
Non Epileptic Seizures
Active, not recruitingObservational study
Study on the Rapid Diagnostic Value of Sudden Clap Provocation Test in Psychogenic Nonepileptic Seizures
Epilepsy, Psychogenic Non-epileptic Seizures
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Psychogenic Nonepileptic Seizures, run by Saglik Bilimleri Universitesi at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 13 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Semiological subtype of PNES events (time frame: Baseline retrospective chart and video-EEG review). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Apr 2026.