Sore ThroatNCT07517926
Chewing Gum and Cold Gargle on Post-Bronchoscopy Symptoms
A study testing Chewing Gum and Cold Water Gargle in people with Sore Throat and Dysphagia, run by Ankara University at 1 site in Turkey (Türkiye).
Trial summary
This study aims to evaluate the effects of chewing gum and gargling with cold water on common post-bronchoscopy symptoms, such as sore throat and difficulty swallowing (dysphagia). Bronchoscopy is a procedure that can cause temporary throat discomfort. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Sore Throat, Dysphagia, Patient Satisfaction
- What is being tested?
- Chewing Gum and Cold Water Gargle
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 108 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Sep 2025to 27 Feb 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Being 18 years of age or older Being scheduled for a non-emergency bronchoscopy Having normal speech and swallowing functions Being conscious and able to communicate Agreeing to participate and providing written informed consent Exclusion Criteria
- Gastroesophageal reflux Signs of active infection in the oral or throat region Use of non-steroidal anti-inflammatory drugs (NSAIDs) Any drug allergy Steroid therapy during the week before the procedure Anatomical or functional impairment that prevents chewing gum or gargling Undergoing emergency interventional bronchoscopy
Who cannot join
None listed.
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Gulhane Training and Research Hospital
Ankara, Ankara, 06010
About this study
Official title: The Effect of Chewing Gum and Cold Water Gargle Intervention on Post-Bronchoscopy Sore Throat, Dysphagia, and Patient Satisfaction: A Randomized Controlled Trial
This study aims to evaluate the effects of chewing gum and gargling with cold water on common post-bronchoscopy symptoms, such as sore throat and difficulty swallowing (dysphagia). Bronchoscopy is a procedure that can cause temporary throat discomfort. In this randomized controlled trial, patients will be divided into groups to receive either chewing gum, cold water gargle, or standard care. The researchers will then measure and compare patient satisfaction levels and the severity of throat symptoms to determine if these simple interventions can improve patient comfort after the procedure.
Read the detailed description
Study Implementation and Procedures
All patients in the intervention and control groups will be informed about the study's purpose. Patients undergoing bronchoscopy receive routine verbal education from bronchoscopy nurses. In addition to routine education, the intervention groups will receive specific instructions from the researchers. Patients will be blinded to their randomization status and study hypotheses. However, researchers will not be blinded as they will perform the interventions. The chewing gum and cold water gargle procedures will be explained and demonstrated to the intervention groups during face-to-face interviews.
Chewing Gum Procedure All patients will follow the hospital's standard pre-procedure fasting protocol (8 hours of fasting). A researcher will be responsible for supervising the chewing gum procedure. Patients in this group will be asked to chew a commercially available sugar-free gum containing xylitol for 15 minutes immediately before the procedure. After 15 minutes of chewing, patients will discard the gum. The researcher will ensure the gum is removed before the patient is admitted for bronchoscopy. Patients will be strictly instructed not to swallow the gum.
Cold Water Gargle Procedure Patients in this group will perform a cold water gargle under the supervision of a researcher 15 minutes before the procedure. Patients will be instructed not to swallow the water. The researcher will prepare the water at a temperature between 8-12°C (refrigerator coldness). Patients will gargle twice for 30 seconds each, approximately 15 minutes before the procedure.
Control Group The control group will receive standard hospital procedures without any additional intervention.
Data Collection and Evaluation Sore throat, difficulty swallowing (dysphagia), and patient satisfaction levels will be evaluated before the procedure, and at the 2nd and 24th hours post-procedure. The 24-hour evaluation will be conducted via telephone by the research team.
- Conditions
- Sore Throat, Dysphagia, Patient Satisfaction, Bronchoscopy
- Being tested
- Chewing Gum, Cold Water Gargle
- Keywords
- Bronchoscopy, Sore Throat, Dysphagia, Chewing Gum, Cold Water Gargle, Nursing Care
- Medical subject headings
- Pharyngitis, Deglutition Disorders, Patient Satisfaction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Chewing GumBehavioural
Patients will chew sugar-free xylitol gum for 15 minutes immediately before the bronchoscopy procedure
Cold Water GargleBehavioural
Patients will gargle with cold water (8-12°C) twice for 30 seconds each, 15 minutes before the bronchoscopy procedure.
| Study group | Role | What they receive |
|---|---|---|
| Chewing Gum Group | Experimental | Patients in this group will chew sugar-free xylitol gum for 15 minutes immediately before bronchoscopy. Receives: Behavioral: Chewing Gum |
| Cold Water Gargle Group | Experimental | Patients in this group will gargle with cold water (8-12°C) twice for 30 seconds each, 15 minutes before bronchoscopy. Receives: Behavioral: Cold Water Gargle |
| Control Group | No intervention | Patients in this group will receive standard care without additional interventions. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Severity of Post-Bronchoscopy Sore Throat
Sore throat severity was assessed using a Visual Analog Scale (VAS), where 0 represents "no pain" and 10 represents "very severe pain." Higher scores indicate greater pain severity.
Measured: Baseline (pre-procedure), 2nd hour, and 24th hour post-procedure.
Secondary outcomes (2)
Severity of Post-Bronchoscopy Dysphagia
Dysphagia severity was assessed using the Eating Assessment Tool-10 (EAT-10), a 10-item scale with total scores ranging from 0 to 40. Higher scores indicate more severe dysphagia; a score of 3 or higher is considered abnormal.
Measured: Baseline (pre-procedure), 2nd hour, and 24th hour post-procedure.
Patient Satisfaction Level
Patient satisfaction was assessed using the Patient Satisfaction Questionnaire Short Form (PSQ-18), which includes seven subscales: general satisfaction, technical quality, interpersonal manner, communication, financial aspects, time spent with the doctor, and accessibility and convenience.
Measured: Before bronchoscopy and 24 hours after the procedure.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Apr 2026
- Study start15 Sep 2025
- Primary completion20 Feb 2026
- Study completion27 Feb 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Sore ThroatStudies of the same condition, open and under way.
- More trials run by Ankara UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- This is a three-arm, randomized, parallel-group study comparing two interventions (chewing gum and cold water gargle) with a standard care control group
- Masking
- None (open label)
- Enrolment
- 108 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ankara University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Neriman Yükseltürk Simşek, Ankara University
- Investigators
- neriman yükseltürk şimşek, Principal investigator, ankara u
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07517926
- Sponsor's protocol ID
- 2025/177
- Status last verified
- Oct 2026
- First submitted
- 2 Apr 2026
- Last updated
- 23 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared to protect participant privacy and confidentiality.
Study at a glance
From the registry record, last updated by the sponsor on 23 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Chewing Gum and Cold Water Gargle Intervention on Post-Bronchoscopy Sore Throat, Dysphagia, and Patient Satisfaction: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07517926
- Acronym / sponsor ID
- 2025/177
- Conditions
- Sore Throat, Dysphagia, Patient Satisfaction, Bronchoscopy
- Keywords
- Bronchoscopy, Sore Throat, Dysphagia, Chewing Gum, Cold Water Gargle, Nursing Care
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 108 participants (actual)
- Lead sponsor
- Ankara UniversityUniversity, hospital or other
- Study start
- 15 Sep 2025 (actual)
- Primary completion
- 20 Feb 2026 (actual)
- Study completion
- 27 Feb 2026 (actual)
- First posted
- 8 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate the effects of chewing gum and gargling with cold water on common post-bronchoscopy symptoms, such as sore throat and difficulty swallowing (dysphagia). Bronchoscopy is a procedure that can cause temporary throat discomfort. In this randomized controlled trial, patients will be divided into groups to receive either chewing gum, cold water gargle, or standard care. The researchers will then measure and compare patient satisfaction levels and the severity of throat symptoms to determine if these simple interventions can improve patient comfort after the procedure.
Detailed description
Study Implementation and Procedures
All patients in the intervention and control groups will be informed about the study's purpose. Patients undergoing bronchoscopy receive routine verbal education from bronchoscopy nurses. In addition to routine education, the intervention groups will receive specific instructions from the researchers. Patients will be blinded to their randomization status and study hypotheses. However, researchers will not be blinded as they will perform the interventions. The chewing gum and cold water gargle procedures will be explained and demonstrated to the intervention groups during face-to-face interviews.
Chewing Gum Procedure All patients will follow the hospital's standard pre-procedure fasting protocol (8 hours of fasting). A researcher will be responsible for supervising the chewing gum procedure. Patients in this group will be asked to chew a commercially available sugar-free gum containing xylitol for 15 minutes immediately before the procedure. After 15 minutes of chewing, patients will discard the gum. The researcher will ensure the gum is removed before the patient is admitted for bronchoscopy. Patients will be strictly instructed not to swallow the gum.
Cold Water Gargle Procedure Patients in this group will perform a cold water gargle under the supervision of a researcher 15 minutes before the procedure. Patients will be instructed not to swallow the water. The researcher will prepare the water at a temperature between 8-12°C (refrigerator coldness). Patients will gargle twice for 30 seconds each, approximately 15 minutes before the procedure.
Control Group The control group will receive standard hospital procedures without any additional intervention.
Data Collection and Evaluation Sore throat, difficulty swallowing (dysphagia), and patient satisfaction levels will be evaluated before the procedure, and at the 2nd and 24th hours post-procedure. The 24-hour evaluation will be conducted via telephone by the research team.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
- Model description
- This is a three-arm, randomized, parallel-group study comparing two interventions (chewing gum and cold water gargle) with a standard care control group
| Arm | Type | Receives |
|---|---|---|
| Chewing Gum Group | Experimental | Behavioral: Chewing GumPatients in this group will chew sugar-free xylitol gum for 15 minutes immediately before bronchoscopy. |
| Cold Water Gargle Group | Experimental | Behavioral: Cold Water GarglePatients in this group will gargle with cold water (8-12°C) twice for 30 seconds each, 15 minutes before bronchoscopy. |
| Control Group | No intervention | –Patients in this group will receive standard care without additional interventions. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Being 18 years of age or older Being scheduled for a non-emergency bronchoscopy Having normal speech and swallowing functions Being conscious and able to communicate Agreeing to participate and providing written informed consent Exclusion Criteria
- Gastroesophageal reflux Signs of active infection in the oral or throat region Use of non-steroidal anti-inflammatory drugs (NSAIDs) Any drug allergy Steroid therapy during the week before the procedure Anatomical or functional impairment that prevents chewing gum or gargling Undergoing emergency interventional bronchoscopy
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Chewing GumPatients will chew sugar-free xylitol gum for 15 minutes immediately before the bronchoscopy procedure | Behavioural | Chewing Gum Group |
| Cold Water GarglePatients will gargle with cold water (8-12°C) twice for 30 seconds each, 15 minutes before the bronchoscopy procedure. | Behavioural | Cold Water Gargle Group |
Primary outcome
Severity of Post-Bronchoscopy Sore Throat
Time frame: Baseline (pre-procedure), 2nd hour, and 24th hour post-procedure.
Sore throat severity was assessed using a Visual Analog Scale (VAS), where 0 represents "no pain" and 10 represents "very severe pain." Higher scores indicate greater pain severity.
2 secondary outcomes
Severity of Post-Bronchoscopy Dysphagia
Time frame: Baseline (pre-procedure), 2nd hour, and 24th hour post-procedure.
Patient Satisfaction Level
Time frame: Before bronchoscopy and 24 hours after the procedure.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Oct 2026.
- Individual participant dataSharing planned: No. Individual participant data will not be shared to protect participant privacy and confidentiality.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
neriman yükseltürk şimşek principal investigator
ankara u
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Chewing Gum and Cold Water Gargle in people with Sore Throat and Dysphagia, run by Ankara University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Severity of Post-Bronchoscopy Sore Throat (time frame: Baseline (pre-procedure), 2nd hour, and 24th hour post-procedure.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Oct 2026.