Colorectal DisordersNCT07517848
Comparison of the Left-Lateral Horizontal and Supine Positions for Colonoscopy Intervention: A Randomized Controlled Study
A study testing Colonoscopy after bowel cleansing in people with Colorectal Disorders and Colorectal Neoplasms, run by Manisa Celal Bayar University at 1 site in Turkey (Türkiye).
Trial summary
Objective: One of the most common technical difficulties during colonoscopy is passing through the fold of the sigmoid colon. Colonoscopy is commonly performed by endoscopists with the patient in the left lateral position. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Colorectal Disorders, Colorectal Neoplasms, Colorectal Polyp
- What is being tested?
- Colonoscopy after bowel cleansing
- Type of treatment
- Medical device, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 198 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Feb 2021to 15 Aug 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Female and male patients over 18 years of age who have been medically indicated for colonoscopy and have signed the voluntary consent form.
Who cannot join
- Patients under 18 years of age
- Patients who do not give informed consent
- Pregnant women
- Patients requesting sedation
- Patients with an indication for emergency colonoscopy
- Patients with a history of colon resection
- Major psychiatric disorders
Trial locations and contacts
1 site in 1 country.
About this study
Objective: One of the most common technical difficulties during colonoscopy is passing through the fold of the sigmoid colon. Colonoscopy is commonly performed by endoscopists with the patient in the left lateral position. When the procedure is initiated in the left lateral position, insufflation of the bowel may result in a sharper angulation of the sigmoid colon, making advancement of the colonoscope more difficult. This study aimed to compare colonoscopic procedures initiated in the left lateral position and the supine position.
Materials and Methods: Colonoscopy was performed on 198 participants who had an indication for colonoscopy at the General Surgery clinic and met the study inclusion criteria. All procedures were conducted by the same endoscopist (Dr. Semra Tutcu Şahin) in the Endoscopy Unit during working hours. Participants were randomly assigned to two groups:
Read more
Group 1: Participants whose starting position for colonoscopy was supine (n=97) Group 2: Participants whose starting position for colonoscopy was left lateral (n=101)
During colonoscopy, participants' demographic data, vital signs, and the time required for the endoscopist to reach the cecum were recorded. At the end of the procedure, participants completed a pain scale, and the endoscopist completed an observation scale. The data were entered into the SPSS program and analyzed.
Read the detailed description
Objective: One of the most common technical difficulties during colonoscopy is passing through the fold of the sigmoid colon. Colonoscopy is commonly performed by endoscopists with the patient in the left lateral position. When the procedure is initiated in the left lateral position, insufflation of the bowel may result in a sharper angulation of the sigmoid colon, making advancement of the colonoscope more difficult. This study aimed to compare colonoscopic procedures initiated in the left lateral position and the supine position.
Materials and Methods: Colonoscopy was performed on 198 participants who had an indication for colonoscopy at the General Surgery clinic and met the study inclusion criteria. All procedures were conducted by the same endoscopist (Dr. Semra Tutcu Şahin) in the Endoscopy Unit during working hours. Participants were randomly assigned to two groups:
Group 1: Participants whose starting position for colonoscopy was supine (n=97) Group 2: Participants whose starting position for colonoscopy was left lateral (n=101)
During colonoscopy, participants' demographic data, vital signs, and the time required for the endoscopist to reach the cecum were recorded. At the end of the procedure, participants completed a pain scale, and the endoscopist completed an observation scale. The data were entered into the SPSS program and analyzed.
- Being tested
- Colonoscopy after bowel cleansing
- Keywords
- colonoscopy, endoscopy, colorectal cancer, colon polyps
- Medical subject headings
- Colorectal Neoplasms, Colonic Neoplasms, Colonic Polyps
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Colonoscopy after bowel cleansingProcedure or surgery
Colonoscopy after bowel cleansing
Colonoscopy after bowel cleansingDevice
COLONOSCOPY WITH LEFT LATERAL AND SUPINE POSITION
| Study group | Role | What they receive |
|---|---|---|
| Supine position (SP) | Other | The first group consisted of patients assigned to the supine position (SP) as the initial position for colonoscopy Receives: Procedure: Colonoscopy after bowel cleansing; Device: Colonoscopy after bowel cleansing |
| Lateral Left Horizontal Position (LLP) | Other | The second group consisted of patients assigned to the left lateral horizontal position (LLP) as the initial position for colonoscopy Receives: Procedure: Colonoscopy after bowel cleansing; Device: Colonoscopy after bowel cleansing |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cecal intubation time
Time (in seconds) from insertion of the colonoscope at the anal verge to successful cecal intubation, defined by visualization of the appendiceal orifice and ileocecal valve, recorded by the endoscopist.
Measured: During the colonoscopy procedure
Secondary outcomes (3)
Pain score during colonoscopy
Pain intensity assessed immediately after the procedure using a 10-point Visual Analog Scale (VASP), where 0 indicates no pain and 10 indicates worst imaginable pain.
Measured: Immediately after colonoscopy
Endoscopist-rated procedure difficulty
Procedure difficulty assessed immediately after colonoscopy using a 4-point Likert scale (1 = very easy, 2 = easy, 3 = difficult, 4 = very difficult), as rated by the endoscopist.
Measured: Immediately after colonoscopy
Changes in vital signs during colonoscopy
Heart rate (beats per minute) measured at baseline and at 5-minute intervals during the procedure. The maximum change from baseline will be recorded.
Measured: During the colonoscopy procedure
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Apr 2026
- Study start1 Feb 2021
- Primary completion1 Oct 2023
- Study completion15 Aug 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Colorectal DisordersStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 198 participants (actual)
Sponsor and investigators
- Lead sponsor
- Manisa Celal Bayar University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07517848
- Sponsor's protocol ID
- CelalBayarU
- Status last verified
- Apr 2026
- First submitted
- 6 Dec 2025
- Last updated
- 8 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Anonymized study results
Publications
McKechnie T, Heimann L, Kazi T, Jessani G, Lee Y, Sne N, Hong D, Eskicioglu C. Starting position during colonoscopy: a systematic review and meta-analysis of randomized controlled trials. Tech Coloproctol. 2024 Mar 20;28(1):39. doi: 10.1007/s10151-024-02912-8.
PubMed 38507105Ramai D, Singh J, Brooks OW, Barakat M, Mohan BP, Chandan S, Khan SR, Dhindsa B, Dhaliwal A, Ofosu A, Adler DG. Comparison of left versus right lateral starting position on colonoscopy: a systematic review and meta-analysis of randomized controlled trials. Ann Gastroenterol. 2021 Sep-Oct;34(5):699-704. doi: 10.20524/aog.2021.0639. Epub 2021 Jun 3.
PubMed 34475741Watanabe J, Park D, Kakehi E, Inoue K, Ishikawa S, Kataoka Y. Efficacy and safety of the starting position during colonoscopy: a systematic review and meta-analysis. Endosc Int Open. 2020 Jul;8(7):E848-E860. doi: 10.1055/a-1149-1541. Epub 2020 Jun 16.
PubMed 32617389Li N, Lu B, Luo C, Cai J, Lu M, Zhang Y, Chen H, Dai M. Incidence, mortality, survival, risk factor and screening of colorectal cancer: A comparison among China, Europe, and northern America. Cancer Lett. 2021 Dec 1;522:255-268. doi: 10.1016/j.canlet.2021.09.034. Epub 2021 Sep 24.
PubMed 34563640
Study at a glance
From the registry record, last updated by the sponsor on 8 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Left-Lateral Horizontal and Supine Positions for Colonoscopy Intervention: A Randomized Controlled Study
- ClinicalTrials.gov ID
- NCT07517848
- Acronym / sponsor ID
- CelalBayarU
- Keywords
- colonoscopy, endoscopy, colorectal cancer, colon polyps
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 198 participants (actual)
- Lead sponsor
- Manisa Celal Bayar UniversityUniversity, hospital or other
- Study start
- 1 Feb 2021 (actual)
- Primary completion
- 1 Oct 2023 (actual)
- Study completion
- 15 Aug 2024 (actual)
- First posted
- 8 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Objective: One of the most common technical difficulties during colonoscopy is passing through the fold of the sigmoid colon. Colonoscopy is commonly performed by endoscopists with the patient in the left lateral position. When the procedure is initiated in the left lateral position, insufflation of the bowel may result in a sharper angulation of the sigmoid colon, making advancement of the colonoscope more difficult. This study aimed to compare colonoscopic procedures initiated in the left lateral position and the supine position.
Materials and Methods: Colonoscopy was performed on 198 participants who had an indication for colonoscopy at the General Surgery clinic and met the study inclusion criteria. All procedures were conducted by the same endoscopist (Dr. Semra Tutcu Şahin) in the Endoscopy Unit during working hours. Participants were randomly assigned to two groups:
Group 1: Participants whose starting position for colonoscopy was supine (n=97) Group 2: Participants whose starting position for colonoscopy was left lateral (n=101)
During colonoscopy, participants' demographic data, vital signs, and the time required for the endoscopist to reach the cecum were recorded. At the end of the procedure, participants completed a pain scale, and the endoscopist completed an observation scale. The data were entered into the SPSS program and analyzed.
Detailed description
Objective: One of the most common technical difficulties during colonoscopy is passing through the fold of the sigmoid colon. Colonoscopy is commonly performed by endoscopists with the patient in the left lateral position. When the procedure is initiated in the left lateral position, insufflation of the bowel may result in a sharper angulation of the sigmoid colon, making advancement of the colonoscope more difficult. This study aimed to compare colonoscopic procedures initiated in the left lateral position and the supine position.
Materials and Methods: Colonoscopy was performed on 198 participants who had an indication for colonoscopy at the General Surgery clinic and met the study inclusion criteria. All procedures were conducted by the same endoscopist (Dr. Semra Tutcu Şahin) in the Endoscopy Unit during working hours. Participants were randomly assigned to two groups:
Group 1: Participants whose starting position for colonoscopy was supine (n=97) Group 2: Participants whose starting position for colonoscopy was left lateral (n=101)
During colonoscopy, participants' demographic data, vital signs, and the time required for the endoscopist to reach the cecum were recorded. At the end of the procedure, participants completed a pain scale, and the endoscopist completed an observation scale. The data were entered into the SPSS program and analyzed.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Supine position (SP) | Other | Procedure: Colonoscopy after bowel cleansing, Device: Colonoscopy after bowel cleansingThe first group consisted of patients assigned to the supine position (SP) as the initial position for colonoscopy |
| Lateral Left Horizontal Position (LLP) | Other | Procedure: Colonoscopy after bowel cleansing, Device: Colonoscopy after bowel cleansingThe second group consisted of patients assigned to the left lateral horizontal position (LLP) as the initial position for colonoscopy |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Female and male patients over 18 years of age who have been medically indicated for colonoscopy and have signed the voluntary consent form.
Key exclusion criteria (7 listed)
- Patients under 18 years of age
- Patients who do not give informed consent
- Pregnant women
- Patients requesting sedation
- Patients with an indication for emergency colonoscopy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Colonoscopy after bowel cleansingColonoscopy after bowel cleansing | Procedure or surgery | Lateral Left Horizontal Position (LLP), Supine position (SP) |
| Colonoscopy after bowel cleansingCOLONOSCOPY WITH LEFT LATERAL AND SUPINE POSITION | Device | Lateral Left Horizontal Position (LLP), Supine position (SP) |
Primary outcome
Cecal intubation time
Time frame: During the colonoscopy procedure
Time (in seconds) from insertion of the colonoscope at the anal verge to successful cecal intubation, defined by visualization of the appendiceal orifice and ileocecal valve, recorded by the endoscopist.
3 secondary outcomes
Pain score during colonoscopy
Time frame: Immediately after colonoscopy
Endoscopist-rated procedure difficulty
Time frame: Immediately after colonoscopy
Changes in vital signs during colonoscopy
Time frame: During the colonoscopy procedure
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Apr 2026.
- Background: PubMed 38507105McKechnie T, Heimann L, Kazi T, Jessani G, Lee Y, Sne N, Hong D, Eskicioglu C. Starting position during colonoscopy: a systematic review and meta-analysis of randomized controlled trials. Tech Coloproctol. 2024 Mar 20;28(1):39. doi: 10.1007/s10151-024-02912-8.
- Background: PubMed 34475741Ramai D, Singh J, Brooks OW, Barakat M, Mohan BP, Chandan S, Khan SR, Dhindsa B, Dhaliwal A, Ofosu A, Adler DG. Comparison of left versus right lateral starting position on colonoscopy: a systematic review and meta-analysis of randomized controlled trials. Ann Gastroenterol. 2021 Sep-Oct;34(5):699-704. doi: 10.20524/aog.2021.0639. Epub 2021 Jun 3.
- Background: PubMed 32617389Watanabe J, Park D, Kakehi E, Inoue K, Ishikawa S, Kataoka Y. Efficacy and safety of the starting position during colonoscopy: a systematic review and meta-analysis. Endosc Int Open. 2020 Jul;8(7):E848-E860. doi: 10.1055/a-1149-1541. Epub 2020 Jun 16.
- Background: PubMed 34563640Li N, Lu B, Luo C, Cai J, Lu M, Zhang Y, Chen H, Dai M. Incidence, mortality, survival, risk factor and screening of colorectal cancer: A comparison among China, Europe, and northern America. Cancer Lett. 2021 Dec 1;522:255-268. doi: 10.1016/j.canlet.2021.09.034. Epub 2021 Sep 24.
- Individual participant dataSharing planned: Yes. Anonymized study results
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Colonoscopy after bowel cleansing in people with Colorectal Disorders and Colorectal Neoplasms, run by Manisa Celal Bayar University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cecal intubation time (time frame: During the colonoscopy procedure). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07517848, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Apr 2026.