StrokeNCT07504276
Tele-Rehabilitation vs Conventional Rehabilitation for Cognitive Improvement in Stroke Survivors.
A study testing Tele-rehabilitation and Conventional Rehabilitation in people with Stroke and Cognitive Impairment, run by Riphah International University at 1 site in Pakistan.
Trial summary
This study aims to: Compare tele-rehabilitation and conventional rehabilitation for cognitive improvement after stroke. Evaluate changes in cognitive function using standardized assessment tools. Determine whether tele-rehabilitation is as effective as conventional therapy. Read more about this study
- Who is it for?
- Ages 50 to 80 years
- Conditions the study is for
- Stroke, Cognitive Impairment, Post-Stroke Cognitive Impairment
- What is being tested?
- Tele-rehabilitation and Conventional Rehabilitation
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- 1 sitePakistan
- Study dates
- 31 Mar 2026to 15 Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adults with age 50-80
- Diagnosed with ischemic or hemorrhagic stroke within subacute to chronic phase.
- Moca Score 10-25 score atleast
- For tele-rehab must accessible to a digital device.
Who cannot join
- History of neurodegenerative disorder e.g Alzheimer's Disease and Parkinson's Disease
- Severe Cognitive Impairment
- Lack of access to or inability to use a digital device
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Riphah International University
Islamabad, Punjab Province, 44000
Imran Amjad, Phd, 03324390125, imran.amjad@riphah.edu.pk
About this study
Official title: Comparison Of Tele-Rehabilitation Versus Conventional Rehabilitation To Improve Cognition Among Stroke Survivor.
This study aims to:
- Compare tele-rehabilitation and conventional rehabilitation for cognitive improvement after stroke.
- Evaluate changes in cognitive function using standardized assessment tools.
- Determine whether tele-rehabilitation is as effective as conventional therapy.
- Improve evidence-based rehabilitation strategies for stroke survivors.
Read the detailed description
Stroke is a leading cause of long-term disability and is frequently associated with cognitive impairments affecting attention, memory, executive function, and processing speed, which significantly reduce independence and quality of life among survivors. Cognitive rehabilitation plays a vital role in promoting neuroplasticity and functional recovery after stroke. Conventional rehabilitation, delivered through face-to-face clinical sessions, remains the standard approach; however, tele-rehabilitation has emerged as an accessible and innovative alternative that allows structured cognitive interventions to be delivered remotely using digital platforms. Despite increasing use of tele-rehabilitation, limited comparative evidence exists regarding its effectiveness versus conventional rehabilitation for cognitive improvement in stroke survivors. This randomized controlled trial aims to compare the effectiveness of tele-rehabilitation and conventional rehabilitation over a 8-weeks intervention period. Participants will be randomly allocated into two groups receiving comparable intensity and frequency of cognitive rehabilitation. Cognitive outcomes will be assessed at baseline and post-intervention using standardized tools such as the Montreal Cognitive Assessment (MoCA) and other validated measures such as Stroop Test. The findings of this study will contribute to evidence-based rehabilitation practices and help determine whether tele-rehabilitation can provide an effective alternative to conventional cognitive rehabilitation following stroke.
- Being tested
- Tele-rehabilitation, Conventional Rehabilitation
- Keywords
- Tele-rehabilitation, Conventional Rehabilitation
- Medical subject headings
- Stroke, Cognitive Dysfunction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Tele-rehabilitationBehavioural
Cognitive rehabilitation exercises delivered remotely using video-based sessions, targeting attention, memory, executive function, and processing speed. Sessions will be conducted over 8 weeks.
Conventional RehabilitationBehavioural
In-person cognitive rehabilitation exercises targeting attention, memory, executive function, and processing speed delivered in a clinical setting for 8 weeks.
| Study group | Role | What they receive |
|---|---|---|
| Tele-Rehabilitation Group | Experimental | Participants will receive structured cognitive rehabilitation remotely through telecommunication platforms for 8 weeks. Sessions will be conducted with comparable frequency and intensity to the control group. Receives: Behavioral: Tele-rehabilitation |
| Conventional Rehabilitation Group | Active comparator | Participants will receive face-to-face cognitive rehabilitation sessions in a clinical setting for 8 weeks with similar frequency and duration as the tele-rehabilitation group. Receives: Behavioral: Conventional Rehabilitation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Cognitive Function Measured by Montreal Cognitive Assessment (MoCA)
The Montreal Cognitive Assessment (MoCA) will be used to assess global cognitive function, including attention, memory, executive function, language, and visuospatial abilities. Scores range from 0 to 30, with higher scores indicating better cognitive function.
Measured: Baseline
Change in Cognitive Function Measured by Montreal Cognitive Assessment (MoCA)
The Montreal Cognitive Assessment (MoCA) will be used to assess global cognitive function, including attention, memory, executive function, language, and visuospatial abilities. Scores range from 0 to 30, with higher scores indicating better cognitive function.
Measured: After 8 weeks
Secondary outcomes (2)
Change in Executive Function Measured by stroop Test
The Stroop test will be used to assess selective attention, cognitive flexibility, and inhibitory control. Performance will be evaluated based on completion time and error rate.
Measured: Baseline
Change in Executive Function Measured by stroop Test
The Stroop test will be used to assess selective attention, cognitive flexibility, and inhibitory control. Performance will be evaluated based on completion time and error rate.
Measured: After 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Mar 2026
- Study start31 Mar 2026
- Primary completion30 Jul 2026 (estimated)
- Study completion15 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomly assigned to one of two parallel groups: a tele-rehabilitation group or a conventional rehabilitation group. Both groups will receive structured cognitive rehabilitation interventions with comparable frequency and intensity for 8 weeks.
- Masking
- None (open label)
- Enrolment
- 32 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Imran Amjad, Phd, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07504276
- Sponsor's protocol ID
- REC/02263 Imran Amjad
- Status last verified
- Apr 2026
- First submitted
- 16 Mar 2026
- Last updated
- 3 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison Of Tele-Rehabilitation Versus Conventional Rehabilitation To Improve Cognition Among Stroke Survivor.
- ClinicalTrials.gov ID
- NCT07504276
- Acronym / sponsor ID
- REC/02263 Imran Amjad
- Keywords
- Tele-rehabilitation, Conventional Rehabilitation
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 32 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 31 Mar 2026 (actual)
- Primary completion
- 30 Jul 2026 (estimated)
- Study completion
- 15 Aug 2026 (estimated)
- First posted
- 31 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to:
- Compare tele-rehabilitation and conventional rehabilitation for cognitive improvement after stroke.
- Evaluate changes in cognitive function using standardized assessment tools.
- Determine whether tele-rehabilitation is as effective as conventional therapy.
- Improve evidence-based rehabilitation strategies for stroke survivors.
Detailed description
Stroke is a leading cause of long-term disability and is frequently associated with cognitive impairments affecting attention, memory, executive function, and processing speed, which significantly reduce independence and quality of life among survivors. Cognitive rehabilitation plays a vital role in promoting neuroplasticity and functional recovery after stroke. Conventional rehabilitation, delivered through face-to-face clinical sessions, remains the standard approach; however, tele-rehabilitation has emerged as an accessible and innovative alternative that allows structured cognitive interventions to be delivered remotely using digital platforms. Despite increasing use of tele-rehabilitation, limited comparative evidence exists regarding its effectiveness versus conventional rehabilitation for cognitive improvement in stroke survivors. This randomized controlled trial aims to compare the effectiveness of tele-rehabilitation and conventional rehabilitation over a 8-weeks intervention period. Participants will be randomly allocated into two groups receiving comparable intensity and frequency of cognitive rehabilitation. Cognitive outcomes will be assessed at baseline and post-intervention using standardized tools such as the Montreal Cognitive Assessment (MoCA) and other validated measures such as Stroop Test. The findings of this study will contribute to evidence-based rehabilitation practices and help determine whether tele-rehabilitation can provide an effective alternative to conventional cognitive rehabilitation following stroke.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants will be randomly assigned to one of two parallel groups: a tele-rehabilitation group or a conventional rehabilitation group. Both groups will receive structured cognitive rehabilitation interventions with comparable frequency and intensity for 8 weeks.
| Arm | Type | Receives |
|---|---|---|
| Tele-Rehabilitation Group | Experimental | Behavioral: Tele-rehabilitationParticipants will receive structured cognitive rehabilitation remotely through telecommunication platforms for 8 weeks. Sessions will be conducted with comparable frequency and intensity to the control group. |
| Conventional Rehabilitation Group | Active comparator | Behavioral: Conventional RehabilitationParticipants will receive face-to-face cognitive rehabilitation sessions in a clinical setting for 8 weeks with similar frequency and duration as the tele-rehabilitation group. |
Who may qualify
- Ages
- 50 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Adults with age 50-80
- Diagnosed with ischemic or hemorrhagic stroke within subacute to chronic phase.
- Moca Score 10-25 score atleast
- For tele-rehab must accessible to a digital device.
Key exclusion criteria (3 listed)
- History of neurodegenerative disorder e.g Alzheimer's Disease and Parkinson's Disease
- Severe Cognitive Impairment
- Lack of access to or inability to use a digital device
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Tele-rehabilitationCognitive rehabilitation exercises delivered remotely using video-based sessions, targeting attention, memory, executive function, and processing speed. Sessions will be conducted over 8 weeks. | Behavioural | Tele-Rehabilitation Group |
| Conventional RehabilitationIn-person cognitive rehabilitation exercises targeting attention, memory, executive function, and processing speed delivered in a clinical setting for 8 weeks. | Behavioural | Conventional Rehabilitation Group |
Primary outcome
Change in Cognitive Function Measured by Montreal Cognitive Assessment (MoCA)
Time frame: Baseline
The Montreal Cognitive Assessment (MoCA) will be used to assess global cognitive function, including attention, memory, executive function, language, and visuospatial abilities. Scores range from 0 to 30, with higher scores indicating better cognitive function.
Change in Cognitive Function Measured by Montreal Cognitive Assessment (MoCA)
Time frame: After 8 weeks
The Montreal Cognitive Assessment (MoCA) will be used to assess global cognitive function, including attention, memory, executive function, language, and visuospatial abilities. Scores range from 0 to 30, with higher scores indicating better cognitive function.
2 secondary outcomes
Change in Executive Function Measured by stroop Test
Time frame: Baseline
Change in Executive Function Measured by stroop Test
Time frame: After 8 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Apr 2026.
- Individual participant dataSharing planned: No
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Web-Based Tele-Rehabilitation Using Action Observation and Mirror Therapy for Subacute Stroke: A Randomized Controlled Trial
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Imran Amjad, Phd principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Tele-rehabilitation and Conventional Rehabilitation in people with Stroke and Cognitive Impairment, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 3 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact IMRAN AMJAD, Phd (03324390125, imran.amjad@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Cognitive Function Measured by Montreal Cognitive Assessment (MoCA) (time frame: Baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Apr 2026.