Neck PainNCT07494734
MANUAL THERAPY ON PAIN, DISABILITY AND QUALITY OF LIFE
A study testing Physical therapy and Physical therapy and manual therapy in people with Neck Pain and Neck Pain Musculoskeletal, run by Istanbul Rumeli University at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study is to investigate whether conventional physical therapy combined with manual therapy reduces pain and maintains life support in individuals with chronic mechanical neck pain, compared to conventional physical therapy alone. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Neck Pain, Neck Pain Musculoskeletal
- What is being tested?
- Physical therapy and Physical therapy and manual therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 23 Jul 2026to 25 Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- • Being between 18-65 years of age
- Having neck pain that has lasted for at least three months
- Having a Visual Analog Scale (VAS) score of at least 3
Who cannot join
- Patients not aged 18-60 years
- Pregnant women or those suspected of being pregnant
- Individuals with acute inflammatory diseases
- Individuals with neurological deficits
- Individuals with a positive vertebrobasilar artery test
- Individuals with advanced osteoporosis
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- Individuals who have undergone spinal surgery
- Individuals who have received an injection in the cervical region within the last 3 months
- Individuals with any neurological or psychiatric disorders
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: THE EFFECT OF MANUAL THERAPY ON PAIN, DISABILITY AND QUALITY OF LIFE IN PATIENTS WITH CHRONIC MECHANICAL NECK PAIN
The aim of this study is to investigate whether conventional physical therapy combined with manual therapy reduces pain and maintains life support in individuals with chronic mechanical neck pain, compared to conventional physical therapy alone. The study plans to evaluate the combined benefits of both treatment methods and manual therapy. Pain, quality of life, range of motion, and neck injuries will be assessed in the participants. The treatment protocol will be administered twice a week, for a total of 10 sessions over a 5-week period.
- Conditions
- Neck Pain, Neck Pain Musculoskeletal
- Being tested
- Physical therapy, Physical therapy and manual therapy
- Keywords
- Manual therapy, Quality of life, Disability, Neck pain
- Medical subject headings
- Neck Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Physical therapyOther
Traditional physiotherapy includes transcutaneous electrical nerve stimulation (TENS), infrared device application, and exercise programs.
Physical therapy and manual therapyOther
Cervical region mobilization techniques include bridging, cervical manual traction, rotation with traction, lateral flexion with traction, antero-posterior sliding and lateral sliding techniques with traction. Prior to joint mobilization techniques, bilaterally, soft tissue techniques including myofascial release techniques and ischemic compression will be applied to the cervical paravertebral muscles, upper and middle trapezius, levator scapula, sternocleidomastoid (SCM), anterior-medius posterior scalene muscles, deep and superficial fascia to reduce muscle spasm in the soft tissues and relax the cervical muscles. Transverse friction massage will be applied to the occipital attachment points of the semispinalis capitis and splenius capitis muscles.
| Study group | Role | What they receive |
|---|---|---|
| Physical Therapy | Other | Conventional physical therapy includes transcutaneous electrical nerve stimulation (TENS), infrared device application, and exercise programs. Receives: Other: Physical therapy |
| Physical therapy and Manual therapy | Experimental | Cervical region mobilization techniques include bridging, cervical manual traction, rotation with traction, lateral flexion with traction, antero-posterior sliding and lateral sliding techniques with traction. Prior to joint mobilization techniques, bilaterally, soft tissue techniques including myofascial release techniques and ischemic compression will be applied to the cervical paravertebral muscles, upper and middle trapezius, levator scapula, sternocleidomastoid (SCM), anterior-medius posterior scalene muscles, deep and superficial fascia to reduce muscle spasm in the soft tissues and relax the cervical muscles. Transverse friction massage will be applied to the occipital attachment points of the semispinalis capitis and splenius capitis muscles. Receives: Other: Physical therapy and manual therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain Assessment
Visual Pain Scale
Measured: Baseline and at the end of treatment (week 5)
Range of motion
The data will be recorded in the range of motion assessment section of the patient evaluation form. While the participant is in a seated position, the measurement results of active flexion, extension, right and left rotation, right and left lateral flexion movements of the cervical region will be recorded.
Measured: Baseline and at the end of treatment (week 5)
Disability
Bournemoth Neck :The BDI consists of 10 categories: neck pain intensity, personal care, lifting, reading, headache, concentration, work, driving, sleep, and leisure activities. Individuals included in the study were asked to rate each category between 0 (no disability) and 5 (complete disability) (Vernon, 2008). The total score ranged from 0 (no disability) to 50 (complete disability).
Measured: Baseline and at the end of treatment (week 5)
quality of life
The SF-36 Quality of Life Scale consists of 36 items assessed across 8 separate subscales.
Physical function, social function, general health, fitness, mental health, pain, and physical and emotional role limitations are the subscales of the SF-36.
Each subscale can be scored between 0 and 100.
Measured: Baseline and at the end of treatment (week 5)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Mar 2026
- Study start23 Jul 2026 (estimated)
- Primary completion1 Aug 2026 (estimated)
- Study completion25 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Neck PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Istanbul Rumeli University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ozden Baskan, Istanbul Rumeli University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07494734
- Sponsor's protocol ID
- E-53938333-050-55608
- Status last verified
- Jul 2026
- First submitted
- 20 Mar 2026
- Last updated
- 24 Jul 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- THE EFFECT OF MANUAL THERAPY ON PAIN, DISABILITY AND QUALITY OF LIFE IN PATIENTS WITH CHRONIC MECHANICAL NECK PAIN
- ClinicalTrials.gov ID
- NCT07494734
- Acronym / sponsor ID
- E-53938333-050-55608
- Conditions
- Neck Pain, Neck Pain Musculoskeletal
- Keywords
- Manual therapy, Quality of life, Disability, Neck pain
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Istanbul Rumeli UniversityUniversity, hospital or other
- Study start
- 23 Jul 2026 (estimated)
- Primary completion
- 1 Aug 2026 (estimated)
- Study completion
- 25 Aug 2026 (estimated)
- First posted
- 27 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to investigate whether conventional physical therapy combined with manual therapy reduces pain and maintains life support in individuals with chronic mechanical neck pain, compared to conventional physical therapy alone. The study plans to evaluate the combined benefits of both treatment methods and manual therapy. Pain, quality of life, range of motion, and neck injuries will be assessed in the participants. The treatment protocol will be administered twice a week, for a total of 10 sessions over a 5-week period.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Physical Therapy | Other | Other: Physical therapyConventional physical therapy includes transcutaneous electrical nerve stimulation (TENS), infrared device application, and exercise programs. |
| Physical therapy and Manual therapy | Experimental | Other: Physical therapy and manual therapyCervical region mobilization techniques include bridging, cervical manual traction, rotation with traction, lateral flexion with traction, antero-posterior sliding and lateral sliding techniques with traction. Prior to joint mobilization techniques, bilaterally, soft tissue techniques including myofascial release techniques and ischemic compression will be applied to the cervical paravertebral muscles, upper and middle trapezius, levator scapula, sternocleidomastoid (SCM), anterior-medius posterior scalene muscles, deep and superficial fascia to reduce muscle spasm in the soft tissues and relax the cervical muscles. Transverse friction massage will be applied to the occipital attachment points of the semispinalis capitis and splenius capitis muscles. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- • Being between 18-65 years of age
Key exclusion criteria (9 listed)
- Patients not aged 18-60 years
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Physical therapyTraditional physiotherapy includes transcutaneous electrical nerve stimulation (TENS), infrared device application, and exercise programs. | Other | Physical Therapy |
| Physical therapy and manual therapyCervical region mobilization techniques include bridging, cervical manual traction, rotation with traction, lateral flexion with traction, antero-posterior sliding and lateral sliding techniques with traction. Prior to joint mobilization techniques, bilaterally, soft tissue techniques including myofascial release techniques and ischemic compression will be applied to the cervical paravertebral muscles, upper and middle trapezius, levator scapula, sternocleidomastoid (SCM), anterior-medius posterior scalene muscles, deep and superficial fascia to reduce muscle spasm in the soft tissues and relax the cervical muscles. Transverse friction massage will be applied to the occipital attachment points of the semispinalis capitis and splenius capitis muscles. | Other | Physical therapy and Manual therapy |
Primary outcome
Pain Assessment
Time frame: Baseline and at the end of treatment (week 5)
Visual Pain Scale
Range of motion
Time frame: Baseline and at the end of treatment (week 5)
The data will be recorded in the range of motion assessment section of the patient evaluation form. While the participant is in a seated position, the measurement results of active flexion, extension, right and left rotation, right and left lateral flexion movements of the cervical region will be recorded.
Disability
Time frame: Baseline and at the end of treatment (week 5)
Bournemoth Neck :The BDI consists of 10 categories: neck pain intensity, personal care, lifting, reading, headache, concentration, work, driving, sleep, and leisure activities. Individuals included in the study were asked to rate each category between 0 (no disability) and 5 (complete disability) (Vernon, 2008). The total score ranged from 0 (no disability) to 50 (complete disability).
quality of life
Time frame: Baseline and at the end of treatment (week 5)
The SF-36 Quality of Life Scale consists of 36 items assessed across 8 separate subscales. Physical function, social function, general health, fitness, mental health, pain, and physical and emotional role limitations are the subscales of the SF-36. Each subscale can be scored between 0 and 100.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Jul 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Physical therapy and Physical therapy and manual therapy in people with Neck Pain and Neck Pain Musculoskeletal, run by Istanbul Rumeli University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 24 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain Assessment (time frame: Baseline and at the end of treatment (week 5)). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Jul 2026.