Patients With Multi Drug Resistant Gram-negative BacteriaNCT07487116
Phenotypic and Genotypic Detection of Colistin Resistance
An observational study of Patients With Multi Drug Resistant Gram-negative Bacteria and Colistin Resistance in Bacteria, run by Assiut University.
Trial summary
Evaluation of the disk elution test as reliable routine method for detection of colistin resistant among multidrug resistant gram-negative bacteria compared with broth microdilution. Molecular detection of colistin resistant in multidrug-resistant gram-negative bacteria. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Patients With Multi Drug Resistant Gram-negative Bacteria, Colistin Resistance in Bacteria
- What is being tested?
- disk elution test
- How many people
- 90 participants
- Where
- No sites listed yet
- Study dates
- Aug 2026to Aug 2029
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Multidrug-resistant gram-negative isolates will be collected from clinical specimens (blood, urine, sputum, wound swabs, etc.) obtained from hospitalized patients in Assiut University Hospitals.
Who may be able to join
- -Multidrug-resistant gram-negative isolates will be collected from clinical specimens (blood, urine, sputum, wound swabs, etc.) obtained from hospitalized patients in Assiut University Hospitals.
Who cannot join
- gram-positive bacteria
- carbapenem-sensitive gram-negative bacteria
- repeated sample for same patient or different samples from the same patient
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Phenotypic and Genotypic Detection of Colistin Resistance Among Multi Drug Resistant Gram-negative Bacteria in Assiut University Hospital
- Evaluation of the disk elution test as reliable routine method for detection of colistin resistant among multidrug resistant gram-negative bacteria compared with broth microdilution.
- Molecular detection of colistin resistant in multidrug-resistant gram-negative bacteria.
- Conditions
- Patients With Multi Drug Resistant Gram-negative Bacteria, Colistin Resistance in Bacteria
- Being tested
- disk elution test
- Keywords
- colistin resistant, multi drug resistant gram-negative bacteria, broth microdilution, disk elution test
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
disk elution testDiagnostic test
- Identification of microorganism using conventional methods or Vitek 2 compact system.
- Anti biotic susceptibility test using conventional methods or Vitek 2 compact system.
- For MDR gram negative bacteria: disc elution test and colistin broth microdilution
| Study group | Role | What they receive |
|---|---|---|
| multi drug resistant gram-negative bacteria in Assiut university hospital | Not described Receives: Diagnostic Test: disk elution test |
What is being measured
The primary outcome is the main question the study is designed to answer.
Evaluation of the disk elution test for detection of colistin resistant among multidrug resistant gram-negative bacteria compared with broth microdilution. And Molecular detection of colistin resistant in multidrug-resistant gram-negative bacteria by PCR
Measured: start from 2026 up to 2029
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Mar 2026
- Study startAug 2026 (estimated)
- Primary completionAug 2029 (estimated)
- Study completionAug 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Patients With Multi Drug Resistant Gram-negative BacteriaStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 90 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Christen Saad Welliam, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07487116
- Sponsor's protocol ID
- Assiut organization
- Status last verified
- Mar 2026
- First submitted
- 14 Mar 2026
- Last updated
- 23 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 23 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Phenotypic and Genotypic Detection of Colistin Resistance Among Multi Drug Resistant Gram-negative Bacteria in Assiut University Hospital
- ClinicalTrials.gov ID
- NCT07487116
- Acronym / sponsor ID
- Assiut organization
- Conditions
- Patients With Multi Drug Resistant Gram-negative Bacteria, Colistin Resistance in Bacteria
- Keywords
- colistin resistant, multi drug resistant gram-negative bacteria, broth microdilution, disk elution test
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 90 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- Aug 2026 (estimated)
- Primary completion
- Aug 2029 (estimated)
- Study completion
- Aug 2029 (estimated)
- First posted
- 23 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
- Evaluation of the disk elution test as reliable routine method for detection of colistin resistant among multidrug resistant gram-negative bacteria compared with broth microdilution.
- Molecular detection of colistin resistant in multidrug-resistant gram-negative bacteria.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| multi drug resistant gram-negative bacteria in Assiut university hospital | – | Diagnostic Test: disk elution test |
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Multidrug-resistant gram-negative isolates will be collected from clinical specimens (blood, urine, sputum, wound swabs, etc.) obtained from hospitalized patients in Assiut University Hospitals.
Key inclusion criteria (1 listed)
- -Multidrug-resistant gram-negative isolates will be collected from clinical specimens (blood, urine, sputum, wound swabs, etc.) obtained from hospitalized patients in Assiut University Hospitals.
Key exclusion criteria (3 listed)
- gram-positive bacteria
- carbapenem-sensitive gram-negative bacteria
- repeated sample for same patient or different samples from the same patient
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| disk elution test* Identification of microorganism using conventional methods or Vitek 2 compact system. * Anti biotic susceptibility test using conventional methods or Vitek 2 compact system. * For MDR gram negative bacteria: disc elution test and colistin broth microdilution | Diagnostic test | multi drug resistant gram-negative bacteria in Assiut university hospital |
Primary outcome
Evaluation of the disk elution test for detection of colistin resistant among multidrug resistant gram-negative bacteria compared with broth microdilution. And Molecular detection of colistin resistant in multidrug-resistant gram-negative bacteria by PCR
Time frame: start from 2026 up to 2029
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Mar 2026.
- Individual participant dataSharing planned: Undecided
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
An observational study of Patients With Multi Drug Resistant Gram-negative Bacteria and Colistin Resistance in Bacteria, run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 23 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact christen william, Master's degree in clinic path (+201283938578, christeensaad50@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Evaluation of the disk elution test for detection of colistin resistant among multidrug resistant gram-negative bacteria compared with broth microdilution. And Molecular detection of colistin resistant in multidrug-resistant gram-negative bacteria by PCR (time frame: start from 2026 up to 2029). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Mar 2026.