Polytrauma PatientsPolytrauma ICUNCT07482267
Evaluation of Patients Suffering From Polytrauma Admitted to the ICU
An observational study of Polytrauma Patients, run by Jessa Hospital at 1 site in Belgium.
Trial summary
The primary objective of this study is to assess the number of polytrauma patients admitted to the Intensive Care Unit. In addition, we aim to describe their clinical characteristics, therapeutic management, and clinical outcomes. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Polytrauma Patients
- How many people
- 417 participants
- Where
- 1 siteBelgium
- Study dates
- 10 Apr 2025to 31 Dec 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: All patients with a polytrauma admitted to the ICU between 01/01/2020 and 31/12/2025
Who may be able to join
- All patients with a polytrauma admitted to the ICU between 01/01/2020 and 31/12/2025
Who cannot join
- Younger than 18 years of age
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Evaluation of Patients Suffering From Polytrauma Admitted to the ICU: a Retrospective Cohort Study.
The primary objective of this study is to assess the number of polytrauma patients admitted to the Intensive Care Unit. In addition, we aim to describe their clinical characteristics, therapeutic management, and clinical outcomes.
Read the detailed description
Trauma constitutes a major contributor to global mortality and long-term physical disability. The principal causes of traumatic injury include road traffic accidents, falls, drowning, burns, poisoning, interpersonal violence, and acts of war. Collectively, these causes account for approximately 9% of global deaths.
Within the broader population of trauma patients, polytrauma patients represent a distinct and clinically significant subgroup, accounting for approximately 25% of trauma-related hospital admissions. Polytrauma is not merely defined as the coexistence of multiple injuries, but rather as a complex clinical condition characterized by a high risk of complications and progressive physiological deterioration. In the early post-traumatic phase, patients may develop severe hemorrhage, hemorrhagic shock, respiratory compromise, or traumatic brain injury. In the subsequent phase, systemic inflammatory response syndrome, sepsis, and multiple organ dysfunction syndrome may occur.
Advances in injury prevention strategies and improvements in trauma care have led to increased survival during the early stages following injury. As a result, a growing number of polytrauma patients require admission to the Intensive Care Unit (ICU), underscoring the need to optimize critical care delivery in this population. The provision of high-quality, evidence-based care depends on the systematic collection and analysis of comprehensive clinical data to facilitate continuous improvement in treatment strategies and outcomes.
- Conditions
- Polytrauma Patients
- Keywords
- Polytrauma, Intensive Care Unit
- Medical subject headings
- Multiple Trauma
What is being measured
The primary outcome is the main question the study is designed to answer.
Mortality
All patients with a polytrauma admitted to the ICU between 01/01/2020 and 31/12/2025
Measured: through study completion, an average of 1 year.
Secondary outcomes (1)
Length of stay
The length of stay at ICU and hospital of all patients with a polytrauma admitted to the ICU between 01/01/2020 and 31/12/2025
Measured: through study completion, an average of 1 year.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Mar 2026
- Study start10 Apr 2025
- Primary completion31 Dec 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Polytrauma PatientsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 417 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Jessa Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Stessel Björn, Jessa Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07482267
- Sponsor's protocol ID
- 2025/039
- Acronym
- Polytrauma ICU
- Status last verified
- Mar 2026
- First submitted
- 23 Feb 2026
- Last updated
- 19 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of Patients Suffering From Polytrauma Admitted to the ICU: a Retrospective Cohort Study.
- ClinicalTrials.gov ID
- NCT07482267
- Acronym / sponsor ID
- Polytrauma ICU / 2025/039
- Conditions
- Polytrauma Patients
- Keywords
- Polytrauma, Intensive Care Unit
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 417 participants (estimated)
- Lead sponsor
- Jessa HospitalUniversity, hospital or other
- Study start
- 10 Apr 2025 (actual)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 19 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The primary objective of this study is to assess the number of polytrauma patients admitted to the Intensive Care Unit. In addition, we aim to describe their clinical characteristics, therapeutic management, and clinical outcomes.
Detailed description
Trauma constitutes a major contributor to global mortality and long-term physical disability. The principal causes of traumatic injury include road traffic accidents, falls, drowning, burns, poisoning, interpersonal violence, and acts of war. Collectively, these causes account for approximately 9% of global deaths.
Within the broader population of trauma patients, polytrauma patients represent a distinct and clinically significant subgroup, accounting for approximately 25% of trauma-related hospital admissions. Polytrauma is not merely defined as the coexistence of multiple injuries, but rather as a complex clinical condition characterized by a high risk of complications and progressive physiological deterioration. In the early post-traumatic phase, patients may develop severe hemorrhage, hemorrhagic shock, respiratory compromise, or traumatic brain injury. In the subsequent phase, systemic inflammatory response syndrome, sepsis, and multiple organ dysfunction syndrome may occur.
Advances in injury prevention strategies and improvements in trauma care have led to increased survival during the early stages following injury. As a result, a growing number of polytrauma patients require admission to the Intensive Care Unit (ICU), underscoring the need to optimize critical care delivery in this population. The provision of high-quality, evidence-based care depends on the systematic collection and analysis of comprehensive clinical data to facilitate continuous improvement in treatment strategies and outcomes.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- All patients with a polytrauma admitted to the ICU between 01/01/2020 and 31/12/2025
Key inclusion criteria (1 listed)
- All patients with a polytrauma admitted to the ICU between 01/01/2020 and 31/12/2025
Key exclusion criteria (1 listed)
- Younger than 18 years of age
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Mortality
Time frame: through study completion, an average of 1 year.
All patients with a polytrauma admitted to the ICU between 01/01/2020 and 31/12/2025
1 secondary outcome
Length of stay
Time frame: through study completion, an average of 1 year.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Mar 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Polytrauma Patients, run by Jessa Hospital at 1 site in Belgium.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 19 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Belgium. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mortality (time frame: through study completion, an average of 1 year.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Mar 2026.