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DysphagiaNCT07479680

Effect of Direct Chin-tuck Against Resistance on Swallowing Function

A study testing dCTAR in people with Dysphagia, run by National Taiwan University Hospital at 1 site in Taiwan.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

Chin-tuck Against Resistance (CTAR) is a widely used training method in swallowing rehabilitation that strengthens the suprahyoid muscles, enhancing their contraction during swallowing and promoting the anterior-superior movement of the hyoid-larynx complex, thus improving the swallowing process. In 2022, Dr. Read more about this study

Who is it for?
Ages 18 to 90 yearsHealthy volunteers can take part
Conditions the study is for
Dysphagia
What is being tested?
dCTAR
Could I receive a placebo?
No, everyone receives an active treatment
How many people
60 participants
Where
1 siteTaiwan
Study dates
14 Aug 2024to 10 Jul 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 90 years
  • All sexes
  • Healthy volunteers accepted
  • Adult, Older adult

Who may be able to join

  • Age 18-90 years old
  • Be conscious and able to cooperate with the inspection
  • Patients with dysphagia after stroke (Functional oral intake scale, FOIS 1-6) or healthy subjects (FOIS 7)

Who cannot join

  • Have a history of head and neck cancer
  • Other medical history known to cause dysphagia (such as neck surgery, intubation, etc.)
  • Ultrasound examination cannot be performed if there are wounds, air incisions or other structural abnormalities in the neck

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Ming-Yen Hsiao, Ph.D contact

886-2-23123456 ext. 67316

myferrant@gmail.com

Taiwan1 site, 1 recruiting

  • National taiwan university hospital

    Taipei, Taipei, 100

    Ming-Yen Hsiao, 886-2-23123456 ex 61316, myferrant@gmail.com

    Recruiting

Other trials in Taiwan

About this study

Chin-tuck Against Resistance (CTAR) is a widely used training method in swallowing rehabilitation that strengthens the suprahyoid muscles, enhancing their contraction during swallowing and promoting the anterior-superior movement of the hyoid-larynx complex, thus improving the swallowing process. In 2022, Dr. Meng et al. discovered that for a patient with ineffective relaxation of the cricopharyngeal muscle, swallowing while performing CTAR significantly increased the immediate relaxation of the cricopharyngeal muscle, allowing the contrast agent to enter the esophagus smoothly. This method is named direct Chin-tuck Against Resistance (dCTAR). This study aims to evaluate the effectiveness of dCTAR in improving swallowing function, its impact on suprahyoid muscle contraction and hyoid-larynx complex movement, and further explore the relationship between tongue strength and bite force with the effectiveness of dCTAR. The study will recruit healthy subjects and dysphagia patients to investigate the relationship between tongue strength, bite force, and the effectiveness of dCTAR. This study uses ultrasound to measure changes in the cross-sectional area of the suprahyoid muscles and the elevation of the hyoid-larynx complex during swallowing before and after dCTAR; and the changes in these parameters after a total of 10 repeated CTAR training sessions over two weeks.

Conditions
Dysphagia
Being tested
dCTAR
Keywords
direct Chin-tuck Against Resistance(dCTAR), hyoid-larynx complex, dysphagia
Medical subject headings
Deglutition Disorders

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • dCTAROther

    Perform repeated CTAR exercise training for 15 minutes a day for a total of about 10 times in two weeks. After training, the swallowing function (FOIS), the movement amount and speed of the hyoid-larynx complex during swallowing, the thickness and cross-sectional area of the suprahyoid muscles, and changes in tongue muscle strength were tracked.

Study groups in NCT07479680
Study groupRoleWhat they receive
Post-stroke dysphagia patientsExperimentalNot described
Receives: Other: dCTAR
healthy subjectsNo interventionNot described

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. hyoid-larynx movement

    Use ultrasound to measure the movement of the hyoid-larynx complex during swallowing during normal swallowing and dCTAR movements.

    Measured: 2-3 weeks

Secondary outcomes (2)

  1. Function Oral lntake Scale

    score 1-7, higher indicate better outcomes

    Measured: 2-3 weeks

  2. Tongue pressure

    Tongue pressure measured by IOPI

    Measured: 2-3 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted18 Mar 2026
  2. Study start14 Aug 2024
  3. Primary completion10 Jul 2026 (estimated)
  4. Study completion10 Jul 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Non-randomised
Intervention model
Parallel groups
Masking
None (open label)
Enrolment
60 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07479680
Sponsor's protocol ID
202405166RINC
Status last verified
Nov 2025
First submitted
13 Jun 2024
Last updated
18 Mar 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No

Publications

  • Park JS, An DH, Oh DH, Chang MY. Effect of chin tuck against resistance exercise on patients with dysphagia following stroke: A randomized pilot study. NeuroRehabilitation. 2018;42(2):191-197. doi: 10.3233/NRE-172250.

    PubMed 29562558

  • Park JS, Hwang NK. Chin tuck against resistance exercise for dysphagia rehabilitation: A systematic review. J Oral Rehabil. 2021 Aug;48(8):968-977. doi: 10.1111/joor.13181. Epub 2021 Jun 12.

    PubMed 33973284

  • Sze WP, Yoon WL, Escoffier N, Rickard Liow SJ. Evaluating the Training Effects of Two Swallowing Rehabilitation Therapies Using Surface Electromyography--Chin Tuck Against Resistance (CTAR) Exercise and the Shaker Exercise. Dysphagia. 2016 Apr;31(2):195-205. doi: 10.1007/s00455-015-9678-2. Epub 2016 Feb 2.

    PubMed 26837612

  • Yoon WL, Khoo JK, Rickard Liow SJ. Chin tuck against resistance (CTAR): new method for enhancing suprahyoid muscle activity using a Shaker-type exercise. Dysphagia. 2014 Apr;29(2):243-8. doi: 10.1007/s00455-013-9502-9. Epub 2013 Dec 15.

    PubMed 24337867

  • Meng NH, Tsou YA, Yang PY, Chen HC, Chang CW. Dysphagia in a Patient with Esophageal and Hypopharyngeal Cancers After Esophageal Reconstruction: A Pharyngeal Clearance Facilitating Maneuver. Dysphagia. 2022 Oct;37(5):1337-1339. doi: 10.1007/s00455-021-10394-1. Epub 2022 Jan 9. No abstract available.

    PubMed 34999931

  • Chen YC, Hsiao MY, Wang YC, Fu CP, Wang TG. Reliability of Ultrasonography in Evaluating Hyoid Bone Movement. J Med Ultrasound. 2017 Apr-Jun;25(2):90-95. doi: 10.1016/j.jmu.2017.01.002. Epub 2017 Feb 16.

    PubMed 30065466

  • Hsiao MY, Chang YC, Chen WS, Chang HY, Wang TG. Application of ultrasonography in assessing oropharyngeal dysphagia in stroke patients. Ultrasound Med Biol. 2012 Sep;38(9):1522-8. doi: 10.1016/j.ultrasmedbio.2012.04.017. Epub 2012 Jun 12.

    PubMed 22698507

  • Kwan BC, Butler JE, Hudson AL, McKenzie DK, Bilston LE, Gandevia SC. A novel ultrasound technique to measure genioglossus movement in vivo. J Appl Physiol (1985). 2014 Sep 1;117(5):556-62. doi: 10.1152/japplphysiol.01257.2013. Epub 2014 Jun 26.

    PubMed 24970850

  • Macrae PR, Jones RD, Myall DJ, Melzer TR, Huckabee ML. Cross-sectional area of the anterior belly of the digastric muscle: comparison of MRI and ultrasound measures. Dysphagia. 2013 Sep;28(3):375-80. doi: 10.1007/s00455-012-9443-8. Epub 2013 Jan 20.

    PubMed 23334304

  • Van Den Engel-Hoek L, Lagarde M, Van Alfen N. Ultrasound of oral and masticatory muscles: Why every neuromuscular swallow team should have an ultrasound machine. Clin Anat. 2017 Mar;30(2):183-193. doi: 10.1002/ca.22818. Epub 2017 Jan 24.

    PubMed 27935170

  • Van Den Engel-Hoek L, Van Alfen N, De Swart BJ, De Groot IJ, Pillen S. Quantitative ultrasound of the tongue and submental muscles in children and young adults. Muscle Nerve. 2012 Jul;46(1):31-7. doi: 10.1002/mus.23277. Epub 2012 May 29.

    PubMed 22644805

  • Yabunaka K, Konishi H, Nakagami G, Sanada H, Iizaka S, Sanada S, Ohue M. Ultrasonographic evaluation of geniohyoid muscle movement during swallowing: a study on healthy adults of various ages. Radiol Phys Technol. 2012 Jan;5(1):34-9. doi: 10.1007/s12194-011-0132-3. Epub 2011 Aug 23.

    PubMed 21861155

  • Hsiao, M.-Y., L.K. Wahyuni, and T.-G. Wang, Ultrasonography in Assessing Oropharyngeal Dysphagia. Journal of Medical Ultrasound, 2013. 21(4): p. 181-188.

Questions about this trial

What is this clinical trial studying?

A study testing dCTAR in people with Dysphagia, run by National Taiwan University Hospital at 1 site in Taiwan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 18 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Ming-Yen Hsiao, Ph.D (886-2-23123456 ext. 67316, myferrant@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

hyoid-larynx movement (time frame: 2-3 weeks). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07479680, which also lists 13 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Mar 2026.

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