Lower-Limb StrengthNCT07461701
Study of 15% Versus 30% Velocity Loss Thresholds During Bodyweight Squats and Their Effects on Strength and Endurance in Young Women
A study testing Body-weight squat training (15% velocity loss threshold) and Body-weight squat training (30% velocity loss threshold) in people with Lower-Limb Strength and Muscular Endurance, run by University of Health Sciences Lahore at 1 site in Pakistan.
Trial summary
The goal of this clinical trial is to learn how two different velocity loss thresholds (15% and 30%) during bodyweight squats affect strength and endurance in non-athletic young women aged 18-25 years. Read more about this study
- Who is it for?
- Ages 18 to 25 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Lower-Limb Strength, Muscular Endurance, Velocity-Based Resistance Training
- What is being tested?
- Body-weight squat training (15% velocity loss threshold) and Body-weight squat training (30% velocity loss threshold)
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 52 participants
- Where
- 1 sitePakistan
- Study dates
- 22 Feb 2026to 19 Apr 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Female participants
- 18-25 Years
- Body Mass Index less than 30 kg/m²
- Low physical activity level
- Able to perform body weight squats without pain or assistance
Who cannot join
- Recent Cardiovascular Disease
- Current Patellar Injury
- Recent Musculoskeletal Injuries
- Current Pregnancy or Postpartum Period within the last 6 months
- Participation in resistance or endurance training programs in the past 6 months.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
University of Health Sciences
Lahore, Punjab Province, 39350
Dr. Wajeeha Mahmood PT, PhD(scholar),MSNMPT,PPDPT,BSPT, +92 334 9867317, higheraimz@hotmail.com
Shiza Maryam, DPT
About this study
Official title: Effect of 15% Versus 30% Intra-Set Velocity Loss Thresholds During Bodyweight Squats on Lower-Limb Strength and Muscular Endurance in Non-Athletic Young Female Adults.
The goal of this clinical trial is to learn how two different velocity loss thresholds (15% and 30%) during bodyweight squats affect strength and endurance in non-athletic young women aged 18-25 years.
The main questions it aims to answer are:
Read more
Does a lower velocity loss threshold (15%) during bodyweight squats improve lower-limb strength? Does a higher velocity loss threshold (30%) during bodyweight squats improve muscular endurance? Researchers will compare the two groups (15% vs. 30% velocity loss) to see if one approach works better for strength and endurance.
Participants will:
Perform bodyweight squats three times per week for six weeks. Be randomly assigned to either the 15% or 30% velocity loss group. Complete strength and endurance tests before and after the program
Read the detailed description
This randomized controlled trial will examine the effects of two intra-set velocity loss (VL) thresholds, 15% and 30%, during bodyweight squats on lower-limb strength and muscular endurance in non-athletic young female adults. Velocity-based resistance training (VBRT) is increasingly used to regulate training intensity and volume, but most existing evidence comes from trained male athletes performing loaded exercises. There is limited research on accessible, equipment-free protocols such as bodyweight squats, particularly in underrepresented populations such as non-athletic young women.
A total of 52 female university students aged 18-25 years will be recruited using the International Physical Activity Questionnaire-Short Form (IPAQ-SF). Participants will be randomly assigned to either the 15% Velocity Loss group or the 30% Velocity Loss group, with 26 participants per group. Both groups will perform bodyweight squat sessions three times per week for six weeks.
Outcomes will be assessed before and after the intervention by a blinded assessor. Primary outcomes include lower-limb strength and muscular endurance. Data will be analyzed using Statistical Package for the Social Sciences (SPSS) version 27, with statistical significance set at p < 0.05.
The study aims to determine whether a lower Velocity Loss threshold (15%) produces comparable improvements in strength and endurance to a higher Velocity Loss threshold (30%) when using bodyweight squats. Findings will provide evidence to guide physiotherapists, exercise professionals, and health educators in designing safe, accessible, and effective training programs for non-athletic young women.
- Being tested
- Body-weight squat training (15% velocity loss threshold), Body-weight squat training (30% velocity loss threshold)
- Keywords
- Velocity Loss Thresholds, Bodyweight Squats, Lower-Limb Strength, Muscular Endurance, Non-Athletic Young Women, Resistance Training, Physiotherapy Exercise Prescription, Randomized Controlled Trial
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Body-weight squat training (15% velocity loss threshold)Behavioural
Participants will perform supervised body-weight squat training using an intra-set velocity loss threshold of 15%. Velocity loss will be monitored using standardized metronome cadence as a proxy for movement velocity. Training frequency, volume, and progression will be consistent across groups except for the velocity loss threshold.
Body-weight squat training (30% velocity loss threshold)Behavioural
Participants will perform supervised body-weight squat training using an intra-set velocity loss threshold of 30%. Velocity loss will be monitored using standardized metronome cadence as a proxy for movement velocity. Training frequency, volume, and progression will be consistent across groups except for the velocity loss threshold.
| Study group | Role | What they receive |
|---|---|---|
| 15% Velocity Loss Group | Experimental | Participants will perform body-weight squats with intra-set velocity loss threshold of 15%, monitored using metronome cadence as a proxy for movement velocity. Receives: Behavioral: Body-weight squat training (15% velocity loss threshold) |
| 30% Velocity Loss Group | Active comparator | Participants will perform body-weight squats with intra-set velocity loss threshold of 30%, monitored using metronome cadence as a proxy for movement velocity. Receives: Behavioral: Body-weight squat training (30% velocity loss threshold) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Lower-limb muscular strength
Total number of completed chair stands performed in 30 seconds, measured in repetitions.
Measured: Baseline and Week 6
Lower-limb muscular endurance
Total time maintaining the wall-sit position, measured in seconds.
Measured: Baseline and Week 6
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Mar 2026
- Study start22 Feb 2026
- Primary completion5 Apr 2026 (estimated)
- Study completion19 Apr 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Lower-Limb StrengthStudies of the same condition, open and under way.
- More trials run by University of Health Sciences LahoreThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 52 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Health Sciences Lahore
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Shiza Maryam, University of Health Sciences Lahore
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07461701
- Sponsor's protocol ID
- UHS/USERC-26/SEC/89
- Status last verified
- Mar 2026
- First submitted
- 24 Feb 2026
- Last updated
- 10 Mar 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 10 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of 15% Versus 30% Intra-Set Velocity Loss Thresholds During Bodyweight Squats on Lower-Limb Strength and Muscular Endurance in Non-Athletic Young Female Adults.
- ClinicalTrials.gov ID
- NCT07461701
- Acronym / sponsor ID
- UHS/USERC-26/SEC/89
- Keywords
- Velocity Loss Thresholds, Bodyweight Squats, Lower-Limb Strength, Muscular Endurance, Non-Athletic Young Women, Resistance Training, Physiotherapy Exercise Prescription, Randomized Controlled Trial
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 52 participants (estimated)
- Lead sponsor
- University of Health Sciences LahoreUniversity, hospital or other
- Study start
- 22 Feb 2026 (actual)
- Primary completion
- 5 Apr 2026 (estimated)
- Study completion
- 19 Apr 2026 (estimated)
- First posted
- 10 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to learn how two different velocity loss thresholds (15% and 30%) during bodyweight squats affect strength and endurance in non-athletic young women aged 18-25 years.
The main questions it aims to answer are:
Does a lower velocity loss threshold (15%) during bodyweight squats improve lower-limb strength? Does a higher velocity loss threshold (30%) during bodyweight squats improve muscular endurance? Researchers will compare the two groups (15% vs. 30% velocity loss) to see if one approach works better for strength and endurance.
Participants will:
Perform bodyweight squats three times per week for six weeks. Be randomly assigned to either the 15% or 30% velocity loss group. Complete strength and endurance tests before and after the program
Detailed description
This randomized controlled trial will examine the effects of two intra-set velocity loss (VL) thresholds, 15% and 30%, during bodyweight squats on lower-limb strength and muscular endurance in non-athletic young female adults. Velocity-based resistance training (VBRT) is increasingly used to regulate training intensity and volume, but most existing evidence comes from trained male athletes performing loaded exercises. There is limited research on accessible, equipment-free protocols such as bodyweight squats, particularly in underrepresented populations such as non-athletic young women.
A total of 52 female university students aged 18-25 years will be recruited using the International Physical Activity Questionnaire-Short Form (IPAQ-SF). Participants will be randomly assigned to either the 15% Velocity Loss group or the 30% Velocity Loss group, with 26 participants per group. Both groups will perform bodyweight squat sessions three times per week for six weeks.
Outcomes will be assessed before and after the intervention by a blinded assessor. Primary outcomes include lower-limb strength and muscular endurance. Data will be analyzed using Statistical Package for the Social Sciences (SPSS) version 27, with statistical significance set at p < 0.05.
The study aims to determine whether a lower Velocity Loss threshold (15%) produces comparable improvements in strength and endurance to a higher Velocity Loss threshold (30%) when using bodyweight squats. Findings will provide evidence to guide physiotherapists, exercise professionals, and health educators in designing safe, accessible, and effective training programs for non-athletic young women.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| 15% Velocity Loss Group | Experimental | Behavioral: Body-weight squat training (15% velocity loss threshold)Participants will perform body-weight squats with intra-set velocity loss threshold of 15%, monitored using metronome cadence as a proxy for movement velocity. |
| 30% Velocity Loss Group | Active comparator | Behavioral: Body-weight squat training (30% velocity loss threshold)Participants will perform body-weight squats with intra-set velocity loss threshold of 30%, monitored using metronome cadence as a proxy for movement velocity. |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Female participants
- 18-25 Years
- Body Mass Index less than 30 kg/m²
- Low physical activity level
- Able to perform body weight squats without pain or assistance
Key exclusion criteria (5 listed)
- Recent Cardiovascular Disease
- Current Patellar Injury
- Recent Musculoskeletal Injuries
- Current Pregnancy or Postpartum Period within the last 6 months
- Participation in resistance or endurance training programs in the past 6 months.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Body-weight squat training (15% velocity loss threshold)Participants will perform supervised body-weight squat training using an intra-set velocity loss threshold of 15%. Velocity loss will be monitored using standardized metronome cadence as a proxy for movement velocity. Training frequency, volume, and progression will be consistent across groups except for the velocity loss threshold. | Behavioural | 15% Velocity Loss Group |
| Body-weight squat training (30% velocity loss threshold)Participants will perform supervised body-weight squat training using an intra-set velocity loss threshold of 30%. Velocity loss will be monitored using standardized metronome cadence as a proxy for movement velocity. Training frequency, volume, and progression will be consistent across groups except for the velocity loss threshold. | Behavioural | 30% Velocity Loss Group |
Primary outcome
Lower-limb muscular strength
Time frame: Baseline and Week 6
Total number of completed chair stands performed in 30 seconds, measured in repetitions.
Lower-limb muscular endurance
Time frame: Baseline and Week 6
Total time maintaining the wall-sit position, measured in seconds.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 10 Mar 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Body-weight squat training (15% velocity loss threshold) and Body-weight squat training (30% velocity loss threshold) in people with Lower-Limb Strength and Muscular Endurance, run by University of Health Sciences Lahore at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 10 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Shiza Maryam, Doctor of Physical Therapy (+92 333 8813397, shiza.maryam.pk@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Lower-limb muscular strength (time frame: Baseline and Week 6). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Mar 2026.