Post-Stroke Cognitive Impairment (PSCI)AICoRe-StrokeNCT07452276
Artificial Intelligence-Based Cognitive Training in Patients With Stroke
A study testing cognifit Mobile Application for Cognitive Training and Conventional Cognitive Rehabilitation in people with Post-Stroke Cognitive Impairment (PSCI) and Stroke, run by Omima Alaa Eldin Hussein at 1 site in Egypt.
Trial summary
This study would answer the following question:Does AI application-based training improve cognitive function in Patients with Stroke? The aims of this study: To investigate the efficacy of AI application-based training on cognitive function in stroke patients. Read more about this study
- Who is it for?
- Ages 45 to 60 years
- Conditions the study is for
- Post-Stroke Cognitive Impairment (PSCI), Stroke, Artifical Intelligence
- What is being tested?
- cognifit Mobile Application for Cognitive Training and Conventional Cognitive Rehabilitation
- Type of treatment
- Medical device, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jan 2026to 6 Jun 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patient's age will range from 45- 60 years.
- Diagnosis of stroke in the chronic stage (≥3 months post-onset).
- Presence of cognitive impairment confirmed by a Montreal Cognitive Assessment (MoCA) score ≤ 26.
- Medically stable and able to follow instructions.
- patients with memory deficits following stroke
Who cannot join
- Patients will be excluded if they have:
- Severe visual, hearing, or speech impairments prevent participation.
- History of other neurological or psychiatric disorders.
- Unstable cardiovascular or systemic disease.
- Severe depression (Beck Depression Inventory > 29).
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Physical therapy- Cairo University
Cairo, Egypt, 62517
Omima Alaa Eldin Hussein, +201207838324, omimaalaa27@gmail.com
About this study
Official title: Effect of Artificial Intelligence-Based Training on Cognitive Functions in Patients With Stroke
This study would answer the following question:Does AI application-based training improve cognitive function in Patients with Stroke?
The aims of this study:
To investigate the efficacy of AI application-based training on cognitive function in stroke patients.
- Being tested
- cognifit Mobile Application for Cognitive Training, Conventional Cognitive Rehabilitation
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
cognifit Mobile Application for Cognitive TrainingDevice
A structured artificial intelligence-based cognitive training program targeting attention, memory, executive function, and processing speed in patients with stroke. The program provides adaptive, individualized exercises based on participant performance.
Conventional Cognitive RehabilitationBehavioural
A structured conventional rehabilitation program consisting of aerobic exercises, relaxation exercises, and traditional paper-based cognitive exercises for patients with stroke. The duration and frequency of treatment are matched to the experimental group.
| Study group | Role | What they receive |
|---|---|---|
| AI-Based Cognitive Training | Experimental | Participants receive artificial intelligence-based cognitive training in stroke patients. The AI program is designed to target multiple cognitive domains including attention, memory, executive function, and processing speed. Receives: Device: cognifit Mobile Application for Cognitive Training |
| Conventional Physical Therapy | Active comparator | Participants receive a conventional rehabilitation program consisting of aerobic exercises, relaxation exercises, and traditional paper-based cognitive exercises, in addition to standard physical therapy. Receives: Behavioral: Conventional Cognitive Rehabilitation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Cognitive Function
Change in Global Cognitive Function Measured by the Montreal Cognitive Assessment (MoCA) Global cognitive function will be assessed using the Montreal Cognitive Assessment (MoCA), a one-page, 30-point cognitive screening tool that evaluates attention, memory, executive function, language, visuospatial abilities, abstraction, calculation, and orientation. The test takes approximately 10 minutes to administer.
Scores range from 0 to 30, with higher scores indicating better cognitive function. A score of less than 26 indicates cognitive impairment.
Measured: Baseline and 6 weeks post-intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Mar 2026
- Study start1 Jan 2026
- Primary completion1 Feb 2026
- Study completion6 Jun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Post-Stroke Cognitive Impairment (PSCI)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Care provider
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Omima Alaa Eldin Hussein
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Omima Alaa Eldin Hussein, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07452276
- Sponsor's protocol ID
- P.T.REC/012/006268
- Acronym
- AICoRe-Stroke
- Status last verified
- Jan 2026
- First submitted
- 19 Feb 2026
- Last updated
- 5 Mar 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 5 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Artificial Intelligence-Based Training on Cognitive Functions in Patients With Stroke
- ClinicalTrials.gov ID
- NCT07452276
- Acronym / sponsor ID
- AICoRe-Stroke / P.T.REC/012/006268
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Omima Alaa Eldin HusseinUniversity, hospital or other
- Study start
- 1 Jan 2026 (actual)
- Primary completion
- 1 Feb 2026 (actual)
- Study completion
- 6 Jun 2026 (estimated)
- First posted
- 5 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study would answer the following question:Does AI application-based training improve cognitive function in Patients with Stroke?
The aims of this study:
To investigate the efficacy of AI application-based training on cognitive function in stroke patients.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, care provider)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| AI-Based Cognitive Training | Experimental | Device: cognifit Mobile Application for Cognitive TrainingParticipants receive artificial intelligence-based cognitive training in stroke patients. The AI program is designed to target multiple cognitive domains including attention, memory, executive function, and processing speed. |
| Conventional Physical Therapy | Active comparator | Behavioral: Conventional Cognitive RehabilitationParticipants receive a conventional rehabilitation program consisting of aerobic exercises, relaxation exercises, and traditional paper-based cognitive exercises, in addition to standard physical therapy. |
Who may qualify
- Ages
- 45 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Patient's age will range from 45- 60 years.
Key exclusion criteria (5 listed)
- Patients will be excluded if they have:
- Severe visual, hearing, or speech impairments prevent participation.
- History of other neurological or psychiatric disorders.
- Unstable cardiovascular or systemic disease.
- Severe depression (Beck Depression Inventory > 29).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| cognifit Mobile Application for Cognitive TrainingA structured artificial intelligence-based cognitive training program targeting attention, memory, executive function, and processing speed in patients with stroke. The program provides adaptive, individualized exercises based on participant performance. | Device | AI-Based Cognitive Training |
| Conventional Cognitive RehabilitationA structured conventional rehabilitation program consisting of aerobic exercises, relaxation exercises, and traditional paper-based cognitive exercises for patients with stroke. The duration and frequency of treatment are matched to the experimental group. | Behavioural | Conventional Physical Therapy |
Primary outcome
Change in Cognitive Function
Time frame: Baseline and 6 weeks post-intervention
Change in Global Cognitive Function Measured by the Montreal Cognitive Assessment (MoCA) Global cognitive function will be assessed using the Montreal Cognitive Assessment (MoCA), a one-page, 30-point cognitive screening tool that evaluates attention, memory, executive function, language, visuospatial abilities, abstraction, calculation, and orientation. The test takes approximately 10 minutes to administer. Scores range from 0 to 30, with higher scores indicating better cognitive function. A score of less than 26 indicates cognitive impairment.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Mar 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing cognifit Mobile Application for Cognitive Training and Conventional Cognitive Rehabilitation in people with Post-Stroke Cognitive Impairment (PSCI) and Stroke, run by Omima Alaa Eldin Hussein at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 5 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Omima Alaa Eldin Hussein (+201207838324, omimaalaa27@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Cognitive Function (time frame: Baseline and 6 weeks post-intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Mar 2026.