Erectile DysfunctionNCT07442396
The Effectiveness of Exercise in the Treatment of Erectile Dysfunction and Premature Ejaculation
A study testing exercise in people with Erectile Dysfunction and Premature Ejaculation, run by Uskudar University at 1 site in Turkey (Türkiye).
Trial summary
The aim is to investigate the effectiveness of exercise in the treatment of erectile dysfunction and premature ejaculation. Read more about this study
- Who is it for?
- Ages 25 to 45 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Erectile Dysfunction, Premature Ejaculation
- What is being tested?
- exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Mar 2026to 10 Jul 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 45 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Male individuals aged 25-45 years
- Individuals diagnosed with erectile dysfunction and premature ejaculation
- Individuals who voluntarily agree to participate in the study and sign the informed consent form
- Individuals who have the physical and cognitive capacity to participate in pelvic floor physiotherapy applications
Who cannot join
- Individuals with a history of surgery in the pelvic region
- Individuals with a diagnosis of neurological disease or neurological disorder that may affect pelvic floor muscle function
- Presence of active infection, inflammation, or painful pathology in the pelvic region
- Individuals who regularly use medications that significantly affect sexual function
- Individuals with serious psychiatric illness or cognitive impairment that may hinder study compliance
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Uskudar university
Istanbul
Ömer Şevgi, omer.sevgin@uskudar.edu.tr
About this study
Official title: The Effectiveness of Exercise in the Treatment of Erectile Dysfunction and Premature Ejaculation: a Randomized Controlled Trial.
The aim is to investigate the effectiveness of exercise in the treatment of erectile dysfunction and premature ejaculation.
Read the detailed description
The study was designed as a randomized controlled trial. Participants were divided into two equal groups: a control group and an exercise group. Patients in the control group were followed with normal conventional medical treatment, while participants in the exercise group underwent an 8-week, 3-day-a-week exercise program. All participants were evaluated before and after treatment using the Index of Erectile Function, the World Health Organization Quality of Life Short Form, and the Premature Ejaculation Diagnostic Tool.
- Conditions
- Erectile Dysfunction, Premature Ejaculation
- Being tested
- control, exercise
- Medical subject headings
- Erectile Dysfunction, Premature Ejaculation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
controlOther
Also called medical treatment
Patients in the control group will be followed with normal conventional medical treatment.
exerciseOther
Also called Pelvic Floor Exercise Group
Participants in the exercise group will undergo an 8-week, 3-day-a-week exercise program.
| Study group | Role | What they receive |
|---|---|---|
| control group | Active comparator | only patients who receive medical treatment and informational training Receives: Other: control |
| exercise group | Experimental | Patients who receive pelvic floor exercises in addition to medical treatment and education. Receives: Other: exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
International Index of Erectile Dysfunction
Mean change in International Index of Erectile Dysfunction scores. There are five specific areas addressed including Erectile Function (questions:1-5 \& 15;score range: 0-5, maximum score:30); Orgasmic Function (questions:9-10; score range:0-5; maximum score:10); Sexual desire (questions:11-12; score range:1-5; maximum score:10); Intercourse satisfaction (questions:6-8; score range:0-5; maximum score:15); Overall satisfaction (questions:13-14; score range:1-5; maximum score:10). The lower the score represents greater dysfunction within each domain.
Measured: 10 weeks
Premature Ejaculation Diagnostic Tool
it was developed by Symonds et al. (2007) to better define premature ejaculation for use in clinical studies, this is a 5-point Likert-type scale consisting of 5 items. The scale was adapted to Turkish by Serefoglu et al. (2009). The highest score that can be obtained from the scale is 20.0 and the lowest score is 0.0. Scores higher than 11 are defined as "Premature Ejaculation", scores of 9-10 are defined as "possible Premature Ejaculation", and scores of eight or less are defined as "no Premature Ejaculation".
Measured: 10 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Mar 2026
- Study start1 Mar 2026
- Primary completion30 May 2026 (estimated)
- Study completion10 Jul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Erectile DysfunctionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Uskudar University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Doç.Dr.Ömer Şevgin, Uskudar University
- Investigators
- Parsa Keihani, Study chair, Uskudar University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07442396
- Sponsor's protocol ID
- Uskudar93
- Status last verified
- Mar 2026
- First submitted
- 25 Feb 2026
- Last updated
- 3 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Yaacov D, Nelinger G, Kalichman L. The Effect of Pelvic Floor Rehabilitation on Males with Sexual Dysfunction: A Narrative Review. Sex Med Rev. 2022 Jan;10(1):162-167. doi: 10.1016/j.sxmr.2021.02.001. Epub 2021 Apr 27.
PubMed 33931383Sahin E, Brand A, Cetindag EN, Messelink B, Yosmaoglu HB. Pelvic physical therapy for male sexual disorders: a narrative review. Int J Impot Res. 2025 Dec;37(12):941-949. doi: 10.1038/s41443-025-01034-5. Epub 2025 Feb 27.
PubMed 40016382Niu C, Ventus D, Wen G, Santtila P. Associations between self-reports of physical activity, interoceptive awareness, autonomic regulation, premature ejaculation, and erectile dysfunction in Chinese men. Int J Impot Res. 2025 Dec;37(12):992-1001. doi: 10.1038/s41443-025-01072-z. Epub 2025 Apr 19.
PubMed 40251377
Study at a glance
From the registry record, last updated by the sponsor on 3 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effectiveness of Exercise in the Treatment of Erectile Dysfunction and Premature Ejaculation: a Randomized Controlled Trial.
- ClinicalTrials.gov ID
- NCT07442396
- Acronym / sponsor ID
- Uskudar93
- Conditions
- Erectile Dysfunction, Premature Ejaculation
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Uskudar UniversityUniversity, hospital or other
- Study start
- 1 Mar 2026 (actual)
- Primary completion
- 30 May 2026 (estimated)
- Study completion
- 10 Jul 2026 (estimated)
- First posted
- 2 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim is to investigate the effectiveness of exercise in the treatment of erectile dysfunction and premature ejaculation.
Detailed description
The study was designed as a randomized controlled trial. Participants were divided into two equal groups: a control group and an exercise group. Patients in the control group were followed with normal conventional medical treatment, while participants in the exercise group underwent an 8-week, 3-day-a-week exercise program. All participants were evaluated before and after treatment using the Index of Erectile Function, the World Health Organization Quality of Life Short Form, and the Premature Ejaculation Diagnostic Tool.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| control group | Active comparator | Other: controlonly patients who receive medical treatment and informational training |
| exercise group | Experimental | Other: exercisePatients who receive pelvic floor exercises in addition to medical treatment and education. |
Who may qualify
- Ages
- 25 to 45 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Male individuals aged 25-45 years
- Individuals diagnosed with erectile dysfunction and premature ejaculation
- Individuals who voluntarily agree to participate in the study and sign the informed consent form
- Individuals who have the physical and cognitive capacity to participate in pelvic floor physiotherapy applications
Key exclusion criteria (5 listed)
- Individuals with a history of surgery in the pelvic region
- Individuals with a diagnosis of neurological disease or neurological disorder that may affect pelvic floor muscle function
- Presence of active infection, inflammation, or painful pathology in the pelvic region
- Individuals who regularly use medications that significantly affect sexual function
- Individuals with serious psychiatric illness or cognitive impairment that may hinder study compliance
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| controlAlso: medical treatmentPatients in the control group will be followed with normal conventional medical treatment. | Other | control group |
| exerciseAlso: Pelvic Floor Exercise GroupParticipants in the exercise group will undergo an 8-week, 3-day-a-week exercise program. | Other | exercise group |
Primary outcome
International Index of Erectile Dysfunction
Time frame: 10 weeks
Mean change in International Index of Erectile Dysfunction scores. There are five specific areas addressed including Erectile Function (questions:1-5 \& 15;score range: 0-5, maximum score:30); Orgasmic Function (questions:9-10; score range:0-5; maximum score:10); Sexual desire (questions:11-12; score range:1-5; maximum score:10); Intercourse satisfaction (questions:6-8; score range:0-5; maximum score:15); Overall satisfaction (questions:13-14; score range:1-5; maximum score:10). The lower the score represents greater dysfunction within each domain.
Premature Ejaculation Diagnostic Tool
Time frame: 10 weeks
it was developed by Symonds et al. (2007) to better define premature ejaculation for use in clinical studies, this is a 5-point Likert-type scale consisting of 5 items. The scale was adapted to Turkish by Serefoglu et al. (2009). The highest score that can be obtained from the scale is 20.0 and the lowest score is 0.0. Scores higher than 11 are defined as "Premature Ejaculation", scores of 9-10 are defined as "possible Premature Ejaculation", and scores of eight or less are defined as "no Premature Ejaculation".
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Mar 2026.
- Background: PubMed 33931383Yaacov D, Nelinger G, Kalichman L. The Effect of Pelvic Floor Rehabilitation on Males with Sexual Dysfunction: A Narrative Review. Sex Med Rev. 2022 Jan;10(1):162-167. doi: 10.1016/j.sxmr.2021.02.001. Epub 2021 Apr 27.
- Background: PubMed 40016382Sahin E, Brand A, Cetindag EN, Messelink B, Yosmaoglu HB. Pelvic physical therapy for male sexual disorders: a narrative review. Int J Impot Res. 2025 Dec;37(12):941-949. doi: 10.1038/s41443-025-01034-5. Epub 2025 Feb 27.
- Background: PubMed 40251377Niu C, Ventus D, Wen G, Santtila P. Associations between self-reports of physical activity, interoceptive awareness, autonomic regulation, premature ejaculation, and erectile dysfunction in Chinese men. Int J Impot Res. 2025 Dec;37(12):992-1001. doi: 10.1038/s41443-025-01072-z. Epub 2025 Apr 19.
- Individual participant dataSharing planned: No
Related trials for Erectile Dysfunction
Recruiting
Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment
Prostate Cancer, Urinary Incontinence
Recruiting
Platelet-Rich Plasma for Erectile Dysfunction After Radical Prostatectomy
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Not yet recruiting
Erectile Function PRESERVation in Definitive Radiotherapy for Prostate Cancer by MRI-Enhanced Adaptive Sparing of the Neurovascular Bundle
Prostate Cancer, Localized Prostate Carcinoma
RecruitingPhase 4
Assessment of the Value of FAPI and FDG-PET-CT in Diagnosis of Acute Phase Peyronie's Disease
Peyronie's Disease
RecruitingPhase 3
A Study to Evaluate Efficacy and Safety of HIP2602 in Erectile Dysfunction Patients
Erectile Dysfunction
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Parsa Keihani study chair
Uskudar University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing exercise in people with Erectile Dysfunction and Premature Ejaculation, run by Uskudar University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 3 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ömer ŞEVGİN (+905069787535, omer.sevgin@uskudar.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
International Index of Erectile Dysfunction (time frame: 10 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07442396, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Mar 2026.