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Physical PerformanceNCT07440615

Lower-Limb Muscle Mass and Cardiovascular and Muscular Performance in Males and Females

A study testing Physical Performance Assessment in people with Physical Performance and Leg Muscle Mass, run by Uludag University at 1 site in Turkey (Türkiye).

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

The aim of this study will be to examine the relationship between leg muscle mass and muscle strength, aerobic capacity, anaerobic power, and jumping performance in young adults. In addition, these physical performance measures will be compared between male and female participants. Read more about this study

Who is it for?
Ages 18 to 30 yearsHealthy volunteers can take part
What is being tested?
Physical Performance Assessment
Could I receive a placebo?
No, everyone receives an active treatment
How many people
235 participants
Where
1 siteTurkey (Türkiye)
Study dates
20 Feb 2026to 15 Aug 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 30 years
  • All sexes
  • Healthy volunteers accepted
  • Adult

Who may be able to join

  • absent of lower body injuries that could impact testing;
  • were moderately physically active
  • did not ingest ergogenic aids or stimulant drugs for at least 6 months prior to the start of the study.

Who cannot join

  • -

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Tuncay ALPARSLAN, Assoc.Prof. contact

Türkiye ext. 5058221661

tuncayalparslan@hotmail.com

Turkey (Türkiye)1 site, 1 recruiting

  • Aeromedical Research and Training Center (ARTC)

    Eskişehir, 26000

    Tuncay ALPARSLAN, Assoc. Prof., +905058221661, tuncayalparslan@hotmail.com

    Recruiting

Other trials in Turkey (Türkiye)

About this study

Official title: The Relationship Between Lower-limb Muscle Mass and Cardiovascular and Muscular Performance in Males and Females.

The aim of this study will be to examine the relationship between leg muscle mass and muscle strength, aerobic capacity, anaerobic power, and jumping performance in young adults. In addition, these physical performance measures will be compared between male and female participants.

Recreationally active young adults will be recruited to participate in the study. Body weight and leg muscle mass will be assessed using a body composition analyzer. Participants will perform isokinetic and isometric leg strength tests, an aerobic fitness test (VO₂max), an anaerobic power test (Wingate), and a countermovement jump (CMJ) test.

This study aims to improve the understanding of the effects of leg muscle mass on physical performance and to identify possible differences between males and females. The findings are expected to contribute to exercise prescription, performance assessment, and future research in sports and health sciences.

Being tested
Physical Performance Assessment
Keywords
lean mass, isokinetic, isometric, aerobic capacity, force

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Physical Performance AssessmentOther

    Muscle Isokinetic Strength Testing, Leg Muscle Mass, and Aerobic and Anaerobic Performance Testing, Contermovement Jump

Study groups in NCT07440615
Study groupRoleWhat they receive
Young Adult Participants Healthy Recreationally Active AdultsExperimentalMale and Female Participant
Receives: Other: Physical Performance Assessment

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Leg Muscle Mass-Related Physical Performance Measures

    Measurement tool: Bioelectrical Impedance Analyzer (InBody 270, Biospace Co., South Korea) Description: Segmental lower-limb muscle mass (kg) measured using multi-frequency bioelectrical impedance analysis.

    Unit: kg Time Frame: Baseline (single assessment)

    Measured: Baseline

  2. Muscle Isokinetic Strength

    Measurement tool: Isokinetic dynamometer (Humac Norm, Computer Sports Medicine Inc., USA) Description: Peak torque of dominant leg knee flexors and extensors measured at 60°·s-¹ and normalized to body weight.

    Unit: Nm·kg-¹ Time Frame: Baseline

    Measured: Baseline

  3. Anaerobic Power

    Measurement tool: Wingate Anaerobic Test performed on cycle ergometer (Wattbike WPM Model B, UK) Description: Relative peak anaerobic power calculated during 30-s Wingate test and normalized to body weight.

    Unit: W·kg-¹ Time Frame: Baseline

    Measured: Baseline

  4. Countremovement Jump

    Measurement tool: SmartJump contact mat system (Fusion Sport, Queensland, Australia) Description: Vertical jump height measured during the Countermovement Jump test. Jump height is calculated automatically from flight time using the SmartJump performance measurement system.

    Scale description: Countermovement Jump Height (centimeters). Typical physiological range in healthy young adults is approximately 10-60 cm.

    Interpretation: Higher values indicate better lower-body explosive performance. Unit: cm Time Frame: Baseline (up to 8 weeks)

    Measured: Baseline

  5. Aerobic Capacity

    Measurement tool: Breath-by-breath metabolic gas analyzer (Cosmed Quark CPET) during Bruce treadmill protocol Description: Maximal oxygen consumption determined according to standard VO₂max criteria.

    Unit: ml·kg-¹·min-¹ Time Frame: Baseline

    Measured: Baseline

  6. Muscle Isometric Strength

    Measurement tool: Leg dynamometer (Takei T.K.K. 5402, Takei Scientific Instruments, Japan) Description: Maximal voluntary isometric force normalized to body weight. Highest value of three trials recorded.

    Unit: kg·kg-¹ Time Frame: Baseline

    Measured: Baseline

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted27 Feb 2026
  2. Study start20 Feb 2026
  3. Primary completion5 Jun 2026 (estimated)
  4. Study completion15 Aug 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Basic science
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrolment
235 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07440615
Sponsor's protocol ID
E-87914409-050.04-87583
Status last verified
Feb 2026
First submitted
5 Jan 2026
Last updated
9 Jun 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Amaral JF, Alvim FC, Castro EA, Doimo LA, Silva MV, Novo Junior JM. Influence of aging on isometric muscle strength, fat-free mass and electromyographic signal power of the upper and lower limbs in women. Braz J Phys Ther. 2014 Mar-Apr;18(2):183-90. doi: 10.1590/s1413-35552012005000145. Epub 2014 Mar 19.

    PubMed 24676705

  • Boraczynski M, Boraczynski T, Podstawski R, Wojcik Z, Gronek P. Relationships Between Measures of Functional and Isometric Lower Body Strength, Aerobic Capacity, Anaerobic Power, Sprint and Countermovement Jump Performance in Professional Soccer Players. J Hum Kinet. 2020 Oct 31;75:161-175. doi: 10.2478/hukin-2020-0045. eCollection 2020 Oct.

    PubMed 33312304

  • Bullo V, Roma E, Gobbo S, Duregon F, Bergamo M, Bianchini G, Doria E, Cugusi L, Blasio AD, Bocalini DS, Ermolao A, Bergamin M. Lower Limb Strength Profile in Elderly with Different Pathologies: Comparisons with Healthy Subjects. Geriatrics (Basel). 2020 Oct 22;5(4):83. doi: 10.3390/geriatrics5040083.

    PubMed 33105620

  • Comfort P, McMahon JJ, Lake JP, Ripley NJ, Triplett NT, Haff GG. Relative strength explains the differences in multi-joint rapid force production between sexes. PLoS One. 2024 Feb 15;19(2):e0296877. doi: 10.1371/journal.pone.0296877. eCollection 2024.

    PubMed 38359039

  • Cuesta-Vargas A, Gonzalez-Sanchez M. Correlation between architectural variables and torque in the erector spinae muscle during maximal isometric contraction. J Sports Sci. 2014;32(19):1797-804. doi: 10.1080/02640414.2014.924054. Epub 2014 Jun 6.

    PubMed 24903060

  • Driller MW, Argus CK, Shing CM. The reliability of a 30-s sprint test on the Wattbike cycle ergometer. Int J Sports Physiol Perform. 2013 Jul;8(4):379-83. doi: 10.1123/ijspp.8.4.379.

    PubMed 23863304

  • Farinatti P, Castinheiras Neto AG, Amorim PR. Oxygen Consumption and Substrate Utilization During and After Resistance Exercises Performed with Different Muscle Mass. Int J Exerc Sci. 2016 Jan 15;9(1):77-88. doi: 10.70252/AKBM3973. eCollection 2016.

    PubMed 27293507

  • Harris-Love MO, Benson K, Leasure E, Adams B, McIntosh V. The Influence of Upper and Lower Extremity Strength on Performance-Based Sarcopenia Assessment Tests. J Funct Morphol Kinesiol. 2018 Dec;3(4):53. doi: 10.3390/jfmk3040053. Epub 2018 Nov 3.

    PubMed 30533549

  • Laffaye G, Wagner PP, Tombleson TI. Countermovement jump height: gender and sport-specific differences in the force-time variables. J Strength Cond Res. 2014 Apr;28(4):1096-105. doi: 10.1519/JSC.0b013e3182a1db03.

    PubMed 23838969

Questions about this trial

What is this clinical trial studying?

A study testing Physical Performance Assessment in people with Physical Performance and Leg Muscle Mass, run by Uludag University at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 9 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Tuncay ALPARSLAN, Assoc.Prof. (Türkiye ext. 5058221661, tuncayalparslan@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Leg Muscle Mass-Related Physical Performance Measures (time frame: Baseline). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07440615, which also lists 9 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Jun 2026.

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