Quadriplegic Cerebral PalsyNCT07420244
Task-oriented Training Versus Group Circuit Training in Children With Quadriplegic Cerebral Palsy
A study testing Task-Oriented Circuit Training and Group Circuit Training in people with Quadriplegic Cerebral Palsy, run by University of Lahore.
Trial summary
Cerebral palsy is a common neurodevelopmental disorder that affects movement, posture, and functional abilities in children. This randomized controlled trial focuses on comparing the effects of task-oriented circuit training and group circuit training on functional performance and functional capacity in children with… Read more about this study
- Who is it for?
- Ages 7 to 12 years
- Conditions the study is for
- Quadriplegic Cerebral Palsy
- What is being tested?
- Task-Oriented Circuit Training and Group Circuit Training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- No sites listed yet
- Study dates
- 1 Mar 2026to 1 Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 7 to 12 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Children diagnosed with spastic quadriplegic cerebral palsy.
- Age between 7 and 12 years.
- Gross Motor Function Classification System (GMFCS) level II or III.
- Both genders.
- Lower limb spasticity graded between 1 and 1+ on the Modified Ashworth Scale.
- Ability to understand and follow simple instructions.
- No serious or recurrent medical complications.
Who cannot join
- Presence of fixed orthopedic deformities affecting balance or movement.
- Visual, auditory, vestibular, or perceptual deficits.
- History of seizures or epilepsy.
- Orthopedic surgery or botulinum toxin injections within the past 6 months.
- Participation in other structured rehabilitation programs during the study period.
- Presence of neuromuscular disorders other than cerebral palsy.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
Dr. Wardah Rauf Physiotherapist, DPT, MSPT-N contact
About this study
Official title: Task-oriented Training Versus Group Circuit Training in Children With Quadriplegic Cerebral
Cerebral palsy is a common neurodevelopmental disorder that affects movement, posture, and functional abilities in children. This randomized controlled trial focuses on comparing the effects of task-oriented circuit training and group circuit training on functional performance and functional capacity in children with quadriplegic cerebral palsy. Outcomes will be measured using the Gross Motor Function Measure (GMFM-88) and the Activities Scale for Kids-Capability version (ASK-C). The findings of this study may help identify effective rehabilitation strategies for improving functional outcomes in children with cerebral palsy.
Read the detailed description
Cerebral palsy (CP) is a non-progressive neurological disorder characterized by impairments in movement, posture, and functional abilities, significantly limiting a child's participation in daily activities. Children with quadriplegic cerebral palsy experience greater functional limitations, particularly in gross motor performance and functional capacity, necessitating effective and structured rehabilitation interventions.
Task-oriented training and circuit training are commonly used therapeutic approaches in pediatric neurorehabilitation. Task-oriented training focuses on practicing meaningful, goal-directed functional tasks to enhance motor learning and functional performance whereas group circuit training emphasizes repetitive, structured exercises performed in a circuit format to improve strength, endurance, and motor skills. However, limited evidence exists comparing the effectiveness of these two approaches specifically in children with quadriplegic cerebral palsy.
This randomized controlled trial aims to compare the effects of task-oriented circuit training and group circuit training on functional performance and functional capacity in children with quadriplegic cerebral palsy. Eligible participants will be randomly allocated into two intervention groups. One group will receive task-oriented circuit training combined with conventional physical therapy, while the other group will receive group circuit training along with conventional physical therapy.
Functional performance will be assessed using the Gross Motor Function Measure-88 (GMFM-88), and functional capacity will be evaluated using the Activities Scale for Kids-Capability version (ASK-C). Assessments will be conducted at baseline (pre-intervention) and after completion of the intervention period (post-intervention).
The results of this study are expected to provide evidence regarding the comparative effectiveness of task-oriented circuit training and group circuit training, thereby assisting clinicians in selecting appropriate rehabilitation strategies to improve functional outcomes in children with quadriplegic cerebral palsy.
- Conditions
- Quadriplegic Cerebral Palsy
- Being tested
- Task-Oriented Circuit Training, Group Circuit Training
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Task-Oriented Circuit TrainingOther
Task-oriented circuit training will include goal directed functional tasks such as sit-to-stand activities, balance tasks, walking-related activities, and functional mobility tasks arranged in a circuit format. The intervention will focus on improving functional performance through repetitive practice of meaningful tasks.
Group Circuit TrainingOther
Group circuit training will consist of structured exercise stations that focus on strength, balance, endurance, and gross motor activities, all performed in a group setting. Exercises will be performed in a circuit format under therapist supervision.
| Study group | Role | What they receive |
|---|---|---|
| Task-Oriented Circuit Training Group | Experimental | Participants in this group will receive task-oriented circuit training combined with conventional physical therapy. Receives: Other: Task-Oriented Circuit Training |
| Group Circuit Training Group | Active comparator | Participants in this group will receive a combination of group circuit training and conventional physical therapy. Receives: Other: Group Circuit Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Functional Performance
Functional performance will be assessed using the Gross Motor Function Measure-88 (GMFM-88), which evaluates gross motor abilities across five dimensions (lying/rolling, sitting, crawling/kneeling, standing, walking/running).
Ordinal scale 0-3 (0=does not initiate, 3=completes), resulting in a percentage score (0-100%) for each dimension and total score.
Measured: From baseline to the end of treatment at 16 weeks
Functional Capacity
Functional capacity will be measured using the Activities Scale for Kids-Capability version (ASK-C), a validated questionnaire assessing a child's ability to perform daily activities.
This scale consists of 30 items, each rated on a 5-point ordinal scale. 0= with no problem
- with a little problem
- with a moderate problem
- with a big problem
- I could not The final score ranges from 0 to 100, with a higher score indicating better functional outcomes
Measured: From baseline to the end of treatment at 16 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Feb 2026
- Study start1 Mar 2026 (estimated)
- Primary completion1 Aug 2026 (estimated)
- Study completion1 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Quadriplegic Cerebral PalsyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 36 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Lahore
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Noor Fatima, MSPT- Neurology, Principal investigator, University of Lahore
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07420244
- Sponsor's protocol ID
- UOL/IREB/25/15/03/31
- Status last verified
- Dec 2025
- First submitted
- 21 Dec 2025
- Last updated
- 19 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared to protect participant confidentiality and because the data are collected as part of an academic research thesis.
Study at a glance
From the registry record, last updated by the sponsor on 19 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Task-oriented Training Versus Group Circuit Training in Children With Quadriplegic Cerebral
- ClinicalTrials.gov ID
- NCT07420244
- Acronym / sponsor ID
- UOL/IREB/25/15/03/31
- Conditions
- Quadriplegic Cerebral Palsy
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 36 participants (estimated)
- Lead sponsor
- University of LahoreUniversity, hospital or other
- Study start
- 1 Mar 2026 (estimated)
- Primary completion
- 1 Aug 2026 (estimated)
- Study completion
- 1 Sep 2026 (estimated)
- First posted
- 19 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Cerebral palsy is a common neurodevelopmental disorder that affects movement, posture, and functional abilities in children. This randomized controlled trial focuses on comparing the effects of task-oriented circuit training and group circuit training on functional performance and functional capacity in children with quadriplegic cerebral palsy. Outcomes will be measured using the Gross Motor Function Measure (GMFM-88) and the Activities Scale for Kids-Capability version (ASK-C). The findings of this study may help identify effective rehabilitation strategies for improving functional outcomes in children with cerebral palsy.
Detailed description
Cerebral palsy (CP) is a non-progressive neurological disorder characterized by impairments in movement, posture, and functional abilities, significantly limiting a child's participation in daily activities. Children with quadriplegic cerebral palsy experience greater functional limitations, particularly in gross motor performance and functional capacity, necessitating effective and structured rehabilitation interventions.
Task-oriented training and circuit training are commonly used therapeutic approaches in pediatric neurorehabilitation. Task-oriented training focuses on practicing meaningful, goal-directed functional tasks to enhance motor learning and functional performance whereas group circuit training emphasizes repetitive, structured exercises performed in a circuit format to improve strength, endurance, and motor skills. However, limited evidence exists comparing the effectiveness of these two approaches specifically in children with quadriplegic cerebral palsy.
This randomized controlled trial aims to compare the effects of task-oriented circuit training and group circuit training on functional performance and functional capacity in children with quadriplegic cerebral palsy. Eligible participants will be randomly allocated into two intervention groups. One group will receive task-oriented circuit training combined with conventional physical therapy, while the other group will receive group circuit training along with conventional physical therapy.
Functional performance will be assessed using the Gross Motor Function Measure-88 (GMFM-88), and functional capacity will be evaluated using the Activities Scale for Kids-Capability version (ASK-C). Assessments will be conducted at baseline (pre-intervention) and after completion of the intervention period (post-intervention).
The results of this study are expected to provide evidence regarding the comparative effectiveness of task-oriented circuit training and group circuit training, thereby assisting clinicians in selecting appropriate rehabilitation strategies to improve functional outcomes in children with quadriplegic cerebral palsy.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Task-Oriented Circuit Training Group | Experimental | Other: Task-Oriented Circuit TrainingParticipants in this group will receive task-oriented circuit training combined with conventional physical therapy. |
| Group Circuit Training Group | Active comparator | Other: Group Circuit TrainingParticipants in this group will receive a combination of group circuit training and conventional physical therapy. |
Who may qualify
- Ages
- 7 to 12 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (7 listed)
- Children diagnosed with spastic quadriplegic cerebral palsy.
- Age between 7 and 12 years.
- Gross Motor Function Classification System (GMFCS) level II or III.
- Both genders.
- Lower limb spasticity graded between 1 and 1+ on the Modified Ashworth Scale.
Key exclusion criteria (6 listed)
- Presence of fixed orthopedic deformities affecting balance or movement.
- Visual, auditory, vestibular, or perceptual deficits.
- History of seizures or epilepsy.
- Orthopedic surgery or botulinum toxin injections within the past 6 months.
- Participation in other structured rehabilitation programs during the study period.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Task-Oriented Circuit TrainingTask-oriented circuit training will include goal directed functional tasks such as sit-to-stand activities, balance tasks, walking-related activities, and functional mobility tasks arranged in a circuit format. The intervention will focus on improving functional performance through repetitive practice of meaningful tasks. | Other | Task-Oriented Circuit Training Group |
| Group Circuit TrainingGroup circuit training will consist of structured exercise stations that focus on strength, balance, endurance, and gross motor activities, all performed in a group setting. Exercises will be performed in a circuit format under therapist supervision. | Other | Group Circuit Training Group |
Primary outcome
Functional Performance
Time frame: From baseline to the end of treatment at 16 weeks
Functional performance will be assessed using the Gross Motor Function Measure-88 (GMFM-88), which evaluates gross motor abilities across five dimensions (lying/rolling, sitting, crawling/kneeling, standing, walking/running). Ordinal scale 0-3 (0=does not initiate, 3=completes), resulting in a percentage score (0-100%) for each dimension and total score.
Functional Capacity
Time frame: From baseline to the end of treatment at 16 weeks
Functional capacity will be measured using the Activities Scale for Kids-Capability version (ASK-C), a validated questionnaire assessing a child's ability to perform daily activities. This scale consists of 30 items, each rated on a 5-point ordinal scale. 0= with no problem 1. with a little problem 2. with a moderate problem 3. with a big problem 4. I could not The final score ranges from 0 to 100, with a higher score indicating better functional outcomes
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Feb 2026.
- Individual participant dataSharing planned: No. Individual participant data will not be shared to protect participant confidentiality and because the data are collected as part of an academic research thesis.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Dr. Wardah Rauf Physiotherapist, DPT, MSPT-N contact
Noor Fatima, MSPT- Neurology principal investigator
University of Lahore
Questions about this trial
What is this clinical trial studying?
A study testing Task-Oriented Circuit Training and Group Circuit Training in people with Quadriplegic Cerebral Palsy, run by University of Lahore.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 19 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Noor Fatima, MSPT Neurology (03026699547, 70076588@student.uol.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Functional Performance (time frame: From baseline to the end of treatment at 16 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Feb 2026.