Idiopathic ScoliosisISNCT07413588
Implementation of Specific Tailored Exercises Program Versus Exergaming Exercises on Cobb Angle in the Treatment of Adolescent Idiopathic Scoliosis.
A study testing Specific Tailored Exercises Program, Exergaming Exercises and traditional physical therapy in people with Idiopathic Scoliosis, run by Cairo University.
Trial summary
this study will be conducted to investigate the difference between specific tailored exercise program and exergaming exercises on Cobb's angle, angle of trunk rotation, pulmonary function and quality of the life in adolescent idiopathic scoliosis. Read more about this study
- Who is it for?
- Ages 10 to 18 years
- Conditions the study is for
- Idiopathic Scoliosis
- What is being tested?
- Specific Tailored Exercises Program, Exergaming Exercises and traditional physical therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 54 participants
- Where
- No sites listed yet
- Study dates
- 10 Feb 2026to 10 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 to 18 years
- All sexes
- No healthy volunteers
- Child, Adult
Who may be able to join
- Thoracic spine region with C-shaped scoliosis
- Individuals aged 10-18 years
- Cobb's angle from 10 to 25 degrees
- Both genders (male and female)
- Adolescent idiopathic scoliosis
Who cannot join
- Mental health disorders
- Neuromuscular or rheumatic diseases
- A history of spinal surgery
- Patients been prescribed brace treatment
- Leg length discrepancy
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Implementation of Specific Tailored Exercises Program Versus Exergaming Exercises on Cobb Angle in the Treatment of Adolescent Idiopathic Scoliosis: a Randomized Controlled Trial
this study will be conducted to investigate the difference between specific tailored exercise program and exergaming exercises on Cobb's angle, angle of trunk rotation, pulmonary function and quality of the life in adolescent idiopathic scoliosis.
Read the detailed description
Adolescent idiopathic scoliosis is a structural spinal disorder that occurs during puberty and lacks a definitive etiology. The spinal deviation of the thoracic region occurs more frequently in adolescent and typical manifestations may include noticeable spinal deformities, impair posture and restrict body movement . Existing studies on scoliosis-specific exercises like Schroth, lyon and side shifts approaches have shown positive outcomes in reducing curvature progression and enhancing postural stability. Also, the exergaming exercises enhance postural deformity by providing real-time body movement of postural correction exercises through games.However, research on the tailored program for AIS is limited, leading to uncertainties about it's their clearance effect. Recent literature underscores the need for standardized protocols.The current study aims to assess the evidence of the specific tailored program based on differential approaches of the scoliosis specific exercises as (schroth, lyon and side shifts) methods. Also, asses the evidence of the specific customized tailored exergaming exercises, to identifying their impact on cobb's angle, angle of trunk rotation, pulmonary function and quality of life.
- Conditions
- Idiopathic Scoliosis
- Being tested
- Specific Tailored Exercises Program, Exergaming Exercises, traditional physical therapy
- Keywords
- Tailored Exercises Program, Exergaming Exercises, Cobb Angle, Adolescent Idiopathic Scoliosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Specific Tailored Exercises ProgramOther
the patients will receive a specific tailored exercise program in the form of corrective exercises, positioning, mirror therapy, ADL adaptation, and instructions in addition to traditional physical therapy treatment.
Exergaming ExercisesOther
Every participant in group B will be received an exergaming exercises in form of a series of Kinect training game, sports island freedom game . dance evolution game and Kinect sports games designed for Xbox 360 Kinect console. The games will be projected onto a 24-Inch screen monitor. Each session consisted of playing 1-2 trials in a row of each game for 45-60 minutes in addition to traditional physical therapy
traditional physical therapyOther
the patients will receive traditional treatment only of the intervention in the form of stretching, strengthening, core stabilization and breathing exercises
| Study group | Role | What they receive |
|---|---|---|
| Specific Tailored Exercises Program | Experimental | eighteen patients will receive Specific Tailored Exercises Program plus traditional physical therapy three times per week for three months Receives: Other: Specific Tailored Exercises Program; Other: traditional physical therapy |
| Exergaming Exercises | Experimental | eighteen patients will receive Exergaming Exercises plus traditional physical therapy three times per week for three months Receives: Other: Exergaming Exercises; Other: traditional physical therapy |
| traditional physical therapy | Active comparator | eighteen patients will receive traditional physical therapy three times per week for three months Receives: Other: traditional physical therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cobb's angle
cobbs angle will be measured by x-ray. This method quantifies the lateral spinal curvature measured on a radiograph in the coronal plane, using anterior-posterior (AP) or posterior-anterior (PA) radiographs.A Cobb angle in the range of 10 to 20 degrees is considered as mild scoliosis. Scoliosis severity is moderate when the Cobb angle ranges from 20 to 40 degrees.
Measured: up to three months
the angle of trunk rotation
Scoliometer mobile applications is a valid and reliable method used to assess the angle of trunk rotation. It is a portable, accessible and easy tracking and follow up. Visual interface and digital readout. Save and track angle trunk rotation values over time
Measured: up to three months
flow rate of inhalation
The flow rate of inhalation in respiratory physiology refers to the rate at which air moves into the lungs during inspiration, i.e., The volume of air that enters the lungs per unit of time during inspiration. (e.g., mL/sec ). In a flow-based incentive spirometer, this flow rate is indicated by rising elements (e.g., balls) in the device that reflect how quickly air is drawn in during inspiration. For proper medication delivery from a Dry Powder Inhaler (DPI), a flow rate of inhalation of greater than 60 L/min is generally considered optimal.
Measured: up to three months
Secondary outcomes (1)
life disability
It will be measured by the Arabic version of the Scoliosis Research Society -22 Questionnaire (SRS-22). The scale consists of 22 questions and 5 subdimensions, namely, pain, self-image, spinal functions, mental health, and treatment satisfaction. All of these sections are evaluated separately or by summing all questions under a total result score. Scores were calculated by assigning a value between 1 and 5 for each question. Accordingly, the lowest total score of the survey was 1, and the highest total score was 5, with higher scores indicating better QoL.
Measured: up to three months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Feb 2026
- Study start10 Feb 2026 (estimated)
- Primary completion10 Dec 2026 (estimated)
- Study completion10 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Idiopathic ScoliosisStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- specific Tailored Exercises Program and Exergaming Exercises
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 54 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Randa Ahmed Amin, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07413588
- Sponsor's protocol ID
- P.T.REC/012/006202
- Acronym
- IS
- Status last verified
- Feb 2026
- First submitted
- 30 Jan 2026
- Last updated
- 17 Feb 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Implementation of Specific Tailored Exercises Program Versus Exergaming Exercises on Cobb Angle in the Treatment of Adolescent Idiopathic Scoliosis: a Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07413588
- Acronym / sponsor ID
- IS / P.T.REC/012/006202
- Conditions
- Idiopathic Scoliosis
- Keywords
- Tailored Exercises Program, Exergaming Exercises, Cobb Angle, Adolescent Idiopathic Scoliosis
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 54 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 10 Feb 2026 (estimated)
- Primary completion
- 10 Dec 2026 (estimated)
- Study completion
- 10 Dec 2026 (estimated)
- First posted
- 17 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
this study will be conducted to investigate the difference between specific tailored exercise program and exergaming exercises on Cobb's angle, angle of trunk rotation, pulmonary function and quality of the life in adolescent idiopathic scoliosis.
Detailed description
Adolescent idiopathic scoliosis is a structural spinal disorder that occurs during puberty and lacks a definitive etiology. The spinal deviation of the thoracic region occurs more frequently in adolescent and typical manifestations may include noticeable spinal deformities, impair posture and restrict body movement . Existing studies on scoliosis-specific exercises like Schroth, lyon and side shifts approaches have shown positive outcomes in reducing curvature progression and enhancing postural stability. Also, the exergaming exercises enhance postural deformity by providing real-time body movement of postural correction exercises through games.However, research on the tailored program for AIS is limited, leading to uncertainties about it's their clearance effect. Recent literature underscores the need for standardized protocols.The current study aims to assess the evidence of the specific tailored program based on differential approaches of the scoliosis specific exercises as (schroth, lyon and side shifts) methods. Also, asses the evidence of the specific customized tailored exergaming exercises, to identifying their impact on cobb's angle, angle of trunk rotation, pulmonary function and quality of life.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 3
- Model description
- specific Tailored Exercises Program and Exergaming Exercises
| Arm | Type | Receives |
|---|---|---|
| Specific Tailored Exercises Program | Experimental | Other: Specific Tailored Exercises Program, Other: traditional physical therapyeighteen patients will receive Specific Tailored Exercises Program plus traditional physical therapy three times per week for three months |
| Exergaming Exercises | Experimental | Other: Exergaming Exercises, Other: traditional physical therapyeighteen patients will receive Exergaming Exercises plus traditional physical therapy three times per week for three months |
| traditional physical therapy | Active comparator | Other: traditional physical therapyeighteen patients will receive traditional physical therapy three times per week for three months |
Who may qualify
- Ages
- 10 to 18 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
Key inclusion criteria (5 listed)
- Thoracic spine region with C-shaped scoliosis
- Individuals aged 10-18 years
- Cobb's angle from 10 to 25 degrees
- Both genders (male and female)
- Adolescent idiopathic scoliosis
Key exclusion criteria (5 listed)
- Mental health disorders
- Neuromuscular or rheumatic diseases
- A history of spinal surgery
- Patients been prescribed brace treatment
- Leg length discrepancy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Specific Tailored Exercises Programthe patients will receive a specific tailored exercise program in the form of corrective exercises, positioning, mirror therapy, ADL adaptation, and instructions in addition to traditional physical therapy treatment. | Other | Specific Tailored Exercises Program |
| Exergaming ExercisesEvery participant in group B will be received an exergaming exercises in form of a series of Kinect training game, sports island freedom game . dance evolution game and Kinect sports games designed for Xbox 360 Kinect console. The games will be projected onto a 24-Inch screen monitor. Each session consisted of playing 1-2 trials in a row of each game for 45-60 minutes in addition to traditional physical therapy | Other | Exergaming Exercises |
| traditional physical therapythe patients will receive traditional treatment only of the intervention in the form of stretching, strengthening, core stabilization and breathing exercises | Other | Exergaming Exercises, Specific Tailored Exercises Program, traditional physical therapy |
Primary outcome
Cobb's angle
Time frame: up to three months
cobbs angle will be measured by x-ray. This method quantifies the lateral spinal curvature measured on a radiograph in the coronal plane, using anterior-posterior (AP) or posterior-anterior (PA) radiographs.A Cobb angle in the range of 10 to 20 degrees is considered as mild scoliosis. Scoliosis severity is moderate when the Cobb angle ranges from 20 to 40 degrees.
the angle of trunk rotation
Time frame: up to three months
Scoliometer mobile applications is a valid and reliable method used to assess the angle of trunk rotation. It is a portable, accessible and easy tracking and follow up. Visual interface and digital readout. Save and track angle trunk rotation values over time
flow rate of inhalation
Time frame: up to three months
The flow rate of inhalation in respiratory physiology refers to the rate at which air moves into the lungs during inspiration, i.e., The volume of air that enters the lungs per unit of time during inspiration. (e.g., mL/sec ). In a flow-based incentive spirometer, this flow rate is indicated by rising elements (e.g., balls) in the device that reflect how quickly air is drawn in during inspiration. For proper medication delivery from a Dry Powder Inhaler (DPI), a flow rate of inhalation of greater than 60 L/min is generally considered optimal.
1 secondary outcome
life disability
Time frame: up to three months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Feb 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Specific Tailored Exercises Program, Exergaming Exercises and traditional physical therapy in people with Idiopathic Scoliosis, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 17 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Randa Amin, phd (01013939174, Randaamin1311@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cobb's angle (time frame: up to three months). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Feb 2026.