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Type 2 Diabetes (T2DM)NCT07404280

Impact of a Nutritional Intervention Based on Moroccan Dietary Habits on the Glycemic Control of Type 2 Diabetics

A study testing Moroccan-Adapted Nutritional Plan in people with Type 2 Diabetes (T2DM), run by Avicenna Military Hospital at 1 site in Morocco.

Active, not recruiting

Under way, not looking for participants. Everyone needed has enrolled. The study is still running.

Official record
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Trial summary

The goal of this study is to learn if a nutritional intervention adapted to Moroccan dietary habits can improve blood sugar control in adults with Type 2 Diabetes. The main questions it aims to answer are: Does a personalized diet based on Moroccan culinary traditions improve long-term blood sugar levels (HbA1c)? How… Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Type 2 Diabetes (T2DM)
What is being tested?
Moroccan-Adapted Nutritional Plan
Could I receive a placebo?
No, everyone receives an active treatment
How many people
50 participants
Where
1 siteMorocco
Study dates
1 Oct 2024to Sep 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Confirmed diagnosis of T2D by a healthcare professional.
  • Age 18 years or older.
  • A glycated hemoglobin (HbA1c) level less than 10%.
  • Capacity to provide informed written consent and follow the study procedures.

Who cannot join

  • Non-diabetic subjects.
  • Type 1 diabetes or secondary diabetes.
  • Age younger than 18 years.
  • Pregnancy or planned pregnancy during the study period.
  • HbA1c level greater than 10%.
  • Chronic renal insufficiency or hepatic disease.
  • Pathologies of the digestive tract that affect nutrient absorption.
  • Known food allergies requiring highly specific restricted diets.

Trial locations and contacts

1 site in 1 country.

Morocco1 site

  • Avicenna Military Hospital of Marrakech

    Marrakesh, Marrakesh-Safi, 40160

Other trials in Morocco

About this study

Official title: Intervention of Artificial Intelligence in the Management of Nutritional Therapy Applied to Moroccan Type 2 Diabetics - Al-Khawarizmi Project

The goal of this study is to learn if a nutritional intervention adapted to Moroccan dietary habits can improve blood sugar control in adults with Type 2 Diabetes. The main questions it aims to answer are:

  • Does a personalized diet based on Moroccan culinary traditions improve long-term blood sugar levels (HbA1c)?
  • How does this intervention affect daily blood sugar fluctuations measured as interstitial glucose?
  • Does the intervention lead to changes in body measurements, such as weight and Body Mass Index (BMI)?
Read more

Participants will:

  • Wear a Continuous Glucose Monitor (CGM) to track sugar levels in real-time.
  • Keep a detailed food diary of all foods and drinks consumed.
  • Follow their usual diet for the first 7 days to establish a baseline.
  • Receive personalized dietary advice specifically tailored to Moroccan food habits.
  • Return for clinical check-ups at 14, 90, and 180 days for blood tests and body measurements.
Read the detailed description

This study follows a quasi-experimental, before-after design conducted in a clinical setting. The research is structured to evaluate the metabolic and anthropometric response of Type 2 Diabetic (T2D) patients to a culturally tailored nutritional intervention. The trial is longitudinal, spanning a total duration of 180 days per participant.

Intervention Phases:

The protocol is divided into distinct chronological stages to capture both baseline data and intervention outcomes:

  • Baseline Phase (Days 1-7): Participants maintain their habitual "free" diet to establish a baseline for glycemic variability and caloric intake. During this phase, Continuous Glucose Monitoring (CGM) systems and detailed food diaries are used to map postprandial glucose responses to traditional Moroccan meals.
  • Intervention Initiation (Day 7- T7): A specialized dietitian analyzes the baseline food diaries and CGM cycles to provide personalized nutritional directives. These directives adapt international dietary standards to the specific ingredients, cooking methods, and flavor profiles of Moroccan cuisine.
  • Adjustment and Stabilization (Day 14- T14): A follow-up consultation is held to assess initial adherence and refine the nutritional recommendations based on the participant's feedback and early glycemic data.
  • Medium and Long-term Follow-up (T90 \& T180): Metabolic stability is evaluated at 3 and 6 months. These stages involve comprehensive biological testing and anthropometric measurements to determine the sustainability of the intervention's effects.

Data collection and Scientific tools:

The study utilizes high-precision monitoring tools to ensure data reliability:

  • Continuous Glucose Monitoring (CGM): Sensors are used to record interstitial glucose levels in real-time, providing a more granular view of glycemic control that traditional finger-stick testing.
  • Nutritional Analysis: Food intake is quantified through structured diaries, kitchen scales for portion control, and validated food frequency questionnaires.
  • Anthropometric and metabolic Markers: Bioelectrical impedance analysis (BIA) is used to track body composition changes, while laboratory tests measure HbA1c, fasting blood glucose, and lipid and renal profiles.

Statistical Analysis Plan Data will be analyzed using a within-subject comparison. Descriptive statistics will summarize baseline characteristics. Paired t-tests and ANOVA will be employed to compare glycemic and anthropometric variables across the four time points (T0, T7, T90, T180), with a significance level set to p<0.05. Additionally, Pearson or Spearman correlation tests and Artificial Intelligence techniques will examine the association between specific Moroccan dietary patterns and glycemic fluctuations.

Being tested
Moroccan-Adapted Nutritional Plan
Keywords
Type 2 Diabetes, Artificial Intelligence, Nutritional Intervention, Glycemic Control, Moroccan Dietary Habits, Precision Nutrition
Medical subject headings
Diabetes Mellitus, Type 2

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Moroccan-Adapted Nutritional PlanBehavioural

    The intervention consists of a structured diet plan that integrates traditional Moroccan ingredients and cooking methods while optimizing for glycemic control. It involves:

    • Personalized meal planning based on individual food diaries.
    • Education on carbohydrate counting and portion sizes within the Moroccan culinary context.
    • Use of Continuous Glucose Monitoring (CGM) data to provide real-time feedback on how specific Moroccan meals affect the participant's glucose levels.
Study groups in NCT07404280
Study groupRoleWhat they receive
Experimental: Adapted Nutritional InterventionExperimentalA single group of 50 Type 2 Diabetic patients will participate in a four-stage intervention over 180 days. * Phase 1 (Baseline): Participants will follow their usual, free diet for 7 days while monitored by Continuous Glucose Monitoring (CGM) and food diaries to establish a baseline. * Phase 2 (Intervention): Participants receive personalized nutritional directives specifically adapted to traditional Moroccan dietary habits and culinary practices. * Phase 3 (Follow-up): Continuous monitoring and periodic consultations (at Day 14, Day 90, and Day 180) to adjust the intervention, measure metabolic changes (HbA1c), and evaluate anthropometric parameters.
Receives: Behavioral: Moroccan-Adapted Nutritional Plan

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Change in Interstitial Glucose Levels

    Evaluation of the impact of the Moroccan-adapted nutritional intervention on daily glucose fluctuations. This is measured using a Continuous Glucose Monitoring (CGM) system to record real-time glucose data.

    Measured: Baseline (Day 0 to Day 7) compared to the final follow-up at Day 180.

Secondary outcomes (5)

  1. Change in HbA1c

    Measurement of glycated hemoglobin to assess long-term glycemic control through laboratory samples.

    Measured: Baseline (Day 0) and Day 180.

  2. Change in Body Mass Index (BMI)

    Calculation of BMI based on weight and height measurements.

    Measured: Baseline (Day 0) and Day 180.

  3. Change in Waist Circumference

    Anthropometric measurement of the waist to evaluate changes in abdominal adiposity.

    Measured: Baseline (Day 0) and Day 180.

  4. Change in Body Composition

    Assessment of body fat and lean mass using bioelectrical impedance.

    Measured: Baseline (Day 0) and Day 180.

  5. Dietary Adherence

    Evaluation of changes in dietary habits and adherence to the personalized Moroccan-adapted recommendations using food diaries.

    Measured: Baseline (Day 7) compared to Day 180.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted11 Feb 2026
  2. Study start1 Oct 2024
  3. Primary completionJun 2026 (estimated)
  4. Study completionSep 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrolment
50 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07404280
Sponsor's protocol ID
153/2024/2026
Status last verified
Feb 2026
First submitted
5 Feb 2026
Last updated
12 Feb 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Yes: Individual participant data that underlie the results reported in this study and the final article (text, tables, figures, and appendices), after de-identification, will be made available to researchers who provide a methodologically sound proposal. Request should be directed to the corresponding author. To gain access, data requestors will need to sign a data access agreement.

Questions about this trial

What is this clinical trial studying?

A study testing Moroccan-Adapted Nutritional Plan in people with Type 2 Diabetes (T2DM), run by Avicenna Military Hospital at 1 site in Morocco.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: under way, not looking for participants, as of the sponsor's last update on 12 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Morocco. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Change in Interstitial Glucose Levels (time frame: Baseline (Day 0 to Day 7) compared to the final follow-up at Day 180.). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07404280.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Feb 2026.

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